2,953 research outputs found

    Relationship between kinetic and kinematic measures of the countermovement jump and national weightlifting performance

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    Purpose The association between vertical jump and weightlifting performance have been well established often using discrete performance measures such as jump height or peak power which provides little insight into temporal strategies. The purpose of this investigation was to identify currently unassessed temporal countermovement jump metrics and their reliability and relationship to national weightlifting performance. Methods A total of 42 national weightlifting athletes (n = 30 females and 12 males), were recruited for this study. Countermovement jump was measured using a force plate following a national and international competition. Vertical ground reaction force and time data were analyzed using a custom script where temporal metrics relating to specific phases of the jump were extracted. Snatch, Clean and Jerk and Total weightlifting performance was obtained following each competition. Reliability of jump metrics were determined using coefficient of variation and interclass correlation coefficient. A Spearman’s Rho, non-parametric bivariate correlation was used to determine the relationship between the jump metrics and weightlifting performance. Results From a total of 15 metrics, 13 were deemed reliable, with propulsive impulse showing the greatest level of reliability. Correlational analysis showed strong to very strong (r = 0.676–0.817) relationships between all absolute measures of weightlifting performance and propulsive impulse for both women and men. Conclusion This novel finding suggests that practitioners may wish to use propulsive impulse as it may provide more insight into changes of force capabilities following training. Additionally, it may also be used as a talent identification tool given its strong relationship to performance

    What e-patients want from the doctor-patient relationship: content analysis of posts on discussion boards.

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    People with long-term conditions are encouraged to take control and ownership of managing their condition. Interactions between health care staff and patients become partnerships with sharing of expertise. This has changed the doctor-patient relationship and the division of roles and responsibilities that traditionally existed, but what each party expects from the other may not always be clear. Information that people with long-term conditions share on Internet discussion boards can provide useful insights into their expectations of health care staff. This paper reports on a small study about the expectations that people with a long-term condition (diabetes) have of their doctors using information gleaned from Internet discussion boards

    Behavioral Approaches for Infant Pain Relief

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    Infants experience a host of painful medical procedures including heel sticks, venipuncture, and immunizations. Historically, little attention was given to infant pain management due to misconceived myths and beliefs about the experience and long-term effects of pain in infants. Recent data suggest that there are both short- and long-term negative repercussions associated with unmanaged infant pain. In response, a number of non-pharmacological approaches have been developed to provide infants with pain relief associated with medical events. This paper will review these behavioral approaches including positioning, parent training, distraction, sucrose, and skin-to-skin contact. Recommendations for best practices will be provided and future direction for infant pain management will be outlined

    Psychological Approaches to Acute Pediatric Pain Management

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    Children endure numerous acute painful events, most of which occur within the medical arena. For instance, by the time a child reaches the age of 6, the child will have experienced approximately 30 immunization injections (Centers for Disease Control and Prevention, 2008). Grounded in the Gate Control Theory (Melzack & Wall, 1965), psychological methods of pain management have focused on anxiety and pain management via behavioral means. In addition, ample research has been devoted to how best to prepare children and their parents for upcoming painful or distress-provoking procedures (e.g., surgery, hospitalization, injection). This paper will review the preparation literature, which details how to inform and arm children and their parents for impending procedures and will highlight the psychological pain management literature which includes distraction, cognitive behavioral therapy, and additional promising interventions

    Phase II study of docetaxel in combination with epirubicin and protracted venous infusion 5-fluorouracil (ETF) in patients with recurrent or metastatic breast cancer. A Yorkshire breast cancer research group study

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    This study was originally designed as a phase I/II study, with a dose escalation of docetaxel in combination with epirubicin 50 mg m⁻² and 5-fluorouracil (5-FU) 200 mg m⁻² day⁻¹. However, as dose escalation was not possible, the study is reported as a phase II study of the combination to assess response and toxicity. A total of 51 patients with locally advanced or metastatic breast cancer were treated on this phase II study, with doses of docetaxel 50 mg m⁻², epirubicin 50 mg m⁻² and infusional 5-FU 200 mg m⁻² day⁻¹ for 21 days. The main toxicity of this combination was neutropenia with 89% of patients having grade 3 and 4 neutropenia, and 39% of patients experiencing febrile neutropenia. Nonhaematological toxicity was mild. The overall response rate in the assessable patients was 64%, with median progression-free survival of 38 weeks, and median survival of 70 weeks. The ETF regimen was found to be toxic, and it was not possible to escalate the dose of docetaxel above the first dose level. This regimen has therefore not been taken any further, but as a development of this a new study is ongoing, combining 3-weekly epirubicin, weekly docetaxel and capecitabine, days 1-14

    The Color Dipole Picture of low-x DIS: Model-Independent and Model-Dependent Results

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    We present a detailed examination of the color-dipole picture (CDP) of low-xx deep inelastic scattering. We discriminate model-independent results, not depending on a specific parameterization of the dipole cross section, from model-dependent ones. The model-independent results include the ratio of the longitudinal to the transverse photoabsorption cross section at large Q2Q^2, or equivalently the ratio of the longitudinal to the unpolarized proton structure function, FL(x,Q2)=0.27F2(x,Q2)F_L (x,Q^2)=0.27 F_2 (x, Q^2), as well as the low-xx scaling behavior of the total photoabsorption cross section σγp(W2,Q2)=σγp(η(W2,Q2))\sigma_{\gamma^*p} (W^2, Q^2)=\sigma_{\gamma^*p} (\eta (W^2, Q^2)) as log(1/η(W2,Q2))\log (1 / \eta (W^2, Q^2)) for η(W2,Q2)<1\eta (W^2, Q^2) <1, and as 1/η(W2,Q2)1/\eta (W^2, Q^2) for η(W2,Q2)1\eta (W^2, Q^2) \gg 1. Here, η(W2,Q2)\eta (W^2, Q^2) denotes the low-xx scaling variable, η(W2,Q2)=(Q2+m02)/Λsat2(W2)\eta (W^2, Q^2)=(Q^2 + m^2_0) / \Lambda^2_{sat} (W^2) with Λsat2(W2)\Lambda^2_{sat} (W^2) being the saturation scale. The model-independent analysis also implies limW2,Q2fixedσγp(W2,Q2)/σγp(W2)1\lim\limits_{W^2\rightarrow\infty, Q^2 {\rm fixed}} \sigma_{\gamma^*p} (W^2, Q^2) / \sigma_{\gamma p} (W^2) \rightarrow 1 at any Q2Q^2 for asymptotically large energy, WW. Consistency with pQCD evolution determines the underlying gluon distribution and the numerical value of C2=0.29C_2 = 0.29 in the expression for the saturation scale, Λ2(W2)(W2)C2\Lambda^2 (W^2) \sim (W^2)^{C_2}. In the model-dependent analysis, by restricting the mass of the actively contributing qqˉq \bar q fluctuations by an energy-dependent upper bound, we extend the validity of the color-dipole picture to xQ2/W20.1x \cong Q^2 / W^2 \le 0.1. The theoretical results agree with the world data on DIS for 0.036GeV2Q2316GeV20.036 {\rm GeV}^2 \le Q^2 \le 316 {\rm GeV}^2.Comment: 77 pages, 30 figure

    Daphnias: from the individual based model to the large population equation

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    The class of deterministic 'Daphnia' models treated by Diekmann et al. (J Math Biol 61: 277-318, 2010) has a long history going back to Nisbet and Gurney (Theor Pop Biol 23: 114-135, 1983) and Diekmann et al. (Nieuw Archief voor Wiskunde 4: 82-109, 1984). In this note, we formulate the individual based models (IBM) supposedly underlying those deterministic models. The models treat the interaction between a general size-structured consumer population ('Daphnia') and an unstructured resource ('algae'). The discrete, size and age-structured Daphnia population changes through births and deaths of its individuals and throught their aging and growth. The birth and death rates depend on the sizes of the individuals and on the concentration of the algae. The latter is supposed to be a continuous variable with a deterministic dynamics that depends on the Daphnia population. In this model setting we prove that when the Daphnia population is large, the stochastic differential equation describing the IBM can be approximated by the delay equation featured in (Diekmann et al., l.c.)

    Evaluating ‘enhancing pragmatic language skills for young children with social communication impairments’ (E-PLAYS): protocol for a feasibility randomised controlled trial study

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    Background: A number of children experience difficulties with social communication and this has long-term deleterious effects on their mental health, social development and education. The proposal presented in this article describes a feasibility study for a trial to test an intervention (‘E-PLAYS’) aimed at supporting children with social communication impairments. E-PLAYS harnesses technology in the form of a novel computer game in order to develop collaborative and communication skills. Preliminary studies by the authors show that when E-PLAYS was administered by the research team, children with social communication impairments showed improvements on communication test scores and on observed collaborative behaviours. The study described here is a pragmatic trial to test the application of E-PLAYS delivered by NHS speech and language therapists together with schools. Methods: This protocol outlines a two-arm feasibility cluster-randomised controlled trial of the E-PLAYS intervention with treatment as usual control arm, with randomisation at the level of the speech and language therapist. The aim of this study is to ascertain whether it will be feasible to progress to running a full-scale definitive trial to test the effectiveness of E-PLAYS in an NHS setting. Data relating to recruitment and retention, the appropriateness of outcomes and the acceptability of E-PLAYS to participants will be collected. Speech and language therapists will select suitable children (ages 4–7 years old) from their caseloads and deliver either the E-PLAYS intervention (experimental group) or treatment as usual (control group). Assessments will include blinded language measures and observations, non-blinded teacher-reported measures of peer relations and classroom behaviour and parent-reported use of resources and quality of life. There will also be a qualitative process evaluation. Discussion: The findings of this study will inform the decision as to whether to progress to a full-scale definitive randomised controlled trial to test the effectiveness of E-PLAYS when delivered by speech and language therapists and teaching assistants within schools. The use of technology in game form is a novel approach in an area where there are currently few available interventions
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