Health-care district management information system plan: Review of operations analysis activities during calendar year 1975 and plan for continued research and analysis activities

Operations research activities developed to identify the information required to manage both the efficiency and effectiveness of the Veterans Administration (VA) health services as these services relate to individual patient care are reported. The clinical concerns and management functions that determine this information requirement are discussed conceptually. Investigations of existing VA data for useful management information are recorded, and a diagnostic index is provided. The age-specific characteristics of diseases and lengths of stay are explored, and recommendations for future analysis activities are articulated. The effect of the introduction of new technology to health care is also discussed

Chemokine-induced secretion of gelatinase B in primary human monocytes

Chemokines help control normal leukocyte trafficking as well as their infiltration into tissues during acute and chronic inflammation. Matrix metalloproteinases (MMPs) help support the extravasation and infiltration of leukocytes through limited proteolysis of basement membranes and matrix material. The effect of the chemokines RANTES/CCL5, MCP-1/CCL and SDF-1 /CXCL12 on secretion of the matrix metalloproteinase B and its endogenous inhibitor TIMP-1 was studied. RANTES/CCL5 and SDF-1/CXCL12 were found to induce MMP-9 secretion in primary human monocytes while TIMP-1 secretion was not affected. RANTES/CCL5 effects were mediated through CCR1 because the CCR1 antagonist BX471 was found to effectively block RANTES/CCL5-induced MMP-9 secretion

Chiral Spin Textures of Strongly Interacting Particles in Quantum Dots

We probe for statistical and Coulomb induced spin textures among the low-lying states of repulsively-interacting particles confined to potentials that are both rotationally and time-reversal invariant. In particular, we focus on two-dimensional quantum dots and employ configuration-interaction techniques to directly compute the correlated many-body eigenstates of the system. We produce spatial maps of the single-particle charge and spin density and verify the annular structure of the charge density and the rotational invariance of the spin field. We further compute two-point spin correlations to determine the correlated structure of a single component of the spin vector field. In addition, we compute three-point spin correlation functions to uncover chiral structures. We present evidence for both chiral and quasi-topological spin textures within energetically degenerate subspaces in the three- and four-particle system.Comment: 13 pages, 17 figures, 1 tabl

Influence of convective transport on tropospheric ozone and its precursors in a chemistry-climate model

The impact of convection on tropospheric O₃ and its precursors has been examined in a coupled chemistry-climate model. There are two ways that convection affects O₃. First, convection affects O₃ by vertical mixing of O₃ itself. Convection lifts lower tropospheric air to regions where the O₃ lifetime is longer, whilst mass-balance subsidence mixes O₃-rich upper tropospheric (UT) air downwards to regions where the O₃ lifetime is shorter. This tends to decrease UT O₃ and the overall tropospheric column of O₃. Secondly, convection affects O₃ by vertical mixing of O₃ precursors. This affects O₃ chemical production and destruction. Convection transports isoprene and its degradation products to the UT where they interact with lightning NO_x to produce PAN, at the expense of NO_x. In our model, we find that convection reduces UT NO_x through this mechanism; convective down-mixing also flattens our imposed profile of lightning emissions, further reducing UT NO_x. Over tropical land, which has large lightning NO_x emissions in the UT, we find convective lofting of NO_x from surface sources appears relatively unimportant. Despite UT NO_x decreases, UT O₃ production increases as a result of UT HO_x increases driven by isoprene oxidation chemistry. However, UT O₃ tends to decrease, as the effect of convective overturning of O₃ itself dominates over changes in O₃ chemistry. Convective transport also reduces UT O₃ in the mid-latitudes resulting in a 13% decrease in the global tropospheric O₃ burden. These results contrast with an earlier study that uses a model of similar chemical complexity. Differences in convection schemes as well as chemistry schemes – in particular isoprene-driven changes are the most likely causes of such discrepancies. Further modelling studies are needed to constrain this uncertainty range

Relating Physical Observables in QCD without Scale-Scheme Ambiguity

We discuss the St\"uckelberg-Peterman extended renormalization group equations in perturbative QCD, which express the invariance of physical observables under renormalization-scale and scheme-parameter transformations. We introduce a universal coupling function that covers all possible choices of scale and scheme. Any perturbative series in QCD is shown to be equivalent to a particular point in this function. This function can be computed from a set of first-order differential equations involving the extended beta functions. We propose the use of these evolution equations instead of perturbative series for numerical evaluation of physical observables. This formalism is free of scale-scheme ambiguity and allows a reliable error analysis of higher-order corrections. It also provides a precise definition for $\Lambda_{\overline{\rm MS}}$ as the pole in the associated 't Hooft scheme. A concrete application to $R(e^+e^- \to {\rm hadrons})$ is presented.Comment: Plain TEX, 4 figures (available upon request), 22 pages, DOE/ER/40322-17

Fabrication of free-standing ordered fluorescent polymer nanofibres by electrospinning

The authors are grateful to the Engineering and Physical Sciences Research Council for financial support.We demonstrate a static fabrication approach to make free-standing ordered arrays of fluorescent nanofibres through control of the transverse electrospinning field. The alignment and the density of the nanofibre arrays are optimised by careful design of both the source and collector electrode geometries which can control the transverse electric field over the full path of the jet. In doing so, we fabricate suspended fluorescent nanofibres with an aspect ratio of 10(4), and with a substantially increased density and order parameter (by a factor of similar to 10 compared to random deposition). Electrostatic modelling suggests that the field distribution of the component is the main contribution to the ordering between the plates. This method offers increased efficiency for the creation of ordered fibres collected over a small area and the characterisation of their photoluminescent properties.Publisher PDFPeer reviewe

Crucial Dependence of ``Precarious'' and ``Autonomous'' phi^4s Upon the Normal-ordering Mass

Using the Gaussian wave-functional approach with the normal-ordering renormalization prescription, we show that for the (3+1)-dimensional massive lambda phi^4 theory, ``precarious'' and ``autonomous'' phi^4s can exist if and only if the normal-ordering mass is equal to the classical masses at the symmetrc and asymmetric vacua, respectively.Comment: 6 pages, no figures, Revtex file, accepted for publication in Mod. Phys. Lett.

Origin of Tidal Dissipation in Jupiter: II. the Value of Q

The process of tidal dissipation inside Jupiter is not yet understood. Its tidal quality factor ($Q$) is inferred to lie between $10^5$ and $10^6$. We examine effects of inertial-modes on tidal dissipation in a neutrally bouyant, core-less, uniformly rotating planet. The rate of dissipation caused by resonantly excited inertial-modes depends on the following three parameters: how well they are coupled to the tidal potential, how strongly they are dissipated (by the turbulent viscosity), and how densely distributed they are in frequency. We find that as a function of tidal frequency, the $Q$ value exhibits large fluctuations, with its maximum value set by the group of inertial-modes that have a typical offset from an exact resonance of order their turbulent damping rates. In our model, inertial-modes shed their tidally acquired energy very close to the surface within a narrow latitudinal zone (the 'singularity belt'), and the tidal luminosity escapes freely out of the planet. Strength of coupling between the tidal potential and inertial-modes is sensitive to the presence of density discontinuities inside Jupiter. In the case of a discreet density jump (as may be caused by the transition between metallic and molecular hydrogen), we find a time-averaged $Q \sim 10^7$. Even though it remains unclear whether tidal dissipation due to resonant inertial-modes is the correct answer to the problem, it is impressive that our simple treatment here already leads to three to five orders of magnitude stronger damping than that from the equilibrium tide. Moreover, our conclusions are not affected by the presence of a small solid core, a different prescription for the turbulent viscosity, or nonlinear mode coupling, but they depend critically on the static stability in the upper atmosphere of Jupiter.Comment: 27 pages, incl. 11 figures, ApJ in print, expanded discussions (nonlinearity, radiative envelope