Work and non-work adjustments of public sector expatriates

Version of RecordResearch on public sector expatriates is not very common, despite their increasing numbers. This is lamentable, since our much more advanced knowledge about private sector expatriates may be less applicable to their public sector counterparts. To rectify this deficiency, U.S. Department of Defense administrators assigned to U.S. embassies worldwide were targeted for this study. Results indicated that, in contrast to recent studies of private sector expatriates, stress experienced by the respondents outside work may only have a limited cross-domain effect on the level of stress in the work place. Interaction adjustment had a positive association with work adjustment but general adjustment had no relationship with the adjustment to work. Additionally, the extent of self-efficacy of the public sector expatriates was not associated with work adjustment, neither directly or indirectly. Implications of these findings are discussed in detail.Fenner, C. R. & Selmer, J. (2007, October). Work and non-work adjustments of public sector expatriates. Presented at the Academy of International Business U.S. Northeast Chapter Regional Meeting, Portsmouth, New Hampshire. Retrieved from http://academicarchive.snhu.ed

Proton pump inhibitor use and risk of adverse cardiovascular events in aspirin treated patients with first time myocardial infarction: nationwide propensity score matched study

Objective To examine the effect of proton pump inhibitors on adverse cardiovascular events in aspirin treated patients with first time myocardial infarction

Translation initiation from the ribosomal A site or the P site, dependent on the conformation of RNA pseudoknot I in dicistrovirus RNAs

available in PMC 2010 July 31.Translation initiation of the second ORF of insect dicistrovirus RNA depends on an internal ribosomal entry site (IRES) in its intergenic region (IGR) and is exceptional in using a codon other than AUG and in not using the canonical initiator methionine tRNA. Studies in vitro suggest that pseudoknot I (PKI) immediately preceding the initiation codon occupies the ribosomal P site and that an elongator tRNA initiates translation from the ribosomal A site. Using dicistronic reporters carrying mutations in the initiation codon of the second ORF and mutant elongator or initiator tRNAs capable of reading these codons, we provide direct evidence for initiation from the A site in mammalian cells and, under certain conditions, also from the P site. Initiation from the A but not the P site requires PKI. Thus, PKI structure may be dynamic, and optimal IGR IRES-mediated translation of dicistroviral RNAs may require trans-acting factors to stabilize PKI.National Institutes of Health (U.S.) (grant GM17151)Japan. Ministry of Education, Culture, Sports, Science and Technology (Grants-In-Aid for Scientific Research on Priority Areas

Graph Pattern Matching in GQL and SQL/PGQ

As graph databases become widespread, JTC1 -- the committee in joint charge of information technology standards for the International Organization for Standardization (ISO), and International Electrotechnical Commission (IEC) -- has approved a project to create GQL, a standard property graph query language. This complements a project to extend SQL with a new part, SQL/PGQ, which specifies how to define graph views over an SQL tabular schema, and to run read-only queries against them. Both projects have been assigned to the ISO/IEC JTC1 SC32 working group for Database Languages, WG3, which continues to maintain and enhance SQL as a whole. This common responsibility helps enforce a policy that the identical core of both PGQ and GQL is a graph pattern matching sub-language, here termed GPML. The WG3 design process is also analyzed by an academic working group, part of the Linked Data Benchmark Council (LDBC), whose task is to produce a formal semantics of these graph data languages, which complements their standard specifications. This paper, written by members of WG3 and LDBC, presents the key elements of the GPML of SQL/PGQ and GQL in advance of the publication of these new standards

Structural basis for the binding of IRES RNAs to the head of the ribosomal 40S subunit

Some viruses exploit internal initiation for their propagation in the host cell. This type of initiation is facilitated by structured elements (internal ribosome entry site, IRES) upstream of the initiator AUG and requires only a reduced number of canonical initiation factors. An important example are IRES of the virus family Dicistroviridae that bind to the inter-subunit side of the small ribosomal 40S subunit and lead to the formation of elongation-competent 80S ribosomes without the help of any initiation factor. Here, we present a comprehensive functional and structural analysis of eukaryotic-specific ribosomal protein rpS25 in the context of this type of initiation and propose a structural model explaining the essential involvement of rpS25 for hijacking the ribosome

The Future is Big Graphs! A Community View on Graph Processing Systems

Graphs are by nature unifying abstractions that can leverage interconnectedness to represent, explore, predict, and explain real- and digital-world phenomena. Although real users and consumers of graph instances and graph workloads understand these abstractions, future problems will require new abstractions and systems. What needs to happen in the next decade for big graph processing to continue to succeed?Comment: 12 pages, 3 figures, collaboration between the large-scale systems and data management communities, work started at the Dagstuhl Seminar 19491 on Big Graph Processing Systems, to be published in the Communications of the AC

Beyond the Global Brain Differences:Intraindividual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers

BACKGROUND: Carriers of the 1q21.1 distal and 15q11.2 BP1-BP2 copy number variants exhibit regional and globalbrain differences compared with noncarriers. However, interpreting regional differences is challenging if a globaldifference drives the regional brain differences. Intraindividual variability measures can be used to test for regionaldifferences beyond global differences in brain structure.METHODS: Magnetic resonance imaging data were used to obtain regional brain values for 1q21.1 distal deletion (n =30) and duplication (n = 27) and 15q11.2 BP1-BP2 deletion (n = 170) and duplication (n = 243) carriers and matchednoncarriers (n = 2350). Regional intra-deviation scores, i.e., the standardized difference between an individual’sregional difference and global difference, were used to test for regional differences that diverge from the globaldifference.RESULTS: For the 1q21.1 distal deletion carriers, cortical surface area for regions in the medial visual cortex, posterior cingulate, and temporal pole differed less and regions in the prefrontal and superior temporal cortex differedmore than the global difference in cortical surface area. For the 15q11.2 BP1-BP2 deletion carriers, cortical thicknessin regions in the medial visual cortex, auditory cortex, and temporal pole differed less and the prefrontal andsomatosensory cortex differed more than the global difference in cortical thickness.CONCLUSIONS: We find evidence for regional effects beyond differences in global brain measures in 1q21.1 distaland 15q11.2 BP1-BP2 copy number variants. The results provide new insight into brain profiling of the 1q21.1 distaland 15q11.2 BP1-BP2 copy number variants, with the potential to increase understanding of the mechanismsinvolved in altered neurodevelopment

Effects of coping strategies on sociocultural and psychological adjustment of western expatriate managers in the PRC

Western expatriates currently working on the Chinese mainland participated in a mail survey to examine their coping strategies and adjustment to the Chinese work environment. As expected, the results suggest that managers who use problem-focused coping strategies adjust better than those using symptom-focused strategies do. Implications of these findings for Western expatriates assigned to China are discussed.

Corporate expatriate career development

Western business expatriates assigned to Hong Kong responded to a mail survey regarding availability and usage of corporate career development activities. Despite the strategic need for expatriation, it was found that corporate development activities had a low availability indicating little interest on the part of parent organizations to assist in the development of expatriate careers. Large-size parent organizations, with substantial interests in international business operations, generally provide more expatriate career development assistance as opposed to small and medium-sized enterprises with fewer resources and little experience to cater to such needs. Experienced expatriate managers generally use more career development activities than less experienced managers, which could pose a problem for the procurement and advancement of new generations of expatriate managers. Implications of these findings for managers and their employers are discussed in detail.Expatriates Career development Corporate