Conformations of Linear DNA

We examine the conformations of a model for under- and overwound DNA. The molecule is represented as a cylindrically symmetric elastic string subjected to a stretching force and to constraints corresponding to a specification of the link number. We derive a fundamental relation between the Euler angles that describe the curve and the topological linking number. Analytical expressions for the spatial configurations of the molecule in the infinite- length limit were obtained. A unique configuraion minimizes the energy for a given set of physical conditions. An elastic model incorporating thermal fluctuations provides excellent agreement with experimental results on the plectonemic transition.Comment: 5 pages, RevTeX; 6 postscript figure

N=3 Warped Compactifications

Orientifolds with three-form flux provide some of the simplest string examples of warped compactification. In this paper we show that some models of this type have the unusual feature of D=4, N=3 spacetime supersymmetry. We discuss their construction and low energy physics. Although the local form of the moduli space is fully determined by supersymmetry, to find its global form requires a careful study of the BPS spectrum.Comment: 27 pages, v2: 32pp., RevTeX4, fixed factors, slightly improved sections 3D and 4B, v3: added referenc

Dynamical Kohn Anomaly in Surface Acoustic Wave Response in Quantum Hall Systems Near ν=1/2\nu = 1/2

The dynamical analog of the Kohn Anomaly image of the Fermi Surface is demonstrated for the response functions to the surface acoustic waves in Quantum Hall Systems near $\nu = 1/2$. Kinks appear in the velocity shift $Delta s/s$ and attenuation coefficient $\Gamma$. The effect is considerably enhanced under periodic modulation and should be observable.Comment: 5 pages, 2 figures, the published versio

The influence of community structure on crime news coverage: structural pluralism, ethnic diversity, and local crime news

This study examines patterns of local newspaper crime coverage in terms of the community structure model, which is derived from the research of Tichenor, Donohue, and Olien. A total of 32 metropolitan statistical areas and primary metropolitan statistical areas, classified into four different categories of community according to the structural characteristics of structural pluralism and ethnic diversity, were selected for inclusion in this study. Crime news reports from the major newspaper of each selected community were analyzed based on the types of crimes (violent crime vs. property crime). These data were then compared to FBI crime statistics. In terms of the results, ethnic diversity was found to be a more important factor than structural pluralism in explaining the high proportion of violent crime coverage and the lesser amount of reportage of property crimes, as well as the discrepancies between the newspaper crime reports and the FBI crime statistics

Modeling the R2* relaxivity of blood at 1.5 Tesla

BOLD (Blood Oxygenation Level Dependent) imaging is used in fMRI to show differences in activation of the brain based on the relative changes of the T2* (= 1/R2*) signal of the blood. However, quantification of blood oxygenation level based on the T2* signal has been hindered by the lack of a predictive model which accurately correlates the T2* signal to the oxygenation level of blood. The T2* signal decay in BOLD imaging is generated due to blood containing paramagnetic deoxyhemoglobin (in comparison to diamagnetic oxyhemoglobin). This generates local field inhomogeneities, which cause protons to experience different phase shifts, leading to dephasing and the MR signal decay. The blood T2* signal has been shown to decay with a complex behavior1, termed Non-Lorenztian, and thus is not adequately described by the traditional model of simplemono-exponential decay. Theoretical calculations show that diffusion narrowing substantially affects signal loss in our data. Over the past decade, several theoretical models have been proposed to describe this Non-Lorenztian behavior in the blood T2* signal in BOLD fMRI imaging. The goal of this project was to investigate different models which have been proposed over the years and determine a semi-phenomenological model for the T2* behaviorusing actual MR blood data

Prospects and constraints on utilization of Jatropha curcas seeds in animal feedstuff

Combined physical, chemical and biochemical methods were used to process virgin seed meal of Jatropha curcas L. into treated Jatropha Seed Meal (JSM). Graded levels (0, 5, 10, 15, 20 and 25%) JSM treated by the various methods was included in the test diets which were fed ad libitum to 360 albino rats for a month in a single factor design trial. The results revealed that feed intake was numerically highest (p > 0.05) for the rats on the 5 % treated JSM diet, while feed efficiency was highest (p > 0.05) for those on the 10 % treated JSM diets. Weight gain was significantly highest (p< 0.05) for the rats on 10 and 15 % treated JSM diets. Lowest survival rate (17%) was observed on treated JSM diet processed by boiling, roasting followed by fermenting. Biochemical indices measured on treated JSM based diets were comparable with those obtained on the conventional diet (p > 0.05) except for blood cholesterol level (p < 0.05) which was elevated with increasing treated JSM in diets. There were also no significant differences recorded on AST and ALP activities (p > 0.05) between the treatments. Haematological indices investigated including PCV, RBC, Hb were insignificantly influenced by the 5% dietary treated JSM compared with the control diet (p > 0.05) and there was non-significant effect of the dietary treatment on the WBC differential counts of lymphocytes, eosinophils, monocytes and neutrophils. It was established in this study that inclusion of 5% treated JSM in diets had no detrimental effect on albino rats. Further researches are in progress to investigate inclusion of the treated JSM in diets at levels higher than the 5% used in this study.Keywords: JSM, Cockerels, Performance, Biochemical and haematological parameter

Human muscle-derived cell populations isolated by differential adhesion rates: Phenotype and contribution to skeletal muscle regeneration in Mdx/SCID mice

Muscle-derived stem cells (MDSCs) isolated from murine skeletal tissue by the preplate method have displayed the capability to commit to the myogenic lineage and regenerate more efficiently than myoblasts in skeletal and cardiac muscle in murine Duchenne Muscular Dystrophy mice (mdx). However, until now, these studies have not been translated to human muscle cells. Here, we describe the isolation, by a preplate technique, of candidate human MDSCs, which exhibit myogenic and regenerative characteristics similar to their murine counterparts. Using the preplate isolation method, we compared cells that adhere faster to the flasks, preplate 2 (PP2), and cells that adhere slower, preplate 6 (PP6). The human PP6 cells express several markers of mesenchymal stem cells and are distinct from human PP2 (a myoblast-like population) based on their expression of CD146 and myogenic markers desmin and CD56. After transplantation to the gastrocnemius muscle of mdx/SCID mice, we observe significantly higher levels of PP6 cells participating in muscle regeneration as compared with the transplantation of PP2 cells. This study supports some previous findings related to mouse preplate cells, and also identifies some differences between mouse and human muscle preplate cells

Electrojet Estimates From Mesospheric Magnetic Field Measurements

The auroral electrojet is traditionally measured remotely with magnetometers on ground or in low Earth orbit (LEO). The sparse distribution of measurements, combined with a vertical distance of some 100 km to ground and typically >300 km to LEO satellites, means that smaller scale sizes can't be detected. Because of this, our understanding of the spatiotemporal characteristics of the electrojet is incomplete. Recent advances in measurement technology give hope of overcoming these limitations by multi-point remote detections of the magnetic field in the mesosphere, very close to the electrojet. We present a prediction of the magnitude of these disturbances, inferred from the spatiotemporal characteristics of magnetic field-aligned currents. We also discuss how Zeeman magnetic field sensors (Yee et al., 2021) onboard the Electrojet Zeeman Imaging Explorer satellites will be used to essentially image the equivalent current at unprecedented spatial resolution. The electrojet imaging is demonstrated by combining carefully simulated measurements with a spherical elementary current representation using a novel inversion scheme.publishedVersio