Spin-0 bosons near rotating stars

In this work we study the effects of rotating stars on the behavior of bosons close to their surfaces. For this task, metrics determined by the rotation of these stars will be taken into account. We will consider the Klein-Gordon equation in the Hartle-Thorne metric and in the one proposed by Berti et al. by considering some kinds of stars. Pions and Higgs bosons will be investigated as examples. By solving the equations, the main effect that may be observed is a rotational phase, $\delta_R$, that depends on the angular momentum of the star, $J$, in the wave function of the boson. Corrections of higher orders in $J$ are also investigated

Morphometric analysis of collagen in placentomes of dairy cows with normal delivery and with placental retention

The goal of this study was to quantify, by morphometric method, the collagen of maternal and fetal portions of dairy cows placentomes with normal delivery and with placental retention. Twelve cows were used and a placentome was obtained from each one soon after fetal expulsion. Eight cows showed normal placental delivery (Group 1) and four cows showed placental retention (Group 2). From each placentome a fragment was obtained, histologically processed and stained by Masson’s Trichromic. Volumetric proportions of maternal and fetal collagen were determined with a 25 point ocular (Zeiss K PL ocular 10xwith 25 points). There was no significant difference between groups (p>0.05) in volumetric proportion of maternal collagen (34.57 ± 5.47 and 32.04 ± 5.82, respectively) and in volumetric proportion of fetal collagen (9.85 ± 2,04 and 10.73 ± 2.47, respectively).O objetivo deste estudo foi quantificar, através de método morfométrico, o colágeno da porção fetal e da porção materna do placentoma de vacas leiteiras com liberação normal e com retenção de placenta. Foram utilizadas 12 vacas, das quais foi colhido um placentoma, imediatamente após a expulsão fetal, sendo que oito apresentaram liberação normal da placenta e constituíram o Grupo 1 e quatro apresentaram retenção e constituíram o Grupo 2. De cada placentoma foi obtido um fragmento que foi processado histologicamente. As lâminas foram coradas pelo Tricrômico de Masson. As proporções volumétricas do colágeno materno e do colágeno fetal foram determinadas com o auxílio de uma ocular integradora (Ocular integradora Zeiss KPL 10x com 25 pontos). Não houve diferença significativa entre grupos 1 e 2 (p>0,05), tanto na proporção volumétrica do colágeno materno (34,57 ± 5,47 e 32,04 ± 5,82, respectivamente) quanto na proporção volumétrica do colágeno fetal (9.85 ± 2,04 e 10,73 ± 2,47, respectivamente)

Natural Disasters and Financial Technology Adoption

This paper investigates the adoption of financial technology, with a specific focus on the introduction of a new instant payment technology called PIX by the Brazilian Central Bank. To assess adoption patterns, we use Brazilian data and leverage the occurrence of natural disasters in Brazilian municipalities as an exogenous variation. Our empirical findings indicate that adopting the new payment technology increases after a natural disaster, with increases in transaction volume ranging from 6.4% to 8.9% after eight months. Furthermore, we document that changes in other banking transactions do not drive these findings. We also conduct a series of analyses to confirm the robustness of our results in the context of the COVID-19 pandemic, the seasonality of tourist cities, and the number of bank branches

Proporção volumétrica dos componentes estruturais da placenta caprina ao longo da gestação

The goal of this research was to determine the volumetric proportions of the structural components of the goat placenta throughout gestation. We used nine goats of nondefined breed, separated into groups A, B and C, with 90, 120 and 150 days of gestation, respectively. From each animal fragments of three placentomes were obtained, one removed from the base, another from the middle part and the other from the end of the gestational uterine horn. The fragments were fixed in Bouin solution and histologically processed according to the standard techniques and stained with hematoxilin-eosin. Microscopically, a 25-point circular grid (Zeiss KPL ocular 6.3x with 25 points) was randomly used across the placentome to determine the volumetric proportion of the maternal and fetal connective tissue, syncytium, trophoblastic epithelium and binucleate cells. An increase of volumetric proportion of the syncytium was found at the end of gestation and also a decrease of volumetric proportion of fetal connective tissue in the same period.O objetivo deste estudo foi determinar as proporções volumétricas dos componentes estruturais da placenta caprina ao longo da gestação. Foram utilizadas nove cabras adultas sem raça definida, separadas em grupos A, B e C, com 90, 120 e 150 dias de gestação, respectivamente. De cada animal foram colhidos fragmentos de três placentomas, sendo um localizado na base do corno uterino, outro no terço médio e o último da extremidade. Os fragmentos foram fixados em solução de Bouin, processados segundo as técnicas rotineiras de inclusão em parafina e corados pela hematoxilina e eosina. Microscopicamente, uma ocular integradora (Ocular Zeiss KPL 6,3x com 25 pontos) foi aleatoriamente sobreposta sobre a secção do placentoma para a determinação da proporção volumétrica do tecido conjuntivo materno e fetal, do sincício, do epitélio trofoblástico e das células binucleadas. Foi observado aumento na proporção volumétrica do sincício ao final da gestação e diminuição do tecido conjuntivo fetal no mesmo período

Relationship between periodontitis and rheumatoid arthritis and the effect of non-surgical periodontal treatment

This study analyzed the association of periodontal disease (PD) and rheumatoid arthritis (RA). Seventy-five 35-60-year-old patients were assigned to 5 groups according to the presence (+) or not (-) of PD and RA and the treatment received (TR+) or not (TR-) for PD. Group 3 uses total prosthesis (TP). Clinical and laboratory evaluations were performed at baseline, 3 and 6 months of follow-up by probing pocket depth, bleeding on probing and plaque index for PD, HAQ, DAS28, SF-36 and laboratory: AAG, ESR, CRP for RA. Statistically significant differences for PD after 3 (p=0.0055) and after 6 months (p=0.0066) were obtained in Group 1 (RA+PD+TR+) and 2(RA+PD+TR-); significant reduction in the % of BOP after 6 months (p=0.0128) and significant reduction in the % of Pl after 3 (p=0.0128) and 6 months (p=0.0002) in Group 1. Statistically significant differences between Groups 1 and 3 (RA+TP) for DAS28 at baseline and after 3 months were observed, but not after 6 months. No other parameters for RA were significantly affected. The relationship between RA and PD disease activities is not clear, but the importance of periodontal treatment in the control of inflammation to avoid tooth extraction is evident.Este estudo avaliou a influência da doença periodontal (DP) na artrite reumatóide (AR). 75 pacientes, 35-60 anos, divididos em 5 Grupos, considerando a situação sistêmica e periodontal foram analisados. Um Grupo usava prótese total (PT). Os parâmetros clínicos e laboratoriais analisados: inicial, 3 e 6 meses receberam tratamento estatístico. As correlações entre as reduções da profundidade de sondagem, placa microbiana e sangramento à sondagem com as de Alfa 1, PCR, VHS e exames de qualidade de vida (HAQ, DAS28, SF36) foram também analisadas. Comparando o Grupo 1 (AR+DP+TR+) e Grupo 2 (AR+DP+TR-), aqueles que receberam tratamento periodontal não-cirúrgico (TPNC) tiveram reduções estatisticamente significativas em relação a PS aos 3 meses (p=0,0055) e 6 meses (p=0,0066); as reduções da % SS foram estatisticamente significantes aos 6 meses (p=0,0128) e da % PM aos 3 (p=0,0128) e 6 meses (p=0,0002). O TPNC não apresentou correlação com a melhora dos exames laboratoriais, nem com os exames de qualidade de vida. Comparando o Grupo 1 com o Grupo 3 (AR+PT) houve diferença estatisticamente significante no DAS28 inicial e 3 meses. Não foi possível verificar uma correlação direta do TPNC na atividade da doença sistêmica, mas pode-se constatar a sua importância, evitando a extração múltipla dos dentes

Desvelando a relação entre ideologia, valores do indivíduo e estilo de consumo

This article aims to answer the question about the relationship between the values of an individual and their frequency of consumption. It develops a discussion on the theoretical and conceptual term “value”, on the formation of individualistic ideology and consumer society. For empirical verification, it applies three questionnaires validated in the literature to measure cultural values (ideologies), individual values and frequency of consumption in a population of 226 subjects. On the basis of the use of multivariate techniques of data analysis (correlations, regression and structural equations) and theoretical support, it was possible to coin the term “social elected”, meaning individuals who seek, on the basis of consumption, to demonstrate to society power, authority and status, independently of groups, legitimated by the values of freedom and equality, which guarantee that all can pursue the same condition of elected.Key words: values, individualism, consumption, social elected, structural equations.Este artigo pretende responder qual a relação entre os valores do indivíduo e sua frequência de consumo. Para isso, desenvolve-se uma discussão teórico-conceitual sobre o termo valor, sobre a formação da ideologia individualista e da sociedade de consumo. Para verificação empírica, aplicam-se três questionários validados na literatura, para medir valores culturais (ideologias), valores individuais e frequência de consumo em uma população de 226 elementos. A partir da utilização de técnicas multivariadas de análise de dados (correlações, regressão e equações estruturais) e com respaldo teórico, foi possível cunhar o termo eleito social, ou seja, indivíduos que buscam, a partir do consumo, demonstrar, diante da sociedade, poder, autoridade e status, independentemente de grupos, legitimados pelos valores liberdade e igualdade, que garantem a todos buscar a mesma condição de eleito.Palavras-chave: valores, individualismo, consumo, eleito social, equações estruturais

Short-Term effect of COX-2 selective inhibitor as an adjunct for the treatment of periodontal disease: a clinical double-blind study in humans

Adjunctive therapeutic strategies that modulate the inflammatory mediators can play a significant role in periodontal therapy. In this double-blind, placebo-controlled study, 60 subjects diagnosed as periodontitis patients were evaluated for 28 days after periodontal treatment combined with selective cyclooxygenase-2 (COX-2) inhibitor. The experimental group received scaling and root planning (SRP) combined with the Loxoprofen antiinflammatory drug (SRP+Loxoprofen). The control group received SRP combined with placebo (SRP+placebo). Plaque index (PI), probing pocket depth (PD) and bleeding on probing (BOP) were monitored with an electronic probe at baseline and after 14 and 28 days. Both groups displayed clinical improvement in PD, PI and BOP. They also showed statistically similar values (p>0.05) of PD reduction on day 14 (0.4 mm) and on day 28 (0.6 mm). At the baseline, few deeper sites (>7 mm) from SRP+Loxoprofen group were responsible and most PD reduction was observed after 14 days (p<0.05). The percentage of remaining deep pockets (>7 mm) after 14 days in the SRP+Loxoprofen group was significantly lower (p<0.05) than in the SRP+placebo group. Loxoprofen presents potential effect as an adjunct of periodontal disease treatment, but long-term clinical trials are necessary to confirm its efficacy.Estratégias terapêuticas adjuvantes que modulam os mediadores inflamatórios podem ter função significante na terapia periodontal. Neste estudo duplo-cego controlado com placebo, 60 indivíduos diagnosticados com periodontite foram avaliados por 28 dias após tratamento periodontal combinado com inibidor seletivo de COX-2. O grupo experimental foi tratado com raspagem e alisamento radicular combinado com medicação anti-inflamatória Loxoprofeno (RAR+Loxoprofen). O grupo controle foi tratado com raspagem e alisamento radicular combinado com medicação placebo (Raspagem e alisamento radicular - RAR+placebo). Presença de placa (PI), profundidade de sondagem (PS) e sangramento à sondagem (SS) foram monitoradas com auxílio de uma sonda computadorizada no início do estudo e após 14 e 28 dias. Os dois grupos demonstraram melhora clínica em relação a PS, PI e SS. Também foi observado valores semelhantes (p>0,05) de redução da PS nos períodos de 14 dias (0,4 mm) e 28 dias (0,6 mm). No início do estudo, alguns sítios profundos (>7 mm) do grupo RAR+Loxoprofen foram os responsáveis pela maior redução da PS depois de 14 dias (p<0,05). A porcentagem de bolsas periodontais profundas >7 mm após 14 dias no grupo RAR+Loxoprofen foi significativamente inferior do que o grupo RAR+placebo (p<0.05). A medicação Loxoprofen apresenta potencial efeito adjuvante à terapia periodontal, mas estudos de longo prazo são necessários para confirmar sua eficácia.Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)FAPESPSankyo Pharma Ltda

Five-Year Outcome in Stroke Patients Submitted to Thrombolysis

BACKGROUND AND PURPOSE: Little is known on long-term follow-up after thrombolysis in ischemic stroke patients because the majority of studies evaluated outcome at 3 to 12 months. We aimed to assess 5-year outcome after intravenous thrombolysis (IVT). METHODS: Cohort study based on the prospective registry of all consecutive ischemic stroke patients submitted to IVT in our Stroke Unit. Five-year outcome, including living settings, functional outcome, stroke recurrence, and mortality, was ascertained by telephonic interviews and additional review of clinical records. Multivariate analyses were performed to identify predictors of outcome and mortality. Excellent outcome was defined as modified Rankin scale 0 to 1. RESULTS: Five-year outcome was available for 155/164 patients submitted to IVT. At 5 years, 32.9% of patients had an excellent outcome (95% confidence interval (CI) =25.5-43.3) and mortality was 43.9% (95%CI=36.1-51.7). Increasing age (odds ratio =0.93, 95% CI =0.90-0.97) and increasing National Institute of Health Stroke Scale (NIHSS) 24 h after thrombolysis (odds ratio =0.81, 95% CI =0.74-0.90) were independently associated with a lower likelihood of an excellent 5-year outcome. Age (hazards ratio =1.07, 95% CI =1.03-1.11) and excellent functional outcome 3 months after thrombolysis (hazards ratio =0.28, 95%CI=0.12-0.66) were independently associated with mortality during follow-up. CONCLUSIONS: One third of ischemic stroke patients have excellent 5-year outcome after IVT. Younger age, lower NIHSS 24 h after IVT, and excellent 3-month functional outcome are independent predictors of excellent 5-year outcome

Diastolic tolerance to systolic pressures closely reflects systolic performance in patients with coronary heart disease

In animal experiments, elevating systolic pressures induces diastolic dysfunction and may contribute to congestion, a finding not yet translated to humans. Coronary surgery patients (63 ± 8 years) were studied with left ventricular (LV) pressure (n = 17) or pressure-volume (n = 3) catheters, immediately before cardiopulmonary bypass. Single-beat graded pressure elevations were induced by clamping the ascending aorta. Protocol was repeated after volume loading (n = 7). Consecutive patients with a wide range of systolic function were included. Peak isovolumetric LV pressure (LVP(iso)) ranged from 113 to 261 mmHg. With preserved systolic function, LVP elevations neither delayed relaxation nor increased filling pressures. With decreasing systolic function, diastolic tolerance to afterload progressively disappeared: relaxation slowed and filling pressures increased (diastolic dysfunction). In severely depressed systolic function, filling pressures increased even with minor LVP elevations, suggesting baseline load-dependent elevation of diastolic pressures. The magnitude of filling pressure elevation induced in isovolumetric heartbeats was closely and inversely related to systolic performance, evaluated by LVP(iso) (r = -0.96), and directly related to changes in the time constant of relaxation τ (r = 0.95). The maximum tolerated systolic LVP (without diastolic dysfunction) was similarly correlated with LVP(iso) (r = 0.99). Volume loading itself accelerated relaxation, but augmented afterload-induced upward shift of filling pressures (7.9 ± 3.7 vs. 3.0 ± 1.5; P < 0.01). The normal human response to even markedly increased systolic pressures is no slowing of relaxation and preservation of normal filling pressures. When cardiac function deteriorates, the LV becomes less tolerant, responding with slowed relaxation and increased filling pressures. This increase is exacerbated by volume loading

Análise morfométrica do colágeno no placentoma dc vacas leiteiras com liberação normal e com retenção de placentas

O objetivo deste estudo foi quantificar, através de método morfométrico, o colágeno da porção fetal e da porção materna do placentoma de vacas leiteiras com liberação normal e com retenção de placenta. Foram utilizadas 12 vacas, das quais foi colhido um placentoma, imediatamente após a expulsão fetal, sendo que oito apresentaram liberação normal da placenta e constituíram o Grupo 1 e quatro apresentaram retenção e constituíram o Grupo 2. De cada placentoma foi obtido um fragmento que foi processado histologicamente. As lâminas foram coradas pelo Tricrômico de Masson. As proporções volumétricas do colágeno materno e do colágeno fetal foram determinadas com o auxílio de uma ocular integradora (Ocular integradora Zeiss KPL 10x com 25 pontos). Não houve diferença significativa entre grupos 1 e 2 (p>0,05), tanto na proporção volumétrica do colágeno materno (34,57 ± 5,47 e 32,04 ± 5,82, respectivamente) quanto na proporção volumétrica do colágeno fetal (9.85 ± 2,04 e 10,73 ± 2,47, respectivamente)