Static interactions and stability of matter in Rindler space

Dynamical issues associated with quantum fields in Rindler space are addressed in a study of the interaction between two sources at rest generated by the exchange of scalar particles, photons and gravitons. These static interaction energies in Rindler space are shown to be scale invariant, complex quantities. The imaginary part will be seen to have its quantum mechanical origin in the presence of an infinity of zero modes in uniformly accelerated frames which in turn are related to the radiation observed in inertial frames. The impact of a uniform acceleration on the stability of matter and the properties of particles is discussed and estimates are presented of the instability of hydrogen atoms when approaching the horizon.Comment: 28 pages, 4 figure

Possible ΔΔ\Delta\Delta dibaryons in the quark cluster model

In the framework of RGM, the binding energy of one channel $\Delta\Delta_{(3,0)}$($d^*$) and $\Delta\Delta_{(0,3)}$ are studied in the chiral SU(3) quark cluster model. It is shown that the binding energies of the systems are a few tens of MeV. The behavior of the chiral field is also investigated by comparing the results with those in the SU(2) and the extended SU(2) chiral quark models. It is found that the symmetry property of the $\Delta\Delta$ system makes the contribution of the relative kinetic energy operator between two clusters attractive. This is very beneficial for forming the bound dibaryon. Meanwhile the chiral-quark field coupling also plays a very important role on binding. The S-wave phase shifts and the corresponding scattering lengths of the systems are also given.Comment: LeTex with 2 ps figure

Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model.

Pancreatic cancer is a highly lethal disease in part due to incomplete tumor resection. Targeting by tumor-specific antibodies conjugated with a fluorescent label can result in selective labeling of cancer in vivo for surgical navigation. In the present study, we describe a patient-derived orthotopic xenograft model of pancreatic cancer that recapitulated the disease on a gross and microscopic level, along with physiologic clinical manifestations. We additionally show that the use of an anti-CEA antibody conjugated to the near-infrared (NIR) fluorescent dye, IRDye800CW, can selectively highlight the pancreatic cancer and its metastases in this model with a tumor-to-background ratio of 3.5 (SEM 0.9). The present results demonstrate the clinical potential of this labeling technique for fluorescence-guided surgery of pancreatic cancer

Diurnal metabolic regulation of isoflavones and soyasaponins in soybean roots

Isoflavones and soyasaponins are major specialized metabolites accumulated in soybean roots and secreted into the rhizosphere. Unlike the biosynthetic pathway, the transporters involved in metabolite secretion remain unknown. The developmental regulation of isoflavone and soyasaponin secretions has been recently reported, but the diurnal regulation of their biosynthesis and secretion still needs to be further studied. To address these challenges, we conducted transcriptome and metabolite analysis using hydroponically grown soybean plants at 6-hr intervals for 48 hr in a 12-hr-light/12-hr-dark condition. Isoflavone and soyasaponin biosynthetic genes showed opposite patterns in the root tissues; that is, the former genes are highly expressed in the daytime, while the latter ones are strongly induced at nighttime. GmMYB176 encoding a transcription factor of isoflavone biosynthesis was upregulated from ZT0 (6:00 a.m.) to ZT6 (12:00 a.m.), followed by the induction of isoflavone biosynthetic genes at ZT6. The isoflavone aglycone content in the roots accordingly increased from ZT6 to ZT18 (0:00 a.m.). The isoflavone aglycone content in root exudates was kept consistent throughout the day, whereas that of glucosides increased at ZT6, which reflected the decreased expression of the gene encoding beta-glucosidase involved in the hydrolysis of apoplast-localized isoflavone conjugates. Co-expression analysis revealed that those isoflavone and soyasaponin biosynthetic genes formed separate clusters, which exhibited a correlation to ABC and MATE transporter genes. In summary, the results in this study indicated the diurnal regulation of isoflavone biosynthesis in soybean roots and the putative transporter genes responsible for isoflavone and soyasaponin transport

Long- and medium-range components of the nuclear force in quark-model based calculations

Quark-model descriptions of the nucleon-nucleon interaction contain two main ingredients, a quark-exchange mechanism for the short-range repulsion and meson-exchanges for the medium- and long-range parts of the interaction. We point out the special role played by higher partial waves, and in particular the 1F3, as a very sensitive probe for the meson-exchange part employed in these interaction models. In particular, we show that the presently available models fail to provide a reasonable description of higher partial waves and indicate the reasons for this shortcoming.Comment: 19 pages, 7 figure

The Two-Nucleon Potential from Chiral Lagrangians

Chiral symmetry is consistently implemented in the two-nucleon problem at low-energy through the general effective chiral lagrangian. The potential is obtained up to a certain order in chiral perturbation theory both in momentum and coordinate space. Results of a fit to scattering phase shifts and bound state data are presented, where satisfactory agreement is found for laboratory energies up to about 100 Mev.Comment: Postscript file; figures available by reques

Geographical location affects the levels and association of trimethylamine N-oxide with heart failure mortality in BIOSTAT-CHF:a post-hoc analysis

No abstract available