4,856 research outputs found

    The Brownian net

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    Match Probability Statistics and Gamma Ray Burst Recurrences in the BATSE Catalog

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    We develop match probability statistics to test the recurrences of gamma ray bursts in the BATSE catalog 1B and 2B. We do not find a signal of repetitions at the match level of 1.e-3.Comment: 4 pages, LaTeX, two macros included (kluwer.sty, spacekap.sty) To appear in the proceedings of the Eslab29 symposium, ``gamma ray bursts: toward the source

    Spectroscopic characterization of 1.3Β΅m GaInNAs quantum-well structures grown by metal-organic vapor phase epitaxy

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    We report optical studies of high-quality 1.3 μm strain-compensated GaInNAs/GaAs single-quantum-well structures grown by metalorganic vapor phase epitaxy. Photoluminescence excitation (PLE) spectroscopy shows clearly the electronic structure of the two-dimensional quantum well. The transition energies between quantized states of the electrons and holes are in agreement with theoretical calculations based on the band anti-crossing model in which the localized N states interact with the extended states in the conduction band. We also investigated the polarization properties of the luminescence by polarized edge-emission measurements. Luminescence bands with different polarization characters arising from the electron to heavy-hole and light-hole transitions, respectively, have been identified and verify the transition assignment observed in the PLE spectrum

    Crystal Nucleation by Laser-Induced Cavitation\ud

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    High-speed and high-resolution photography have been used to investigate the relationship between creation, expansion, and collapse of a vapor cavity induced by a 6 ns laser pulse and the subsequent nucleation of crystals. A thin layer of supersaturated aqueous solutions of (NH4)2SO4 and KMnO4 was confined between two glass plates with a separation of 50 and 100 ΞΌm. The expansion and collapse of the laser-induced vapor bubble occurred over a total time scale of 200 ΞΌs, while the first identifiable crystal appears one second after the laser pulse. Crystals were observed to form on a ring with a diameter of 70 ΞΌm centered in the focal point of the laser. The ring is preceded by an optical disturbance observed through the cavity around 30–50 ΞΌs after the laser pulse and vapor cavity formation. This ring-shaped optical disturbance originates from changes in refractive index induced by crystal nuclei formation. The formation of the nuclei most probably coincides with the formation of the bubble, when the rate of evaporation and the supersaturation are at their maxima. Apparently, it takes the nuclei around 30–50 ΞΌs to grow to a particle size with a visible optical disturbanc

    The renormalization transformation of two-type branching models

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    Article / Letter to editorMathematisch Instituu

    Superconducting Order Parameter in Bi-Layer Cuprates: Occurrence of Ο€\pi Phase Shifts in Corner Junctions

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    We study the order parameter symmetry in bi-layer cuprates such as YBaCuO, where interesting Ο€\pi phase shifts have been observed in Josephson junctions. Taking models which represent the measured spin fluctuation spectra of this cuprate, as well as more general models of Coulomb correlation effects, we classify the allowed symmetries and determine their associated physical properties. Ο€\pi phase shifts are shown to be a general consequence of repulsive interactions, independent of whether a magnetic mechanism is operative. While it is known to occur in d-states, this behavior can also be associated with (orthorhombic) s-symmetry when the two sub-band gaps have opposite phase. Implications for the magnitude of TcT_c are discussed.Comment: 5 pages, RevTeX 3.0, 9 figures (available upon request

    Phonon thermal conductivity in doped La2CuO4\rm\bf La_2CuO_4: Relevant scattering mechanisms

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    Results of in-plane and out-of-plane thermal conductivity measurements on La1.8βˆ’xEu0.2SrxCuO4\rm La_{1.8-x}Eu_{0.2}Sr_xCuO_4 (0≀x≀0.20\leq x\leq0.2) single crystals are presented. The most characteristic features of the temperature dependence are a pronounced phonon peak at low temperatures and a steplike anomaly at TLTT_{LT}, i.e., at the transition to the low temperature tetragonal phase (LTT-phase), which gradually decrease with increasing Sr-content. Comparison of these findings with the thermal conductivity of La2βˆ’xSrxCuO4\rm La_{2-x}Sr_xCuO_4 and La2NiO4\rm La_2NiO_4 clearly reveals that in La2βˆ’xSrxCuO4\rm La_{2-x}Sr_xCuO_4 the most effective mechanism for phonon scattering is impurity-scattering (dopants), as well as scattering by soft phonons that are associated with the lattice instability in the low temperature orthorhombic phase (LTO-phase). There is no evidence that stripe correlations play a major role in suppressing the phonon peak in the thermal conductivity of La2βˆ’xSrxCuO4\rm La_{2-x}Sr_xCuO_4.Comment: 7 pages, 4 figure

    Paclitaxel-octreotide conjugates inhibit growth of human non-small cell lung cancer cells in vitro

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    Aim: To evaluate the effects of paclitaxel-octreotide conjugates on the growth of cultured non-small cell lung cancer cells. Methods: RT-PCR was performed to detect mRNA for the subtypes of the human somatostatin receptor (SSTR) using specific primers. MTT-based cytotoxicity assay was used to evaluate the cell viability after treatment with paclitaxel and the conjugates. Cell cycle perturbations were determined using a Fluorescence-Activated Cell Sorter. Results: Non-small cell lung cancer A549 and Calu-6 cells expressed mRNA for SSTR2 and SSTR5. Paclitaxel and the conjugates effectively inhibited the growth of A549 and Calu-6 cells in a concentration- and time-dependent manner. In SSTR-negative fibroblasts, the conjugates were less cytotoxic than paclitaxel. The conjugates and paclitaxel could induce the increase of G2/M phase ratio in A549 cells. Conclusion: The paclitaxel-octreotide conjugates can be used as selective-targeted chemotherapeutic agents for treating non-small cell lung cancer.ЦСль: ΠΎΡ†Π΅Π½ΠΈΡ‚ΡŒ эффСкт ΠΊΠΎΠ½ΡŠΡŽΠ³Π°Ρ‚ΠΎΠ² паклитаксСла-ΠΎΠΊΡ‚Ρ€Π΅ΠΎΡ‚ΠΈΠ΄Π° Π½Π° рост ΠΊΡƒΠ»ΡŒΡ‚ΠΈΠ²ΠΈΡ€ΠΎΠ²Π°Π½Π½Ρ‹Ρ… ΠΊΠ»Π΅Ρ‚ΠΎΠΊ Π½Π΅ΠΌΠ΅Π»ΠΊΠΎΠΊΠ»Π΅Ρ‚ΠΎΡ‡Π½ΠΎΠ³ΠΎ Ρ€Π°ΠΊΠ° Π»Π΅Π³ΠΊΠΎΠ³ΠΎ Ρ‡Π΅Π»ΠΎΠ²Π΅ΠΊΠ°. ΠœΠ΅Ρ‚ΠΎΠ΄Ρ‹: для опрСдСлСния мРНК ΠΏΠΎΠ΄Ρ‚ΠΈΠΏΠΎΠ² Ρ€Π΅Ρ†Π΅ΠΏΡ‚ΠΎΡ€Π° соматостатина Ρ‡Π΅Π»ΠΎΠ²Π΅ΠΊΠ° (SSTR) примСняли ОT-ПЦР. Анализ цитотоксичности Π² МВВ-тСстС примСняли для ΠΎΡ†Π΅Π½ΠΊΠΈ выТиваСмости ΠΊΠ»Π΅Ρ‚ΠΎΠΊ послС ΠΈΡ… ΠΈΠ½ΠΊΡƒΠ±Π°Ρ†ΠΈΠΈ с паклитаксСлом ΠΈ ΠΊΠΎΠ½ΡŠΡŽΠ³Π°Ρ‚Π°ΠΌΠΈ. ΠΠ°Ρ€ΡƒΡˆΠ΅Π½ΠΈΡ ΠΊΠ»Π΅Ρ‚ΠΎΡ‡Π½ΠΎΠ³ΠΎ Ρ†ΠΈΠΊΠ»Π° опрСдСляли с ΠΏΡ€ΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ΠΌ FACS β€” ΠΊΠ»Π΅Ρ‚ΠΎΡ‡Π½ΠΎΠ³ΠΎ сортСра. Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹: установлСно, Ρ‡Ρ‚ΠΎ ΠΊΠ»Π΅Ρ‚ΠΎΡ‡Π½Ρ‹Π΅ Π»ΠΈΠ½ΠΈΠΈ Π½Π΅ΠΌΠ΅Π»ΠΊΠΎΠΊΠ»Π΅Ρ‚ΠΎΡ‡Π½ΠΎΠ³ΠΎ Ρ€Π°ΠΊΠ° Π»Π΅Π³ΠΊΠΎΠ³ΠΎ A549 ΠΈ Calu-6 ΡΠΊΡΠΏΡ€Π΅ΡΡΠΈΡ€ΡƒΡŽΡ‚ SSTR2 ΠΈ SSTR5 мРНК. ΠžΡ‚ΠΌΠ΅Ρ‡Π΅Π½ΠΎ эффСктивноС Π΄ΠΎΠ·ΠΎ- ΠΈ врСмязависимоС ΡƒΠ³Π½Π΅Ρ‚Π΅Π½ΠΈΠ΅ роста ΠΊΠ»Π΅Ρ‚ΠΎΠΊ A549 ΠΈ Calu-6 паклитаксСлом ΠΈ ΠΊΠΎΠ½ΡŠΡŽΠ³Π°Ρ‚Π°ΠΌΠΈ. Для SSTR-Π½Π΅Π³Π°Ρ‚ΠΈΠ²Π½Ρ‹Ρ… фибробластов ΠΊΠΎΠ½ΡŠΡŽΠ³Π°Ρ‚Ρ‹ ΠΌΠ΅Π½Π΅Π΅ цитотоксичны, Ρ‡Π΅ΠΌ паклитаксСл. ΠšΠΎΠ½ΡŠΡŽΠ³Π°Ρ‚Ρ‹ ΠΈ паклитаксСл ΠΌΠΎΠ³ΡƒΡ‚ ΠΈΠ½Π΄ΡƒΡ†ΠΈΡ€ΠΎΠ²Π°Ρ‚ΡŒ ΠΏΠΎΠ²Ρ‹ΡˆΠ΅Π½ΠΈΠ΅ ΡΠΎΠΎΡ‚Π½ΠΎΡˆΠ΅Π½ΠΈΡ Ρ„Π°Π· G2 /M Π² ΠΊΠ»Π΅Ρ‚ΠΊΠ°Ρ… A549. Π’Ρ‹Π²ΠΎΠ΄Ρ‹: ΠΊΠΎΠ½ΡŠΡŽΠ³Π°Ρ‚Ρ‹ паклитаксСл-ΠΎΠΊΡ‚Ρ€Π΅ΠΎΡ‚ΠΈΠ΄Π° ΠΌΠΎΠ³ΡƒΡ‚ Π±Ρ‹Ρ‚ΡŒ ΠΈΡΠΏΠΎΠ»ΡŒΠ·ΠΎΠ²Π°Π½Ρ‹ ΠΊΠ°ΠΊ сСлСктивныС химиотСрапСвтичСскиС Π°Π³Π΅Π½Ρ‚Ρ‹ для воздСйствия Π½Π° Π½Π΅ΠΌΠ΅Π»ΠΊΠΎΠΊΠ»Π΅Ρ‚ΠΎΡ‡Π½Ρ‹ΠΉ Ρ€Π°ΠΊ Π»Π΅Π³ΠΊΠΎΠ³ΠΎ
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