Universal out-of-equilibrium Transport in Kondo-correlated quantum dots: Renormalized dual Fermions on the Keldysh contour

The nonlinear conductance of semiconductor heterostructures and single molecule devices exhibiting Kondo physics has recently attracted attention. We address the observed sample dependence of the measured steady state transport coefficients by considering additional electronic contributions in the effective low-energy model underlying these experiments that are absent in particle-hole symmetric setups. A novel version of the superperturbation theory of Hafermann et al. in terms of dual fermions is developed, which correctly captures the low-temperature behavior. We compare our results with the measured transport coefficients.Comment: 5 pages, 2 figure

Climate model simulation of winter warming and summer cooling following the 1991 Mount Pinatubo volcanic eruption

We simulate climate change for the 2-year period following the eruption of Mount Pinatubo in the Philippines on June 15, 1991, with the ECHAM4 general circulation model (GCM). The model was forced by realistic aerosol spatial-time distributions and spectral radiative characteristics calculated using Stratospheric Aerosol, and Gas Experiment II extinctions and Upper Atmosphere Research Satellite-retrieved effective radii. We calculate statistical ensembles of GCM simulations with and without volcanic aerosols for 2 years after the eruption for three different sea surface temperatures (SSTs): climatological SST, El Nino-type SST of 1991-1993, and La Nina-type SST of 1984-1986. We performed detailed comparisons of calculated fields with observations, We analyzed the atmospheric response to Pinatubo radiative forcing and the ability of the GCM to reproduce it with different SSTs. The temperature of the tropical lower stratosphere increased by 4 K because of aerosol absorption of terrestrial longwave and solar near-infrared radiation. The heating is larger than observed, but that is because in this simulation we did not account for quasi-biennial oscillation (QBO) cooling and the cooling effects of volcanically induced ozone depletion. We estimated that both QBO and ozone depletion decrease the stratospheric temperature by about 2 K. The remaining 2 K stratospheric warming is in good agreement with observations. By comparing the runs with the Pinatubo aerosol forcing with those with no aerosols, we find that the model calculates a general cooling of the global troposphere, but with a clear winter warming pattern of surface air temperature over Northern Hemisphere continents. This pattern is consistent with the observed temperature patterns. The stratospheric heating and tropospheric summer cooling are directly caused by aerosol radiative effects, but the winter warming is indirect, produced by dynamical responses to the enhanced stratospheric latitudinal temperature gradient. The aerosol radiative forcing, stratospheric thermal response, and summer tropospheric cooling do not depend significantly on SST. The stratosphere-troposphere dynamic interactions and tropospheric climate response in winter are sensitive to SST

Communicating Mental Illness in the Black American Community

Human-human interactions are of central relevance for the success in professional and occupational environments, which also substantially influence quality of life. This is especially true in the case of individuals with high-functioning autism (HFA), who experience deficits in social cognition that often lead to social exclusion and unemployment. Despite good education and high motivation, individuals with HFA do not reach employment rates that are substantially higher than 50 %. This is an alarmingly high rate of unemployment considering that the United Nations have recently emphasized the inclusion of handicapped persons as a mandatory human right. To date, the specific needs of autistic persons with respect to their working environment are largely unexplored. It remains moreover an open question how support systems and activities, including newly developed communication devices for professional environments of individuals with HFA, should look like. The German health and social care systems are not adequately prepared for the proper support of this population. This leads us to suggest that supported employment programs should be developed for adults with HFA that specifically address their needs and requirements. Such programs should comprise (1) the adequate assessment of HFA, including a neuropsychological profile and an individual matching of persons' preferences with requirements of the working place, (2) on-the-job coaching activities that include systematic communication and interaction training, and (3) instruction of non-autistic peers, including colleagues and supervisors, about weaknesses and strengths of HFA

amsrpm: Robust Point Matching for Retention Time Aligment of LC/MS Data with R

Proteomics is the study of the abundance, function and dynamics of all proteins present in a living organism, and mass spectrometry (MS) has become its most important tool due to its unmatched sensitivity, resolution and potential for high-throughput experimentation. A frequently used variant of mass spectrometry is coupled with liquid chromatography (LC) and is denoted as "LC/MS". It produces two-dimensional raw data, where significant distortions along one of the dimensions can occur between different runs on the same instrument, and between instruments. A compensation of these distortions is required to allow for comparisons between and inference based on different experiments. This article introduces the amsrpm software package. It implements a variant of the Robust Point Matching (RPM) algorithm that is tailored for the alignment of LC and LC/MS experiments. Problem-specific enhancements include a specialized dissimilarity measure, and means to enforce smoothness and monotonicity of the estimated transformation function. The algorithm does not rely on pre-specified landmarks, it is insensitive towards outliers and capable of modeling nonlinear distortions. Its usefulness is demonstrated using both simulated and experimental data. The software is available as an open source package for the statistical programming language R.

Multiresistant Salmonella enterica serovar 4,[5],12:i:- in Europe: a new pandemic strain?

A marked increase in the prevalence of S. enterica serovar 4,[5],12:i:- with resistance to ampicillin, streptomycin, sulphonamides and tetracyclines (R-type ASSuT) has been noted in food-borne infections and in pigs/pig meat in several European countries in the last ten years. One hundred and sixteen strains of S. enterica serovar 4,[5],12:i:- from humans, pigs and pig meat isolated in England and Wales, France, Germany, Italy, Poland, Spain and the Netherlands were further subtyped by phage typing, pulsed-field gel electrophoresis and multilocus variable number tandem repeat analysis to investigate the genetic relationship among strains. PCR was performed to identify the fljB flagellar gene and the genes encoding resistance to ampicillin, streptomycin, sulphonamides and tetracyclines. Class 1 and 2 integrase genes were also sought. Results indicate that genetically related serovar 4,[5],12:i:- strains of definitive phage types DT193 and DT120 with ampicillin, streptomycin, sulphonamide and tetracycline resistance encoded by blaTEM, strA-strB, sul2 and tet(B) have emerged in several European countries, with pigs the likely reservoir of infection. Control measures are urgently needed to reduce spread of infection to humans via the food chain and thereby prevent the possible pandemic spread of serovar 4,[5],12:i:- of R-type ASSuT as occurred with S. Typhimurium DT104 during the 1990s

WMAP data and the curvature of space

Inter alia, the high precision WMAP data on Cosmic Microwave Background Radiation marginally indicate that the universe has positively curved (and hence spherical) spatial sections. In this paper, we take this data seriously and consider some of the consequences for the background dynamics. In particular, we show that this implies a limit to the number of e-foldings that could have taken place in the inflationary epoch; however this limit is consistent with some inflationary models that solve all the usual cosmological problems and are consistent with standard structure formation theory.Comment: 4 pages, 2 figure

Variation after Particle-Number Projection for the HFB Method with the Skyrme Energy Density Functional

Variation after particle-number restoration is incorporated for the first time into the Hartree-Fock-Bogoliubov framework employing the Skyrme energy density functional with zero-range pairing. The resulting projected HFB equations can be expressed in terms of the local gauge-angle-dependent densities. Results of projected calculations are compared with those obtained within the Lipkin-Nogami method in the standard version and with the Lipkin-Nogami method followed by exact particle-number projection.Comment: 11 pages, 6 figure

Foundation technology for developing an autonomous Complex Dwell-time Diagnostics (CDD) Tool

© 2015 ATRF, Commonwealth of Australia. All rights reserved. As the demand for rail services grows, intense pressure is placed on stations at the centre of rail networks where large crowds of rail passengers alight and board trains during peak periods. The time it takes for this to occur — the dwell-time — can become extended when high numbers of people congest and cross paths. Where a track section is operating at short headways, extended dwell-times can cause delays to scheduled services that can in turn cause a cascade of delays that eventually affect entire networks. Where networks are operating at close to their ceiling capacity, dwell-time management is essential and in most cases requires the introduction of special operating procedures. This paper details our work towards developing an autonomous Complex Dwell-time Diagnostics (CDD) Tool — a low cost technology, capable of providing information on multiple dwell events in real time. At present, rail operators are not able to access reliable and detailed enough data on train dwell operations and passenger behaviour. This is because much of the necessary data has to be collected manually. The lack of rich data means train crews and platform staff are not empowered to do all they could to potentially stabilise and reduce dwell-times. By better supporting service providers with high quality data analysis, the number of viable train paths can be increased, potentially delaying the need to invest in high cost hard infrastructures such as additional tracks. The foundation technology needed to create CDD discussed in this paper comprises a 3D image data based autonomous system capable of detecting dwell events during operations and then create business information that can be accessed by service providers in real time during rail operations. Initial tests of the technology have been carried out at Brisbane Central rail station. A discussion of the results to date is provided and their implications for next steps

Antimicrobial resistance characteristics and fitness of Gram-negative fecal bacteria from volunteers treated with minocycline or amoxicillin.

A yearlong study was performed to examine the effect of antibiotic administration on the bacterial gut flora. Gram-negative facultative anaerobic bacteria were recovered from the feces of healthy adult volunteers administered amoxicillin, minocycline or placebo, and changes determined in antimicrobial resistance (AMR) gene carriage. Seventy percent of the 1039 facultative anaerobic isolates recovered were identified by MALDI-TOF as Escherichia coli. A microarray used to determine virulence and resistance gene carriage demonstrated that AMR genes were widespread in all administration groups, with the most common resistance genes being bla TEM, dfr, strB, tet(A), and tet(B). Following amoxicillin administration, an increase in the proportion of amoxicillin resistant E. coli and a three-fold increase in the levels of bla TEM gene carriage was observed, an effect not observed in the other two treatment groups. Detection of virulence genes, including stx1A, indicated not all E. coli were innocuous commensals. Approximately 150 E. coli collected from 6 participants were selected for pulse field gel electrophoresis (PFGE), and a subset used for characterisation of plasmids and Phenotypic Microarrays (PM). PFGE indicated some E. coli clones had persisted in volunteers for up to 1 year, while others were transient. Although there were no unique characteristics associated with plasmids from persistent or transient isolates, PM assays showed transient isolates had greater adaptability to a range of antiseptic biocides and tetracycline; characteristics which were lost in some, but not all persistent isolates. This study indicates healthy individuals carry bacteria harboring resistance to a variety of antibiotics and biocides in their intestinal tract. Antibiotic administration can have a temporary effect of selecting bacteria, showing co-resistance to multiple antibiotics, some of which can persist within the gut for up to 1 year

Uncertainty Estimates for Theoretical Atomic and Molecular Data

Sources of uncertainty are reviewed for calculated atomic and molecular data that are important for plasma modeling: atomic and molecular structure and cross sections for electron-atom, electron-molecule, and heavy particle collisions. We concentrate on model uncertainties due to approximations to the fundamental many-body quantum mechanical equations and we aim to provide guidelines to estimate uncertainties as a routine part of computations of data for structure and scattering.Comment: 65 pages, 18 Figures, 3 Tables. J. Phys. D: Appl. Phys. Final accepted versio