763 research outputs found
In vitro antifungal susceptibility of Cladophialophora carrionii, agent of human chromoblastomycosis
Dyonic Integrable Models
A class of non abelian affine Toda models arising from the axial gauged
two-loop WZW model is presented. Their zero curvature representation is
constructed in terms of a graded Kac-Moody algebra. It is shown that the
discrete multivacua structure of the potential together with non abelian nature
of the zero grade subalgebra allows soliton solutions with non trivial electric
and topological charges.
The dressing transformation is employed to explicitly construct one and two
soliton solutions and their bound states in terms of the tau functions. A
discussion of the classical spectra of such solutions and the time delays are
given in detail.Comment: Latex 30 pages, corrected some typo
Andrographolide Inhibits PI3K/AKT-Dependent NOX2 and iNOS Expression Protecting Mice against Hypoxia/Ischemia-Induced Oxidative Brain Injury
This study aimed to explore the mechanisms by which andrographolide protects against hypoxia-induced oxidative/nitrosative brain injury provoked by cerebral ischemic/reperfusion (CI/R) injury in mice. Hypoxia in vitro was modeled using oxygen-glucose deprivation (OGD) followed by reoxygenation of BV-2 microglial cells. Our results showed that treatment of mice that have undergone CI/R injury with andrographolide (10-100 mu g/kg, i.v.) at 1 h after hypoxia ameliorated CI/R-induced oxidative/nitrosative stress, brain infarction, and neurological deficits in the mice, and enhanced their survival rate. CI/R induced a remarkable production in the mouse brains of reactive oxygen species (ROS) and a significant increase in protein nitrosylation; this primarily resulted from enhanced expression of NADPH oxidase 2 (NOX2), inducible nitric oxide synthase (iNOS), and the infiltration of CD11b cells due to activation of nuclear factor-kappa B (NF-kappa B) and hypoxia-inducible factor 1-alpha (HIF-1 alpha). All these changes were significantly diminished by andrographolide. In BV-2 cells, OGD induced ROS and nitric oxide production by upregulating NOX2 and iNOS via the phosphatidylinositol-3-kinase (PI3K)/AKT-dependent NF-kappa B and HIF-1 alpha pathways, and these changes were suppressed by andrographolide and LY294002. Our results indicate that andrographolide reduces NOX2 and iNOS expression possibly by impairing PI3K/AKT-dependent NF-kappa B and HIF-1 alpha activation. This compromises microglial activation, which then, in turn, mediates andrographolide's protective effect in the CI/R mice
Efficiency improvement of a ground coupled heat pump system from energy management
The installed capacity of an air conditioning system is usually higher than the average cooling or heating
demand along the year. So, most of the time, the system is working under its actual capacity. In this
contribution, we study the way to improve the efficiency of a ground coupled heat pump air conditioning
system by adapting its produced thermal energy to the actual thermal demand. For this purpose, an air
conditioning system composed by a ground coupled heat pump and a central fan coil linked to an office
located in a cooling dominated area was simulated, and a new management strategy aiming to diminish
electrical consumption was developed under the basic constraint that comfort requirements are kept.
This strategy takes advantage of the possibility of managing the air flow in the fan, the water mass flows
in the internal and external hydraulic systems, and the set point temperature in the heat pump to
achieve this objective. The electrical consumption of the system is calculated for the new management
strategy and compared with the results obtained for a conventional one, resulting in estimated energy
savings around 30%This work has been supported by the Spanish Government under projects "Modelado y simulacion de sistemas energeticos complejos" (2005 Ramon y Cajal program), "Modelado, simulacion y validacion experimental de la transferencia de calor en el entorno de la edificacion" (ENE2008-0059/CON). A. Sala is grateful to the financial support of grants DPI2008-06731-c02-01 (Spanish Government), and Generalitat Valenciana Prometeo/2008/088.Pardo García, N.; Montero Reguera, ÁE.; Sala Piqueras, A.; Martos Torres, J.; Urchueguía Schölzel, JF. (2011). Efficiency improvement of a ground coupled heat pump system from energy management. Applied Thermal Engineering. 31(2):391-398. https://doi.org/10.1016/j.applthermaleng.2010.09.016S39139831
Lepton Mixing Matrix in Standard Model Extended by One Sterile Neutrino
We consider the simplest extension of the standard electroweak model by one
sterile neutrino that allows for neutrino masses and mixing. We find that its
leptonic sector contains much less free physical parameters than previously
realized. In addition to the two neutrino masses, the lepton mixing matrix in
charged current interactions involves (n-1) free physical mixing angles for n
generations. The mixing matrix in neutral current interactions of neutrinos is
completely fixed by the two masses. Both interactions conserve CP. We
illustrate the phenomenological implications of the model by vacuum neutrino
oscillations, tritium beta decay and neutrinoless double beta decay. It turns
out that, due to the revealed specific structure in its mixing matrix, the
model with any n generations cannot accommodate simultaneously the data by
KamLAND, K2K and CHOOZ.Comment: 14 pages, no figures; version 2: (1) added a short paragraph at the
end of subsec 2.2 to record the counting of physical parameters for any
numbers of generations and sterile neutrinos for completeness; (2) added a
note in ref list, item [18] to quote and comment on an earlier work; (3)
added the second paper to ref list, item [17]; (4) fixed typo
Multicharged Dyonic Integrable Models
We introduce and study new integrable models of A_n^{(1)}-Non-Abelian Toda
type which admit U(1)\otimes U(1) charged topological solitons. They correspond
to the symmetry breaking SU(n+1) \to SU(2)\otimes SU(2)\otimes U(1)^{n-2} and
are conjectured to describe charged dyonic domain walls of N=1 SU(n+1) SUSY
gauge theory in large n limit.
It is shown that this family of relativistic IMs corresponds to the first
negative grade q={-1} member of a dyonic hierarchy of generalized cKP type. The
explicit relation between the 1-soliton solutions (and the conserved charges as
well) of the IMs of grades q=-1 and q=2 is found. The properties of the IMs
corresponding to more general symmetry breaking SU(n+1) \to SU(2)^{\otimes
p}\otimes U(1)^{n-p} as well as IM with global SU(2) symmetries are discussed.Comment: 48pages, latex, v2. typos in eqns. (1.7) and (3.20) corrected, small
improvements in subsection 2.2, new reference added;v3. improvements in text
of Sect. 1,2 and 6; new Sect 7 and new refs. added; version to appear in
Nucl. Phys.
Charged lepton electric dipole moments with the localized leptons and the new Higgs doublet in the two Higgs doublet model
We study the lepton electric dipole moments in the split fermion scenario, in
the two Higgs doublet model, where the new Higgs scalars are localized around
the origin in the extra dimension, with the help of the localizer field. We
observe that the numerical value of the electron (muon, tau) electric dipole
moment is at the order of the magnitude of 10^{-31} (10^{-24}, 10^{-22}) (e-cm)
and this quantity is sensitive the new Higgs localization in the extra
dimension.Comment: 20 pages, 7 figure
Two lectures on color superconductivity
The first lecture provides an introduction to the physics of color
superconductivity in cold dense quark matter. The main color superconducting
phases are briefly described and their properties are listed. The second
lecture covers recent developments in studies of color superconducting phases
in neutral and beta-equilibrated matter. The properties of gapless color
superconducting phases are discussed.Comment: 56 pages, 9 figures. Minor corrections and references added. Lectures
delivered at the IARD 2004 conference, Saas Fee, Switzerland, June 12 - 19,
2004, and at the Helmholtz International Summer School and Workshop on Hot
points in Astrophysics and Cosmology, JINR, Dubna, Russia, August 2 - 13,
200
Measurements of J/psi Decays into 2(pi+pi-)eta and 3(pi+pi-)eta
Based on a sample of 5.8X 10^7 J/psi events taken with the BESII detector,
the branching fractions of J/psi--> 2(pi+pi-)eta and J/psi-->3(pi+pi-)eta are
measured for the first time to be (2.26+-0.08+-0.27)X10^{-3} and
(7.24+-0.96+-1.11)X10^{-4}, respectively.Comment: 11 pages, 6 figure
BESII Detector Simulation
A Monte Carlo program based on Geant3 has been developed for BESII detector
simulation. The organization of the program is outlined, and the digitization
procedure for simulating the response of various sub-detectors is described.
Comparisons with data show that the performance of the program is generally
satisfactory.Comment: 17 pages, 14 figures, uses elsart.cls, to be submitted to NIM
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