260 research outputs found

    Screening Blood Donors at Risk for Malaria: Reply to Hänscheid et al.

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    Physics of Eclipsing Binaries: Modelling in the new era of ultra-high precision photometry

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    Recent ultra-high precision observations of eclipsing binaries, especially data acquired by the Kepler satellite, have made accurate light curve modelling increasingly challenging but also more rewarding. In this contribution, we discuss low-amplitude signals in light curves that can now be used to derive physical information about eclipsing binaries but that were unaccessible before the Kepler era. A notable example is the detection of Doppler beaming, which leads to an increase in flux when a star moves towards the satellite and a decrease in flux when it moves away. Similarly, Rømer delays, or light travel time effects, also have to taken into account when modelling the supreme quality data that is now available. The detection of offsets between primary and secondary eclipse phases in binaries with extreme mass ratios, and the observation of Rømer delays in the signals of pulsators in binary stars, have allowed us to determine the orbits of several binaries without the need for spectroscopy. A third example of a small-scale effect that has to be taken into account when modelling specific binary systems, are lensing effects. A new binary light curve modelling code, PHOEBE 2.0, that takes all these effect into account is currently being developed

    Eclipsing Binaries in Open Clusters

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    Detached eclipsing binaries are very useful objects for calibrating theoretical stellar models and checking their predictions. Detached eclipsing binaries in open clusters are particularly important because of the additional constraints on their age and chemical composition from their membership of the cluster. I compile a list containing absolute parameters of well-studied eclipsing binaries in open clusters, and present new observational data on the B-type systems V1481 Cyg and V2263 Cyg which are members of the young open cluster NGC 7128.Comment: 4 pages, 2 colour figures. Poster presentation for IAUS 240 (Binary Stars as Critical Tools and Tests in Contemporary Astrophysics), Prague, August 2006. The poster itself can be dowloaded in ppt and pdf versions from http://www.astro.keele.ac.uk/~jkt/pubs.htm

    Against all odds? Forming the planet of the HD196885 binary

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    HD196885Ab is the most "extreme" planet-in-a-binary discovered to date, whose orbit places it at the limit for orbital stability. The presence of a planet in such a highly perturbed region poses a clear challenge to planet-formation scenarios. We investigate this issue by focusing on the planet-formation stage that is arguably the most sensitive to binary perturbations: the mutual accretion of kilometre-sized planetesimals. To this effect we numerically estimate the impact velocities dvdv amongst a population of circumprimary planetesimals. We find that most of the circumprimary disc is strongly hostile to planetesimal accretion, especially the region around 2.6AU (the planet's location) where binary perturbations induce planetesimal-shattering dvdv of more than 1km/s. Possible solutions to the paradox of having a planet in such accretion-hostile regions are 1) that initial planetesimals were very big, at least 250km, 2) that the binary had an initial orbit at least twice the present one, and was later compacted due to early stellar encounters, 3) that planetesimals did not grow by mutual impacts but by sweeping of dust (the "snowball" growth mode identified by Xie et al., 2010b), or 4) that HD196885Ab was formed not by core-accretion but by the concurent disc instability mechanism. All of these 4 scenarios remain however highly conjectural.Comment: accepted for publication by Celestial Mechanics and Dynamical Astronomy (Special issue on EXOPLANETS

    Thrombocytogenesis by megakaryocyte; Interpretation by protoplatelet hypothesis

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    Serial transmission electron microscopy of human megakaryocytes (MKs) revealed their polyploidization and gradual maturation through consecutive transition in characteristics of various organelles and others. At the beginning of differentiation, MK with ploidy 32N, e.g., has 16 centrosomes in the cell center surrounded by 32N nucleus. Each bundle of microtubules (MTs) emanated from the respective centrosome supports and organizes 16 equally volumed cytoplasmic compartments which together compose one single 32N MK. During the differentiation, single centriole separated from the centriole pair, i.e., centrosome, migrates to the most periphery of the cell through MT bundle, corresponding to a half of the interphase array originated from one centrosome, supporting one “putative cytoplasmic compartment” (PCC). Platelet demarcation membrane (DM) is constructed on the boundary surface between neighbouring PCCs. Matured PCC, composing of a tandem array of platelet territories covered by a sheet of DM is designated as protoplatelet. Eventually, the rupture of MK results in release of platelets from protoplatelets

    Olfactory Jump Reflex Habituation in Drosophila and Effects of Classical Conditioning Mutations

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    Habituation is a nonassociative learning mechanism, in which an initial response toward repeated stimuli gradually wanes. This is amongst the simplest and most widespread forms of behavioral plasticity. So far, neither the underlying molecular mechanisms nor the precise neural networks of habituation are well understood. We have developed a novel paradigm to quantify habituation of the olfactory jump reflex in Drosophila. We present data demonstrating several behavioral properties of this phenomenon, generally observed in other species. We also show that the dunce and rutabaga memory mutants behave abnormally in this assay, suggesting that this assay might be used in behavioral screens for new mutants with defects in this simpler form of behavioral plasticity

    Hiring New Key Inventors to Improve Firms’ Post-M&A Inventive Output

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    Although merger and acquisitions (M&As) are acknowledged as an important means to access innovative assets and know-how, firms’ inventive output often declines in the post-M&A period. Financial, managerial and organizational constraints related to the M&A event contribute to inventive output declines and inventors’ departure. Prior literature treats the acquiring firm as a passive observer of invention declines. This study argues that acquiring firms can take measures by hiring new key inventors. We show that the hiring of new key inventors in the post-M&A period can counteract invention declines in two ways. First, these newly hired inventors are associated with an increase of corporate inventive output after the M&A. Second, they are also associated with an improved inventive output of inventors already working for the acquiring firm. These results suggest that an appropriate hiring policy can counteract declining inventive output of firms in the aftermath of M&As
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