232 research outputs found
Methane and nitrous oxide fluxes in two coastal wetlands in the northeastern Gulf of Bothnia, Baltic Sea
Characteristics of outdoor falls among older people: A qualitative study
Background Falls are a major threat to older peopleâs health and wellbeing. Approximately half of falls occur in outdoor environments but little is known about the circumstances in which they occur. We conducted a qualitative study to explore older peopleâs experiences of outdoor falls to develop understanding of how they may be prevented. Methods We conducted nine focus groups across the UK (England, Wales, and Scotland). Our sample was from urban and rural settings and different environmental landscapes. Participants were aged 65+ and had at least one outdoor fall in the past year. We analysed the data using framework and content analyses. Results Forty-four adults aged 65 â 92 took part and reported their experience of 88 outdoor falls. Outdoor falls occurred in a variety of contexts, though reports suggested the following scenarios may have been more frequent: when crossing a road, in a familiar area, when bystanders were around, and with an unreported or unknown attribution. Most frequently, falls resulted in either minor or moderate injury, feeling embarrassed at the time of the fall, and anxiety about falling again. Ten falls resulted in fracture, but no strong pattern emerged in regard to the contexts of these falls. Anxiety about falling again appeared more prevalent among those that fell in urban settings and who made more visits into their neighbourhood in a typical week. Conclusions This exploratory study has highlighted several aspects of the outdoor environment that may represent risk factors for outdoor falls and associated fear of falling. Health professionals are recommended to consider outdoor environments as well as the home setting when working to prevent falls and increase mobility among older people
Sensitivity, specificity, inclusivity and exclusivity of the updated Aptima Combo 2 assay, which provides detection coverage of the new diagnostic-escapeChlamydia trachomatisvariants
Background Four new variants ofChlamydia trachomatis(nvCTs), detected in several countries, cause false-negative or equivocal results using the Aptima Combo 2 assay (AC2; Hologic). We evaluated the clinical sensitivity and specificity, as well as the analytical inclusivity and exclusivity of the updated AC2 for the detection of CT andNeisseria gonorrhoeae(NG) on the automated Panther system (Hologic). Methods We examined 1004 clinical AC2 samples and 225 analytical samples spiked with phenotypically and/or genetically diverse NG and CT strains, and other potentially cross-reacting microbial species. The clinical AC2 samples included CT wild type (WT)-positive (n = 488), all four described AC2 diagnostic-escape nvCTs (n = 170), NG-positive (n = 214), and CT/NG-negative (n = 202) specimens. Results All nvCT-positive samples (100%) and 486 (99.6%) of the CT WT-positive samples were positive in the updated AC2. All NG-positive, CT/NG-negative,Trichomonas vaginalis(TV)-positive, bacterial vaginosis-positive, andCandida-positive AC2 specimens gave correct results. The clinical sensitivity and specificity of the updated AC2 for CT detection was 99.7 and 100%, respectively, and for NG detection was 100% for both. Examining spiked samples, the analytical inclusivity and exclusivity were 100%, i.e., in clinically relevant concentrations of spiked microbe. Conclusions The updated AC2, including two CT targets and one NG target, showed a high sensitivity, specificity, inclusivity and exclusivity for the detection of CT WT, nvCTs, and NG. The updated AC2 on the fully automated Panther system offers a simple, rapid, high-throughput, sensitive, and specific diagnosis of CT and NG, which can easily be combined with detection ofMycoplasma genitaliumand TV.Peer reviewe
Sensitivity, specificity, inclusivity and exclusivity of the updated Aptima Combo 2 assay, which provides detection coverage of the new diagnostic-escapeChlamydia trachomatisvariants
Background Four new variants ofChlamydia trachomatis(nvCTs), detected in several countries, cause false-negative or equivocal results using the Aptima Combo 2 assay (AC2; Hologic). We evaluated the clinical sensitivity and specificity, as well as the analytical inclusivity and exclusivity of the updated AC2 for the detection of CT andNeisseria gonorrhoeae(NG) on the automated Panther system (Hologic). Methods We examined 1004 clinical AC2 samples and 225 analytical samples spiked with phenotypically and/or genetically diverse NG and CT strains, and other potentially cross-reacting microbial species. The clinical AC2 samples included CT wild type (WT)-positive (n = 488), all four described AC2 diagnostic-escape nvCTs (n = 170), NG-positive (n = 214), and CT/NG-negative (n = 202) specimens. Results All nvCT-positive samples (100%) and 486 (99.6%) of the CT WT-positive samples were positive in the updated AC2. All NG-positive, CT/NG-negative,Trichomonas vaginalis(TV)-positive, bacterial vaginosis-positive, andCandida-positive AC2 specimens gave correct results. The clinical sensitivity and specificity of the updated AC2 for CT detection was 99.7 and 100%, respectively, and for NG detection was 100% for both. Examining spiked samples, the analytical inclusivity and exclusivity were 100%, i.e., in clinically relevant concentrations of spiked microbe. Conclusions The updated AC2, including two CT targets and one NG target, showed a high sensitivity, specificity, inclusivity and exclusivity for the detection of CT WT, nvCTs, and NG. The updated AC2 on the fully automated Panther system offers a simple, rapid, high-throughput, sensitive, and specific diagnosis of CT and NG, which can easily be combined with detection ofMycoplasma genitaliumand TV.Peer reviewe
Chlamydia trachomatis samples testing falsely negative in the Aptima Combo 2 test in Finland, 2019
Since February 2019, over 160 Chlamydia trachomatis (CT) cases testing negative or equivocal by Aptima Combo 2 (AC2) but positive by Aptima CT test run with Panther instruments occurred in Finland. The AC2 test targets chlamydial 23S rRNA while the CT test targets 16S rRNA. Sequencing of 10 strains revealed a nucleotide substitution in 23S rRNA. The significance of this for the failure of the AC2 test to detect the variant is not yet known.Peer reviewe
The first human report of mobile colistin resistance gene, mcr-1, in Finland
Colistin resistance mediated by mobile mcr-1 gene has raised concern during the last years. After steep increase in mcr-1 reports, other mcr-gene variants (mcr-2 to mcr-5) have been revealed as well. In 2016, a clinical study was conducted on asymptomatic stool carriage of extended spectrum beta-lactamase (ESBL) producing Escherichia coli and Klebsiella pneumoniae among Finnish adults. All suspected ESBL producing bacterial isolates were first tested by phenotypic ESBL-confirmation methods, and then further analyzed with whole genome sequencing to identify the resistance genes. We found one study subject carrying a colistin resistant E.coli with a transferrable mcr-1 gene. This multi-drug resistant isolate, although initially suspected to be an ESBL producer, did not carry any ESBL genes, but was proven to carry several other resistance genes by using whole genome sequencing. Sequence type was ST93. The mcr-1 gene was connected to IncX4 plasmid which suggests that the colistin resistance gene locates in the respective plasmid. Here, we report the finding of a mcr-1 harboring human E.coli isolate from Finland. Clinical antimicrobial resistance (AMR) rates are low in Finland, and mobile colistin resistance has not been reported previously. This highlights the importance of AMR surveillance also in populations with low levels of resistance
ItÀmeren kalan ja muun kotimaisen kalan ympÀristömyrkyt: PCDD/F-, PCB-, PBDE-, PFCja OT-yhdisteet : EU-kalat ll
EU-KALAT II hankkeessa tuotettiin tietoa ItĂ€meren kalojen ja kotimaisten jĂ€rvikalojen sekĂ€ kasvatettujen kalojen PCDD/F- ja PCB- sekĂ€ PBDE-pitoisuuksista eri ikĂ€isissĂ€ ja kokoisissa kaloissa sekĂ€ lajeittain ettĂ€ alueittain. Hankkeessa tutkittiin myös perfluorattuja yhdisteitĂ€ (PFC) ja organotina (OT)-yhdisteitĂ€ sekĂ€ lihaksesta ettĂ€ maksasta. Tutkimuksesta saatiin uutta tietoa kalojen haitallisten aineiden pitoisuuksista riskinhallintaa varten. Vuoden 2009 tuloksia verrattiin aikaisempiin tuloksiin vuosilta 2002-2003. ItĂ€meren ja muun kotimaisen kalan PCDD/F- ja PCB-pitoisuuksista nousevat esiin samat kalalajit, joiden on aiemminkin todettu kerÀÀvĂ€n nĂ€itĂ€ ympĂ€ristömyrkkyjĂ€. Silakka, lohi ja meritaimen sekĂ€ nahkiainen ja tĂ€ssĂ€ hankkeessa lisĂ€ksi kampela Kotkan alueelta ylittĂ€vĂ€t PCDD/F- ja PCB-yhdisteille asetetut enimmĂ€ispitoisuusrajat. ItĂ€meren kaloista, kilohailin, muikun, ahvenen, hauen, kuhan, mateen ja turskan dioksiinien mediaanipitoisuudet eivĂ€t yllĂ€ edes puoleen sallitusta enimmĂ€ispitoisuudesta, joka on 4 pg/g tuorepainoa. Kun verrataan vuoden 2002-2003 pitoisuuksia vuoden 2009 PCDD/F- ja PCB- sekĂ€ PBDE-yhdisteiden pitoisuuksiin, ovat lohen ja silakan keskimÀÀrĂ€iset pitoisuudet pienentyneet. Avomerialueiden OT-pitoisuudet lihaksessa olivat noin kolmanneksen pienemmĂ€t kuin vuonna 2005â2007 pyydetyissĂ€ nĂ€ytteissĂ€. Pahimpia ItĂ€meren ympĂ€ristömyrkkyjĂ€ ovat edelleen dioksiinit ja dioksiininkaltaiset PCB-yhdisteet. PBDE- ja PFOS- ja OTpitoisuudet ovat pieniĂ€ muutamaa poikkeusta lukuun ottamatta. Useista kalalajeista suurimmat haitta-aineiden pitoisuudet todettiin seuraavilta alueilta: SelkĂ€mereltĂ€ Porin edusta ja Turun ja Kotkan pyyntialueet sekĂ€ kaikkein pahimpana Helsingin Vanhankaupunginlahti, jossa sekĂ€ OT- ettĂ€ PFOS-pitoisuudet antavat aihetta suositella kulutuksen rajoittamista, ainakin isojen ahventen osalta
Levels of organic tin compounds in Baltic sea and Finnish fresh water fish
Orgaanisten tinayhdisteiden (OT) pitoisuuksia kotimaisessa meri- ja jÀrvikalassa
alettiin tutkia kattavasti, kun Helsingin uuden suursataman rakentamisen
yhteydessÀ vuonna 2005 mitattiin kalasta ja sedimentistÀ suuria
OT-pitoisuuksia. Tutkimuksessa keskityttiin niihin sisÀvesi- ja merikaloihin,
joita suomalaiset pÀÀsÀÀntöisesti kÀyttÀvÀt ravinnokseen. NÀytteitÀ kerÀttiin
sekÀ kuormitetuilta satama- ja teollisuusalueilta ettÀ alueilta, joilla ei
ole paikallista kuormitusta.
SisĂ€vesillĂ€ kalojen OT-pitoisuudet jĂ€ivĂ€t yleensĂ€ alle 10 ÎŒg/kg tuorepaino
(tp), mutta neljÀllÀ paikkakunnalla (Varkaus, Lohja, JyvÀskylÀ ja Tampere)
pitoisuudet olivat 19â28 ÎŒg/kg. Varkauden Huruslahden sedimentistĂ€ mitattiin
hankkeen yhteydessĂ€ 2â6 cm:n syvyydeltĂ€ jopa 35000 ÎŒg/kg kuivapaino
(kp) pitoisuus.
Merialueiden kaloissa OT-pitoisuudet olivat noin 10 kertaa suurempia kuin
sisÀvesillÀ. Merialueilla, joilla ei ole paikallista kuormitusta, OT-pitoisuudet
kaloissa olivat alle 20 ÎŒg/kg tp. Kuormitetuilla alueilla pitoisuudet ylittivĂ€t
40 ÎŒg/kg. Pahasti saastuneilta alueilta löydettiin 150â500 ÎŒg/kg pitoisuuksia.
Suurimmat OT-pitoisuudet todettiin Helsingin Vanhankaupunginlahden
ahvenista (28â528 ÎŒg/kg), joilla sekĂ€ pituus ettĂ€ paino korreloivat OT-pitoisuuden
kanssa. Suuria pitoisuuksia todettiin myös Naantalin satamassa, jossa
pitoisuudet kuitenkin pienenivÀt nopeasti avomerelle siirryttÀessÀ.
OT-pitoisuudet vaihtelivat samoilta pyyntialueilta kerÀttyjen kalalajien vÀlillÀ.
Ahvenesta, lahnasta ja kuhasta, jotka viihtyvÀt saaristossa ja sisÀlahdissa,
mitattiin keskimÀÀrin suurempia pitoisuuksia kuin silakasta, lohesta ja
kilohailista, jotka viihtyvÀt lÀhinnÀ avomerellÀ.Man beslöt undersöka halterna organiska tennföreningar (OT) i inhemsk
havs- och insjöfisk pÄ bred front dÄ stora OT-halter i fisk och sediment uppmÀttes
Ă„r 2005 i samband med byggandet av den nya storhamnen i Helsingfors.
I undersökningen koncentrerade man sig pÄ sÄdan insjö- och havsfisk,
som finlÀndare i regel anvÀnder som föda. Prover samlades in sÄvÀl
i belastade hamn- och industriomrÄden som i omrÄden utan lokal belastning.
I insjövatten stannade OT-halterna i fisk i allmĂ€nhet under 10 ÎŒg/kg fĂ€rsk
vikt (fv), men pÄ fyra orter (Varkaus, Lojo, JyvÀskylÀ och Tammerfors) var
halterna 19â28 ÎŒg/kg. I sedimentet i Huruslahti i Varkaus uppmĂ€ttes i samband
med projektet pĂ„ 2â6 cm djup halter pĂ„ hela 35000 ÎŒg/kg (torrvikt).
I fisk i havsomrÄden var OT-halterna cirka 10 gÄnger högre Àn i insjöfisk. I
havsomrĂ„den utan lokal belastning var OT-halterna i fisk under 20 ÎŒg/kg fv.
I belastade omrĂ„den översteg halterna 40 ÎŒg/kg. I svĂ„rt förorenade omrĂ„den
pĂ„trĂ€ffades halter pĂ„ 150â500 ÎŒg/kg. De högsta OT-halterna pĂ„trĂ€ffades
i abborrar i Gammelstadsviken i Helsingfors (28â528 ÎŒg/kg), hos vilka
sÄvÀl lÀngden som vikten korrelerade med OT-halten. Höga halter pÄtrÀffades
ocksÄ i hamnen i NÄdendal, dÀr de ÀndÄ snabbt sjönk allt efter som man
förflyttade sig lÀngre ut mot öppet hav.
OT-halterna varierade mellan fiskar insamlade i samma fÄngstomrÄden. Hos
abborre, braxen och gös som trivs i skÀrgÄrden och innervikar uppmÀttes
i genomsnitt högre halter Àn hos strömming, lax och vassbuk som frÀmst
trivs i öppet hav.The decision to launch an extensive study on the levels of organic tin
compounds (OTC) in Finnish fresh water and sea fish was made when high
levels of OTC were found in fish and in the sediment in connection with
the construction project of the new harbour in Helsinki in 2005. The study
focused on the fresh water and sea fish species that Finns mainly use as
food. Samples were collected both in harbour and industrial areas with OTC
contamination and in areas with no local contamination.
OTC content in fresh water fish usually remained under 10 ÎŒg/kg fresh
weight (fw), but contents measured in four municipalities (Varkaus, Lohja,
JyvĂ€skylĂ€ and Tampere) were 19â28 ÎŒg/kg. OTC content of as high as
35,000 ÎŒg/kg (dry weight) was measured in the sediment in Huruslahti
Bay, Varkaus, at the depth of 2â6 cm.
Sea fish showed OTC levels about ten times higher than fresh water
areas. OTC content in fish was under 20 ÎŒg/kg fw in sea areas with no
local contamination. Contents in contaminated areas exceeded 40 ÎŒg/kg.
Contents of 150â500 ÎŒg/kg were found in severely contaminated areas.
The highest OTC contents (28â528 ÎŒg/kg) were found in perch caught in
Vanhankaupunginlahti Bay in Helsinki. In this case, both the length and
weight of fish correlated with the OTC content. High OTC levels were also
found in the Naantali Harbour where the level decreased rapidly when
moving towards the open sea.
The OTC levels in fish caught in the same area varied between different
species. Levels found in perch, bream and pike-perch, the preferred habitats
of which are in the archipelago and inland bays, were on average higher
than levels found in herring, salmon and sprat, which live in the open sea
No evidence of the role of early chemical exposure in the development of ÎČ-cell autoimmunity
Exposure to environmental chemicals can modulate the developing immune system, but its role in the pathogenesis of type 1 diabetes is largely unexplored. Our objective was to study the levels of circulating concentrations of environmental pollutants during the first years of life and their associations with the later risk of diabetes-predictive autoantibodies. From two birth-cohort studies including newborn infants with HLA-conferred susceptibility to type 1 diabetes (FINDIA and DIABIMMUNE), we identified case children with at least one biochemical diabetes-associated autoantibody (nâ=â30â40) and from one to four autoantibody-negative controls per each case child matched for age, gender, diabetes-related HLA-risk, delivery hospital, and, in FINDIA, also dietary intervention group. Plasma levels of 13 persistent organic pollutants and 14 per- and polyfluorinated substances were analyzed in cord blood and plasma samples taken at the age of 12 and 48 months. Both breastfeeding and the geographical living environment showed association with circulating concentrations of some of the chemicals. Breastfeeding-adjusted conditional logistic regression model showed association between decreased plasma HBC concentration at 12-month-old children and the appearance of diabetes-associated autoantibodies (HR, 0.989; 95% Cl, 0.978â1.000; Pâ=â0.048). No association was found between the plasma chemical levels and the development of clinical type 1 diabetes. Our results do not support the view that exposure to the studied environmental chemicals during fetal life or early childhood is a significant risk factor for later development of ÎČ-cell autoimmunity and type 1 diabetes.</p
ItÀmeren kalan ja muun kotimaisen kalan ympÀristömyrkyt: PCDD/F-, PCB-, PBDE-, PFC- ja OT-yhdisteet : EU-kalat II
EU-KALAT II hankkeessa tuotettiin tietoa ItÀmeren kalojen ja kotimaisten
jÀrvikalojen sekÀ kasvatettujen kalojen PCDD/F- ja PCB- sekÀ PBDE-pitoisuuksista
eri ikÀisissÀ ja kokoisissa kaloissa sekÀ lajeittain ettÀ alueittain.
Hankkeessa tutkittiin myös perfluorattuja yhdisteitÀ (PFC) ja organotina
(OT)-yhdisteitÀ sekÀ lihaksesta ettÀ maksasta. Tutkimuksesta saatiin uutta
tietoa kalojen haitallisten aineiden pitoisuuksista riskinhallintaa varten.
Vuoden 2009 tuloksia verrattiin aikaisempiin tuloksiin vuosilta 2002-2003.
ItÀmeren ja muun kotimaisen kalan PCDD/F- ja PCB-pitoisuuksista nousevat
esiin samat kalalajit, joiden on aiemminkin todettu kerÀÀvÀn nÀitÀ ympÀristömyrkkyjÀ.
Silakka, lohi ja meritaimen sekÀ nahkiainen ja tÀssÀ hankkeessa
lisÀksi kampela Kotkan alueelta ylittÀvÀt PCDD/F- ja PCB-yhdisteille
asetetut enimmÀispitoisuusrajat. ItÀmeren kaloista, kilohailin, muikun, ahvenen,
hauen, kuhan, mateen ja turskan dioksiinien mediaanipitoisuudet
eivÀt yllÀ edes puoleen sallitusta enimmÀispitoisuudesta, joka on 4 pg/g
tuorepainoa. Kun verrataan vuoden 2002-2003 pitoisuuksia vuoden 2009
PCDD/F- ja PCB- sekÀ PBDE-yhdisteiden pitoisuuksiin, ovat lohen ja silakan
keskimÀÀrÀiset pitoisuudet pienentyneet. Avomerialueiden OT-pitoisuudet
lihaksessa olivat noin kolmanneksen pienemmĂ€t kuin vuonna 2005â2007
pyydetyissÀ nÀytteissÀ. Pahimpia ItÀmeren ympÀristömyrkkyjÀ ovat edelleen
dioksiinit ja dioksiininkaltaiset PCB-yhdisteet. PBDE- ja PFOS- ja OTpitoisuudet
ovat pieniÀ muutamaa poikkeusta lukuun ottamatta. Useista
kalalajeista suurimmat haitta-aineiden pitoisuudet todettiin seuraavilta
alueilta: SelkÀmereltÀ Porin edusta ja Turun ja Kotkan pyyntialueet sekÀ
kaikkein pahimpana Helsingin Vanhankaupunginlahti, jossa sekÀ OT- ettÀ
PFOS-pitoisuudet antavat aihetta suositella kulutuksen rajoittamista, ainakin
isojen ahventen osalta.As an outcome of the EU FISH II project, information was produced about
PCDD/F and PCB as well as PBDE levels in Baltic fish, domestic freshwater
fish and farmed fish. Variations in the levels were studied by age and size
of the fish as well as by species and areas. Analyses of the presence of
perfluorinated compounds (PFC) and organotin compounds (OT) in muscles
and liver were also carried out within the scope of the project. New data
on the content of hazardous substances in fish were obtained for use in
risk management. The 2009 results were compared with the results of
the previous project conducted in 2002-2003. Analyses of PCDD/F and
PCB levels in fish highlight the same species that have also previously
been found to be susceptible to accumulation of these environmental
toxins. Baltic herring, salmon and sea trout as well as river lamprey and
now in this study also European flounder in Kotka area show levels of
PCDD/F and PCB compounds exceeding the maximum stipulated limits.
In Baltic fish, the median levels of dioxin equivalents in sprat, vendace,
perch, pike, pike-perch, burbot and cod are not even half of the permitted
maximum level, which is 4 pg/g of fresh weight. The comparison of the
levels measured in 2002-2003 with the 2009 levels of PCDD/F and PCB
as well as PBDE compounds shows that the mean levels have decreased
in salmon and herring. The OT levels measured in the muscles of open
sea fish were about one third lower than in the fish samples caught in
2005â2007. Dioxins and dioxin-like PCB compounds are still the worst
contaminants in the Baltic Sea. The levels of PBDE, PFOS and OT were low,
with a few exceptions. The Bothnian Sea and the fishing areas of Pori,
Turku and Kotka took the lead in the contamination ranking, but the worst
area was Vanhankaupunginlahti Bay of Helsinki, where both OT and PFOS
levels give cause to recommend consumption restrictions, at least as far as
large perch are concerned.I projektet EU-FISK II producerades information om PCDD/F- och PCBjÀmte
PBDE-halterna i östersjöfisk och inhemsk insjöfisk och odlad fisk av
olika Älder och storlek sÄvÀl artvis som regionvis. I projektet undersöktes
ocksÄ sÄvÀl muskler som levern med tanke pÄ perfluorkolvÀten (PFC) som
organiska tennföreningar (OT). Undersökningen gav ny information om
halterna skadliga Àmnen i fisk med tanke pÄ riskhanteringen. Resultaten
frÄn Är 2009 jÀmfördes med de tidigare resultaten frÄn Ären 2002-2003. I
frÄga om PCDD/F- och PCB-halterna i östersjöfisk och annan inhemsk fisk
framhÀvs samma fiskarter som ocksÄ tidigare kontaterats samla pÄ sig
av dessa miljötoxiner. Strömming, lax och havsöring jÀmte nejonöga och
i detta projekt ocksÄ flundra frÄn KotkaomrÄdet överskred grÀnsvÀrdena
som faststÀllts för PCDD/F- och PCB-föreningar. Av östersjöfisken nÄr
medianhalterna dioxinekvivalenter i skarpsill, siklöja, abborre, gÀdda,
gös, lake och torsk inte ens upp till halva det tillÄtna grÀnsvÀrdet, som
Àr 4 pg/g fÀrskvikt. DÄ man jÀmför halterna Är 2002-2003 med halterna
PCDD/F- och PCB- jÀmte PBDE-föreningar Är 2009, har de genomsnittliga
halterna i lax och strömming minskat. OT-halterna i muskler i fisk frÄn
öppet havar Àr cirka en tredjedel mindre Àn i proverna frÄn fisk som fÄngats
Ă„r 2005â2007. Dioxinerna och de dioxinliknande PCB-föreningarna utgör
fortsĂ€ttningsvis de vĂ€rsta kontaminanterna i Ăstersjön. PBDE-, PFOS- och
OT-halterna var med nÄgra fÄ undantag smÄ. Som mest kontaminerade
framstod fiskeriomrĂ„dena Bottenhavet, Björneborg, Ă
bo och Kotka och
som det allra vÀrsta omrÄdet Gammelstadsviken i Helsingfors, dÀr sÄvÀl
OT- som PFOS-halterna ger orsak att rekommendera en begrÀnsing av
konsumtionen Ätminstone för stora abborrars del
- âŠ