3,363 research outputs found

    Crosstalks Between Myelinating Cells and the Axonal Cytoskeleton

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    Neurofilaments: Properties, Functions, and Regulation - Springer

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    Neuronal intermediate filaments are the most prominent cytoskeleton component of adult neurons in both central and peripheral nervous system. They include neurofilament triplet proteins, peripherin, α-internexin, nestin, and synemin. Although it was initially thought that neuronal intermediate filaments serve a primarily structural function, it has since been demonstrated that they constitute a dynamic network involved in neuronal differentiation, axon outgrowth, and regeneration. Finally, they emerged as a primary cause of some neurodegenerative diseases. Here, we focus on the properties, function, and regulation of neuronal intermediate filaments as well as their relationship to different neurodegenerative diseases

    Spin-polarized stable phases of the 2-D electron fluid at finite temperatures

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    The Helmholtz free energy F of the interacting 2-D electron fluid is calculated nonperturbatively using a mapping of the quantum fluid to a classical Coulomb fluid [Phys. Rev. Letters, vol. 87, 206404 (2001)]. For density parameters rs such that rs<~25, the fluid is unpolarized at all temperatures t=T/EF where EF is the Fermi energy. For lower densities, the system becomes fully spin polarized for t<~0.35, and partially polarized for 0.35<t< 2, depending on the density. At rs ~25-30, and t ~0.35, an ''ambispin'' phase where F is almost independent of the spin polarization is found. These results support recent claims, based on quantum Monte Carlo results, for a stable, fully spin-polarized fluid phase at T = 0 for rs larger than about 25-26.Comment: Latex manuscript (4-5 pages) and two postscript figures; see also http://nrcphy1.phy.nrc.ca/ims/qp/chandre/chnc

    Intermediate Filaments in Neurodegenerative Diseases

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    The Equation of State and the Hugoniot of Laser Shock-Compressed Deuterium

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    The equation of state and the shock Hugoniot of deuterium are calculated using a first-principles approach, for the conditions of the recent shock experiments. We use density functional theory within a classical mapping of the quantum fluids [ Phys. Rev. Letters, {\bf 84}, 959 (2000) ]. The calculated Hugoniot is close to the Path-Integral Monte Carlo (PIMC) result. We also consider the {\it quasi-equilibrium} two-temperature case where the Deuterons are hotter than the electrons; the resulting quasi-equilibrium Hugoniot mimics the laser-shock data. The increased compressibility arises from hot D+eD^+-e pairs occuring close to the zero of the electron chemical potential.Comment: Four pages; One Revtex manuscript, two postscipt figures; submitted to PR

    Structure of the Local-field factor of the 2-D electron fluid. Possible evidence for correlated scattering of electron pairs

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    The static local-field factor (LFF) of the 2-D electron fluid is calculated {\it nonperturbatively} using a mapping to a classical Coulomb fluid [\lbrackPhys. Rev. Lett., {\bf 87}, 206]\rbrack. The LFF for the paramagnetic fluid {\it differs markedly} from perturbation theory where a maximum near 2kFk_F is expected. Our LFF has a quasi-linear small-k region leading to a maximum close to 3kFk_F, in agreent with currently available quantum Monte Carlo data. The structure in the LFF and its dependence on the density and temperature are interpretted as a signature of correlated scattering of electron pairs of opposite spin.The lack of structure at 2kF2k_F implies weakened Friedel oscillations, Kohn anomalies etc.Comment: 4 pages, 3 figures, version 2 of condmat/0304034, see http://nrcphy1.phy.nrc.ca/ims/qp/chandre/chnc/ Changs in the text, figure 2 and updated reference

    Analysis of transition forms towards more ecologically-oriented farming: the case of organic farming and integrated crop protection

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    Interdisciplinary approaches developed concerning the conversion to organic farming show that the types of conversion trajectories can be differentiated on the basis of the progression of crop protection changes within a larger framework where relationships to other “objects” are transformed – the soil, products, rotations, work organisation, marketing, social networks and knowledge acquisition. In the case of integrated plant production, the extent of changes depends on the degree of recomposition of agronomic practices. This transition implies major knowledge acquisition that relies on the support and contribution of advisors and on the group dynamics that develop within a group of farmers. Transitions towards integrated crop protection are, by their nature, more reversible and therefore more fragile than the conversion to organic farming. This is due to the fact that they are not stabilised by a certification or by the market, and analysis shows that their sustainability is linked in part to their integration within a group dynamics

    Manufacturing cement-based materials and building products via extrusion: From laboratory to factory

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    Manufacturing is critical to the economies of the UK and many other countries in the rest of the world. However, manufacturing of cement-based materials and building products predominantly remains based on old batch processing such as casting and pressing technologies and this may limit the applications and performance of the materials and products formed. In this paper, research is reported on transforming manufacturing of precast cement-based materials and building products from in batches to continuous processes via extrusion. Techniques used for producing plastic products are transferred into manufacturing cement-based building products like flat and corrugated sheet tiles, down pipes, door/window frames, door panels, solid wall/facade panels, honeycomb wall/facade panels etc. at laboratory and factory scales. In combination with sustainable cementitious materials with low carbon and low energy as matrix, this enables sustainable building products with key characteristics required by the 21st century can be manufactured via extrusion. The cement-based building products extrusion technique has been successfully transferred to industry. For instance, fibre reinforced cement-based partition wall panels, with a honeycomb cross section as large as 600 mm wide and 90 mm high, have been produced by a continuous extrusion process in a precast concrete products factory in Hangzhou, China.European Commission Seventh Framework Programme, (grant agreement no. 262954) and from the Hong Kong Research Grants Council through grants 6091/00E, 6226/01E, 6273/03E and 6167/06
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