2,388 research outputs found
First record of a pregnant female little sleeper shark Somniosus rostratus (Risso, 1826) on the Spanish Mediterranean coast
This present paper records the catch of a pregnant female little sleeper shark Somniosus rostratus (Risso, 1826) in the waters of the Catalan continental slope (Spain). Eight embryos were found inside the animal. This is the first record of a pregnant female S. rostratus in the western Mediterranean.Se señala la captura de una hembra de tiburón dormilón Somniosus rostratus (Risso, 1826) frente a las costas de Cataluña (España). Dicho ejemplar estaba grávido y era portador de ocho embriones. éste es el primer registro de una hembra preñada de esta especie en el Mediterráneo occidental.Instituto Español de Oceanografí
Breakdown of a conservation law in incommensurate systems
We show that invariance properties of the Lagrangian of an incommensurate
system, as described by the Frenkel Kontorova model, imply the existence of a
generalized angular momentum which is an integral of motion if the system
remains floating. The behavior of this quantity can therefore monitor the
character of the system as floating (when it is conserved) or locked (when it
is not). We find that, during the dynamics, the non-linear couplings of our
model cause parametric phonon excitations which lead to the appearance of
Umklapp terms and to a sudden deviation of the generalized momentum from a
constant value, signalling a dynamical transition from a floating to a pinned
state. We point out that this transition is related but does not coincide with
the onset of sliding friction which can take place when the system is still
floating.Comment: 7 pages, 6 figures, typed with RevTex, submitted to Phys. Rev. E
Replaced 27-03-2001: changes to text, minor revision of figure
Observations of rotationally resolved C3 in translucent sight lines
The rotationally resolved spectrum of the A ^1Pi_u <- X ^1Sigma^+_g 000-000
transition of C3, centered at 4051.6A, has been observed along 10 translucent
lines of sight. To interpret these spectra, a new method for the determination
of column densities and analysis of excitation profiles involving the
simulation and fitting of observed spectra has been developed. The populations
of lower rotational levels (J<14) in C3 are best fit by thermal distributions
that are consistent with the kinetic temperatures determined from the
excitation profile of C2. Just as in the case of C2, higher rotational levels
(J>14) of C3 show increased nonthermal population distributions in clouds which
have been determined to have total gas densities below ~500 cm-3.Comment: 12 pages, 4 figures, accepted for publication in The Astrophysical
Journa
Dynamic State Estimation for Load Bus Protection on Inverter-Interfaced Microgrids
Inverter-interfaced microgrids results in challenges when designing
protection systems. Traditional time-overcurrent, admittance, and differential
protection methods are unsuitable on account of lack of fault current,
excessively short lines, or a prohibitive number of protective devices needing
to be installed. Current practice is to force all inverters to shut down during
fault conditions, weakening resilience and reducing reliability. Dynamic state
estimation (DSE), which has been explored for both line protection and load bus
protection before, is a potential solution to these challenges to create widely
utilizable, highly reliable protection systems. However, it has only been
tested for load protection with ideal voltage sources, which do not capture the
short-circuit behavior of inverter-interfaced generation, notably low fault
current and unbalanced output voltage. This paper aims to extend the
state-of-the-art on DSE load protection: the performance of DSE during
short-circuit conditions with a grid-forming inverter with current-limiting
behavior during fault conditions is investigated.Comment: 5 pages. 3 figures. 1 table
Anomalous pinning behavior in an incommensurate two-chain model of friction
Pinning phenomena in an incommensurate two-chain model of friction are
studied numerically. The pinning effect due to the breaking of analyticity
exists in the present model. The pinning behavior is, however, quite different
from that for the breaking of analyticity state of the Frenkel-Kontorova model.
When the elasticity of chains or the strength of interchain interaction is
changed, pinning force and maximum static frictional force show anomalously
complicated behavior accompanied by a successive phase transition and they
vanish completely under certain conditions.Comment: RevTex, 9 pages, 19 figures, to appear in Phys. Rev. B58 No.23(1998
Captopril reduces cardiac inflammatory markers in spontaneously hypertensive rats by inactivation of NF-kB
<p>Abstract</p> <p>Background</p> <p>Captopril is an angiotensin-converting enzyme (ACE) inhibitor widely used in the treatment of arterial hypertension and cardiovascular diseases. Our objective was to study whether captopril is able to attenuate the cardiac inflammatory process associated with arterial hypertension.</p> <p>Methods</p> <p>Left ventricle mRNA expression and plasma levels of pro-inflammatory (interleukin-1β (IL-1β) and IL-6) and anti-inflammatory (IL-10) cytokines, were measured in spontaneously hypertensive rats (SHR) and their control normotensive, Wistar-Kyoto (WKY) rats, with or without a 12-week treatment with captopril (80 mg/Kg/day; n = six animals per group). To understand the mechanisms involved in the effect of captopril, mRNA expression of ACE, angiotensin II type I receptor (AT1R) and p22phox (a subunit of NADPH oxidase), as well as NF-κB activation and expression, were measured in the left ventricle of these animals.</p> <p>Results</p> <p>In SHR, the observed increases in blood pressures, heart rate, left ventricle relative weight, plasma levels and cardiac mRNA expression of IL-1β and IL-6, as well as the reductions in the plasma levels and in the cardiac mRNA expression of IL-10, were reversed after the treatment with captopril. Moreover, the mRNA expressions of ACE, AT1R and p22phox, which were enhanced in the left ventricle of SHR, were reduced to normal values after captopril treatment. Finally, SHR presented an elevated cardiac mRNA expression and activation of the transcription nuclear factor, NF-κB, accompanied by a reduced expression of its inhibitor, IκB; captopril administration corrected the observed changes in all these parameters.</p> <p>Conclusion</p> <p>These findings show that captopril decreases the inflammation process in the left ventricle of hypertensive rats and suggest that NF-κB-driven inflammatory reactivity might be responsible for this effect through an inactivation of NF-κB-dependent pro-inflammatory factors.</p
Friction and wear of human hair fibres
An experimental study of the tribological properties of hair fibres is reported, and the effect of surface treatment on the evolution of friction and wear during sliding. Specifically, orthogonally crossed fibre/fibre contacts under a compressive normal load over a series of 10,000 cycle studies are investigated. Reciprocating sliding at a velocity of 0.4 mm/s−1, over a track length of 0.8 mm, was performed at 18oC and 40-50% relative humidity. Hair fibres retaining their natural sebum were studied, as well as those stripped of their sebum via hexane cleaning, and hair fibres conditioned using a commercially available product. Surface topography modifications resulting from wear were imaged using scanning electron microscopy and quantified using white light interferometry. Hair fibres that presented sebum or conditioned product at the fibre/fibre junction exhibited initial coefficients of friction at least 25% lower than those that were cleaned with hexane. Coefficients of friction were observed to depend on the directionality of sliding for hexane cleaned hair fibres after sufficient wear cycles that cuticle lifting was present, typically on the order 1,000 cycles. Cuticle flattening was observed for fibre/fibre junctions exposed to 10 mN compressive normal loads, whereas loads of 100 mN introduced substantial cuticle wear and fibre damage
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Secreted IgM deficiency leads to increased BCR signaling that results in abnormal splenic B cell development.
Mice lacking secreted IgM (sIgM -/-) antibodies display abnormal splenic B cell development, which results in increased marginal zone and decreased follicular B cell numbers. However, the mechanism by which sIgM exhibit this effect is unknown. Here, we demonstrate that B cells in sIgM -/- mice display increased B cell receptor (BCR) signaling as judged by increased levels of phosphorylated Bruton's tyrosine kinase (pBtk), phosphorylated Spleen tyrosine kinase (pSyk), and nuclear receptor Nur77. Low dosage treatment with the pBtk inhibitor Ibrutinib reversed the altered B cell development in the spleen of sIgM -/- mice, suggesting that sIgM regulate splenic B cell differentiation by decreasing BCR signaling. Mechanistically, we show that B cells, which express BCRs specific to hen egg lysozyme (HEL) display diminished responsiveness to HEL stimulation in presence of soluble anti-HEL IgM antibodies. Our data identify sIgM as negative regulators of BCR signaling and suggest that they can act as decoy receptors for self-antigens that are recognized by membrane bound BCRs
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