18 research outputs found

    Protective role of Telfairia occidentalis in irradiation-induced oxidative stress in rat brain

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    This study aimed at evaluating the protective role of Telfairia occidentalis extract (TOE) irradiationinduced oxidative stress in rat brain. Aqueous TOE was administered orally to adult rats for 30 days at doses of 400 mg/kg body weight, 800 mg/kg body weight and 1600 mg/kg body weight, and a corresponding group of rats were treated with 50 mg/kg body weight vitamin E (VE), a standard antioxidant before irradiation at a dose of 2 Gy of gamma rays. The control rats received distilled water only. The rats were observed and sacrificed at 24 hours, 15 and 30 days post-irradiation. The results demonstrated a significant increase in levels of malondialdehyde (MDA), an end product of lipid peroxidation (LPO) and hydrogen peroxide (H2O2) generation with a concomitant decrease in the activities of  superoxide dismutase (SOD), glutathione peroxidase (GSH-Px),  glutathione-S-transferase (GST), a phase two xenobiotic metabolizing enzyme, and a corresponding decrease in the level of reduced glutathione (GSH) after twenty-four hours, 15 and 30 days post-irradiation compared with the control. Treatments with TOE and VE significantly reversed  oxidative stress of irradiated rats when compared with the control rats. In conclusion, supplementation with TOE could reduce radiationinduced biochemical disorders in brain tissues.Keywords: Gamma radiation, oxidative stress, brain, rats and Telfairia occidentalis

    Climate change adaptation options in farming communities of selected Nigerian ecological zones

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    This chapter examines the impacts of climate change on three tropical crops and assesses the climate change adaptation options adopted by rural farmers in the region. The study was conducted among farming communities settled in three major ecological zones in Nigeria. Over 37 years of data on rainfall and temperature were analyzed to examine climate change impacts on three major crops: rice, maize, and cassava. Farmers' adaptive capacity was assessed with a survey. Climatic data, crop yields, and survey data were analyzed using both descriptive and inferential statistics. The relation between rainfall/temperature and crop yields was examined using the Pearson correlation coefficient. Results show a high variation in the annual rainfall and temperature during the study period. The major findings from this research is that crops in different ecological zones respond differently to climate variation. The result revealed that there is a very strong relationship between precipitation and the yield of rice and cassava at p <0.05 level of significance. The results further showed low level of adaption among the rural farmers. The study concludes that rainfall and temperature variability has a significant impact on crop yield in the study area, but that the adaptive capacity of most farmers to these impacts is low. There is a need for enhancing the adaptation options available to farmers in the region, which should be the focus of government policies

    Robust decision making for a climate-resilient development of the agricultural sector in Nigeria.

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    Adaptation options that work reasonably well across an entire range of potential outcomes are shown to be preferable in a context of deep uncertainty. This is because robust practices that are expected to perform satisfactorily across the full range of possible future conditions, are preferable to those that are the best ones, but just in one specific scenario. Thus, using a Robust Decision Making Approach in Nigerian agriculture may increase resilience to climate change. To illustrate, the expansion of irrigation might be considered as a complementary strategy to conservation techniques and a shift in sowing/planting dates to enhance resilience of agriculture. However, given large capital expenditures, irrigation must consider climate trends and variability. Using historical climate records is insufficient to size capacity and can result in "regrets" when the investment is undersized/oversized, if the climate turns out to be drier/wetter than expected. Rather utilizing multiple climate outcomes to make decisions will decrease "regrets." This chapter summarizes the main results from a study titled "Toward climate-resilient development in Nigeria" funded by the Word Bank (See Cervigni et al. 2013)
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