The early history of Buckingham County

This paper is an attempt to bring together unrelated facts concerning the history or Buckingham County, Virginia. lt is sincerely hoped that one may find the way of life of the early settlers and that this brief history can account (1700-1850), will relate the story or typical Americans in their struggle to establish a foundation that time has tested and found solid. Buckingham County, in the heart of Virginia is one of the most fascinating counties of the Commonwealth. There are three different possibilities from which the county could have received its name. The most prominent idea is that it was named for Buckinghamshire England. Another possibility is that it received its name from a small stream which was once on the lands of Archibald Cary called Buck River. However, the most valid possibility is that the county of Buckingham received its name from the Duke or Buckingham. The latter possibility receives its weight of validity due to the fact that counties of Colonial Virginia were named for royalty

A virtual clinic : telemetric assessment and monitoring for rural and remote areas

This article reports the establishment of a pilot &lsquo;virtual clinic&rsquo; in a rural region of Victoria, Australia. Using low-cost videophones that work across ordinary phone lines, together with off-the-shelf (mostly automatic) clinical tools, local volunteers have been trained to mediate a virtual consultation between simulated patients and local GPs. This system has the potential to save long trips into town by such patients since the traditional &lsquo;home visit&rsquo; is not feasible, as well as to provide regular home monitoring for those with chronic conditions. This in turn should impact favourably on ambulance deployment, sometimes enabling patients to avoid going to hospital or allowing them to come home sooner than otherwise would be the case, and generally to offer a sense of medical security to those living in isolated regions.<br /

Reinventing Britain: British National Identity and the European Economic Community, 1967-1975

The project of European integration has always threatened traditional conceptions of national identity and sovereignty in member states of the European Community (EC), later the European Union. This is especially true in Great Britain, which has had an ambivalent relationship with the rest of Europe. This thesis presents a comparative analysis of two key moments in Britain\u27s relationship with Europe, and thus two key moments for British national identity: the 1967 debate over British membership in the European Community, and the 1975 public referendum over remaining in the Community in which Britons voted to remain inside the EC by a majority of 67.2%. For both moments, it looks at the role that Prime Minister Harold Wilson played in the debates using Parliamentary records and declassified Cabinet papers, as well as the public discourse as seen in letters to the editors of regional British newspapers. In 1967, Britons were largely opposed to EC membership; in 1975 they voted in its favor. This shift can be attributed to a change in how Britons viewed their history. Under the leadership of Harold Wilson, Britons marshaled a new narrative of their history - particularly of their role in World War II - that shifted British national identity closer toward Europe. This shift was not permanent, but the point is that it never could be. National identity itself is impermanent. Though it can have constant pillars, it is ultimately the product of the specific historical narratives to which a nation subscribes. Different stories of the past imply different results for the future. Thus, by aligning behind a new historical narrative, Britons were able to shape their nation\u27s behavior

Industry Analysis on Domestic Petroleum Transportation Industry

Thesis (M.B.A.)--Boston Universit

Care and Handling of Historic Sound Recordings

Manual on the care and handling, and cleaning of historic sound recordings as practiced at the Belfer Audio Archive. Covers cylinders and discs (78s, LPs, ...). Document contains links to videos demonstrating these techniques

Semidiscrete Galerkin modelling of compressible viscous flow past a circular cone at incidence

A numerical study of the laminar and compressible boundary layer, about a circular cone in a supersonic free stream, is presented. It is thought that if accurate and efficient numerical schemes can be produced to solve the boundary layer equations, they can be joined to numerical codes that solve the inviscid outer flow. The combination of these numerical codes is competitive with the accurate, but computationally expensive, Navier-Stokes schemes. The primary goal is to develop a finite element method for the calculation of 3-D compressible laminar boundary layer about a yawed cone. The proposed method can, in principle, be extended to apply to the 3-D boundary layer of pointed bodies of arbitrary cross section. The 3-D boundary layer equations governing supersonic free stream flow about a cone are examined. The 3-D partial differential equations are reduced to 2-D integral equations by applying the Howarth, Mangler, Crocco transformations, a linear relation between viscosity, and a Blasius-type of similarity variable. This is equivalent to a Dorodnitsyn-type formulation. The reduced equations are independent of density and curvature effects, and resemble the weak form of the 2-D incompressible boundary layer equations in Cartesian coordinates. In addition the coordinate normal to the wall has been stretched, which reduces the gradients across the layer and provides high resolution near the surface. Utilizing the parabolic nature of the boundary layer equations, a finite element method is applied to the Dorodnitsyn formulation. The formulation is presented in a Petrov-Galerkin finite element form and discretized across the layer using linear interpolation functions. The finite element discretization yields a system of ordinary differential equations in the circumferential direction. The circumferential derivatives are solved by an implicit and noniterative finite difference marching scheme. Solutions are presented for a 15 deg half angle cone at angles of attack of 5 and 10 deg. The numerical solutions assume a laminar boundary layer with free stream Mach number of 7. Results include circumferential distribution of skin friction and surface heat transfer, and cross flow velocity distributions across the layer

The effects of management and sex on carcasses of yearling cattle

Publication authorized February 17, 1933.Digitized 2007 AES.Includes bibliographical references (page 20)

Insights Into Peptide Inhibition of Alpha-Synuclein Aggregation

α-Synuclein (aSyn) aggregation is an attractive target for therapeutic development fora range of neurodegenerative conditions, collectively termed synucleinopathies. Here,we probe the mechanism of action of a peptide 4554W, (KDGIVNGVKA), previously identified through intracellular library screening, to prevent aSyn aggregation and associated toxicity. We utilize NMR to probe association and identify that 4554Wassociates with a “partially aggregated” form of aSyn, with enhanced association occurring over time. We also report the ability of 4554W to undergo modification through deamidation of the central asparagine residue, occurring on the same timescale asaSyn aggregation in vitro,with peptide modification enhancing its association with aSyn.Additionally, we report that 4554W can act to reduce fibril formation of five Parkinson’s disease associated aSyn mutants. Inhibitory peptide binding to partially aggregated forms of aSyn, as identified here, is particularly attractive from a therapeutic perspective,as it would eliminate the need to administer the therapy at pre-aggregation stages,which are difficult to diagnose. Taken together the data suggest that 4554W could bea suitable candidate for future therapeutic development against wild-type, and most mutant aSyn aggregatio

Evaluation of chemical immersion treatments to reduce microbial populations in fresh beef

The aim of the current study was to assess the ability of a number of chemicals (acetic Acid (AA), citric acid (CA) lactic acid (LA), sodium decanoate (SD) and trisodium phosphate (TSP)) to reduce microbial populations (total viable count, Campylobacter jejuni, Escherichia coli, Salmonella typhimurium and Listeria monocytogenes) on raw beef using an immersion system. The following concentrations of each chemical were used: 3 & 5% for AA, CA, LA, SD and 10 & 12% for TSP. Possible synergistic effects of using combinations of two chemicals sequentially (LA +CA and LA +AA) were also investigated. L*, a* and b* values were measured before and after treatments and ΔE* values were calculated in order to determine any changes in the color of meat due to the use of these chemicals. In general, all chemical treatments resulted in significantly (p \u3c 0.05) reduced bacterial counts when compared to untreated controls. The greatest reductions were obtained by using LA3%, SD5%, AA5%, LA5% and SD3% for TVC, C. jejuni, E. coli, S. typhimurium and L. monocytogenes, respectively. However, no significant difference in microbial load was observed between the different concentrations of each chemical used (p \u3e 0.05). The application of combinations of chemical immersion treatments (LA3%+AA3% and LA3% + CA3%) did not result in further significant reductions in microbial populations when compared to single chemical treatments (P \u3c 0.05). Assessment of color changes in meat following the application of chemical immersion treatments indicated that using AA or CA at either concentration and LA at 5% led to an increase in the ΔE* value of\u3e 3 immediately after treatment and after 24 h storage. The remaining treatments did not result in significant changes to the color of raw beef