A special family of stacked central configurations: Lagrange plus Euler in one

This is a post-peer-review, pre-copyedit version of an article published in Journal of dynamics and differential equations. The final authenticated version is available online at: http://dx.doi.org/10.1007/s10884-018-9647-1We show the existence of a family of stacked central configurations in the planar five-body problem with a special property. Three bodies m1, m2 and m3, ordered from left to right, are collinear and form an Euler central configuration, and the other two bodies m4 and m5, together with m2 are at the vertices of an equilateral triangle and form a Lagrange central configuration.Peer ReviewedPostprint (author's final draft

Low-intensity acoustic waves detection using an interferometer

We present a device built in fiber optic capable of detecting acoustic signals in water, using a buzzer as the vibration source, this buzzer operates at a frequency range from 3 kHz to 30 kHz. This device operates under the principle of a Sagnac interferometer, where the acoustic waves emitted by the buzzer are detected as a phase modulation in the monitored signal. The measured phase is due to strain experienced by the fiber optic which is caused by the vibrations emitted by the buzzer. The device can detect signals up to 7 cm away from the acoustic source

A family of stacked central configurations in the planar five-body problem

We study planar central configurations of the five-body problem where three bodies, m1,m2 and m3, are collinear and ordered from left to right, while the other two, m4 and m5, are placed symmetrically with respect to the line containing the three collinear bodies. We prove that when the collinear bodies form an Euler central configuration of the three-body problem with m1=m3, there exists a new family, missed by Gidea and Llibre (Celest Mech Dyn Astron 106:89-107, 2010), of stacked five-body central configuration where the segments m4m5 and m1m3 do not intersect

Central configurations in the five-body problem : Rhombus plus one

We show the existence of central configurations in the planar five-body problem where four bodies are located at the vertices of a rhombus, called rhombus plus one central configurations. Concretely we prove analytically their existence when one diagonal is nearly equal to the sides of the rhombus and when the two diagonals are either equal or nearly equal. In addition, we prove that given a rhombus plus one configuration, the corresponding vector of positive masses that makes the configuration central, if exists, is unique

Use of liraglutide in the patient with obesity and type 2 diabetes mellitus: a literature review

Obesity and type 2 diabetes mellitus represent two of the most pressing public health challenges globally. In recent decades, an alarming increase in the prevalence of both conditions has been observed, which has led to a significant increase in the burden of disease and an increased search for effective therapeutic strategies. As evidence accumulates on the efficacy and safety of Liraglutide in this patient population, a comprehensive review of the available scientific literature is necessary. The objective of this literature review is to analyze and synthesize relevant studies investigating the use of liraglutide in patients with obesity and type 2 diabetes mellitus, in order to provide a comprehensive view on its effectiveness, indications, complications and management. In conclusion, the use of liraglutide in patients with obesity and type 2 diabetes mellitus has been shown to be an effective therapeutic option to improve glycemic control, promote weight loss and reduce cardiovascular risk. This drug, as a GLP-1 receptor agonist, stimulates insulin secretion, suppresses excessive glucagon release and delays gastric emptying, which contributes to the improvement in glycemic control

Calidad de la Tithonia diversifolia en una zona del Valle del Cauto

13 páginas, 5 tablas.This experiment was carried out with the objective of determining the nutritive value of Tithonia diversifolia to different bud ages during the two periods of the year. A 0.5 ha field was used, where a standardization cut at 15 cm high from the soil was applied at the beginning of each period. The ages taken into consideration were 60, 120 and 180 days, and the elements evaluated were the RP, the fibrous fractioning, the dry matter In vitro digestibility, the wall cell digestibility and the tanins. To this purpose, a random- block design with three treatments and four repetitions was used through the application of a double classification analysis, and the average results were compared by means of the multiple ranges Duncan test. The statistical program utilized was Statiics version 6.0 for Windows. In the chapter that deals with the analysis of the results, it is evident that the dry matter, NDF, ADF, ADL, Hemicellulous, TF, TCT, CTAF and FTC increased their content (29. 47 %, 50. 51 %, 32. 12 %, 32. 12 %, 18. 39 %, 6.47, 13. 11, 10. 12, and 2. 99 g/kg respectively) at the age of 180 days, whereas the raw protein, the cellulous, the cell content, the In vitro digestibility and the wall cell digestibility decreased with their highest value (28.95, 21.08, 56.34, 78.59 y 76.61 %) at the age of 60 days. As a conclusion, age had a marked effect on the behavior of the evaluated elements, which was stronger during the rainy season, decreasing the nutritive quality.Trabajo realizado con financiación del Programa de Cooperación Interuniversitaria e Investigación Científica de la Agencia Española de Cooperación Internacional para el Desarrollo (Proyecto AECID A/023167/09).Peer Reviewe

Dribble Deficit enables measurement of dribbling speed independent of sprinting speed in collegiate, male, basketball players

Ramirez-Campillo, R, Gentil, P, Moran, J, Dalbo, VJ, and Scanlan, AT. Dribble Deficit enables measurement of dribbling speed independent of sprinting speed in collegiate, male, basketball players. J Strength Cond Res XX(X): 000-000, 2019-The aim of this study was to determine the relationships between sprinting and dribbling speed in basketball during linear and change-of-direction (COD) sprints using total dribbling time and Dribble Deficit. Collegiate, male, basketball players (n = 10; 21.0 ± 1.6 years) performed linear and COD sprints with and without dribbling a ball. Linear dribbling sprints were measured for the dominant and nondominant hands, whereas COD dribbling sprints involved bilateral use of hands. Dribble Deficit was determined as the difference between total time (second) during each dribbling trial and the equivalent nondribbling trial for linear and COD sprints. Simple linear regression analyses were performed during linear and COD sprints to determine the relationship (R) and shared variance (R) between (a) sprinting times and total dribbling times and (b) sprinting times and Dribble Deficit. Large to very large, significant relationships were evident between linear sprinting and dribbling time for dominant (R = 0.86; R = 0.74, p = 0.001) and nondominant hands (R = 0.80; R = 0.65, p = 0.005). Trivial relationships were apparent between linear sprinting time and Dribble Deficit with dominant (R = 0.10; R = 0.01, p = 0.778) and nondominant hands (R = 0.03; R = 0.00, p = 0.940). A very large relationship was evident between COD sprinting and dribbling time (R = 0.91; R = 0.82, p < 0.001), whereas a trivial relationship was observed between COD sprinting time and COD Dribble Deficit (R = -0.23; R = 0.05, p = 0.530). Dribble Deficit eliminates the strong influence of sprinting speed on outcome measures typically seen when using tests predicated on total dribbling time. Consequently, Dribble Deficit may be of added use in basketball test batteries to measure dribbling speed across linear and multidirectional movement paths

Effects of the breed, sex and age on cellular content and growth factor release from equine pure-platelet rich plasma and pure-platelet rich gel

Background: There is no information on the effects of the breed, gender and age on the cellular content and growth factor (GF) release from equine pure-platelet rich plasma (P-PRP) and pure-platelet rich gel (P-PRG). The objectives of this study were: 1) to compare the cellular composition of P-PRP with whole blood and platelet poor plasma (PPP); 2) to compare the concentration of transforming GF beta 1 (TGF-β1) and platelet derived GF isoform BB (PDGF-BB) between P-PRP treated with non-ionic detergent (P-PRP+NID), P-PRG (activated with calcium gluconate -CG-), PPP+NID, PPP gel (PPG), and plasma and; 3) to evaluate and to correlate the effect of the breed, gender and age on the cellular and GF concentration for each blood component. Forty adult horses, 20 Argentinean Creole Horses (ACH) and, 20 Colombian Creole Horses (CCH) were included. Data were analyzed by parametric (i.e.: t-test, one way ANOVA) and non parametric (Kruskal-Wallis test, Wilcoxon test) tests. Correlation analysis was also performed by using the Spearman and Pearson tests. A p ≤ 0.05 was set as significant for all tests. All the blood components were compared for platelet (PLT), leukocyte (WBC), TGF-β1 and PDGF-BB concentrations. The effect of the breed, gender and age on these variables was analyzed. A P ≤ 0.05 was accepted as significant for all the tests. Results: PLT counts were 1.8 and 0.6 times higher in P-PRP than in whole blood and PPP, respectively; WBC counts were 0.5 and 0.1 times lower in P-PRP, in comparison with whole blood and PPP, respectively. TGF-β1 and PDGF-BB concentrations were 2.3 and 262 times higher, respectively, in P-PRG than in plasma, and 0.59 and 0.48 times higher, respectively, in P-PRG than in PPG. P-PRG derived from CCH females or young horses presented significantly (P < 0.001) higher PDGF-BB concentrations than P-PRG derived from ACH males or older horses. Conclusions: Our results indicated that P-PRP obtained by a manual method was affected by intrinsic factors such as the breed, gender and age. Equine practitioners should be aware that cellular and GF release from P-PRP/P-PRG could change according with the intrinsic variables associated with a patient in particular

Evaluation of learning outcomes of humanities curricula in medical students. A meta-review of narrative and systematic reviews

Objectives: To assess the expected learning outcomes of medical humanities subjects in medical studies curricula. To connect those expected learning outcomes with the types of knowledge to be acquired in medical education. Methods: Meta-review of systematic and narrative reviews. Cochrane Library, MEDLINE (Pubmed), Embase, CINAHL, and ERIC were searched. In addition, references from all the included studies were revised, and the ISI Web of Science and DARE were searched. Results: A total of 364 articles were identified, of which six were finally included in the review. Learning outcomes describe the acquisition of knowledge and skills to improve the relationship with patients, as well as the incorporation of tools to reduce burnout and promote professionalism. Programs that focus on teaching humanities promote diagnostic observation skills, the ability to cope with uncertainty in clinical practice, and the development of empathetic behaviors. Conclusion: The results of this review show heterogeneity in the teaching of medical humanities, both in terms of content and at the formal level. Humanities learning outcomes are part of the necessary knowledge for good clinical practice. Consequently, the epistemological approach provides a valid argument for including the humanities in medical curricula