Effect of enzyme-aided juice production on the extractability and profile of berry anthocyanins

These experiments showed that the anthocyanin yield increased significantly in certain enzyme-aided treatments as compared to control

Fermion pairing with spin-density imbalance in an optical lattice

We consider pairing in a two- component atomic Fermi gas, in a three- dimensional optical lattice, when the components have unequal densities, i. e. the gas is polarized. We show that a superfluid where the translational symmetry is broken by a finite Cooper pair momentum, namely a Fulde Ferrel - Larkin - Ovchinnikov ( FFLO)- type state, minimizes the Helmholtz free energy of the system. We demonstrate that such a state is clearly visible in the observable momentum distribution of the atoms, and analyse the dependence of the order parameter and the momentum distribution on the filling fraction and the interaction strength.We consider pairing in a two- component atomic Fermi gas, in a three- dimensional optical lattice, when the components have unequal densities, i. e. the gas is polarized. We show that a superfluid where the translational symmetry is broken by a finite Cooper pair momentum, namely a Fulde Ferrel - Larkin - Ovchinnikov ( FFLO)- type state, minimizes the Helmholtz free energy of the system. We demonstrate that such a state is clearly visible in the observable momentum distribution of the atoms, and analyse the dependence of the order parameter and the momentum distribution on the filling fraction and the interaction strength.We consider pairing in a two- component atomic Fermi gas, in a three- dimensional optical lattice, when the components have unequal densities, i. e. the gas is polarized. We show that a superfluid where the translational symmetry is broken by a finite Cooper pair momentum, namely a Fulde Ferrel - Larkin - Ovchinnikov ( FFLO)- type state, minimizes the Helmholtz free energy of the system. We demonstrate that such a state is clearly visible in the observable momentum distribution of the atoms, and analyse the dependence of the order parameter and the momentum distribution on the filling fraction and the interaction strength.Peer reviewe

Longitudinal trends of per- and polyfluoroalkyl substances in children's serum

Studies suggest negative health impacts from early life exposure to per- and polyfluoroalkyl substances (PFASs). However, information on longitudinal exposure to PFASs during childhood is scarce for background-exposed individuals. This study sought to fill this gap by investigating children's longitudinal exposure trends through measurement of PFAS serum concentrations and calculation of body burdens (mu g, total in body). Blood of 54 Finnish children was sampled 2005-2015 and analyzed for 20 PFASs at 1, 6 and 10.5 years of age. The body burden was calculated by multiplying the serum concentration by the volume of distribution and the bodyweight for each individual. Associations between serum concentrations or body burdens and parameters, such as sex, breastfeeding duration, body mass index as well as indoor dust and air PFAS concentrations, were evaluated. Serum concentrations of perfluorooctane sulfonic acid (PFOS), perfluorooctanoic acid (PFOA), perfluorononanoic acid (PFNA) and perfluorohexane sulfonic acid (PFHxS) decreased significantly (p <0.001) with age. In contrast to serum concentrations, body burdens stayed unchanged or even increased significantly (p <0.05), except for PFOA in female children. Breastfeeding duration was positively correlated (p <0.001) with serum concentrations of PFHxS, PFOS, PFOA and PFNA at 1 year of age. Some associations were found at 10.5 years with sex and indoor PFAS concentrations. Observations of longitudinal decreasing trends of serum concentrations can be misleading for understanding exposure levels from external media during childhood, as the serum concentration is influenced by parallel temporal changes and growth dilution. Body burdens account for growth dilution and thus better reflect differences in early-life to adolescence exposure than serum concentrations.Peer reviewe

Perfluoroalkyl acids and their precursors in floor dust of children's bedrooms - Implications for indoor exposure

We analysed floor dust samples from 65 children's bedrooms in Finland collected in 2014/2015 for 62 different per- and polyfluoroalkyl substances (PFASs) with a simple and highly efficient method. Validation results from the analysis of standard reference material (SRM) 2585 were in good agreement with literature data, while 24 PFASs were quantified for the first time. In the dust samples from children's bedrooms, five perfluoroalkyl carboxylic acids (PFCAs) and perfluorooctane sulfonic acid (PFOS) were detected in more than half of the samples with the highest median concentration of 5.26 ng/g for perfluorooctanoic acid (PFOA). However, the dust samples were dominated by polyfluoroalkyl phosphoric acid esters (PAPs) and fluorotelomer alcohols (FTOHs) (highest medians: 53.9 ng/g for 6:2 diPAP and 45.7 ng/g for 8:2 FTOH). Several significant and strong correlations (up to p = 0.95) were found among different PFASs in dust as well as between PFASs in dust and air samples (previously published) from the same rooms. The logarithm of dust to air concentrations (log K-dust/air) plotted against the logarithm of the octanol-air partition coefficient (log K-oa) resulted in a significant linear regression line with R-2 > 0.88. Higher dust levels of PFOS were detected in rooms with plastic flooring material in comparison to wood (p <0.05). Total estimated daily intakes via dust (EDIdust) and air (EDIair) of perfluoroalkyl acids (PFAA), including biotransformation of precursors to PFAAs, were calculated for 10.5-year-old children. The total EDIdust, for PFOA and PFOS were estimated to be 0.007 ng/kg bw/day and 0.006 ng/kg bw/day, respectively, in an intermediate exposure scenario. The sum of the total EDIs for all PFAAs was slightly higher for dust than air (0.027 and 0.019 ng/kg bw/day). Precursor biotransformation was generally important for total PFOS intake, while for the PFCAs, FTOH biotransformation was estimated to be important for air, but not for dust exposure.Peer reviewe

FFLO state in 1-, 2- and 3-dimensional optical lattices combined with a non-uniform background potential

We study the phase diagram of an imbalanced two-component Fermi gas in optical lattices of 1-3 dimensions (1D-3D), considering the possibilities of the Fulde-Ferrel-Larkin-Ovchinnikov (FFLO), Sarma/breached pair, BCS and normal states as well as phase separation, at finite and zero temperatures. In particular, phase diagrams with respect to average chemical potential and the chemical potential difference of the two components are considered, because this gives the essential information about the shell structures of phases that will occur in the presence of an additional (harmonic) confinement. These phase diagrams in 1D, 2D and 3D show in a striking way the effect of Van Hove singularities on the FFLO state. Although we focus on population imbalanced gases, the results are relevant also for the (effective) mass imbalanced case. We demonstrate by LDA calculations that various shell structures such as normal-FFLO-BCS-FFLO-normal, or FFLO-normal, are possible in presence of a background harmonic trap. The phases are reflected in noise correlations: especially in 1D the unpaired atoms leave a clear signature of the FFLO state as a zero-correlation area ('breach') within the Fermi sea. This strong signature occurs both for a 1D lattice as well as for a 1D continuum. We also discuss the effect of Hartree energies and the Gorkov correction on the phase diagrams.We study the phase diagram of an imbalanced two-component Fermi gas in optical lattices of 1-3 dimensions (1D-3D), considering the possibilities of the Fulde-Ferrel-Larkin-Ovchinnikov (FFLO), Sarma/breached pair, BCS and normal states as well as phase separation, at finite and zero temperatures. In particular, phase diagrams with respect to average chemical potential and the chemical potential difference of the two components are considered, because this gives the essential information about the shell structures of phases that will occur in the presence of an additional (harmonic) confinement. These phase diagrams in 1D, 2D and 3D show in a striking way the effect of Van Hove singularities on the FFLO state. Although we focus on population imbalanced gases, the results are relevant also for the (effective) mass imbalanced case. We demonstrate by LDA calculations that various shell structures such as normal-FFLO-BCS-FFLO-normal, or FFLO-normal, are possible in presence of a background harmonic trap. The phases are reflected in noise correlations: especially in 1D the unpaired atoms leave a clear signature of the FFLO state as a zero-correlation area ('breach') within the Fermi sea. This strong signature occurs both for a 1D lattice as well as for a 1D continuum. We also discuss the effect of Hartree energies and the Gorkov correction on the phase diagrams.We study the phase diagram of an imbalanced two-component Fermi gas in optical lattices of 1-3 dimensions (1D-3D), considering the possibilities of the Fulde-Ferrel-Larkin-Ovchinnikov (FFLO), Sarma/breached pair, BCS and normal states as well as phase separation, at finite and zero temperatures. In particular, phase diagrams with respect to average chemical potential and the chemical potential difference of the two components are considered, because this gives the essential information about the shell structures of phases that will occur in the presence of an additional (harmonic) confinement. These phase diagrams in 1D, 2D and 3D show in a striking way the effect of Van Hove singularities on the FFLO state. Although we focus on population imbalanced gases, the results are relevant also for the (effective) mass imbalanced case. We demonstrate by LDA calculations that various shell structures such as normal-FFLO-BCS-FFLO-normal, or FFLO-normal, are possible in presence of a background harmonic trap. The phases are reflected in noise correlations: especially in 1D the unpaired atoms leave a clear signature of the FFLO state as a zero-correlation area ('breach') within the Fermi sea. This strong signature occurs both for a 1D lattice as well as for a 1D continuum. We also discuss the effect of Hartree energies and the Gorkov correction on the phase diagrams.Peer reviewe

Perfluoroalkyl acids and their precursors in indoor air sampled in children's bedrooms

The contamination levels and patterns of perfluoroallcyl acids (PFAAs) and their precursors in indoor air of children's bedrooms in Finland, Northern Europe, were investigated. Our study is among the most comprehensive indoor air monitoring studies (n = 57) and to our knowledge the first one to analyse air in children's bedrooms for PFASs (17 PFAAs and 9 precursors, including two acrylates, 6:2 FTAC and 6:2 FTMAC). The most frequently detected compound was 8:2 fluorotelomer alcohol (8:2 FTOH) with the highest median concentration (3570 pg/m(3)). FTOH concentrations were generally similar to previous studies, indicating that in 2014/2015 the impact of the industrial transition had been minor on FTOH levels in indoor air. However, in contrast to earlier studies (with one exception), median concentrations of 6:2 FTOH were higher than 10:2 FTOH. The C8 PFAAs are still the most abundant acids, even though they have now been phased out by major manufacturers. The mean concentrations of FOSE/As, especially MeFOSE (89.9 pg/m(3)), were at least an order of magnitude lower compared to previous studies. Collectively the comparison of FTOHs, PFAAs and FOSE/FOSAs with previous studies indicates that indoor air levels of PFASs display a time lag to changes in production of several years. This is the first indoor air study investigating 6:2 FTMAC, which was frequently detected (58%) and displayed some of the highest maximum concentrations (13 000 pg/m(3)). There were several statistically significant correlations between particular house and room characteristics and PFAS concentrations, most interestingly higher EtFOSE air concentrations in rooms with plastic floors compared to wood or laminate. (C) 2016 Published by Elsevier Ltd.Peer reviewe

Lifetime antipsychotic medication and cognitive performance in schizophrenia at age 43 years in a general population birth cohort

This naturalistic study analysed the association between cumulative lifetime antipsychotic dose and cognition in schizophrenia after an average of 16.5 years of illness. Sixty participants with schizophrenia and 191 controls from the Northern Finland Birth Cohort 1966 were assessed at age 43 years with a neurocognitive test battery. Cumulative lifetime antipsychotic dose-years were collected from medical records and interviews. The association between antipsychotic dose-years and a cognitive composite score based on principal component analysis was analysed using linear regression. Higher lifetime antipsychotic dose-years were significantly associated with poorer cognitive composite score, when adjusted for gender, onset age and lifetime hospital treatment days. The effects of typical and atypical antipsychotics did not differ. This is the first report of an association between cumulative lifetime antipsychotic dose and global cognition in midlife schizophrenia. Based on these data, higher lifetime antipsychotic dose-years may be associated with poorer cognitive performance at age 43 years. Potential biases related to the naturalistic design may partly explain the results; nonetheless, it is possible that large antipsychotic doses harm cognition in schizophrenia in the long-term.Peer reviewe