62 research outputs found
Učinci različitih aspekata koordinacije na način borenja i razinu sportske vještine kadetskih judo natjecatelja
The primary aim of this study was to determine the relationship between certain aspects of coordination, the time course of a bout and sport-related skill levels in cadet judoists. The study evaluated eight judokas with high sport skill levels. Based on the analysis of tournament matches (N=66), the authors determined the activity, effectiveness of actions and the level of achievement. Ten aspects of coordination were assessed by 28 indices. It was found that a high level of adaptive ability was a prerequisite for high levels of activity during the phase I of a bout. Shorter durations of complex reaction time were correlated with higher effectiveness in both the phase I and throughout a bout. High level of visual-motor coordination was correlated with high effectiveness and its increase during the phase II of a bout. Certain aspects of coordination seem to be necessary components of the technical and tactical coaching of cadets. However, they do not correlate directly with the level of achievement.Primarni cilj ovog istraživanja bio je utvrditi povezanost između pojedinih aspekata koordinacije, tijeka borbe i razine specifičnih motoričkih znanja u judaša kadetskog uzrasta. U istraživanju je testirano osam tehnički visokokvalitetnih judaša. Na temelju analize turnirskih borbi (N=66), autori su utvrdili aktivnost, učinkovitost akcija te razinu uspjeha sportaša. Deset aspekata koordinacije bilo je procijenjeno pomoću 28 pokazatelja. Utvrđeno je da je visoka razina sposobnosti adaptacije preduvjet za visoku razinu aktivnosti tijekom prve polovice judo borbe. Kraće vrijeme kompleksne reakcije bilo je u korelaciji s višom razinom učinkovitosti u prvom dijelu borbe, ali i tijekom cijele borbe. Visoka razina vizualno-motoričke koordinacije predstavlja preduvjet za visoku razinu učinkovitosti u borbi, a razina koordinacije povećavala se tijekom drugog dijela borbe. Čini se da su određeni aspekti koordinacije komponente potrebne za tehničko-taktičko usavršavanje kadeta. Ipak, aspekti koordinacije nisu izravno povezani s razinom uspjeha na natjecanju
Apremilast, an oral phosphodiesterase 4 inhibitor, in patients with psoriatic arthritis and current skin involvement: a phase III, randomised, controlled trial (PALACE 3)
OBJECTIVE: To evaluate apremilast treatment in patients with active psoriatic arthritis, including current skin involvement, despite prior therapy with conventional disease-modifying antirheumatic drugs and/or biologic agents.
METHODS: Patients (N=505) were randomised (1:1:1) to placebo, apremilast 20 mg twice daily, or apremilast 30 mg twice daily. Rescue therapy with apremilast was designated at week 16 for placebo patients not achieving 20% improvement in swollen and tender joint counts. At week 24, the remaining placebo patients were then randomised to apremilast 20 mg twice daily or 30 mg twice daily. The efficacy and safety of apremilast were assessed over 52 weeks.
RESULTS: At week 16, significantly more patients receiving apremilast 20 mg twice daily (28%) and 30 mg twice daily (41%) achieved 20% improvement in American College of Rheumatology response criteria versus placebo (18%; p=0.0295 and p \u3c 0.0001, respectively), and mean decrease in the Health Assessment Questionnaire-Disability Index score was significantly greater with apremilast 30 mg twice daily (-0.20) versus placebo (-0.07; p=0.0073). In patients with baseline psoriasis body surface area involvement \u3e /=3%, significantly more apremilast 30 mg twice daily patients achieved 50% reduction from baseline Psoriasis Area and Severity Index score (41%) versus placebo (24%; p=0.0098) at week 16. At week 52, observed improvements in these measures demonstrated sustained response with continued apremilast treatment. Most adverse events were mild to moderate in severity; the most common were diarrhoea, nausea, headache and upper respiratory tract infection.
CONCLUSIONS: Apremilast demonstrated clinically meaningful improvements in psoriatic arthritis and psoriasis at week 16; sustained improvements were seen with continued treatment through 52 weeks. Apremilast was generally well tolerated and demonstrated an acceptable safety profile.
TRIAL REGISTRATION NUMBER: NCT01212770
Growth, body composition, and cardiovascular and nutritional risk of 5- to 10-y-old children consuming vegetarian, vegan, or omnivore diets.
BACKGROUND: Plant-based diets (PBDs) are increasingly recommended for human and planetary health. However, comprehensive evidence on the health effects of PBDs in children remains incomplete, particularly in vegans. OBJECTIVES: To quantify differences in body composition, cardiovascular risk, and micronutrient status of vegetarian and vegan children relative to omnivores and to estimate prevalence of abnormal micronutrient and cholesterol status in each group. METHODS: In a cross-sectional study, Polish children aged 5-10 y (63 vegetarian, 52 vegan, 72 matched omnivores) were assessed using anthropometry, deuterium dilution, DXA, and carotid ultrasound. Fasting blood samples, dietary intake, and accelerometry data were collected. RESULTS: All results are reported relative to omnivores. Vegetarians had lower gluteofemoral adiposity but similar total fat and lean mass. Vegans had lower fat indices in all regions but similar lean mass. Both groups had lower bone mineral content (BMC). The difference for vegetarians attenuated after accounting for body size but remained in vegans (total body minus the head: -3.7%; 95% CI: -7.0, -0.4; lumbar spine: -5.6%; 95% CI: -10.6, -0.5). Vegetarians had lower total cholesterol, HDL, and serum B-12 and 25-hydroxyvitamin D [25(OH)D] without supplementation but higher glucose, VLDL, and triglycerides. Vegans were shorter and had lower total LDL (-24 mg/dL; 95% CI: -35.2, -12.9) and HDL (-12.2 mg/dL; 95% CI: -17.3, -7.1), high-sensitivity C-reactive protein, iron status, and serum B-12 (-217.6 pmol/L; 95% CI: -305.7, -129.5) and 25(OH)D without supplementation but higher homocysteine and mean corpuscular volume. Vitamin B-12 deficiency, iron-deficiency anemia, low ferritin, and low HDL were more prevalent in vegans, who also had the lowest prevalence of high LDL. Supplementation resolved low B-12 and 25(OH)D concentrations. CONCLUSIONS: Vegan diets were associated with a healthier cardiovascular risk profile but also with increased risk of nutritional deficiencies and lower BMC and height. Vegetarians showed less pronounced nutritional deficiencies but, unexpectedly, a less favorable cardiometabolic risk profile. Further research may help maximize the benefits of PBDs in children
Vibration trauma as a causative factor of internal carotid artery dissection
Vibration trauma serves as a potential yet not recognized in large clinical series risk factor of cervical artery dissection. We present case report of a young male patient who developed internal carotid artery dissection as a result of prolonged drilling
TEORIA WZMOCNIENIA JEDNOFOLIOWEGO DETEKTORA Z GAZOWYM POWIELANIEM ELEKTRONÓW
Gain prediction theory of single foil Gas Electron Multiplier detector was developed. Gas electron multiplier (GEM) detector with single foil was developed. Soft X-ray spectra with an energy of 5.9 keV emitted by the isotope Fe-55 were measured. On this basis, the dependence of gain and energy resolution from the detector voltage was determined. The simple theory of gain dependence on various detector parameters was developed. Preliminary results of the study confirmed the potential usefulness of the GEM detector as a substitute for the multiwire proportional chamber.Opracowano teorię wzmocnienia jednofoliowego detektora z gazowym powielaniem elektronów. Opracowano detektor z gazowym powielaniem elektronów z pojedynczą folią. Zmierzono widmo miękkiego promieniowania X, o energii 5,9 keV, emitowanego przez izotop Fe-55. Na tej podstawie wyznaczono zależność wzmocnienia i energetycznej zdolności rozdzielczej od napięcia zasilającego detektor. Opracowano prosta teorią zależności wzmocnienia od różnych parametrów detektora. Wstępne rezultaty badań potwierdzają potencjalną przydatność detektora GEM jako substytutu wielodrutowej komory proporcjonalnej
Współpraca Instytutu Łączności z wybranymi partnerami zagranicznymi, Telekomunikacja i Techniki Informacyjne, 2018, nr 1-2
Artykuł przedstawia pokrótce historię międzynarodowej współpracy Instytutu Łączności – Państwowego Instytutu Badawczego (IŁ) w wybranych dziedzinach, ze szczególnym uwzględnieniem najistotniejszych międzynarodowych konferencji, których był inicjatorem i organizatorem oraz w zakresie współpracy w ramach najważniejszych organizacji międzynarodowych (ITU, CEPT, IEC, IALA-IMO, ETSI, URSI, IEEE-EMCS, ICTP, OWŁ/RWPG)
Historia książki na terenach pogranicza i jej rola w kształtowaniu społeczeństw wielokulturowych : materiały z polsko-niemieckiej konferencji bibliotekarzy, Zielona Góra, 21-22 kwietnia 2005 = Zur Geschichte des Buches in der Grenzregion und dessen Rolle in der Bildung der multikulturellen Gesellschaften : Materialien aus der deutsch-polnischen Konferenz der Bibliothekaren und Bibliothekarinnen, Zielona Góra, den 21-22 April 2005
Zrealizowano przy pomocy finansowej Unii Europejskiej
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