Differentiating the Effects of Animal-Assisted Versus Equine Facilitated Psychotherapy on Positive Psychological Outcomes Through a Stress Induction Context

The unique benefits of Equine Facilitated Psychotherapy (EFP) such as the human-horse bond, a non-traditional therapy setting, and performing altruistic acts are thought to facilitate positive change in humans. One mechanism by which positive changes occur is through improved coping and resilience in the face of stress. To date, only a handful of correlational studies speak to the potential effects of EFP on resilience-based outcomes. Thus, this study sought to address this gap in the literature by exploring the benefits of EFP compared to traditional Animal Assisted Therapy (AAT) in an experimental context. Specifically, we examined the effects of different intervention (EFP vs. AAT vs. control) on three resilience-based outcomes (i.e., positive affect, well-being, and altruism). In addition, we wanted to ascertain whether participation in specific types of psychological interventions may buffer the negative effects of stress on these resilience-based outcomes. In an online study, participants were randomly assigned to one of three conditions and asked to listen to a 10-minute audio guided imagery exercise depicting an EFP, AAT, or control group intervention. Participants were then asked to complete a number of surveys, including measures of stress, affect, well-being, and altruism. Overall, results did not reveal any significant differences in stress reduction, mood, or well-being across conditions. Additionally, analyses did not reveal any moderating effects of intervention type on the relationship between stress and resilience-based outcomes. One significant finding indicates that, contrary to our prediction, participants in the EFP group reported lower levels of altruism than the other two groups. Overall, the results of the current study do not lend significant support for the use of EFP as an effective approach in managing stress and increasing resilience-based outcomes. A number of notable limitations in the current study are discussed as well as suggestions for addressing these issues in future research

Aspirin inhibits the acute venodilator response to furosemide in patients with chronic heart failure

OBJECTIVES: We sought to determine the effect of aspirin on the venodilator effect of furosemide in patients with chronic heart failure (CHF) BACKGROUND: Furosemide has an acute venodilator effect preceding its diuretic action, which is blocked by nonsteroidal anti-inflammatory drugs. The ability of therapeutic doses of aspirin to block this effect of furosemide in patients with CHF has not been studied. For comparison, the venodilator response to nitroglycerin (NTG) was also studied. METHODS: Eleven patients with CHF were randomized to receive placebo, aspirin at 75 mg/day or aspirin at 300 mg/day for 14 days in a double-blind, crossover study. The effect of these pretreatments on the change in forearm venous capacitance (FVC) after 20 mg of intravenous furosemide was measured over 20 min by using venous occlusion plethysmography. In a second study, the effect of 400 μg of sublingual NTG on FVC was documented in 11 similar patients (nine participated in the first study). RESULTS: Mean arterial pressure, heart rate and forearm blood flow did not change in response to furosemide. After placebo pretreatment, furosemide caused an increase in FVC of 2.2% (95% confidence interval [CI] −0.9% to 5.2%; mean response over 20 min). By comparison, FVC fell by −1.1% (95% CI −4.2% to 1.9%) after pretreatment with aspirin at 75 mg/day, and by −3.7% (95% CI −6.8% to −0.7%) after aspirin at 300 mg/day (p = 0.020). In the second study, NTG increased FVC by 2.1% (95% CI −1.6% to 5.8%) (p = 0.95 vs. furosemide). CONCLUSIONS: In patients with CHF, venodilation occurs within minutes of the administration of intravenous dose of furosemide. Our observation that aspirin inhibits this effect further questions the use of aspirin in patients with CHF

Cost-effectiveness findings from the Agewell pilot study of behaviour change to promote health and wellbeing in later life

Background: Participation in cognitive and physical activities may help to maintain health and wellbeing in older people. The Agewell study explored the feasibility of increasing cognitive and physical activity in older people through a goal-setting approach. This paper describes the findings of the cost-effectiveness analysis.Method: Individuals over the age of 50 and attending an Agewell centre in North Wales were randomised to one of three conditions: control (IC), goal-setting (GS), or goal-setting with mentoring (GM). We undertook a cost-effectiveness analysis comparing GS vs. IC, GM vs. IC and GM vs. GS. The primary outcome measure for this analysis was the QALY, calculated using the EQ-5D. Participants’ health and social care contacts were recorded and costed using national unit costs.Results: Seventy participants were followed-up at 12 months. Intervention set up and delivery costs were £252 per participant in the GS arm and £269 per participant in the GM arm. Mean health and social care costs over 12 months were £1,240 (s.d. £3,496) per participant in the IC arm, £1,259 (s.d. £3,826) per participant in the GS arm and £1,164 (s.d. £2,312) per participant in the GM arm. At a willingness to pay threshold of £20,000 per QALY there was a 65% probability that GS was cost-effective compared to IC (ICER of £1,070). However, there was only a 41% probability that GM was cost-effective compared to IC (ICER of £2,830) at a threshold of £20,000 per QALY.Conclusion: Setting up and running the community based intervention was feasible. Due to the small sample size it is not possible to draw a firm conclusion about cost-effectiveness; however, our preliminary results suggest that goalsetting is likely to be cost-effective compared to the control condition of no goal-setting, the addition of mentoring was effective but not cost-effective

Search for a-Cluster States in the Giant Resonance Region

Supported by the National Science Foundation and Indiana Universit

Towards Landslide Predictions: Two Case Studies

In a previous work [Helmstetter, 2003], we have proposed a simple physical model to explain the accelerating displacements preceding some catastrophic landslides, based on a slider-block model with a state and velocity dependent friction law. This model predicts two regimes of sliding, stable and unstable leading to a critical finite-time singularity. This model was calibrated quantitatively to the displacement and velocity data preceding two landslides, Vaiont (Italian Alps) and La Clapi\`ere (French Alps), showing that the former (resp. later) landslide is in the unstable (resp. stable) sliding regime. Here, we test the predictive skills of the state-and-velocity-dependent model on these two landslides, using a variety of techniques. For the Vaiont landslide, our model provides good predictions of the critical time of failure up to 20 days before the collapse. Tests are also presented on the predictability of the time of the change of regime for la Clapi\`ere landslide.Comment: 30 pages with 12 eps figure

A Study of the Scintillation Induced by Alpha Particles and Gamma Rays in Liquid Xenon in an Electric Field

Scintillation produced in liquid xenon by alpha particles and gamma rays has been studied as a function of applied electric field. For back scattered gamma rays with energy of about 200 keV, the number of scintillation photons was found to decrease by 64+/-2% with increasing field strength. Consequently, the pulse shape discrimination power between alpha particles and gamma rays is found to reduce with increasing field, but remaining non-zero at higher fields.Comment: 15 pages, 12 figures, accepted by Nuclear Instruments and Methods in Physics Research

Muon studies of Li+ diffusion in LiFePO4 nanoparticles of different polymorphs

The lithium diffusion in nanostructured olivine LiFePO4 has been investigated for the first time using muon spectroscopy (μSR). A microwave-assisted approach has been employed for nanoparticle preparation, where the choice of solvent is shown to play an important role in determining particle morphology and crystal chemistry. Two phases have been obtained: Pnma LiFePO4 and the high pressure Cmcm phase. The Li+ diffusion behaviour is strikingly different in both phases, with DLi of 6.25 × 10−10 cm2 s−1 obtained for Pnma LiFePO4 in good agreement with measurements of bulk materials. In contrast, Li+ diffusion is impeded with the addition of the high pressure Cmcm phase, with a lower DLi of 3.96 × 10−10 cm2 s−1 noted. We have demonstrated an efficient microwave route to nanoparticle synthesis of positive electrode materials and we have also shown μSR measurements to be a powerful probe of Li+ diffusion behaviour in nanoparticles

DT/T beyond linear theory

The major contribution to the anisotropy of the temperature of the Cosmic Microwave Background (CMB) radiation is believed to come from the interaction of linear density perturbations with the radiation previous to the decoupling time. Assuming a standard thermal history for the gas after recombination, only the gravitational field produced by the linear density perturbations present on a $\Omega\neq 1$ universe can generate anisotropies at low z (these anisotropies would manifest on large angular scales). However, secondary anisotropies are inevitably produced during the nonlinear evolution of matter at late times even in a universe with a standard thermal history. Two effects associated to this nonlinear phase can give rise to new anisotropies: the time-varying gravitational potential of nonlinear structures (Rees-Sciama RS effect) and the inverse Compton scattering of the microwave photons with hot electrons in clusters of galaxies (Sunyaev-Zeldovich SZ effect). These two effects can produce distinct imprints on the CMB temperature anisotropy. We discuss the amplitude of the anisotropies expected and the relevant angular scales in different cosmological scenarios. Future sensitive experiments will be able to probe the CMB anisotropies beyong the first order primary contribution.Comment: plain tex, 16 pages, 3 figures. Proceedings of the Laredo Advance School on Astrophysics "The universe at high-z, large-scale structure and the cosmic microwave background". To be publised by Springer-Verla