Finding the way forward for forensic science in the US:a commentary on the PCAST report

A recent report by the US President’s Council of Advisors on Science and Technology (PCAST) [1] has made a number of recommendations for the future development of forensic science. Whereas we all agree that there is much need for change, we find that the PCAST report recommendations are founded on serious misunderstandings. We explain the traditional forensic paradigms of match and identification and the more recent foundation of the logical approach to evidence evaluation. This forms the groundwork for exposing many sources of confusion in the PCAST report. We explain how the notion of treating the scientist as a black box and the assignment of evidential weight through error rates is overly restrictive and misconceived. Our own view sees inferential logic, the development of calibrated knowledge and understanding of scientists as the core of the advance of the profession

Contribution of problem drug users’ deaths to excess mortality in Scotland: secondary analysis of cohort study

Objectives To examine the “Scottish effect”—namely, the growing divergence between mortality in Scotland and England that is not explained by national differences in levels of deprivation—and, more specifically, to examine the extent to which the Scottish effect is explained by cross national differences in the prevalence of problem drug use

Quantum Vacuum Contribution to the Momentum of the Dielectric Media

Momentum transfer between matter and electromagnetic field is analyzed. The related equations of motion and conservation laws are derived using relativistic formalism. Their correspondence to various, at first sight self-contradicting, experimental data (the so called Abraham-Minkowski controversy) is demonstrated. A new, Casimir like, quantum phenomenon is predicted: contribution of vacuum fluctuations to the motion of dielectric liquids in crossed electric and magnetic fields. Velocities about $50nm/s$ can be expected due to the contribution of high frequency vacuum modes

A response to “Likelihood ratio as weight of evidence: a closer look” by Lund and Iyer

Recently, Lund and Iyer (L&I) raised an argument regarding the use of likelihood ratios in court. In our view, their argument is based on a lack of understanding of the paradigm. L&I argue that the decision maker should not accept the expert’s likelihood ratio without further consideration. This is agreed by all parties. In normal practice, there is often considerable and proper exploration in court of the basis for any probabilistic statement. We conclude that L&I argue against a practice that does not exist and which no one advocates. Further we conclude that the most informative summary of evidential weight is the likelihood ratio. We state that this is the summary that should be presented to a court in every scientific assessment of evidential weight with supporting information about how it was constructed and on what it was based

Dialogue Concerning Two Views on Quantum Coherence: Factist and Fictionist

A controversy that has arisen many times over in disparate contexts is whether quantum coherences between eigenstates of certain quantities are fact or fiction. We present a pedagogical introduction to the debate in the form of a hypothetical dialogue between proponents from each of the two camps: a factist and a fictionist. A resolution of the debate can be achieved, we argue, by recognizing that quantum states do not only contain information about the intrinsic properties of a system but about its extrinsic properties as well, that is, about its relation to other systems external to it. Specifically, the coherent quantum state of the factist is the appropriate description of the relation of the system to one reference frame, while the incoherent quantum state of the fictionist is the appropriate description of the relation of the system to another, uncorrelated, reference frame. The two views, we conclude, are alternative but equally valid paradigms of description.Comment: 14 pages, Contribution to the Int. J. of Quant. Info. issue dedicated to the memory of Asher Peres; v2 updated summary and critique of prior literatur

Exploring Front Line Ambulance Staff Perspectives of the Hospital Transfer Pathway

Guidance from the National Institute for Health and Care Excellence in the UK was introduced in 2015 to improve the quality of the care pathway of transfers of care home residents to hospital when needed. The Red Bag scheme was developed by Sutton Clinical Commissioning Group in 2016 as a means of improving communication between organisations involved in the process by ensuring residents’ notes and other personal belongings were easily identifiable and kept in one place. The Red Bag was implemented in the North East of England in 2018. The aim of this study was to understand the knowledge of and experiences of front line ambulance staff who had potential to be involved with the transfer of care home residents to hospital. A mixed methods approach was used for the study. Participants were recruited by two research paramedics working in the North East ambulance service and approached to take part in a confidential, on-line survey using Survey Monkey®. Data was analysed through descriptive statistics and a constant comparative analytic framework to develop into concepts found in the free text comments, which were constructed into themes. Two hundred and fifty eight participants were recruited to the study. Six themes were identified in the data that represented the knowledge and experiences of the participants. Findings showed there was variance in the implementation, interpretation and use of the Red Bag in practice. Where effective communication took place, handovers worked well, however perceived organisational processes and avoidable delays prevented the optimal transfer of care. Improved communication between organisations is recommended, along with building capacity and capability within and between professional disciplines working at the front line of patient care were identified as fundamental mechanisms of streamlining handover processes for the vulnerable and older adults who live in residential care settings

Sequential Electrostatic Assembly of a Polymer Surfactant Corona Increases Activity of the Phosphotriesterase arPTE

We present a new methodology for the generation of discrete molecularly dispersed enzyme–polymer–surfactant bioconjugates. Significantly, we demonstrate that >3-fold increase in the catalytic efficiency of the diffusion-limited phosphotriesterase arPTE can be achieved through sequential electrostatic addition of cationic and anionic polymer surfactants, respectively. Here, the polymer surfactants assemble on the surface of the enzyme via ion exchange to yield a compact corona. The observed rate enhancement is consistent with a mechanism whereby the polymer–surfactant corona gives rise to a decrease in the dielectric constant in the vicinity of the active site of the enzyme, accelerating the rate-determining product diffusion step. The facile methodology has significant potential for increasing the efficiency of enzymes and could therefore have a substantially positive impact for industrial enzymology

Attacking Group Protocols by Refuting Incorrect Inductive Conjectures

Automated tools for finding attacks on flawed security protocols often fail to deal adequately with group protocols. This is because the abstractions made to improve performance on fixed 2 or 3 party protocols either preclude the modelling of group protocols all together, or permit modelling only in a fixed scenario, which can prevent attacks from being discovered. This paper describes Coral, a tool for finding counterexamples to incorrect inductive conjectures, which we have used to model protocols for both group key agreement and group key management, without any restrictions on the scenario. We will show how we used Coral to discover 6 previously unknown attacks on 3 group protocols

Is cell-to-cell scale variability necessary in reservoir models?

Reservoir models typically contain hundreds-of-thousands to millions of grid cells in which petrophysical properties such as porosity and permeability vary on a cell-to-cell basis. However, although the petrophysical properties of rocks do vary on a point-to-point basis, this variability is not equivalent to the cell-to-cell variations in models. We investigate the impact of removing cell-to-cell variability on predictions of fluid flow in reservoir models. We remove cell-to-cell variability from models containing hundreds of thousands of unique porosity and permeability values to yield models containing just a few tens of unique porosity and permeability values grouped into a few internally homogeneous domains. The flow behavior of the original model is used as a reference. We find that the impact of cell-to-cell variability on predicted flow is small. Cell-to-cell variability is not necessary to capture flow in reservoir models; rather, it is the spatially correlated variability in petrophysical properties that is important. Reservoir modelling effort should focus on capturing correlated geologic domains in the most realistic and computationally efficient manner