261 research outputs found
TERRA/MOPITT Measurements of Tropospheric Carbon Monoxide Distributions in Support of INTEX
Interaction with the ongoing satellite measurements programs was an important goal of INTEX- A. The Terra/MOPITT instrument had been making global measurements of the tropospheric carbon monoxide (CO) distribution for 4 years, and was in a unique position to provide valuable support during the field campaign. Remote sensing of CO directly addressed the scientific questions motivating the IXTEX-A strategy and deployment, and measurement of this gas was rated as being mission critical. CO is an important trace gas in tropospheric chemistry due to its role in determining the atmospheric oxidizing capacity, as an ozone precursor, and as an indicator and tracer of both natural and anthropogenic pollution arising from incomplete combustion. The satellite perspective provided the more general temporal and spatial context to the aircraft and ground-based measurements during the subsequent scientific analysis. We proposed to build on the experience of supplying MOPITT data to previous field campaigns, such as TRACE-P. We provided expedited MOPITT data processing in near real-time, along with basic analysis of the measurements to indicate, where possible, the origin of the CO plumes that impacted the regions of flight operations and other in situ measurement activities. To ensure maximum exploitation of the satellite information, we will also had a scientist in the field to present and interpret the MOPITT data for the INTEX team, and to help ensure its utility in flight planning
Measurement of the proton electric to magnetic form factor ratio from \vec ^1H(\vec e, e'p)
We report the first precision measurement of the proton electric to magnetic
form factor ratio from spin-dependent elastic scattering of longitudinally
polarized electrons from a polarized hydrogen internal gas target. The
measurement was performed at the MIT-Bates South Hall Ring over a range of
four-momentum transfer squared from 0.15 to 0.65 (GeV/c).
Significantly improved results on the proton electric and magnetic form factors
are obtained in combination with previous cross-section data on elastic
electron-proton scattering in the same region.Comment: 4 pages, 2 figures, submitted to PR
The Charge Form Factor of the Neutron at Low Momentum Transfer from the Reaction
We report new measurements of the neutron charge form factor at low momentum
transfer using quasielastic electrodisintegration of the deuteron.
Longitudinally polarized electrons at an energy of 850 MeV were scattered from
an isotopically pure, highly polarized deuterium gas target. The scattered
electrons and coincident neutrons were measured by the Bates Large Acceptance
Spectrometer Toroid (BLAST) detector. The neutron form factor ratio
was extracted from the beam-target vector asymmetry
at four-momentum transfers , 0.20, 0.29 and 0.42
(GeV/c).Comment: 5 pages, 3 figures, submitted to Phys. Rev. Let
Longitudinal-Transverse Separations of Structure Functions at Low for Hydrogen and Deuterium
We report on a study of the longitudinal to transverse cross section ratio,
, at low values of and , as determined from
inclusive inelastic electron-hydrogen and electron-deuterium scattering data
from Jefferson Lab Hall C spanning the four-momentum transfer range 0.06 GeV. Even at the lowest values of , remains
nearly constant and does not disappear with decreasing , as expected. We
find a nearly identical behaviour for hydrogen and deuterium.Comment: 4 pages, 2 gigure
Reduced LIMK2 expression in colorectal cancer reflects its role in limiting stem cell proliferation
Objective: Colorectal cancer (CRC) is a major contributor to cancer mortality and morbidity. LIM kinase 2 (LIMK2) promotes tumour cell invasion and metastasis. The objectives of this study were to determine how LIMK2 expression is associated with CRC progression and patient outcome, and to use genetically modified Drosophila and mice to determine how LIMK2 deletion affects gastrointestinal stem cell regulation and tumour development.<p></p>
Design: LIMK2 expression and activity were measured by immunostaining tumours from CRC-prone mice, human CRC cell lines and 650 human tumours. LIMK knockdown in Drosophila or Limk2 deletion in mice allowed for assessment of their contributions to gastrointestinal stem cell homeostasis and tumour development.<p></p>
Results: LIMK2 expression was reduced in intestinal tumours of cancer-prone mice, as well as in human CRC cell lines and tumours. Reduced LIMK2 expression and substrate phosphorylation were associated with shorter patient survival. Genetic analysis in Drosophila midgut and intestinal epithelial cells isolated from genetically modified mice revealed a conserved role for LIMK2 in constraining gastrointestinal stem cell proliferation. Limk2 deletion increased colon tumour size in a colitis-associated colorectal mouse cancer model.<p></p>
Conclusions: This study revealed that LIMK2 expression and activity progressively decrease with advancing stage, and supports the hypothesis that there is selective pressure for reduced LIMK2 expression in CRC to relieve negative constraints imposed upon gastrointestinal stem cells.<p></p>
Velocity Dispersion of Excited H2
We present a study of the high rotational bands (J > 2) of H2 toward 4 early
type galactic stars: HD 73882, HD 192639, HD 206267, and HD 207538. In each
case, the velocity dispersion - characterized by the spectrum fitting parameter
b - increases with the level of excitation, a phenomenon that has previously
been detected by the Copernicus and IMAPS observatories. In particular, we show
with 4 sigma confidence that for HD 192639 it is not possible to fit all J
levels with a single b value, and that higher b values are needed for the
higher levels. The amplitude of the line broadening, which can be as high as 10
km s^-1, makes explanations such as inhomogeneous spatial distribution
unlikely. We investigate a mechanism in which the broadening is due to the
molecules that are rotationally excited through the excess energy acquired
after their formation on a grain (H2-formation pumping). We show that different
dispersions would be a natural consequence of this mechanism. We note however
that such process would require a formation rate 10 times higher then what was
inferred from other observations. In view of the difficulty to account for the
velocity dispersion as thermal broadening (T would be around 10,000 K), we
conclude then that we are most certainly observing some highly turbulent warm
layer associated with the cold diffuse cloud. Embedded in a magnetic field, it
could be responsible for the high quantities of CH+ measured in the cold
neutral medium.Comment: accepted in Ap
Measurements of electron-proton elastic cross sections for
We report on precision measurements of the elastic cross section for
electron-proton scattering performed in Hall C at Jefferson Lab. The
measurements were made at 28 unique kinematic settings covering a range in
momentum transfer of 0.4 5.5 . These measurements
represent a significant contribution to the world's cross section data set in
the range where a large discrepancy currently exists between the ratio of
electric to magnetic proton form factors extracted from previous cross section
measurements and that recently measured via polarization transfer in Hall A at
Jefferson Lab.Comment: 17 pages, 18 figures; text added, some figures replace
Nuclear transparency from quasielastic A(e,e'p) reactions uo to Q^2=8.1 (GeV/c)^2
The quasielastic (e,ep) reaction was studied on targets of
deuterium, carbon, and iron up to a value of momentum transfer of 8.1
(GeV/c). A nuclear transparency was determined by comparing the data to
calculations in the Plane-Wave Impulse Approximation. The dependence of the
nuclear transparency on and the mass number was investigated in a
search for the onset of the Color Transparency phenomenon. We find no evidence
for the onset of Color Transparency within our range of . A fit to the
world's nuclear transparency data reflects the energy dependence of the free
proton-nucleon cross section.Comment: 11 pages, 6 figure
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