883 research outputs found

    A Global Perspective: NASA's Prediction of Worldwide Energy Resources (POWER) Project

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    The Prediction of the Worldwide Energy Resources (POWER) Project, initiated under the NASA Science Mission Directorate Applied Science Energy Management Program, synthesizes and analyzes data on a global scale that are invaluable to the renewable energy industries, especially to the solar and wind energy sectors. The POWER project derives its data primarily from NASA's World Climate Research Programme (WCRP)/Global Energy and Water cycle Experiment (GEWEX) Surface Radiation Budget (SRB) project (Version 2.9) and the Global Modeling and Assimilation Office (GMAO) Goddard Earth Observing System (GEOS) assimilation model (Version 4). The latest development of the NASA POWER Project and its plans for the future are presented in this paper

    Identification of Power System Stability Using Relevant Modes

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    The purpose of this investigation is to identify appropriate location of capacitor banks and sources of reactive power by studying power system stability in the vicinity of system equilibrium states. The locations for reactive power sources are determined by identifying those modes of the system that participate most in the system behavior in general and in dictating the final state of the system after experiencing faults or disturbances. To identify the relevant modes of the system that participate most in the system dynamic, we shall make use of modal and participation analysis for different system conditions. We also apply modal and participation analysis to a system in order to identify the components of greatest impact that result in the most efficient system control. The ideas developed in this study are used to analyze and identify weak boundaries of the IEEE 39- Bus system that contribute to the system’s instability

    Identification of Power System Stability Using Relevant Modes

    Get PDF
    The purpose of this investigation is to identify appropriate location of capacitor banks and sources of reactive power by studying power system stability in the vicinity of system equilibrium states. The locations for reactive power sources are determined by identifying those modes of the system that participate most in the system behavior in general and in dictating the final state of the system after experiencing faults or disturbances. To identify the relevant modes of the system that participate most in the system dynamic, we shall make use of modal and participation analysis for different system conditions. We also apply modal and participation analysis to a system in order to identify the components of greatest impact that result in the most efficient system control. The ideas developed in this study are used to analyze and identify weak boundaries of the IEEE 39- Bus system that contribute to the system’s instability

    Reviving Mercy in the Structure of Capital Punishment

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    State based model of long-term potentiation and synaptic tagging and capture

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    Recent data indicate that plasticity protocols have not only synapse-specific but also more widespread effects. In particular, in synaptic tagging and capture (STC), tagged synapses can capture plasticity-related proteins, synthesized in response to strong stimulation of other synapses. This leads to long-lasting modification of only weakly stimulated synapses. Here we present a biophysical model of synaptic plasticity in the hippocampus that incorporates several key results from experiments on STC. The model specifies a set of physical states in which a synapse can exist, together with transition rates that are affected by high- and low-frequency stimulation protocols. In contrast to most standard plasticity models, the model exhibits both early- and late-phase LTP/D, de-potentiation, and STC. As such, it provides a useful starting point for further theoretical work on the role of STC in learning and memory

    Dioxin Toxicity In Vivo Results from an Increase in the Dioxin-Independent Transcriptional Activity of the Aryl Hydrocarbon Receptor

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    The Aryl hydrocarbon receptor (Ahr) is the nuclear receptor mediating the toxicity of dioxins -widespread and persistent pollutants whose toxic effects include tumor promotion, teratogenesis, wasting syndrome and chloracne. Elimination of Ahr in mice eliminates dioxin toxicity but also produces adverse effects, some seemingly unrelated to dioxin. Thus the relationship between the toxic and dioxin-independent functions of Ahr is not clear, which hampers understanding and treatment of dioxin toxicity. Here we develop a Drosophila model to show that dioxin actually increases the in vivo dioxin-independent activity of Ahr. This hyperactivation resembles the effects caused by an increase in the amount of its dimerisation partner Ahr nuclear translocator (Arnt) and entails an increased transcriptional potency of Ahr, in addition to the previously described effect on nuclear translocation. Thus the two apparently different functions of Ahr, dioxin-mediated and dioxin-independent, are in fact two different levels (hyperactivated and basal, respectively) of a single function

    Self-Similar Interpolation in Quantum Mechanics

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    An approach is developed for constructing simple analytical formulae accurately approximating solutions to eigenvalue problems of quantum mechanics. This approach is based on self-similar approximation theory. In order to derive interpolation formulae valid in the whole range of parameters of considered physical quantities, the self-similar renormalization procedure is complimented here by boundary conditions which define control functions guaranteeing correct asymptotic behaviour in the vicinity of boundary points. To emphasize the generality of the approach, it is illustrated by different problems that are typical for quantum mechanics, such as anharmonic oscillators, double-well potentials, and quasiresonance models with quasistationary states. In addition, the nonlinear Schr\"odinger equation is considered, for which both eigenvalues and wave functions are constructed.Comment: 1 file, 30 pages, RevTex, no figure

    Adenosine A2A receptor modulation of hippocampal CA3-CA1 synapse plasticity during associative learning in behaving mice

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    © 2009 Nature Publishing Group All rights reservedPrevious in vitro studies have characterized the electrophysiological and molecular signaling pathways of adenosine tonic modulation on long-lasting synaptic plasticity events, particularly for hippocampal long-term potentiation(LTP). However, it remains to be elucidated whether the long-term changes produced by endogenous adenosine in the efficiency of synapses are related to those required for learning and memory formation. Our goal was to understand how endogenous activation of adenosine excitatory A2A receptors modulates the associative learning evolution in conscious behaving mice. We have studied here the effects of the application of a highly selective A2A receptor antagonist, SCH58261, upon a well-known associative learning paradigm - classical eyeblink conditioning. We used a trace paradigm, with a tone as the conditioned stimulus (CS) and an electric shock presented to the supraorbital nerve as the unconditioned stimulus(US). A single electrical pulse was presented to the Schaffer collateral–commissural pathway to evoke field EPSPs (fEPSPs) in the pyramidal CA1 area during the CS–US interval. In vehicle-injected animals, there was a progressive increase in the percentage of conditioning responses (CRs) and in the slope of fEPSPs through conditioning sessions, an effect that was completely prevented (and lost) in SCH58261 (0.5 mg/kg, i.p.)-injected animals. Moreover, experimentally evoked LTP was impaired in SCH58261- injected mice. In conclusion, the endogenous activation of adenosine A2A receptors plays a pivotal effect on the associative learning process and its relevant hippocampal circuits, including activity-dependent changes at the CA3-CA1 synapse.This study was supported by grants from the Spanish Ministry of Education and Research (BFU2005-01024 and BFU2005-02512), Spanish Junta de Andalucía (BIO-122 and CVI-02487), and the Fundación Conocimiento y Cultura of the Pablo de Olavide University (Seville, Spain).B. Fontinha was in receipt of a studentship from a project grant (POCI/SAU-NEU/56332/2004) supported by Fundação para a Ciência e Tecnologia (FCT, Portugal), and of an STSM from Cost B30 concerted action of the EU

    A self-rectifying TaOy/nanoporous TaOx memristor synaptic array for learning and energy-efficient neuromorphic systems

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    The human brain intrinsically operates with a large number of synapses, more than 10(15). Therefore, one of the most critical requirements for constructing artificial neural networks (ANNs) is to achieve extremely dense synaptic array devices, for which the crossbar architecture containing an artificial synaptic node at each cross is indispensable. However, crossbar arrays suffer from the undesired leakage of signals through neighboring cells, which is a major challenge for implementing ANNs. In this work, we show that this challenge can be overcome by using Pt/TaOy/nanoporous (NP) TaOx/Ta memristor synapses because of their self-rectifying behavior, which is capable of suppressing unwanted leakage pathways. Moreover, our synaptic device exhibits high non-linearity (up to 10(4)), low synapse coupling (S.C, up to 4.00 x 10(-5)), acceptable endurance (5000 cycles at 85 degrees C), sweeping (1000 sweeps), retention stability and acceptable cell uniformity. We also demonstrated essential synaptic functions, such as long-term potentiation (LTP), long-term depression (LTD), and spiking-timing-dependent plasticity (STDP), and simulated the recognition accuracy depending on the S.C for MNIST handwritten digit images. Based on the average S.C (1.60 x 10(-4)) in the fabricated crossbar array, we confirmed that our memristive synapse was able to achieve an 89.08% recognition accuracy after only 15 training epochs
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