The prevalence of insomnia in the general population in China: A meta-analysis

This is the first meta-analysis of the pooled prevalence of insomnia in the general population of China. A systematic literature search was conducted via the following databases: PubMed, PsycINFO, EMBASE and Chinese databases (China National Knowledge Interne (CNKI), WanFang Data and SinoMed). Statistical analyses were performed using the Comprehensive Meta-Analysis program. A total of 17 studies with 115,988 participants met the inclusion criteria for the analysis. The pooled prevalence of insomnia in China was 15.0% (95% Confidence interval [CI]: 12.1%-18.5%). No significant difference was found in the prevalence between genders or across time period. The pooled prevalence of insomnia in population with a mean age of 43.7 years and older (11.6%; 95% CI: 7.5%-17.6%) was significantly lower than in those with a mean age younger than 43.7 years (20.4%; 95% CI: 14.2%-28.2%). The prevalence of insomnia was significantly affected by the type of assessment tools (Q = 14.1, P = 0.001). The general population prevalence of insomnia in China is lower than those reported in Western countries but similar to those in Asian countries. Younger Chinese adults appear to suffer from more insomnia than older adults

Background heavy metal concentrations (Cd, Cu, Ni, Pb, Fe and Zn) in modiolus sp. collected from the coast waters of Peninsular Malaysia: A preliminary study.

The heavy metal concentrations in little black mussel Modiolus sp. have not been previously reported from Malaysia. In this study, the mussel species is widely distributed the coastal waters of Peninsular Malaysia and this mussel are found in Pantai Sri Tujuh [Kelantan], K. Kedah [Kedah], Kg. Sg. Berembang, Kg. Sg. Baru and Kuala Perlis [Perlis], and Bagan Tiang [Perak], Jeram and Sg. Janggut [Selangor]. From the 12 mussel populations collected in this study, the ranges of the metal concentrations (μg/g dry weight) in the total soft tissues and shells were 2.246.73 and 4.159.53 for Cd, 10.0231.94 and 6.2810.17 for Cu, 1.3549.38 and 22.2248.45 for Ni, 4.7556.27, and 54.86112.31 for Pb, 5985582 and 158 544 for Fe, and 43.8162 and 1.5025.4 for Zn. To our knowledge, this is the first report on the metal concentrations of Modiolus sp. collected from the coastal waters of Peninsular Malaysia. The present data are important for future ecotoxicological, genetic biochemical and molecular studies in establishing this marine mussel as a good biomonitor

Depuration of trace metals in transplanted perna viridis from polluted site at Kg Pasir Puteh to relatively unpolluted sites at Kg Sg Melayu and Sg Belungkor in the straits of Johore

In this study, the green-lipped mussels Perna viridis were transplanted from a relatively unpolluted site at Kg. Sg Melayu (KSM) to a known polluted site at Kg Pasir Puteh (KPP) and an unpolluted site at Sg. Belungkor (SB). Total soft tissues of mussels were determined for Ag, As, Be, Co, Cr, Cs, Hg, Li, Mn, Se, Sr and V by using an Inductively Coupled Plasma-mass Spectrometer. After transplantation periods (2 and 6 weeks) to KPP, concentrations of As, Co, Cr, Hg, Li, Be, V, Cs, Mn and Sr increased but the concentrations of Ag and Se decreased after transplantation of 2 and 6 weeks. This indicated that KPP is almost confirmed as having the highest bioavailabilities of the above 10 metals than KSM and SB. However, the higher levels of Ag and Se found in the transplanted mussels at KSM should be investigated in future studies. After transplantation periods (2 and 6 weeks) to SB, concentrations of Co, Cr, Hg, Be, V, Cs, Se, Mn and Sr decreased but the concentrations of Ag and Li increased after transplantation of 2 and 6 weeks. This verified that SB is suitable coastal water for depuration of Co, Cr, Hg, Be, V, Cs, Se, Mn and Sr. However, higher levels of Ag and Li at SB than KSM could be attributed to unknown pollution source in the surrounding area which should merit further studies

Assessment of heavy metal pollution in the Straits of Johore by using transplanted caged mussels, Perna viridis

In this study, a polluted site at Kg. Pasir Puteh was assessed for heavy metal pollution by using transplanted caged mussel (Perna viridis) from a relatively clean population, Sg. Melayu; both are located in the Strait of Johore. For control purposes, the P. viridis from Kg. Pasir Puteh were also simultaneously transplanted in Sg. Melayu at the same time. It was found that Zn was the metal which got accumulated fastest in the transplanted mussel while Cd was the slowest. This study indicated that the byssus of Perna viridis was most effective for biomonitoring of Cd, Ni, Pb and Zn, while the shell could be used for the biomonitoring of Cu, Ni and Pb and the total soft tissue for the biomonitoring of Ni since they were able to accumulate and eliminate the respective metals well. By using mussel as a biomonitor, the present study found that Kg. Pasir Puteh, which is located in the eastern part of the Strait of Johore, had significantly higher contamination and bioavailabilities of Cd, Cu, Fe, Ni, Pb and Zn. Therefore, the use of the transplanted caged mussels is very useful for heavy metal assessment purposes since it can increase the validity of data interpretation by minimizing ecological factors

Success Factors of Small and Medium-Sized International Enterprises in the Chinese Market from the Perspective of Polish Direct Investment (Cultural Approach)

Globalization has resulted in increasing transfer of firms operations, regardless of their size, to other countries. The recent dynamic emergence of China in the global economy, connecting with the vast inflows of foreign direct investment in their territory and common adjustments problems of many Western companies, has resulted in growing interest for best suitable business practices to this culturally and socially different environment. In this article, the key factors critical to the success of international companies in this region are introduced, with particular consideration to indigenous cultural elements and specific operation requirements of small and medium-sized enterprises in Business-to-Business sectors. The presented information are based on the broad literature review, five years of direct observation and thirty eight interviews conducted with Polish managers directly residing in China. In addition, some practical recommendations for managers and further research are given.Globalizacja wymusza na firmach, niezależnie od ich wielkości, coraz częstsze przenoszenie operacji do innych krajów. Dynamiczne pojawienie się Chin w światowej gospodarce i szeroki napł;yw zagranicznych inwestycji bezpośrednich na ich teren oraz problemy adaptacyjne wielu zachodnich przedsiębiorstw, spowodował;y zainteresowanie najlepszymi praktykami biznesowymi dostosowanymi do tego odmiennego kulturowo i społ;ecznie otocznia. W artykule zaprezentowane został;y najważniejsze czynnik mające wpł;yw na osiągnięcie sukcesu przez firmy międzynarodowe na tym obszarze, ze szczególnym uwzględnieniem aspektów kulturowych i specyfiki dział;ania mał;ych i średnich podmiotów na rynkach B2B. Prezentowane informacje są oparte na przeglądzie literatury, pięcioletnich obserwacjach bezpośrednich oraz trzydziestu ośmiu wywiadach przeprowadzonych z menadżerami polskich przedsiębiorstw odpowiedzialnymi za operacje w Chinach. Dodatkowo wskazano kilka praktycznych rekomendacji menadżerskich oraz możliwości dalszych badań

DNA hybridization to mismatched templates: a chip study

High-density oligonucleotide arrays are among the most rapidly expanding technologies in biology today. In the {\sl GeneChip} system, the reconstruction of the target concentration depends upon the differential signal generated from hybridizing the target RNA to two nearly identical templates: a perfect match (PM) and a single mismatch (MM) probe. It has been observed that a large fraction of MM probes repeatably bind targets better than the PMs, against the usual expectation from sequence-specific hybridization; this is difficult to interpret in terms of the underlying physics. We examine this problem via a statistical analysis of a large set of microarray experiments. We classify the probes according to their signal to noise ($S/N$) ratio, defined as the eccentricity of a (PM, MM) pair's `trajectory' across many experiments. Of those probes having large $S/N$ ($>3$) only a fraction behave consistently with the commonly assumed hybridization model. Our results imply that the physics of DNA hybridization in microarrays is more complex than expected, and they suggest new ways of constructing estimators for the target RNA concentration.Comment: 3 figures 1 tabl

Leptogenesis from Soft Supersymmetry Breaking (Soft Leptogenesis)

Soft leptogenesis is a scenario in which the cosmic baryon asymmetry is produced from a lepton asymmetry generated in the decays of heavy sneutrinos (the partners of the singlet neutrinos of the seesaw) and where the relevant sources of CP violation are the complex phases of soft supersymmetry-breaking terms. We explain the motivations for soft leptogenesis, and review its basic ingredients: the different CP-violating contributions, the crucial role played by thermal corrections, and the enhancement of the efficiency from lepton flavour effects. We also discuss the high temperature regime $T > 10^7$ GeV in which the cosmic baryon asymmetry originates from an initial asymmetry of an anomalous $R$-charge, and soft leptogenesis reembodies in $R$-genesis.Comment: References updated. Some minor corrections to match the published versio

Flavoured soft leptogenesis and natural values of the B term

We revisit flavour effects in soft leptogenesis relaxing the assumption of universality for the soft supersymmetry breaking terms. We find that with respect to the case in which the heavy sneutrinos decay with equal rates and equal CP asymmetries for all lepton flavours, hierarchical flavour configurations can enhance the efficiency by more than two orders of magnitude. This translates in more than three order of magnitude with respect to the one-flavour approximation. We verify that lepton flavour equilibration effects related to off-diagonal soft slepton masses are ineffective for damping these large enhancements. We show that soft leptogenesis can be successful for unusual values of the relevant parameters, allowing for $B\sim {\cal O}({\rm TeV})$ and for values of the washout parameter up to $m_{\rm eff}/m_* \sim 5\times 10^{3}$.Comment: 23 pages, 5 figures postscript, Minor changes to match the published version in JHE

Wireless body sensor design for intra-vaginal temperature monitoring

Sensor nodes are small devices able to collect and retrieve sensorial data. The use of these sensors for medical purposes offers valuable contributions to improve patients’ healthcare, both for diagnosis and therapeutics monitoring. An important and common parameter used on healthcare diagnosis is the body temperature. It is monitored on several matters related with gynecological and obstetrics issues but, usually it is measure at the skin surface. Then, this paper proposes the design concepts of a new intra-body sensor for long-term intra-vaginal temperature collection. The embedded IEEE 802.15.4 communication module allows the integration of this sensor in wireless sensor networks for remote data access and monitoring. It is presented the sensor architecture, the construction of the corresponding testbed, and its performance evaluation. This sensor may be used on several applications, including fertile and ovulation period detection, and preterm labor prevention

Nonequilibrium relaxation of the two-dimensional Ising model: Series-expansion and Monte Carlo studies

We study the critical relaxation of the two-dimensional Ising model from a fully ordered configuration by series expansion in time t and by Monte Carlo simulation. Both the magnetization (m) and energy series are obtained up to 12-th order. An accurate estimate from series analysis for the dynamical critical exponent z is difficult but compatible with 2.2. We also use Monte Carlo simulation to determine an effective exponent, z_eff(t) = - {1/8} d ln t /d ln m, directly from a ratio of three-spin correlation to m. Extrapolation to t = infinity leads to an estimate z = 2.169 +/- 0.003.Comment: 9 pages including 2 figure