Submillimeter observations of solar limb-brightening in the total solar eclipse of 31 July 1981

Eight flights of the Kuiper Airborne Observatory (KAO) were devoted to solar observation. The successful observation of a total solar eclipse was accomplished. The observations were made simultaneously at 30, 50, 100, and 200 microns. The successful adaptation of the KAO for solar observations thus provided the most detailed data to date in this spectral band. The results from a preliminary analysis of the KAO data are summarized: (1) the 200 micron limb is extended about 3 arc sec above the 30 micron limb, indicating the prescence of cool dense material up to the altitudes of spicules; (2) strong radial darkening of the quiet sun intensity profile appeared at 200 microns, probably an indication that hot material in the low chromosphere is recessed into vertical magnetic flux tubes embedded in a cooler nonmagnetic substrate, which obscures the heated material approaching the limb; (3) active regions were observed to undergo a strong increase in contrast above the quiet sun background at wave lengths of 100 microns and longer; and (4) the moon was mapped for use as a photometric standard for determining the absolute intensity of the sun in all four wavelength bands

Extreme limb profiles of the sun at far-infrared and submillimeter wavelengths

Thirty, 50, 100, and 200 microns solar limb intensity profiles determined with arcsecond resolution from airborne observations of the occultation of the solar limb during the total eclipse of 1981 July 31 are presented. Two points of particular importance emerge: (1) the longer-wavelength (100 and 200 micron) limbs are significantly brighter than disk center. At 200 microns the extreme limb is about 1.22 times the brightness of disk center. This is consistent with the 6000 K temperature-plateau structure of the model chromospheres of Vernazza, Avrett, and Loeser (1973, Ap. J., 184, 605; 1981; Ap. J. Suppl., 45, 635;) and (2) the longer wavelength limbs are extended significantly further above the visible limb than Vernazza, Avrett, and Loeser predict. These results provide a strong basis for modeling of the solar chromosphere free from the assumption of gravitational-hydrostatic equilibrium

Submillimeter extensions of the solar limb determined from observations of the total eclipse of 1981 July 31

First results are presented of observations of a lunar occultation of the solar limb made from the Kuiper Airborne Observatory in the 30 micrometr, 50 micrometer, 100 micrometer, and 200 micrometer continuum during the total solar eclipse of 1981 July 31. The solar limb was extended at the longer wavelengths up to 1000 km higher than predicted from smooth plane-parallel chromospheric models. Results at both second and third contact show the infrared limb extensions to be approximately 0".8, 1"5, 2".5 and 3".0 above the visible limb in the observed bands, respectively. A possible interpretation proposes chromospheric fine structure inhomogeneities of greater density than presently incorporated in models of the middle chromosphere

Clonal expansion within pneumococcal serotype 6C after use of seven-valent vaccine

Streptococcus pneumoniae causes invasive infections, primarily at the extremes of life. A seven-valent conjugate vaccine (PCV7) is used to protect against invasive pneumococcal disease in children. Within three years of PCV7 introduction, we observed a fourfold increase in serotype 6C carriage, predominantly due to a single clone. We determined the whole-genome sequences of nineteen S. pneumoniae serotype 6C isolates, from both carriage (n = 15) and disease (n = 4) states, to investigate the emergence of serotype 6C in our population, focusing on a single multi-locus sequence type (MLST) clonal complex 395 (CC395). A phylogenetic network was constructed to identify different lineages, followed by analysis of variability in gene sets and sequences. Serotype 6C isolates from this single geographical site fell into four broad phylogenetically distinct lineages. Variation was seen in the 6C capsular locus and in sequences of genes encoding surface proteins. The largest clonal complex was characterised by the presence of lantibiotic synthesis locus. In our population, the 6C capsular locus has been introduced into multiple lineages by independent capsular switching events. However, rapid clonal expansion has occurred within a single MLST clonal complex. Worryingly, plasticity exists within current and potential vaccine-associated loci, a consideration for future vaccine use, target selection and design

Dynamical Solution of the On-Line Minority Game

We solve the dynamics of the on-line minority game, with general types of decision noise, using generating functional techniques a la De Dominicis and the temporal regularization procedure of Bedeaux et al. The result is a macroscopic dynamical theory in the form of closed equations for correlation- and response functions defined via an effective continuous-time single-trader process, which are exact in both the ergodic and in the non-ergodic regime of the minority game. Our solution also explains why, although one cannot formally truncate the Kramers-Moyal expansion of the process after the Fokker-Planck term, upon doing so one still finds the correct solution, that the previously proposed diffusion matrices for the Fokker-Planck term are incomplete, and how previously proposed approximations of the market volatility can be traced back to ergodicity assumptions.Comment: 25 pages LaTeX, no figure

Advanced secondary power system for transport aircraft

A concept for an advanced aircraft power system was identified that uses 20-kHz, 440-V, sin-wave power distribution. This system was integrated with an electrically powered flight control system and with other aircraft systems requiring secondary power. The resulting all-electric secondary power configuration reduced the empty weight of a modern 200-passenger, twin-engine transport by 10 percent and the mission fuel by 9 percent

Superflares on Ordinary Solar-Type Stars

Short duration flares are well known to occur on cool main-sequence stars as well as on many types of `exotic' stars. Ordinary main-sequence stars are usually pictured as being static on time scales of millions or billions of years. Our sun has occasional flares involving up to $\sim 10^{31}$ ergs which produce optical brightenings too small in amplitude to be detected in disk-integrated brightness. However, we identify nine cases of superflares involving $10^{33}$ to $10^{38}$ ergs on normal solar-type stars. That is, these stars are on or near the main-sequence, are of spectral class from F8 to G8, are single (or in very wide binaries), are not rapid rotators, and are not exceedingly young in age. This class of stars includes many those recently discovered to have planets as well as our own Sun, and the consequences for any life on surrounding planets could be profound. For the case of the Sun, historical records suggest that no superflares have occurred in the last two millennia.Comment: 16 pages, accepted for publication in Ap

Death or survival from invasive pneumococcal disease in Scotland: associations with serogroups and multilocus sequence types

We describe associations between death from invasive pneumococcal disease (IPD) and particular serogroups and sequence types (STs) determined by multilocus sequence typing (MLST) using data from Scotland. All IPD episodes where blood or cerebrospinal fluid (CSF) culture isolates were referred to the Scottish Haemophilus, Legionella, Meningococcal and Pneumococcal Reference Laboratory (SHLMPRL) from January 1992 to February 2007 were matched to death certification records by the General Register Office for Scotland. This represented 5959 patients. The median number of IPD cases in Scotland each year was 292. Deaths, from any cause, within 30 days of pneumococcal culture from blood or CSF were considered to have IPD as a contributing factor. Eight hundred and thirty-three patients died within 30 days of culture of Streptococcus pneumoniae from blood or CSF [13.95%; 95% confidence interval (13.10, 14.80)]. The highest death rates were in patients over the age of 75. Serotyping data exist for all years but MLST data were only available from 2001 onward. The risk ratio of dying from infection due to particular serogroups or STs compared to dying from IPD due to all other serogroups or STs was calculated. Fisher's exact test with Bonferroni adjustment for multiple testing was used. Age adjustment was accomplished using the Cochran-Mantel-Haenszel test and 95% confidence intervals were reported. Serogroups 3, 11 and 16 have increased probability of causing fatal IPD in Scotland while serogroup 1 IPD has a reduced probability of causing death. None of the 20 most common STs were significantly associated with death within 30 days of pneumococcal culture, after age adjustment. We conclude that there is a stronger association between a fatal outcome and pneumococcal capsular serogroup than there is between a fatal outcome and ST

Identifying risk factors for L'Hermitte's sign after IMRT for head and neck cancer.

BACKGROUND L’Hermitte’s sign (LS) after chemoradiotherapy for head and neck cancer appears related to higher spinal cord doses. IMRT plans limit spinal cord dose, but the incidence of LS remains high. METHODS 117 patients treated with TomoTherapy™ between 2008 and 2015 prospectively completed a side-effect questionnaire (VoxTox Trial Registration: UK CRN ID 13716). Baseline patient and treatment data were collected. Radiotherapy plans were analysed; mean and maximum spinal cord dose and volumes receiving 10, 20, 30 and 40 Gy were recorded. Dose variation across the cord was examined. These data were included in a logistic regression model. RESULTS 42 patients (35.9%) reported LS symptoms. Concurrent weekly cisplatin did not increase LS risk (p = 0.70, OR = 1.23 {95%CI 0.51 – 2.34}). Of 13 diabetic participants (9 taking metformin), only 1 developed LS (p = 0.025, OR = 0.13 {95%CI 0.051 – 3.27}). A refined binary logistic regression model showed that patients receiving unilateral radiation (p = 0.019, OR = 2.06 {95%CI 0.15 – 0.84}) were more likely to develop LS. Higher V40Gy (p = 0.047, OR = 1.06 {95%CI 1.00 – 1.12}), and younger age (mean age 56.6 vs 59.7, p = 0.060, OR = 0.96 {95%CI 0.92 – 1.00}) were associated with elevated risk of LS, with borderline significance. CONCLUSIONS In this cohort, concomitant cisplatin did not increase risk, and LS incidence was lower in diabetic patients. Patient age and dose gradients across the spinal cord may be important factors