626 research outputs found
Non-linear propagation of kink waves to the solar chromosphere
Small-scale magnetic field concentrations (magnetic elements) in the quiet
Sun are believed to contribute to the energy budget of the upper layers of the
Sun's atmosphere, as they are observed to support a large number of MHD modes.
In recent years, kink waves in magnetic elements were observed at different
heights in the solar atmosphere, from the photosphere to the corona. However,
the propagation of these waves has not been fully evaluated. Our aim is to
investigate the propagation of kink waves in small magnetic elements in the
solar atmosphere. We analysed spectropolarimetric data of high-quality and long
duration of a photospheric quiet Sun region observed near the disk center with
the spectropolarimeter CRISP at the Swedish Solar Telescope (SST), and
complemented by simultaneous and co-spatial broad-band chromospheric
observations of the same region. Our findings reveal a clear upward propagation
of kink waves with frequency above mHz. Moreover, the signature of a
non-linear propagation process is also observed. By comparing photospheric to
chromospheric power spectra, no signature of an energy dissipation is found at
least at the atmospheric heights at which the data analysed originate. This
implies that most of the energy carried by the kink waves (within the frequency
range under study mHz) flows to upper layers in the Sun's atmosphere.Comment: A&A accepte
Establishment and characterization of two human breast carcinoma cell lines by spontaneous immortalization: Discordance between Estrogen, Progesterone and HER2/neu receptors of breast carcinoma tissues with derived cell lines
Background: Breast cancer is one of the most common cancers among women throughout the world. Therefore, established cell lines are widely used as in vitro experimental models in cancer research.Methods: Two continuous human breast cell lines, designated MBC1 and MBC2, were successfully established and characterized from invasive ductal breast carcinoma tissues of Malaysian patients. MBC1 and MBC2 have been characterized in terms of morphology analysis, population doubling time, clonogenic formation, wound healing assay, invasion assay, cell cycle, DNA profiling, fluorescence immunocytochemistry, Western blotting and karyotyping.Results: MBC1 and MBC2 exhibited adherent monolayer epithelial morphology at a passage number of 150. Receptor status of MBC1 and MBC2 show (ER+, PR+, HER2+) and (ER+, PR-, HER2+), respectively. These results are in discordance with histopathological studies of the tumoral tissues, which were triple negative and (ER-, PR-, HER2+) for MBC1 and MBC2, respectively. Both cell lines were capable of growing in soft agar culture, which suggests their metastatic potential. The MBC1 and MBC2 metaphase spreads showed an abnormal karyotype, including hyperdiploidy and complex rearrangements with modes of 52-58 chromosomes per cell.Conclusions: Loss or gain in secondary properties, deregulation and specific genetic changes possibly conferred receptor changes during the culturing of tumoral cells. Thus, we hypothesize that, among heterogenous tumoral cells, only a small minority of ER+/PR+/HER2+ and ER+/PR-/HER2+ cells with lower energy metabolism might survive and adjust easily to in vitro conditions. These cell lines will pave the way for new perspectives in genetic and biological investigations, drug resistance and chemotherapy studies, and would serve as prototype models in Malaysian breast carcinogenesis investigations. © 2012 Kamalidehghan et al.; licensee BioMed Central Ltd
High-frequency Oscillations in Small Magnetic Elements Observed with Sunrise/SuFI
We characterize waves in small magnetic elements and investigate their
propagation in the lower solar atmosphere from observations at high spatial and
temporal resolution. We use the wavelet transform to analyze oscillations of
both horizontal displacement and intensity in magnetic bright points found in
the 300 nm and the Ca II H 396.8 nm passbands of the filter imager on board the
Sunrise balloon-borne solar observatory. Phase differences between the
oscillations at the two atmospheric layers corresponding to the two passbands
reveal upward propagating waves at high frequencies (up to 30 mHz). Weak
signatures of standing as well as downward propagating waves are also obtained.
Both compressible and incompressible (kink) waves are found in the small-scale
magnetic features. The two types of waves have different, though overlapping,
period distributions. Two independent estimates give a height difference of
approximately 450+-100 km between the two atmospheric layers sampled by the
employed spectral bands. This value, together with the determined short travel
times of the transverse and longitudinal waves provide us with phase speeds of
29+-2 km/s and 31+-2 km/s, respectively. We speculate that these phase speeds
may not reflect the true propagation speeds of the waves. Thus, effects such as
the refraction of fast longitudinal waves may contribute to an overestimate of
the phase speed.Comment: 14 pages, 7 figure
Epilepsy in Children with Cerebral Palsy
ObjectiveEpilepsy occurs in 12 % to 90 % of children with cerebral palsy (CP). However its clinical course is not well defined. This investigation was undertaken to study and determine the characteristics and prevalence of epilepsy in children with cerebral palsy.Materials & MethodsOf 133 children with cerebral palsy, seen between 1998 and 2001, in the pediatric neurology clinic of the Imam Reza hospital, fifty-three had epilepsy.During the same period, a group of 70 epileptic children with normal neurodevelopmental status was studied as the controls.ResultsPatients with spastic quadriplegia were the most commonly affected with epilepsy. When compared with the control group, children with CP had a higher incidence of epilepsy with onset within the first year of age (52.8% vs. 18.5%), history of neonatal seizures (20.7% vs. 4.2%), and poly therapy (73.6% vs. 29.1%) respectively.ConclusionEpilepsy is common in children with CP and can be predicted if seizures occur in the first year of life ,in the neonatal period and based on the need for polytherapy
Inclinations of small quiet-Sun magnetic features based on a new geometric approach
High levels of horizontal magnetic flux have been reported in the quiet-Sun
internetwork, often based on Stokes profile inversions. Here we introduce a new
method for deducing the inclination of magnetic elements and use it to test
magnetic field inclinations from inversions. We determine accurate positions of
a set of small, bright magnetic elements in high spatial resolution images
sampling different photospheric heights obtained by the Sunrise balloon-borne
solar observatory. Together with estimates of the formation heights of the
employed spectral bands, these provide us with the inclinations of the magnetic
features. We also compute the magnetic inclination angle of the same magnetic
features from the inversion of simultaneously recorded Stokes parameters. Our
new, geometric method returns nearly vertical fields (average inclination of
around 14 deg with a relatively narrow distribution having a standard deviation
of 6 deg). In strong contrast to this, the traditionally used inversions give
almost horizontal fields (average inclination of 75+-8 deg) for the same small
magnetic features, whose linearly polarised Stokes profiles are adversely
affected by noise. The almost vertical field of bright magnetic features from
our geometric method is clearly incompatible with the nearly horizontal
magnetic fields obtained from the inversions. This indicates that the amount of
magnetic flux in horizontal fields deduced from inversions is overestimated in
the presence of weak Stokes signals, in particular if Stokes Q and U are close
to or under the noise level. By combining the proposed method with inversions
we are not just improving the inclination, but also the field strength. This
technique allows us to analyse features that are not reliably treated by
inversions, thus greatly extending our capability to study the complete
magnetic field of the quiet Sun.Comment: 12 pages, 9 figures, 1 table; Accepted for publication in Astronomy &
Astrophysic
Genetic transformation of olive somatic embryos through Agrobacterium tumefaciens and regeneration of transgenic plants
Transformed olive plants were regenerated from inoculated somatic embryos with Agrobacterium tumefacience strain GV3101, which carries the plasmid pBI-P5CS containing Arabidopsis thaliana P5CS cDNA, kanamycin marker (npt) gene and uidA reporter gene. Initially, repetitively embryogenic cultures were established from radicles and cotyledonary segments of mature olive zygotic embryos. Single somatic embryos at cotyledon stage were used for transformation. Through repetitive somatic embryogenesis, non-chimer secondary embryos were selected and propagated on kanamycin containing medium. Resistant embryos were converted to plantlets by subjecting them to desiccation. Transformation and P5CS gene expression was confirmed by β-glucuronidase (GUS) assay polymerase chain reaction (PCR) and reverse transcription (RT)-PCR analysis.Key words: Olea europaea, somatic embryogenesis, transformation, β-glucronidase, P5CS gene
A novel method to design variable gain amplifier
A novel method to design of Variable gain Amplifiers (VGAs) is proposed. A low power VGA with wide range of gain variation and appropriate bandwidth using new technique is presented in this paper. Moreover, the suggested circuit is simulated in whole process corners and different temperatures in the region of -50 to +70 ºC. The circuit has been designed in a typical 0.35μm CMOS process with a power supply of 3.3V, and simulated by HSPICE software using level 49 parameters (BSIM3v3).Keywords: variable gain amplifier; Operational Transconductance Amplifier; wide gain range; low power; unity gain bandwidt
Height dependence of the penumbral fine-scale structure in the inner solar atmosphere
We studied the physical parameters of the penumbra in a large and
fully-developed sunspot, one of the largest over the last two solar cycles, by
using full-Stokes measurements taken at the photospheric Fe I 617.3 nm and
chromospheric Ca II 854.2 nm lines with the Interferometric Bidimensional
Spectrometer. Inverting measurements with the NICOLE code, we obtained the
three-dimensional structure of the magnetic field in the penumbra from the
bottom of the photosphere up to the middle chromosphere. We analyzed the
azimuthal and vertical gradient of the magnetic field strength and inclination.
Our results provide new insights on the properties of the penumbral magnetic
fields in the chromosphere at atmospheric heights unexplored in previous
studies. We found signatures of the small-scale spine and intra-spine structure
of both the magnetic field strength and inclination at all investigated
atmospheric heights. In particular, we report typical peak-to-peak variations
of the field strength and inclination of G and , respectively, in the photosphere, and of G and
in the chromosphere. Besides, we estimated the vertical
gradient of the magnetic field strength in the studied penumbra: we find a
value of G km between the photosphere and the middle
chromosphere. Interestingly, the photospheric magnetic field gradient changes
sign from negative in the inner to positive in the outer penumbra.Comment: 14 page, 9 figures, accepted for Ap
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