BPS black holes in N=2 D=4 gauged supergravities

We construct and analyze BPS black hole solutions in gauged N=2, D=4 supergravity with charged hypermultiplets. A class of solutions can be found through spontaneous symmetry breaking in vacua that preserve maximal supersymmetry. The resulting black holes do not carry any hair for the scalars. We demonstrate this with explicit examples of both asymptotically flat and anti-de Sitter black holes. Next, we analyze the BPS conditions for asymptotically flat black holes with scalar hair and spherical or axial symmetry. We find solutions only in cases when the metric contains ripples and the vector multiplet scalars become ghost-like. We give explicit examples that can be analyzed numerically. Finally, we comment on a way to circumvent the ghost-problem by introducing also fermionic hair.Comment: 40 pages, 2 figures; v2 references added; v3 minor changes, published versio

Pre-operative diagnosis of an unusual complication of abdominal aortic aneurysm on multidetector computed tomography: a case report

Spontaneous fistulation of an abdominal aortic aneurysm (AAA) into the inferior vena cava (IVC) is an unusual and infrequently encountered complication in clinical practice. In the majority of cases, it is a diagnosis made on the operating table, during surgical repair of AAA. We report a patient with an aortocaval fistula diagnosed preoperatively on multidetector computed tomography (MDCT). Preoperative diagnosis of this rare complication is important as it allows appropriate anaesthetic and surgical planning thereby reducing morbidity and mortality

Multiplexed charge-locking device for large arrays of quantum devices

We present a method of forming and controlling large arrays of gate-defined quantum devices. The method uses an on-chip, multiplexed charge-locking system and helps to overcome the restraints imposed by the number of wires available in cryostat measurement systems. The device architecture that we describe here utilises a multiplexer-type scheme to lock charge onto gate electrodes. The design allows access to and control of gates whose total number exceeds that of the available electrical contacts and enables the formation, modulation and measurement of large arrays of quantum devices. We fabricate such devices on n-type GaAs/AlGaAs substrates and investigate the stability of the charge locked on to the gates. Proof-of-concept is shown by measurement of the Coulomb blockade peaks of a single quantum dot formed by a floating gate in the device. The floating gate is seen to drift by approximately one Coulomb oscillation per hour.This work was supported by the Engineering and Physical Sciences Research Council Grant No. EP/K004077/1.This is the author accepted manuscript. The final version is available from AIP via http://dx.doi.org/10.1063/1.493201

Small Horizons

All near horizon geometries of supersymmetric black holes in a N=2, D=5 higher-derivative supergravity theory are classified. Depending on the choice of near-horizon data we find that either there are no regular horizons, or horizons exist and the spatial cross-sections of the event horizons are conformal to a squashed or round S^3, S^1 * S^2, or T^3. If the conformal factor is constant then the solutions are maximally supersymmetric. If the conformal factor is not constant, we find that it satisfies a non-linear vortex equation, and the horizon may admit scalar hair.Comment: 21 pages, latex. Typos corrected and reference adde

Implementation of a comprehensive intervention for patients at high risk of cardiovascular disease in rural China: A pragmatic cluster randomized controlled trial

Objective: This study aims to assess whether a standard intervention package of cardiovascular disease (CVD) care was being delivered effectively, and if it was associated with improved lifestyle and biomedical indicators. Methods: In rural China, we implemented a pragmatic cluster randomized controlled trial for 12 months, randomized at the township hospital level, and compared with usual care. Intervention case management guideline, training and performance monitoring meeting and patient support activities were designed to fit within the job description of family doctors in the township hospitals and comprised: 1) prescription of a standardised package of medicines targeted at those with hypertension or diabetes; 2) advice about specific lifestyle interventions; and 3) advice about medication adherence. Participants were 50-74 years old, had hypertension and CVD risk scores >20% or diabetes, but were excluded if a history of severe CVD events. We also randomly selected 100 participants from six selected clusters per arm as a panel to collect intermediate biomedical indicators over time. Results: A total of 28,130 participants, in 33 intervention and 34 control township hospitals, were recruited. Compared with the control arm, participants in the intervention arm had substantially improved prescribing rates of anti-hypertensives, statins and aspirin (P0.05). Conclusion: Implementation of the package by family doctors was feasible and improved prescribing and some lifestyle changes. Additional measures such as reducing medication costs and patient education are required. Trial registration: Current Controlled Trials ISRCTN58988083

A possible method for non-Hermitian and non-PTPT-symmetric Hamiltonian systems

A possible method to investigate non-Hermitian Hamiltonians is suggested through finding a Hermitian operator $\eta_+$ and defining the annihilation and creation operators to be $\eta_+$-pseudo-Hermitian adjoint to each other. The operator $\eta_+$ represents the $\eta_+$-pseudo-Hermiticity of Hamiltonians. As an example, a non-Hermitian and non-$PT$-symmetric Hamiltonian with imaginary linear coordinate and linear momentum terms is constructed and analyzed in detail. The operator $\eta_+$ is found, based on which, a real spectrum and a positive-definite inner product, together with the probability explanation of wave functions, the orthogonality of eigenstates, and the unitarity of time evolution, are obtained for the non-Hermitian and non-$PT$-symmetric Hamiltonian. Moreover, this Hamiltonian turns out to be coupled when it is extended to the canonical noncommutative space with noncommutative spatial coordinate operators and noncommutative momentum operators as well. Our method is applicable to the coupled Hamiltonian. Then the first and second order noncommutative corrections of energy levels are calculated, and in particular the reality of energy spectra, the positive-definiteness of inner products, and the related properties (the probability explanation of wave functions, the orthogonality of eigenstates, and the unitarity of time evolution) are found not to be altered by the noncommutativity.Comment: 15 pages, no figures; v2: clarifications added; v3: 16 pages, 1 figure, clarifications made clearer; v4: 19 pages, the main context is completely rewritten; v5: 25 pages, title slightly changed, clarifications added, the final version to appear in PLOS ON

Exact Black Holes and Universality in the Backreaction of non-linear Sigma Models with a potential in (A)dS4

The aim of this paper is to construct accelerated, stationary and axisymmetric exact solutions of the Einstein theory with self interacting scalar fields in (A)dS4. To warm up, the backreaction of the (non)-minimally coupled scalar field is solved, the scalar field equations are integrated and all the potentials compatible with the metric ansatz and Einstein gravity are found. With these results at hand the non-linear sigma model is tackled. The scalar field Lagrangian is generic; neither the coupling to the curvature, neither the metric in the scalar manifold nor the potential, are fixed ab initio. The unique assumption in the analysis is the metric ansatz: it has the form of the most general Petrov type D vacuum solution of general relativity; it is a a cohomogeneity two Weyl rescaling of the Carter metric and therefore it has the typical Plebanski-Demianski form with two arbitrary functions of one variable and one arbitrary functions of two variables. It is shown, by an straightforward manipulation of the field equations, that the metric is completely integrable without necessity of specifiying anything in the scalar Lagrangian. This results in that the backreaction of the scalar fields, within this class of metrics, is universal. The metric functions generically show an explicit dependence on a dynamical exponent that allows to smoothly connect this new family of solutions with the actual Plebanski-Demianski spacetime. The remaining field equations imply that the scalar fields follow geodesics in the scalar manifold with an affine parameter given by a non-linear function of the spacetime coordinates and define the on-shell form of the potential plus a functional equation that it has to satisfy. Finally, a general family of (A)dS4 static hairy black holes is explicitly constructed and its properties are outlined.Comment: Several typos correcte

Rotating BPS black holes in matter-coupled AdS(4) supergravity

Using the general recipe given in arXiv:0804.0009, where all timelike supersymmetric solutions of N=2, D=4 gauged supergravity coupled to abelian vector multiplets were classified, we construct genuine rotating supersymmetric black holes in AdS(4) with nonconstant scalar fields. This is done for the SU(1,1)/U(1) model with prepotential F=-iX^0X^1. In the static case, the black holes are uplifted to eleven dimensions, and generalize the solution found in hep-th/0105250 corresponding to membranes wrapping holomorphic curves in a Calabi-Yau five-fold. The constructed rotating black holes preserve one quarter of the supersymmetry, whereas their near-horizon geometry is one half BPS. Moreover, for constant scalars, we generalize (a supersymmetric subclass of) the Plebanski-Demianski solution of cosmological Einstein-Maxwell theory to an arbitrary number of vector multiplets. Remarkably, the latter turns out to be related to the dimensionally reduced gravitational Chern-Simons action.Comment: 23 pages, uses JHEP3.cl

Site-specific incorporation of phosphotyrosine using an expanded genetic code.

Access to phosphoproteins with stoichiometric and site-specific phosphorylation status is key to understanding the role of protein phosphorylation. Here we report an efficient method to generate pure, active phosphotyrosine-containing proteins by genetically encoding a stable phosphotyrosine analog that is convertible to native phosphotyrosine. We demonstrate its general compatibility with proteins of various sizes, phosphotyrosine sites and functions, and reveal a possible role of tyrosine phosphorylation in negative regulation of ubiquitination