Multiway vortex valve system Patent

Multiple vortex amplifier system as fluid valv

Single-node orbit analsyis with radiation heat transfer only

The steady-state temperature of a single node which dissipates energy by radiation only is discussed for a nontime varying thermal environment. Relationships are developed to illustrate how shields can be utilized to represent a louver system. A computer program is presented which can assess periodic temperature characteristics of a single node in a time varying thermal environment having energy dissipation by radiation only. The computer program performs thermal orbital analysis for five combinations of plate, shields, and louvers

Role of Membrane GM1 on Early Neuronal Membrane Actions of Aβ During Onset of Alzheimer\u27s Disease

The ability of beta-amyloid peptide (Aβ) to disrupt the plasma membrane through formation of pores and membrane breakage has been previously described. However, the molecular determinants for these effects are largely unknown. In this study, we examined if the association and subsequent membrane perforation induced by Aβ was dependent on GM1levels. Pretreatment of hippocampal neurons with D-PDMP decreased GM1 and Aβ clustering at the membrane (Aβ fluorescent-punctas/20 μm, control = 16.2 ± 1.1 vs. D-PDMP = 6.4 ± 0.4, p \u3c 0.001). Interestingly, membrane perforation with Aβ occurred with a slower time course when the GM1 content was diminished (time to establish perforated configuration (TEPC) (min): control = 7.8 ± 2 vs. low GM1 = 12.1 ± 0.5, p \u3c 0.01), suggesting that the presence of GM1 in the membrane can modulate the distribution and the membrane perforation by Aβ. On the other hand, increasing GM1 facilitated the membrane perforation (TEPC: control = 7.8 ± 2 vs. GM1 = 6.2 ± 1 min, p \u3c 0.05). Additionally, using Cholera Toxin Subunit-B (CTB) to block the interaction of Aβ with GM1 attenuated membrane perforation significantly. Furthermore, pretreatment with CTB decreased the membrane association of Aβ (fluorescent-punctas/20 μm, Aβ: control = 14.8 ± 2.5 vs. CTB = 8 ± 1.4, p \u3c 0.05), suggesting that GM1 also plays a role in both association of Aβ with the membrane and in perforation. In addition, blockade of the Aβ association with CTB inhibited synaptotoxicity. Taken together, our results strongly suggest that membrane lipid composition can affect the ability of Aβ to associate and subsequently perforate the plasma membrane thereby modulating its neurotoxicity in hippocampal neurons

Sizing-tube-fin space radiators

Temperature and size considerations of the tube fin space radiator were characterized by charts and equations. An approach of accurately assessing rejection capability commensurate with a phase A/B level output is reviewed. A computer program, based on Mackey's equations, is also presented which sizes the rejection area for a given thermal load. The program also handles the flow and thermal considerations of the film coefficient

System analysis of a piston steam engine employing the uniflow principle, a study in optimized performance

Results are reported which were obtained from a mathematical model of a generalized piston steam engine configuration employing the uniflow principal. The model accounted for the effects of clearance volume, compression work, and release volume. A simple solution is presented which characterizes optimum performance of the steam engine, based on miles per gallon. Development of the mathematical model is presented. The relationship between efficiency and miles per gallon is developed. An approach to steam car analysis and design is presented which has purpose rather than lucky hopefulness. A practical engine design is proposed which correlates to the definition of the type engine used. This engine integrates several system components into the engine structure. All conclusions relate to the classical Rankine Cycle

The Level of NMDA Receptor in the Membrane Modulates Amyloid-β Association and Perforation

Alzheimer’s disease is a neurodegenerative disorder that affects mostly the elderly. The main histopathological markers are the senile plaques formed by amyloid-β peptide (Aβ) aggregates that can perforate the plasma membrane of cells, increasing the intracellular calcium levels and releasing synaptic vesicles that finally lead to a delayed synaptic failure. Several membrane proteins and lipids interact with Aβ affecting its toxicity in neurons. Here, we focus on NMDA receptors (NMDARs) as proteins that could be modulating the association and neurotoxic perforation induced by Aβ on the plasma membrane. In fact, our results showed that decreasing NMDARs, using enzymatic or siRNA approaches, increased the association of Aβ to the neurons. Furthermore, overexpression of NMDARs also resulted in an enhanced association between NMDA and Aβ. Functionally, the reduction in membrane NMDARs augmented the process of membrane perforation. On the other hand, overexpressing NMDARs had a protective effect because Aβ was now unable to cause membrane perforation, suggesting a complex relationship between Aβ and NMDARs. Because previous studies have recognized that Aβ oligomers are able to increase membrane permeability and produce amyloid pores, the present study supports the conclusion that NMDARs play a critical protective role on Aβ actions in hippocampal neurons. These results could explain the lack of correlation between brain Aβ burden and clinically observed dementia

“46 YEARS REMOVED, 400 YEARS BEHIND: THE MISCONCEIVED EFFECTS OF INTEGRATION 2000 ON THE AFRICAN-AMERICAN COLLEGIATE”

“The university system, supposedly committed to diverse ideals and higher consciousness, has in reality become a white-centralized institution of exclusion.

Spring 1968

Massachusetts Turf and Lawn Grass CouncilBetter Turf Through Research and Education Contents: Wetting Agents by Stuart Denton (page 3) Deflation in Amateur Prize Value (5) Mark of the Industry Today is Professional Tree Care (6) Stockbridge Graduate Appointed Head of Winged Foot (8) Soil Testing Doubles in 10 Years by George Enfield (9) 1968 University of Massachusetts Annual Fine Turf Conference (12) Roots, Selectors of Plant Nutrients by J.B. Hanson (16) Soil Amendments by David Peoples (19) Sex Attractant for Fall Armyworm (23) New Bluegrass Getting Attention (23) New Variety of Bluegrass Now Available (24

Ultra-White BaSO4 Paint and Film with Remarkable Radiative Cooling Performance

Radiative cooling is a passive cooling technology that offers great promises to reduce space cooling cost, combat the urban island effect, and alleviate the global warming. To achieve passive daytime radiative cooling, current state-of-the-art solutions often utilize complicated multilayer structures or a reflective metal layer, limiting their applications in many fields. Attempts have been made to achieve passive daytime radiative cooling with single-layer paints, but they often require a thick coating or show partial daytime cooling. In this work, we experimentally demonstrate remarkable full-daytime subambient cooling performance with both BaSO4 nanoparticle films and BaSO4 nanocomposite paints. BaSO4 has a high electron band gap for low solar absorptance and phonon resonance at 9 μm for high sky window emissivity. With an appropriate particle size and a broad particle size distribution, the BaSO4 nanoparticle film reaches an ultrahigh solar reflectance of 97.6% and a high sky window emissivity of 0.96. During field tests, the BaSO4 film stays more than 4.5 °C below ambient temperature or achieves an average cooling power of 117 W/m2. The BaSO4-acrylic paint is developed with a 60% volume concentration to enhance the reliability in outdoor applications, achieving a solar reflectance of 98.1% and a sky window emissivity of 0.95. Field tests indicate similar cooling performance to the BaSO4 films. Overall, our BaSO4-acrylic paint shows a standard figure of merit of 0.77, which is among the highest of radiative cooling solutions while providing great reliability, convenient paint form, ease of use, and compatibility with the commercial paint fabrication process