Awareness of lifestyle and colorectal cancer risk:findings from the BeWEL study

It is estimated that 47% of colorectal cancers (CRC) could be prevented by appropriate lifestyles. This study aimed to identify awareness of the causes of CRC in patients who had been diagnosed with a colorectal adenoma through the Scottish Bowel Screening Programme and subsequently enrolled in an intervention trial (using diet and physical activity education and behavioural change techniques) (BeWEL). At baseline and 12-month follow-up, participants answered an open-ended question on factors influencing CRC development. Of the 329 participants at baseline, 40 (12%) reported that they did not know any risk factors and 36 (11%) failed to identify specific factors related to diet and activity. From a potential knowledge score of 1 to 6, the mean score was 1.5 (SD 1.1, range 0 to 5) with no difference between intervention and control groups. At follow-up, the intervention group had a significantly greater knowledge score and better weight loss, diet, and physical activity measures than the control group. Awareness of relevant lifestyle factors for CRC remains low in people at increased risk of the disease. Opportunities within routine NHS screening to aid the capability (including knowledge of risk factors) of individuals to make behavioural changes to reduce CRC risk deserve exploration.Additional co-author: The BeWEL team. The BeWEL Team consists of Shaun Treweek, Fergus Daly, Jill Belch, Jackie Rodger, Alison Kirk, Anne Ludbrook, Petra Rauchhaus, Patricia Norwood, Joyce Thompson, and Jane Wardle

Meeting the challenges of recruitment to multicentre, community-based, lifestyle-change trials : a case study of the BeWEL trial

Peer reviewedPublisher PD

Bipartite Anterior Extraperitoneal Teratoma: Evidence for the Embryological Origins of Teratomas?

Teratomas are thought to arise from totipotent primordial germ cells (PGCs) Dehner (1983) which may miss their target destination Moore and Persaud (1984). Teratomas can occur anywhere from the brain to the coccygeal area but are usually in the midline close to the embryological position of the gonadal ridges Bale (1984), Nguyen and Laberge (2000). We report a case of a bipartite anterior extraperitoneal teratoma. This is an unusual position for a teratoma, but one which may support the “missed target” theory of embryology

Formalism for dilepton production via virtual photon bremsstrahlung in hadronic reactions

We derive a set of new formulas for various distributions in dilepton production via virtual photon bremsstrahlung from pseudoscalar mesons and unpolarized spin-one-half fermions. These formulas correspond to the leading and sub-leading terms in the Low-Burnett-Kroll expansion for real photon bremsstrahlung. The relation of our leading-term formulas to previous works is also shown. Existing formulas are examined in the light of Lorentz covariance and gauge invariance. Numerical comparison is made in a simple example, where an "exact" formula and real photon data exist. The results reveal large discrepancies among different bremsstrahlung formulas. Of all the leading-term bremsstrahlung formulas, the one derived in this work agrees best with the exact formula. The issues of M_T-scaling and event generators are also addressed.Comment: 37 pages, RevTeX, epsf.sty, 10 embedded figure

Vector meson couplings to vector and tensor currents in extended NJL quark model

A simple explanation of the dynamic properties of vector mesons is given in the framework of extended Nambu - Jona-Lasinio quark model. New mass relations among the hadron vector resonances are derived. The results of this approach are in good accordance with the QCD sum rules, the lattice calculations and the experimental data.Comment: 4 pages, 2 figure

Hadron Correlators and the Structure of the Quark Propagator

The structure of the quark propagator of $QCD$ in a confining background is not known. We make an Ansatz for it, as hinted by a particular mechanism for confinement, and analyze its implications in the meson and baryon correlators. We connect the various terms in the K\"allen-Lehmann representation of the quark propagator with appropriate combinations of hadron correlators, which may ultimately be calculated in lattice $QCD$. Furthermore, using the positivity of the path integral measure for vector like theories, we reanalyze some mass inequalities in our formalism. A curiosity of the analysis is that, the exotic components of the propagator (axial and tensor), produce terms in the hadron correlators which, if not vanishing in the gauge field integration, lead to violations of fundamental symmetries. The non observation of these violations implies restrictions in the space-time structure of the contributing gauge field configurations. In this way, lattice $QCD$ can help us analyze the microscopic structure of the mechanisms for confinement.Comment: 12 pp in LaTeX, preprint Univ. of Valencia, FTUV/94-16, IFIC/94-15. To appear in Z.Phys.

Weak gauge principle and electric charge quantization

Starting from a weak gauge principle we give a new and critical revision of the argument leading to charge quantization on arbitrary spacetimes. The main differences of our approach with respect to previous works appear on spacetimes with non trivial torsion elements on its second integral cohomology group. We show that in these spacetimes there can be topologically non-trivial configurations of charged fields which do not imply charge quantization. However, the existence of a non-exact electromagnetic field always implies the quantization of charges. Another consequence of the theory for spacetimes with torsion is the fact that it gives rise to two natural quantization units that could be identified with the electric quantization unit (realized inside the quarks) and with the electron charge. In this framework the color charge can have a topological origin, with the number of colors being related to the order of the torsion subgroup. Finally, we discuss the possibility that the quantization of charge may be due to a weak non-exact component of the electromagnetic field extended over cosmological scales.Comment: Latex2e, 24 pages, no figure

Quaternion Gravi-Electromagnetism

Defining the generalized charge, potential, current and generalized fields as complex quantities where real and imaginary parts represent gravitation and electromagnetism respectively, corresponding field equation, equation of motion and other quantum equations are derived in manifestly covariant manner. It has been shown that the field equations are invariant under Lorentz as well as duality transformations. It has been shown that the quaternionic formulation presented here remains invariant under quaternion transformations.Comment: Key Words: Quaternion, dyons, gravito-dyons, gravi-electromagnetism. PACS No.: 04.90. +e ; 14.80. H