Victor or victim? Foregrounding the independent escort experience outside of the polarised debate

The sex worker as a sociocultural ‘phenomenon’ occupies a liminal space, simultaneously absent from sociopolitical acceptability yet ever present in often inflammatory, ‘condemn/celebrate’ discourses. In this paper we aim to contribute to a destabilising of the dichotomisation of these representations by referring to the lived experience of independent escorts. In addition we attempt to contextualize the sex worker in consumer capitalism through which notions of choice and exploitation, that arise from both sides of the ‘condemn’/’celebrate’ debate, are rendered oblique. We draw upon the author’s own experience of being an escort as well as accounts from a popular escort internet forum1 to illustrate the issues escorts share with women as a wider social demographic, including violence and abuse, appearance pressures, and economic hardship. By situating escorting as a form of self-employment labour, within the practical reality of neoliberal, consumer capitalism, we aid in the nuancing of the debate, foregrounding the escort experience over prior, moral ideologies. We also promote the merging of the academic debate surrounding the sex work industry, with the grassroots debate that forum member escorts have on a daily basis. We conclude it is important to demystify and destigmatise escorts so they are not regarded as 'victims or victors' or other grotesque parodies, but a real, diverse people and members of a labour force

Debye mass and heavy quark potential in a PNJL quark plasma

We calculate the Debye mass for the screening of the heavy quark potential in a plasma of massless quarks coupled to the temporal gluon background governed by the Polyakov loop potential within the PNJL model in RPA approximation. We give a physical motivation for a recent phenomenological fit of lattice data by applying the calculated Debye mass with its suppression in the confined phase due to the Polyakov-loop to a description of the temperature dependence of the singlet free energy for QCD with a heavy quark pair at infinite separation. We compare the result to lattice data.Comment: 6 pages, 1 figure, contribution to Proceedings of the 6th International Conference on "Critical Point and Onset of Deconfinement", to appear in Phys. At. Nucl., vol. 7

Preliminary results from breeding experiments with Finnsheep in Poland

Polish Lowland (PL) ewes were mated to Finnsheep x East Friesian (EF) F1 rams to create a synthetic dam line (66), and to Polish Heath x EF F1 rams to create another synthetic dam line (77). Performance of both groups were recorded and compared to purebred PL (88). The numbers of animals in the composite lines were too small for statistical analyses and conclusive results. Contrary to expectations line 77 excelled line 88 in lambing rate by 3 %, while line 66 was inferior to it. In litter size, both composite lines slightly excelled line 88. Line 66 excelled line 88 in lamb survival, while line 77 was a little inferior to it. In fleece weights, line 66 was equal with line 88, but line 77 lagged 24 % behind. Both of the composite lines excelled line 88 in daily gain by 10 %, being rather similar to each other

The olive biophenols oleuropein and hydroxytyrosol selectively reduce proliferation, influence the cell cycle, and induce apoptosis in pancreatic cancer cells

Current chemotherapy drugs for pancreatic cancer only offer an increase in survival of up to six months. Additionally, they are highly toxic to normal tissues, drastically affecting the quality of life of patients. Therefore, the search for novel agents, which induce apoptosis in cancer cells while displaying limited toxicity towards normal cells, is paramount. The olive biophenols, oleuropein, hydroxytyrosol and tyrosol, have displayed cytotoxicity towards cancer cells without affecting non-tumorigenic cells in cancers of the breast and prostate. However, their activity in pancreatic cancer has not been investigated. Therefore, the aim of this study was to determine the anti-pancreatic cancer potential of oleuropein, hydroxytyrosol and tyrosol. Pancreatic cancer cells (MIA PaCa-2, BxPC-3, and CFPAC-1) and non-tumorigenic pancreas cells (HPDE) were treated with oleuropein, hydroxytyrosol and tyrosol to determine their effect on cell viability. Oleuropein displayed selective toxicity towards MIA PaCa-2 cells and hydroxytyrosol towards MIA PaCa-2 and HPDE cells. Subsequent analysis of Bcl-2 family proteins and caspase 3/7 activation determined that oleuropein and hydroxytyrosol induced apoptosis in MIA PaCa-2 cells, while oleuropein displayed a protective effect on HPDE cells. Gene expression analysis revealed putative mechanisms of action, which suggested that c-Jun and c-Fos are involved in oleuropein and hydroxytyrosol induced apoptosis of MIA PaCa-2 cells

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Copyright © 2002, BMJJanusz Jankowski, Roger Jones, Brendan Delaney and John Den

A New 5 Flavour NLO Analysis and Parametrizations of Parton Distributions of the Real Photon

New, radiatively generated, NLO quark (u,d,s,c,b) and gluon densities in a real, unpolarized photon are presented. We perform three global fits, based on the NLO DGLAP evolution equations for Q^2>1 GeV^2, to all the available structure function F_2^gamma(x,Q^2) data. As in our previous LO analysis we utilize two theoretical approaches. Two models, denoted as FFNS_{CJK}1 & 2 NLO, adopt the so-called Fixed Flavour-Number Scheme for calculation of the heavy-quark contributions to F_2^gamma(x,Q^2), the CJK NLO model applies the ACOT(chi) scheme. We examine the results of our fits by a comparison with the LEP data for the Q^2 dependence of the F_2^gamma, averaged over various x-regions, and the F_2,c^gamma. Grid parametrizations of the parton densities for all fits are provided.Comment: 49 pages, 27 postscript figures; FORTRAN programs available at http://www.fuw.edu.pl/~pjank/param.htm

Ultrabroadband Nonlinear Optics in Nanophotonic Periodically Poled Lithium Niobate Waveguides

Quasi-phasematched interactions in waveguides with quadratic nonlinearities enable highly efficient nonlinear frequency conversion. In this article, we demonstrate the first generation of devices that combine the dispersion-engineering available in nanophotonic waveguides with quasi-phasematched nonlinear interactions available in periodically poled lithium niobate (PPLN). This combination enables quasi-static interactions of femtosecond pulses, reducing the pulse energy requirements by several orders of magnitude, from picojoules to femtojoules. We experimentally demonstrate two effects associated with second harmonic generation. First, we observe efficient quasi-phasematched second harmonic generation with <100 fJ of pulse energy. Second, in the limit of strong phase-mismatch, we observe spectral broadening of both harmonics with as little as 2-pJ of pulse energy. These results lay a foundation for a new class of nonlinear devices, in which co-engineering of dispersion with quasi-phasematching enables efficient nonlinear optics at the femtojoule level

Proteomic-biostatistic integrated approach for finding the underlying molecular determinants of hypertension in human plasma

Despite advancements in lowering blood pressure, the best approach to lower it remains controversial because of the lack of information on the molecular basis of hypertension. We, therefore, performed plasma proteomics of plasma from patients with hypertension to identify molecular determinants detectable in these subjects but not in controls and vice versa. Plasma samples from hypertensive subjects (cases; n=118) and controls (n=85) from the InGenious HyperCare cohort were used for this study and performed mass spectrometric analysis. Using biostatistical methods, plasma peptides specific for hypertension were identified, and a model was developed using least absolute shrinkage and selection operator logistic regression. The underlying peptides were identified and sequenced off-line using matrix-assisted laser desorption ionization orbitrap mass spectrometry. By comparison of the molecular composition of the plasma samples, 27 molecular determinants were identified differently expressed in cases from controls. Seventy percent of the molecular determinants selected were found to occur less likely in hypertensive patients. In cross-validation, the overall R(2) was 0.434, and the area under the curve was 0.891 with 95% confidence interval 0.8482 to 0.9349, P&lt;0.0001. The mean values of the cross-validated proteomic score of normotensive and hypertensive patients were found to be -2.007±0.3568 and 3.383±0.2643, respectively, P&lt;0.0001. The molecular determinants were successfully identified, and the proteomic model developed shows an excellent discriminatory ability between hypertensives and normotensives. The identified molecular determinants may be the starting point for further studies to clarify the molecular causes of hypertension