311 research outputs found
Kinetic modeling of Nernst effect in magnetized hohlraums
We present nanosecond time-scale Vlasov-Fokker-Planck-Maxwell modeling of magnetized plasma transport and dynamics in a hohlraum with an applied external magnetic field, under conditions similar to recent experiments. Self-consistent modeling of the kinetic electron momentum equation allows for a complete treatment of the heat flow equation and Ohm's law, including Nernst advection of magnetic fields. In addition to showing the prevalence of nonlocal behavior, we demonstrate that effects such as anomalous heat flow are induced by inverse bremsstrahlung heating. We show magnetic field amplification up to a factor of 3 from Nernst compression into the hohlraum wall. The magnetic field is also expelled towards the hohlraum axis due to Nernst advection faster than frozen-in flux would suggest. Nonlocality contributes to the heat flow towards the hohlraum axis and results in an augmented Nernst advection mechanism that is included self-consistently through kinetic modeling
A Randomised, Cross-Over, Placebo-Controlled Study of Aloe vera in Patients with Irritable Bowel Syndrome: Effects on Patient Quality of Life
Background. Irritable bowel syndrome (IBS) is a
chronic, difficult to treat condition. The efficacy of
Aloe vera in treating IBS symptoms is not yet
proven. The purpose of this study was to determine if Aloe
vera is effective in improving quality of life.
Methods. A multicentre, randomised, double-blind,
cross-over placebo controlled study design. Patients were
randomised to Aloe vera, wash-out, placebo or
placebo, washout, Aloe vera. Each preparation
(60 mL) was taken orally twice a day. Patient quality of
life was measured using the Gastrointestinal Symptoms Rating
Score, Irritable Bowel Syndrome Quality of Life, EuroQol and the
Short-Form-12 at baseline and treatment periods 1 and 2.
Results. A total of 110 patients were randomised,
but only 47 completed all questionnaires and both study arms.
Statistical analysis showed no difference between the placebo and
Aloe vera treatment in quality of life.
Discussion. This study was unable to show that Aloe
vera was superior to placebo in improving quality of
life. Drop outs and other confounding factors may have impacted on
the power of the study to detect a clinically important
difference. Conclusion. This study failed to find
Aloe vera superior to placebo in improving
quality of life proven Irritable Bowel Syndrome patients
VSOP and Ground-based VLBI Imaging of the TeV Blazar Markarian 421 at Multiple Epochs
We present thirty VLBI images of the TeV blazar Markarian 421 (1101+384) at
fifteen epochs spanning the time range from 1994 to 1997, and at six different
frequencies from 2.3 to 43 GHz. The imaged observations include a
high-resolution 5 GHz VLBI Space Observatory Programme (VSOP) observation with
the HALCA satellite on 1997 November 14; full-track VLBA observations from 1994
April, 1996 November, and 1997 May at frequencies between 5 and 43 GHz; six
epochs of VLBA snapshot observations at frequencies between 2 and 15 GHz from
Radio Reference Frame studies; and five geodetic VLBI observations at 2 and 8
GHz from the archive of the Washington VLBI Correlator Facility located at the
U.S. Naval Observatory. The dense time coverage of the images allows us to
unambiguously track components in the parsec-scale jet over the observed time
range. We measure the speeds of three inner jet components located between 0.5
and 5 mas from the core (0.3 to 3 pc projected linear distance) to be 0.19 +/-
0.27, 0.30 +/- 0.07, and -0.07 +/- 0.07 c (H_{0}=65 km s^{-1} Mpc^{-1}). If the
sole 43 GHz image is excluded, all measured speeds are consistent with no
motion. These speeds differ from tentative superluminal speeds measured by
Zhang & B\aa\aa th from three epochs of data from the early 1980's. Possible
interpretations of these subluminal speeds in terms of the high Doppler factor
demanded by the TeV variability of this source are discussed.Comment: 18 pages, including 7 figures, emulateapj.sty, accepted by The
Astrophysical Journal; modified text describing Radio Reference Frame
observation
Vlasov-Fokker-Planck simulations of fast-electron transport with hydrodynamic plasma response
Published versio
Geodetic VLBI Observations of EGRET Blazars
We present VLBI observations of the EGRET quasars 0202+149, CTA 26, and
1606+106, as well as additional analysis of VLBI observations of 1156+295
presented in Piner & Kingham (1997b). We have produced 8 and 2 GHz VLBI images
at 11 epochs, 8 epochs, and 12 epochs, spanning the years 1989 to 1996, of
0202+149, CTA 26, and 1606+106 respectively. The VLBI data have been taken from
the Washington VLBI correlator's geodetic database. We have measured the
apparent velocities of the jet components and find that CTA 26 and 1606+106 are
superluminal sources, with average apparent speeds of 8.9 and 2.9 h^{-1}c
respectively (H_{0}=100h km s^{-1} Mpc^{-1}, q_{0}=0.5). The components in
0202+149 are stationary, and we identify this source as a compact F double.
These sources all have apparently bent jets, and we detected non-radial motion
of components in CTA 26 and 1156+295. We have not yet detected any components
emerging subsequent to the gamma-ray flares in CTA 26, 1156+295, and 1606+106,
and we derive lower limits on the ejection times of any such components. The
misalignment angle distribution of the EGRET sources is compared to the
distribution for blazars as a whole, and we find that EGRET sources belong
preferentially to neither the aligned nor the misaligned population. We also
compare the average values for the apparent velocities and Doppler beaming
factors for the EGRET and non-EGRET blazars, and find no significant
differences. We thus find no indication, within the measurement errors, that
EGRET blazars are any more strongly beamed than their counterparts which have
not been detected in gamma-rays.Comment: 47 pages, including 13 figures; accepted for publication in the
Astrophysical Journa
Laryngeal transplantation in minipigs: vascular, myologic and functional outcomes
There is no effective way of replacing all the functions of the larynx in those requiring laryngectomy. Regenerative medicine offers promise, but cannot presently deliver implants with functioning neuromuscular units. A single well-documented laryngeal transplant in man was a qualified success, but more information is required before clinical trials may be proposed. We studied the early response of the larynx to laryngeal transplantation between 17 pairs of NIH minipigs full matched at the MHC2 locus. Following iterative technical improvements, pigs had good swallowing and a patent airway at 1 week. No significant changes in mucosal blood flux were observed compared with pre-operative measurements. Changes in muscle morphology and fibre phenotype were observed in transplant muscles retrieved after 7 days: the levels of fast and slow myosin heavy chain (MyHC) protein were reduced and embryonic MyHC was up regulated consistent with denervation induced atrophy. At 1 week laryngeal transplantation can result in good swallowing, and is not associated with clinical evidence of ischemia-reperfusion injury in MHC-matched pigs
Key Aspects of Health Policy Development to Improve Surgical Services in Uganda
Recently, surgical services have been gaining greater attention as an integral part of public health in low-income countries due to the significant volume and burden of surgical conditions, growing evidence of the cost-effectiveness of surgical intervention, and global disparities in surgical care. Nonetheless, there has been limited discussion of the key aspects of health policy related to surgical services in low-income countries. Uganda, like other low-income sub-Saharan African countries, bears a heavy burden of surgical conditions with low surgical output in health facilities and significant unmet need for surgical care. To address this lack of adequate surgical services in Uganda, a diverse group of local stakeholders met in Kampala, Uganda, in May 2008 to develop a roadmap of key policy actions that would improve surgical services at the national level. The group identified a list of health policy priorities to improve surgical services in Uganda. The priorities were classified into three areas: (1) human resources, (2) health systems, and (3) research and advocacy. This article is a critical discussion of these health policy priorities with references to recent literature. This was the first such multidisciplinary meeting in Uganda with a focus on surgical services and its output may have relevance to health policy development in other low-income countries planning to improve delivery of surgical services
- …