Factors influencing the development and carbohydrate metabolism of Echinococcus granulosus in dogs

Echinococcus granulosus adult worms, 35 days postinfection, were measured for dispersion in the intestines of 10 dogs, a range of morphological characters, and the excreted end products of carbohydrate catabolism following 4 hr incubation in vitro. Most worms were found in the proximal sections of the small intestine, but the pattern of dispersion differed between dogs. Worm development varied both between dogs and between different regions of the small intestine of individual dogs. Overall there was a high level of variability with no simple patterns. Worm metabolism was related to worm development and, also independently, to local population density within the intestine. Larger, more mature worms produced less lactate and, at higher densities. worms tended to produce more acetate and succinate (pathways with a higher energy yield than lactate) and less ethanol. Thus, both more developed worms and high population density are associated with a shift from cytosolic to mitochondrial metabolism. The variation between worm populations along the small intestine along with the observed variation between worm populations from sibling dogs infected with genetically identical parasites suggests that the local host environment has a significant effect on parasite development

Spin-Flavor Structure of Large N Baryons

The spin-flavor structure of large N baryons is described in the 1/N expansion of QCD using quark operators. The complete set of quark operator identities is obtained, and used to derive an operator reduction rule which simplifies the 1/N expansion. The operator reduction rule is applied to the axial currents, masses, magnetic moments and hyperon non-leptonic decay amplitudes in the $SU(3)$ limit, to first order in $SU(3)$ breaking, and without assuming $SU(3)$ symmetry. The connection between the Skyrme and quark representations is discussed. An explicit formula is given for the quark model operators in terms of the Skyrme model operators to all orders in $1/\N$ for the two flavor case.Comment: 36 pages, 2 eps figures, uses revte

Red Optical Planet Survey : A radial velocity search for low mass M dwarf planets

This is an Open Access article distributed under the terms of the Creative Commons Attribution License 2.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly citedWe present radial velocity results from our Red Optical Planet Survey (ROPS), aimed at detecting low-mass planets orbiting mid-late M dwarfs. The similar to 10 ms(-1) precision achieved over 2 consecutive nights with the MIKE spectrograph at Magellan Clay is also found on week long timescales with UVES at VLT. Since we find that UVES is expected to attain photon limited precision of order 2 ms-1 using our novel deconvolution technique, we are limited only by the

Factors required for the successful aquaculture of black bream (Acanthopagrus butcheri) in inland water bodies

The results of this project will contribute to the on-going development and success of inland black bream recreational fisheries and the inland saline aquaculture industry in general. Several commercial black bream fish-out ventures are now operational in inland Western Australia, one of which utilises saline groundwater. It has been proposed that a pilot project to stock the saline pools of the upper Avon River, which is located in the heart of the W.A. Wheatbelt, should be undertaken to provide recreational fishing opportunities for the inhabitants of a number of rural towns. The continued development of the W.A. inland saline aquaculture industry will result in social and economic benefits to rural areas through increased tourism and opportunities for farm diversification

Echinococcus as a model system: biology and epidemiology

The introduction of Echinococcus to Australia over 200 years ago and its establishment in sheep rearing areas of the country inflicted a serious medical and economic burden on the country. This resulted in an investment in both basic and applied research aimed at learning more about the biology and life cycle of Echinococcus. This research served to illustrate the uniqueness of the parasite in terms of developmental biology and ecology, and the value of Echinococcus as a model system in a broad range of research, from fundamental biology to theoretical control systems. These studies formed the foundation for an international, diverse and ongoing research effort on the hydatid organisms encompassing stem cell biology, gene regulation, strain variation, wildlife diseases and models of transmission dynamics. We describe the development, nature and diversity of this research, and how it was initiated in Australia but subsequently has stimulated much international and collaborative research on Echinococcus

Associations of inflammatory and hemostatic variables with the risk of recurrent stroke

<p><b>Background and Purpose:</b> Several prospective studies have shown significant associations between plasma fibrinogen, viscosity, C-reactive protein (CRP), fibrin D-dimer, or tissue plasminogen activator (tPA) antigen and the risk of primary cardiovascular events. Little has been published on the associations of these variables with recurrent stroke. We studied such associations in a nested case-control study derived from the Perindopril Protection Against Recurrent Stroke Study (PROGRESS).</p> <p><b>Methods:</b> Nested case-control study of ischemic (n=472) and hemorrhagic (n=83) strokes occurring during a randomized, placebo-controlled multicenter trial of perindopril-based therapy in 6105 patients with a history of stroke or transient ischemic attack. Controls were matched for age, treatment group, sex, region, and most recent qualifying event at entry to the parent trial.</p> <p><b>Results:</b> Fibrinogen and CRP were associated with an increased risk of recurrent ischemic stroke after accounting for the matching variables and adjusting for systolic blood pressure, smoking, peripheral vascular disease, and statin and antiplatelet therapy. The odds ratio for the last compared with the first third of fibrinogen was 1.34 (95% CI, 1.01 to 1.78) and for CRP was 1.39 (95% CI, 1.05 to 1.85). After additional adjustment for each other, these 2 odds ratios stayed virtually unchanged. Plasma viscosity, tPA, and D-dimer showed no relationship with recurrent ischemic stroke, although tPA was significant for lacunar and large artery subtypes. Although each of these variables showed a negative relationship with recurrent hemorrhagic stroke, none of these relationships achieved statistical significance.</p> <p><b>Conclusions:</b> Fibrinogen and CRP are risk predictors for ischemic but not hemorrhagic stroke, independent of potential confounders.</p&gt

Density correlations in ultracold atomic Fermi gases

We investigate density fluctuations in a coherent ensemble of interacting fermionic atoms. Adapting the concept of full counting statistics, well-known from quantum optics and mesoscopic electron transport, we study second-order as well as higher-order correlators of density fluctuations. Using the mean-field BCS state to describe the whole interval between the BCS limit and the BEC limit, we obtain an exact expression for the cumulant-generating function of the density fluctuations of an atomic cloud. In the two-dimensional case, we obtain a closed analytical expression. Poissonian fluctuations of a molecular condensate on the BEC side are strongly suppressed on the BCS side. The size of the fluctuations in the BCS limit is a direct measure of the pairing potential. We also discuss the BEC-BCS crossover of the third cumulant and the temperature dependence of the second cumulant.Comment: 4 pages, 4 figures. To appear in Phys. Rev. A. New calculation of the bin statistics of a free Bose gas; updated and extended bibliograph

Thinking about growth : a cognitive mapping approach to understanding small business development

School of Managemen

Benchmark low-mass objects in Moving Groups

This is an Open Access article distributed under the terms of the Creative Commons Attribution License 2.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.In order to compile a sample of ultracool dwarfs that will serve as benchmarks for testing theoretical formation and evolutionary models, we selected low-mass cool (>M7) objects that are potentially members of five known young Moving Groups in the solar neighbourhood. We have studied the kinematics of the sample, finding that 49 targets belong to the young disk area, from which 36 are kinematic member of one of the five moving groups under study. Some of the identified low-mass members have been spectroscopically characterised (T-eff, log g) and confirmed as young members through a detailed study of age indicators

The sub-stellar birth rate from UKIDSS

We present a new sample of mid-L to mid-T dwarfs with effective temperatures of 11001700 K selected from the UKIDSS Large Area Survey (LAS) and confirmed with infrared spectra from X-shooter/Very Large Telescope. This effective temperature range is especially sensitive to the formation history of Galactic brown dwarfs and allows us to constrain the form of the sub-stellar birth rate, with sensitivity to differentiate between a flat (stellar like) birth rate and an exponentially declining form. We present the discovery of 63 new L and T dwarfs from the UKIDSS LAS DR7, including the identification of 12 likely unresolved binaries, which form the first complete sub-set from our programme, covering 495 square degrees of sky, complete to J = 18.1. We compare our results for this sub-sample with simulations of differing birth rates for objects of masses 0.10-0.03 M-circle dot and ages 1-10 Gyr. We find that the more extreme birth rates (e. g. a halo type form) can likely be excluded as the true form of the birth rate. In addition, we find that although there is substantial scatter we find a preference for a mass function, with a power-law index a in the range -1 <alpha <0 that is consistent (within the errors) with the studies of late T dwarfs.Peer reviewe