Structural adjustment and the contemporary sub-Saharan African city

Although it has been suggested that structural adjustment policies have slowed Third World urban growth and have stimulated a spatial deconcentration of economic activity, this paper argues that African cities continue to grow and mainly through peri-urban development. This investment comes mainly from domestic sources and migrants' remittances, and tends to he in consumption rather than production. Reasons include cultural factors lack of confidence in the national economy and in the state's long-term economic objectives, an increasing demand for housing, improvements in intraurban transport, and a desire to spread investment risk among a range of alternatives including housing

Rare earth geochemistry of Arenig cherts from the Ballantrae Ophiolite and Leadhills Imbricate Zone, southern Scotland: implications for origin and significance to the Caledonian Orongeny

Rare earth element (REE) data from low to mid-Arenig cherts are used to test competing models for the early Ordovician evolution of the Laurentian margin in the northern British Isles. Cherts from the Ballantrae Ophiolite Complex have chondrite-normalized REE patterns typical of continental margin settings with LREE enrichment, a slight negative Eu(anom) and shale and chondrite-normalized La/Yb values of 0.97-1.41 and 7.78-11.4 respectively. This pattern, together with a large positive chondrite-normalized Ce(anom) (1.44-1.70), is virtually identical to that found in radiolarian chert of the Gascoyne Abyssal Plain, in the Timor Sea. Cherts from the Raven Gill Formation within the Leadhills Imbricate Zone, Northern Belt, Southern Uplands have typical continental margin REE patterns, chondrite-normalized Ce(anom) (0.9-1.21) and Eu(anom) (0.61-0.79) values indicating that they formed closer to the continental margin than those from Ballantrae. Shale and chondrite-normalized and La/Yb values of 0.95-1.27 and 4.92-13.88 respectively confirm this interpretation. It is concluded that the Ballantrae ophiolite formed in a rifted-arc basin above a northwards dipping, intra-oceanic subduction zone. The modest depth of burial of the Raven Gill Formation precludes it being part of a marginal basin which was subsequently trapped as the Ballantrae Ophiolite was obducted in the late Arenig. The Arenig rocks of the Leadhills Imbricate Zone represent an allochthonous terrane accreted to the western extension of the Midland Valley in Ireland in pre-Caradoc times. Here it formed the basement to the Southern Uplands basin. Palaeontological evidence places this basin adjacent to Pomeroy, Co. Tyrone in the early Caradoc. Sinistral strike-slip faulting, from the late Ashgill transported the Southern Uplands Terrance to its present location, a distance of less than 250 km

The architecture of cancellous bone in the hindlimb of moa (Aves: Dinornithiformes), with implications for stance and gait

The extinct, flightless moa of New Zealand included some of the largest birds to have existed and possessed many distinguishing pelvic and hindlimb osteological features. These features may have influenced stance and gait in moa compared with extant birds. One means of assessing locomotor biomechanics, particularly for extinct species, is quantitative analysis of the architecture of cancellous bone, since this architecture is adapted to suit its mechanical environment with high sensitivity. This study investigated the three-dimensional architecture of cancellous bone in the femur, tibiotarsus and fibula of three moa species: Dinornis robustus, Pachyornis elephantopus and Megalapteryx didinus. Using computed tomographic X-ray scanning and previously developed fabric analysis techniques, the spatial variation in cancellous bone fabric patterns in moa was found to be largely comparable with that previously reported for extant birds, particularly large species. Moa hence likely used postures and kinematics similar to those employed by large extant bird species, but this interpretation is tentative on account of relatively small sample sizes. A point of major difference between moa and extant birds concerns the diaphyses; cancellous bone invades the medullary cavity in both groups, but the invasion is far more extensive in moa. Combined with previous assessments of cortical geometry, this further paints a picture of at least some moa species possessing very robust limb bones, for which a convincing explanation remains to be determine

The effect of relative hypotension on 30-day mortality in older people receiving emergency care

Research has observed increased mortality among older people attending the emergency department (ED) who had systolic pressure > 7 mmHg lower than baseline primary care values. This study aimed to (1) assess feasibility of identifying this ‘relative hypotension’ using readily available ED data, (2) externally validate the 7 mmHg threshold, and (3) refine a threshold for clinically important relative hypotension. A single-centre retrospective cohort study linked year 2019 data for ED attendances by people aged over 64 to hospital discharge vital signs within the previous 18 months. Frailty and comorbidity scores were calculated. Previous discharge (‘baseline’) vital signs were subtracted from initial ED values to give individuals’ relative change. Cox regression analysis compared relative hypotension > 7 mmHg with mean time to mortality censored at 30 days. The relative hypotension threshold was refined using a fully adjusted risk tool formed of logistic regression models. Receiver operating characteristics were compared to NEWS2 models with and without incorporation of relative systolic. 5136 (16%) of 32,548 ED attendances were linkable with recent discharge vital signs. Relative hypotension > 7 mmHg was associated with increased 30-day mortality (HR 1.98; 95% CI 1.66–2.35). The adjusted risk tool (AUC: 0.69; sensitivity: 0.61; specificity: 0.68) estimated each 1 mmHg relative hypotension to increase 30-day mortality by 2% (OR 1.02; 95% CI 1.02–1.02). 30-day mortality prediction was marginally better with NEWS2 (AUC: 0.73; sensitivity: 0.59; specificity: 0.78) and NEWS2 + relative systolic (AUC: 0.74; sensitivity: 0.63; specificity: 0.75). Comparison of ED vital signs with recent discharge observations was feasible for 16% individuals. The association of relative hypotension > 7 mmHg with 30-day mortality was externally validated. Indeed, any relative hypotension appeared to increase risk, but model characteristics were poor. These findings are limited to the context of older people with recent hospital admissions

Does a Computer have an Arrow of Time?

In [Sch05a], it is argued that Boltzmann's intuition, that the psychological arrow of time is necessarily aligned with the thermodynamic arrow, is correct. Schulman gives an explicit physical mechanism for this connection, based on the brain being representable as a computer, together with certain thermodynamic properties of computational processes. [Haw94] presents similar, if briefer, arguments. The purpose of this paper is to critically examine the support for the link between thermodynamics and an arrow of time for computers. The principal arguments put forward by Schulman and Hawking will be shown to fail. It will be shown that any computational process that can take place in an entropy increasing universe, can equally take place in an entropy decreasing universe. This conclusion does not automatically imply a psychological arrow can run counter to the thermodynamic arrow. Some alternative possible explana- tions for the alignment of the two arrows will be briefly discussed.Comment: 31 pages, no figures, publication versio

Effect of simplicity and attractiveness on route selection for different journey types

This study investigated the effects of six attributes, associated with simplicity or attractiveness, on route preference for three pedestrian journey types (everyday, leisure and tourist). Using stated choice preference experiments with computer generated scenes, participants were asked to choose one of a pair of routes showing either two levels of the same attribute (experiment 1) or different attributes (experiment 2). Contrary to predictions, vegetation was the most influential for both everyday and leisure journeys, and land use ranked much lower than expected in both cases. Turns ranked higher than decision points for everyday journeys as predicted, but the positions of both were lowered by initially unranked attributes. As anticipated, points of interest were most important for tourist trips, with the initially unranked attributes having less influence. This is the first time so many attributes have been compared directly, providing new information about the importance of the attributes for different journeys. © 2014 Springer International Publishing

A Mathematical Model of Liver Cell Aggregation In Vitro

The behavior of mammalian cells within three-dimensional structures is an area of intense biological research and underpins the efforts of tissue engineers to regenerate human tissues for clinical applications. In the particular case of hepatocytes (liver cells), the formation of spheroidal multicellular aggregates has been shown to improve cell viability and functionality compared to traditional monolayer culture techniques. We propose a simple mathematical model for the early stages of this aggregation process, when cell clusters form on the surface of the extracellular matrix (ECM) layer on which they are seeded. We focus on interactions between the cells and the viscoelastic ECM substrate. Governing equations for the cells, culture medium, and ECM are derived using the principles of mass and momentum balance. The model is then reduced to a system of four partial differential equations, which are investigated analytically and numerically. The model predicts that provided cells are seeded at a suitable density, aggregates with clearly defined boundaries and a spatially uniform cell density on the interior will form. While the mechanical properties of the ECM do not appear to have a significant effect, strong cell-ECM interactions can inhibit, or possibly prevent, the formation of aggregates. The paper concludes with a discussion of our key findings and suggestions for future work

Search for W' bosons decaying to an electron and a neutrino with the D0 detector

This Letter describes the search for a new heavy charged gauge boson W' decaying into an electron and a neutrino. The data were collected with the D0 detector at the Fermilab Tevatron proton-antiproton Collider at a center-of-mass energy of 1.96 TeV, and correspond to an integrated luminosity of about 1 inverse femtobarn. Lacking any significant excess in the data in comparison with known processes, an upper limit is set on the production cross section times branching fraction, and a W' boson with mass below 1.00 TeV can be excluded at the 95% C.L., assuming standard-model-like couplings to fermions. This result significantly improves upon previous limits, and is the most stringent to date.Comment: submitted to Phys. Rev. Let

Evidence of Color Coherence Effects in W+jets Events from ppbar Collisions at sqrt(s) = 1.8 TeV

We report the results of a study of color coherence effects in ppbar collisions based on data collected by the D0 detector during the 1994-1995 run of the Fermilab Tevatron Collider, at a center of mass energy sqrt(s) = 1.8 TeV. Initial-to-final state color interference effects are studied by examining particle distribution patterns in events with a W boson and at least one jet. The data are compared to Monte Carlo simulations with different color coherence implementations and to an analytic modified-leading-logarithm perturbative calculation based on the local parton-hadron duality hypothesis.Comment: 13 pages, 6 figures. Submitted to Physics Letters

Search for a scalar or vector particle decaying into Zgamma in ppbar collisions at sqrt(s) = 1.96 TeV

We present a search for a narrow scalar or vector resonance decaying into Zgamma with a subsequent Z decay into a pair of electrons or muons. The data for this search were collected with the D0 detector at the Fermilab Tevatron ppbar collider at a center of mass energy sqrt(s) = 1.96 TeV. Using 1.1 (1.0) fb-1 of data, we observe 49 (50) candidate events in the electron (muon) channel, in good agreement with the standard model prediction. From the combination of both channels, we derive 95% C.L. upper limits on the cross section times branching fraction (sigma x B) into Zgamma. These limits range from 0.19 (0.20) pb for a scalar (vector) resonance mass of 600 GeV/c^2 to 2.5 (3.1) pb for a mass of 140 GeV/c^2.Comment: Published by Phys. Lett.