14 research outputs found
Recent incidence of type 1 diabetes mellitus in children 0–14 years in Newfoundland and Labrador, Canada climbs to over 45/100,000: a retrospective time trend study
Background: To study and update the provincial incidence of type 1 diabetes mellitus (T1DM) in Newfoundland
and Labrador (NL), a province of Canada with a very high incidence previously reported in 2006, and one of
the highest incidences reported worldwide. This is a retrospective time trend study of the incidence of T1DM,
in children aged 0–14 years from 1987–2010 inclusive.
Findings: Over the study period 931 children aged 0–14 years were diagnosed with T1DM. The incidence of
T1DM in this population over the period 1987 – 2010 inclusive was 37.7 per 100,000 per year (95% CI 35. 3, 40.2)
The incidence from 2007–2010 was 49.9 per 100,000 per year (95% CI 42.2, 57.6). The incidence over this 24 year
period increased by a factor of 1.03 per 100,000 per year.
Conclusion: NL has one of the highest incidences of T1DM reported worldwide. Potential reasons for the very high
incidence could be related to the unique genetic background of the population, northern latitude and vitamin D
insufficiency, low breastfeeding rates, and high rates of cesarean section
Use of Trichoderma harzianum in combination or alternation with fungicides to control cucumber grey mould (Botrytis cinerea) under commercial greenhouse conditions
Consultation on assessment of the health risk dioxins;re-evaluation of the tolerable daily intake (TDI): Executive Summary
Defining animal welfare standards in hunting: body mass determines thresholds for incapacitation time and flight distance
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