Comprender el mundo. La valencia hermenéutica del binomio Lebenswelt (Husserl) e In-der-Welt-sein (Heidegger).

Sin resume

Seroprevalencia de hepatitis virales en pacientes programados para artroplastia de sustitución de cadera y rodilla

Se estudiaron 102 pacientes consecutivos propuestos para artoplastia de sustitución de cadera o rodilla entre julio de 1998 y mayo de 2000 para conocer la prevalencia de marcadores serológicos de los virus de la hepatitis B (VHB) y C (VHC), y su asociación con factores de riesgo o predictivos prequirúrgicos. La edad media fue de 70±6 años, con predominio femenino. La prevalencia de antígeno de superficie del VHB fue de 1,96%, la de anticuerpo anti-core del mismo virus fue del 26,47%, y no se observó ningún marcador positivo frente al VHC. Ningún factor de riesgo o predictivo estudiado presentó diferencias significativas según la positividad de los marcadores, excepto la hepatopatía previa. La cohorte de pacientes estudiados, representativa de los pacientes programados para esta cirugía en nuestro medio, no presenta un mayor riesgo de transmisión de hepatitis vírica, aunque sí mayor contacto con el VHB que otras poblaciones de menor edad.One hundred and two consecutive patients scheduled for hip or knee arthroplasty were studied from July 1998 to May 2000, to detect the prevalence of serologic markets of B (HBV) and C (HCV) hepatitis viruses, and its preoperative association with rink or predictive factors. Mean age was 70±6 years, and women predominated. Prevalence of HBV surface antigen was 1,96%, that of HBV anti-core antibody was 26,47%, and no positive markers were observed against HCV. None of variables evaluated as risk or predictive factors showed significant association with presence of serum markers, except previous liver disease. The studied group of patients, representative of the scheduled patients for total hip or knee arthroplasty in our area, does not suggest a higher risk of viral hepatitis transmission. However, a higher number of contacts with HBV than in younger populations have been observed in this group

Comprender el mundo. La valencia hermenéutica del binomio Lebenswelt (Husserl) e In-der-Welt-sein (Heidegger).

Sin resume

Cell biophysical stimuli in lobodopodium formation: a computer based approach

Different cell migration modes have been identified in 3D environments, e.g., modes incorporating lamellopodia or blebs. Recently, a new type of cellular migration has been investigated: lobopodia-based migration, which appears only in three-dimensional matrices under certain conditions. The cell creates a protrusion through which the nucleus slips, dividing the cell into two parts (front and rear) with different hydrostatic pressures. In this work, we elucidate the mechanical conditions that favour this type of migration. One of the hypotheses about this type of migration is that it depends on the mechanical properties of the extracellular matrix. That is, lobopodia-based migration is dependent on whether the extracellular matrix is linearly elastic or non-linearly elastic. To determine whether the mechanical properties of the extracellular matrix are crucial in the choice of cell migration mode and which mechanotransduction mechanism the cell might use, we develop a finite element model. From our simulations, we identify two different possible mechanotransduction mechanisms that could regulate the cell to switch from a lobopodial to a lamellipodial migration mode. The first relies on a differential pressure increase inside the cytoplasm while the cell contracts, and the second relies on a change in the fluid flow direction in non-linearly elastic extracellular matrices but not in linearly elastic matrices. The biphasic nature of the cell has been determined to mediate this mechanism and the different behaviours of cells in linearly elastic and non-linearly elastic matrices

Finite Element Simulation of the Deformation of a Cell Driven by Creeping Flow

The purpose of this work is to calculate the deformation undergone by a cell in function of its nucleus size and mechanical properties. The cell immersed in a fluid go through a variable section channel and it is deformed by fluid forces.Cell deformation into the channel causes changes at the fluid velocity profile. This fluid configuration change results in diferent normal and viscous forces around the cell. Due to strong correlation between cell deformation and fluid velocity profile, a fluidsolid interacción (FSI) is required

El metamorfismo de bajo grado en el Paleozoico del sector central de la Cordillera Ibérica

Se describe el metamorfismo de bajo grado en sus aspectos paragenéticos, intensidad y condiciones de las rocas paleozoicas del sector central de la Cordillera Ibérica

Gases Separation by ZSM-5 based Membranes

AbstractPresent work analyses the effect produced by the presence of ZSM-5 zeolite in an alumina tube upon the permeation rate of different gases (nitrogen, oxygen, carbon dioxide and normal-butane). A comparison between experimental data of permeation through the membrane with and without ZSM-5 zeolite was performed with an increase in the resistance to transport more evident for n-butane. Also the influence of temperature upon permeation has been analyzed

Vertical distribution of the macrofauna in polluted sediments from the harbour of Ceuta

Vertical distribution of the macrofauna and its relationship with physico-chemical parameters were studied in polluted sediments from the harbour of Ceuta. The samples were collected with cores (10 cm ˟ 17 cm ˟ 35 cm) by scuba divers. The following depths in the sediment column were included in the study: 0-2 cm, 2- 5 cm, 5-10 cm and more than 10 cm. The crustaceans Pariambus typicus Kröyer, 1844; Apseudes latreilli Milne-Edwards, 1820; Corophium runcicorne Della Valle, 1893; C. sextonae Crawford, 1937; the mollusc Parvicardium exiguum (Gmelin, 1791), and the polychaetes Pseudomalacoceros tridentata (Southern, 1914) and Exogone verrugera Cleparede, 1868 were found in the first 2 cm of the sediment, whereas the mollusc Loripes lacteus (L., 1758) and the polychaetes Platynereis dumerilii Audouin & Milne Edwards; 1833; Cirratulus cirratus (Muller; 1776) and Cirriformia tentaculata (Montagu; 1808) were dominant in deeper strata; and size increased with depth. A multivariate analysis showed that the percentage of silt and clays; the total organic matter; and especially; the maltenes/asphaltenes ratio; were the main factors affecting species' vertical distribution.Se ha estudiado la distribución vertical de la macrofauna y su relación con las variables fisicoquímicas de los sedimentos contaminados del puerto de Ceuta. La obtención de las muestras se llevó a cabo mediante buceo con escafandra autónoma y empleando instrumentos de muestreo tipo core (10 cm ˟ 17 cm ˟ 35 cm), diferenciándose las siguientes profundidades en la columna de sedimento: 0-2 cm, 2-5 cm, 5-10 cm y más de 10 cm. Los crustáceos Pariambus typicus Kröyer, 1844; Apseudes latreilli Milne-Edwards, 1820; Corophium runcicorne Della Valle, 1893; C. sextonae Crawford, 1937; el molusco Parvicardium exiguum (Gmelin, 1791) y los poliquetos Pseudomalacoceros tridentata (Southern, 1914) y Exogone verrugera Cleparede, 1868 se localizaron en los dos primeros centímetros de sedimento, mientras que el molusco Loripes lacteus (L., 1758) y los poliquetos Platynereis dumerilii Audouin y Milne-Edwards, 1833; Cirratulus cirratus (Muller, 1776) y Cirriformia tentaculata (Montagu, 1808) dominaron en los niveles más profundos, observándose el incremento en el tamaño de los individuos con el aumento de la profundidad. Los análisis multivariantes reflejaron que el porcentaje de pelitas, la materia orgánica total y, especialmente, la relación lípidos malténicos/lípidos asfalténicos, fueron los principales factores condicionantes de la distribución vertical de las especies en el sedimento.Instituto Español de Oceanografí

Versatilidad del colgajo safeno para la cobertura de los defectos de rodilla: presentación de 6 casos

Clásicamente las pérdidas de sustancia de la rodilla se resuelven mediante injertos, colgajos cutáneos o fasciocutáneos, o bien por colgajos musculares de gemelo interno o externo, según la localización y profundidad del defecto. El propósito del trabajo es destacar la creciente relevancia de los colgajos neurovaseularizados como el colgajo safeno en la rodilla, en especial para aquellos casos sin gran componente infeccioso, en los que prevalecerían las indicaciones de utilización de colgajos musculares. Presentamos 4 casos de cobertura de prótesis de rodila expuestas en la región de la tuberosidad tibial anterior y/o línea de sutura y otros 2 casos de defectos tras resección tumoral. Los casos han sido realizados durante los 3 últimos años y su seguimiento clínico es de 6 meses a 3 años. En todos los casos se resolvió el problema de cobertura.Traditionally, substance loss at the knee level is solved through skin grafts, cutaneous or fascio-cutaneous flaps or through medial o lateral gastrocnemius muscle flaps depeding on the location and deep of the defect. We highlight the increasing relevance of neurovasculariccd flaps, and specially in this region, of the saphenous flap, better in cases with minor infectious component, in which the indication would be muscular flaps. We present four clinical cases in which we used them to cover anterior tibial tuberosity and/or dehiscent of skin closure and collected during the 3 last years another two cases with cutaneous defect after tumoral resection. All have uneventful recovery. The follow-up period varied from 6 months to 3 years