Knowledge, attitude and practices of antibiotic usage and resistance among the second year MBBS Students

Background: Social aspect of antibiotic management forms a significant way to overcome the rapidly intensifying problem of antibiotic resistance. Knowledge helps in spreading awareness and understanding while attitude and practices influences health related behaviour. Medical students should not only be made aware of the current emerging health issues but also be directed towards rational antibiotics prescribing behaviour as future medical practitioners. Therefore, present study was undertaken to assess the existing knowledge, attitude and practices (KAP) related to antibiotic usage and resistance among second year (fourth semester) MBBS students.Methods: This was a cross-sectional, questionnaire based study conducted in department of pharmacology of a government medical college in Kerala, India. Questionnaire was distributed among a batch of 120 second year MBBS students after one of the pharmacology lecture session. Attitude and Practices related questions were assessed using Likert scale. Data was entered in excel and analysed using descriptive statistics of SPSS to generate frequency and percentage.Results: 91.6% (110) were considered valid for analysis. Mean age was 21±1 years. Students had fair knowledge regarding antibiotics usage and resistance with mean correct response 79.72±25.37%. Mean correct responses of attitude and practices related questions were found to be 55.95±25.63% and 64±13.79% respectively.Conclusions: Most of the students were aware of the antibiotic resistance and its consequences. However, their attitude and practices were found to be a matter of great concern. An educational intervention can be introduced to bring about behaviour changes regarding rational antibiotics prescribing among them

Post-operative atrial fibrillation in off pump coronary artery bypass graft: association with medication

Background: Post-operative atrial fibrillation is a common post-operative complication and has significant morbidity and mortality. This study was done with an objective to determine the association of various medication use in patients undergoing coronary artery bypass graft (CABG) with post-operative atrial fibrillation (POAF).Methods: This was a prospective observational study done in the department of cardiovascular and thoracic surgery of GMC Kottayam from December 2019 to December 2020 after obtaining institutional review board clearance. A sample size of 334 was fixed and patients undergoing off pump (OP) CABG were consecutively recruited in the study. The association of intraoperative and postoperative medication use with occurrence of POAF were analysed using the univariate analysis with a p<0.05 using the SPSS 16 software.Results: Peri-operative inotrope use was found to be significantly associated with post operative atrial fibrillation odds ratio 1.08 (95% CI 1.02-1.13). We could not find any association with preoperative use of beta blockers/agonist, antidiabetics, levothyroxine, ACE inhibitors or antiplatelet drugs. All the patients 60 (18%) who developed POAF were given amiodarone as per protocol.Conclusions: Perioperative inotrope use was found to have significant association with the development of post operative atrial fibrillation following OPCABG. More multi-institutional studies with determination of association with individual drugs and doses with POAF need to be conducted in future

Knowledge, attitude and practices of antibiotic usage and resistance among the second year MBBS Students

Background: Social aspect of antibiotic management forms a significant way to overcome the rapidly intensifying problem of antibiotic resistance. Knowledge helps in spreading awareness and understanding while attitude and practices influences health related behaviour. Medical students should not only be made aware of the current emerging health issues but also be directed towards rational antibiotics prescribing behaviour as future medical practitioners. Therefore, present study was undertaken to assess the existing knowledge, attitude and practices (KAP) related to antibiotic usage and resistance among second year (fourth semester) MBBS students.Methods: This was a cross-sectional, questionnaire based study conducted in department of pharmacology of a government medical college in Kerala, India. Questionnaire was distributed among a batch of 120 second year MBBS students after one of the pharmacology lecture session. Attitude and Practices related questions were assessed using Likert scale. Data was entered in excel and analysed using descriptive statistics of SPSS to generate frequency and percentage.Results: 91.6% (110) were considered valid for analysis. Mean age was 21±1 years. Students had fair knowledge regarding antibiotics usage and resistance with mean correct response 79.72±25.37%. Mean correct responses of attitude and practices related questions were found to be 55.95±25.63% and 64±13.79% respectively.Conclusions: Most of the students were aware of the antibiotic resistance and its consequences. However, their attitude and practices were found to be a matter of great concern. An educational intervention can be introduced to bring about behaviour changes regarding rational antibiotics prescribing among them

Data from: Critical analysis of forest degradation in the southern Eastern Ghats of India: comparison of satellite imagery and soil quality index

India has one of the largest assemblages of tropical biodiversity, with its unique floristic composition of endemic species. However, current forest cover assessment is performed via satellite-based forest surveys, which have many limitations. The present study, which was performed in the Eastern Ghats, analysed the satellite-based inventory provided by forest surveys and inferred from the results that this process no longer provides adequate information for quantifying forest degradation in an empirical manner. The study analysed 21 soil properties and generated a forest soil quality index of the Eastern Ghats, using principal component analysis. Using matrix modules and geospatial technology, we compared the forest degradation status calculated from satellite-based forest surveys with the degradation status calculated from the forest soil quality index. The Forest Survey of India classified about 1.8% of the Eastern Ghats’ total area as degraded forests and the remainder (98.2%) as open, dense, and very dense forests, whereas the soil quality index results found that about 42.4% of the total area is degraded, with the remainder (57.6%) being non-degraded. Our ground truth verification analyses indicate that the forest soil quality index along with the forest cover density data from the Forest Survey of India are ideal tools for evaluating forest degradation

Data from: Critical analysis of forest degradation in the southern Eastern Ghats of India: comparison of satellite imagery and soil quality index

India has one of the largest assemblages of tropical biodiversity, with its unique floristic composition of endemic species. However, current forest cover assessment is performed via satellite-based forest surveys, which have many limitations. The present study, which was performed in the Eastern Ghats, analysed the satellite-based inventory provided by forest surveys and inferred from the results that this process no longer provides adequate information for quantifying forest degradation in an empirical manner. The study analysed 21 soil properties and generated a forest soil quality index of the Eastern Ghats, using principal component analysis. Using matrix modules and geospatial technology, we compared the forest degradation status calculated from satellite-based forest surveys with the degradation status calculated from the forest soil quality index. The Forest Survey of India classified about 1.8% of the Eastern Ghats’ total area as degraded forests and the remainder (98.2%) as open, dense, and very dense forests, whereas the soil quality index results found that about 42.4% of the total area is degraded, with the remainder (57.6%) being non-degraded. Our ground truth verification analyses indicate that the forest soil quality index along with the forest cover density data from the Forest Survey of India are ideal tools for evaluating forest degradation

Comparative study of the toxicity of 5-fluorouracil-adriamycin-cyclophosphamide versus adriamycin-cyclophosphamide followed by paclitaxel in carcinoma breast

Context: When cure is possible treatment should be undertaken despite life-threatening toxicities. Fluorouracil-Adriamycin-Cyclophosphamide (FAC) and Adriamycin-Cyclophosphamide (AC-P) are two popular regimens used in the treatment of carcinoma breast and the data regarding the toxicity profile of the AC-P regimen is scarce in the South Indian population. Aims: To study the severity of different types of toxicities seen in patients on FAC and AC-P regimens, to grade the toxicity according to the World Health Organization (WHO) toxicity grading, and to compare the same. Settings and Design: A prospective observational study, with 50 patients in each regimen, was conducted in the Department of Radiotherapy between February 2007 and July 2008. Materials and Methods: The high risk patients received the AC-P regimen and the rest received the FAC regimen. The toxicities developed were graded according to the WHO guidelines. Statistical Analysis Used: The data was analyzed using the chi square test in SPSS 16. Results: Anemia, hyperpigmentation, stomatitis, and diarrhea were significantly high (P &lt; 0.05) in patients receiving the FAC regimen, whereas, leukopenia, myalgia, arthralgia and peripheral neuropathy were significantly high (P &lt;0.05) in patients receiving the AC-P regimen. The Karnofsky performance status was higher in patients receiving the AC-P regimen. Conclusions: Although both the regimens had different toxicity profiles the quality of life was better for patients on the AC-P regimen

Comparative study of the toxicity of 5-fluorouracil-adriamycin-cyclophosphamide versus adriamycin-cyclophosphamide followed by paclitaxel in carcinoma breast

Context: When cure is possible treatment should be undertaken despite life-threatening toxicities. Fluorouracil-Adriamycin-Cyclophosphamide (FAC) and Adriamycin-Cyclophosphamide (AC-P) are two popular regimens used in the treatment of carcinoma breast and the data regarding the toxicity profile of the AC-P regimen is scarce in the South Indian population. Aims: To study the severity of different types of toxicities seen in patients on FAC and AC-P regimens, to grade the toxicity according to the World Health Organization (WHO) toxicity grading, and to compare the same. Settings and Design: A prospective observational study, with 50 patients in each regimen, was conducted in the Department of Radiotherapy between February 2007 and July 2008. Materials and Methods: The high risk patients received the AC-P regimen and the rest received the FAC regimen. The toxicities developed were graded according to the WHO guidelines. Statistical Analysis Used: The data was analyzed using the chi square test in SPSS 16. Results: Anemia, hyperpigmentation, stomatitis, and diarrhea were significantly high (P < 0.05) in patients receiving the FAC regimen, whereas, leukopenia, myalgia, arthralgia and peripheral neuropathy were significantly high (P <0.05) in patients receiving the AC-P regimen. The Karnofsky performance status was higher in patients receiving the AC-P regimen. Conclusions: Although both the regimens had different toxicity profiles the quality of life was better for patients on the AC-P regimen

Soil Quality Index Data

Soil Parameters used to prepare soil quality inde

Forest soil quality index of the Eastern Ghats.

<p>Forest soil quality index of the Eastern Ghats.</p

Study area—Eastern Ghats of Southern India.

<p>Study area—Eastern Ghats of Southern India.</p