No Evidence for a Aystematic FEII Emission Line Redshift in Type 1 AGN

We test the recent claim by Hu et al. (2008) that FeII emission in Type 1 AGN shows a systematic redshift relative to the local source rest frame and broad-line Hbeta. We compile high s/n median composites using SDSS spectra from both the Hu et al. sample and our own sample of the 469 brightest DR5 spectra. Our composites are generated in bins of FWHM Hbeta and FeII strength as defined in our 4D Eigenvector 1 (4DE1) formalism. We find no evidence for a systematic FeII redshift and consistency with previous assumptions that FeII shift and width (FWHM) follow Hbeta shift and FWHM in virtually all sources. This result is consistent with the hypothesis that FeII emission (quasi-ubiquitous in type 1 sources) arises from a broad-line region with geometry and kinematics the same as that producing the Balmer lines.Comment: 12 pages, 1 table, 1 figure - accepted for publication in ApJ Letter

A systematic review and economic evaluation of subcutaneous and sublingual allergen immunotherapy in adults and children with seasonal allergic rhinitis

© Queen’s Printer and Controller of HMSO 2013Severe allergic rhinitis uncontrolled by conventional medication can substantially affect quality of life. Immunotherapy involves administering increasing doses of a specific allergen, with the aim of reducing sensitivity and symptomatic reactions. Recent meta-analyses have concluded that both subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT) are more effective than placebo in reducing symptoms. It is uncertain which route of administration is more effective and whether or not treatment is cost-effective.National Institute for Health Research Health Technology Assessment programm

Near-infrared oxygen airglow from the Venus nightside

Groundbased imaging and spectroscopic observations of Venus reveal intense near-infrared oxygen airglow emission from the upper atmosphere and provide new constraints on the oxygen photochemistry and dynamics near the mesopause (approximately 100 km). Atomic oxygen is produced by the Photolysis of CO2 on the dayside of Venus. These atoms are transported by the general circulation, and eventually recombine to form molecular oxygen. Because this recombination reaction is exothermic, many of these molecules are created in an excited state known as O2(delta-1). The airglow is produced as these molecules emit a photon and return to their ground state. New imaging and spectroscopic observations acquired during the summer and fall of 1991 show unexpected spatial and temporal variations in the O2(delta-1) airglow. The implications of these observations for the composition and general circulation of the upper venusian atmosphere are not yet understood but they provide important new constraints on comprehensive dynamical and chemical models of the upper mesosphere and lower thermosphere of Venus

A Machine-Checked Formalization of the Generic Model and the Random Oracle Model

Most approaches to the formal analyses of cryptographic protocols make the perfect cryptography assumption, i.e. the hypothese that there is no way to obtain knowledge about the plaintext pertaining to a ciphertext without knowing the key. Ideally, one would prefer to rely on a weaker hypothesis on the computational cost of gaining information about the plaintext pertaining to a ciphertext without knowing the key. Such a view is permitted by the Generic Model and the Random Oracle Model which provide non-standard computational models in which one may reason about the computational cost of breaking a cryptographic scheme. Using the proof assistant Coq, we provide a machine-checked account of the Generic Model and the Random Oracle Mode

Review of Injection Therapy Clinics Performed by Physiotherapists Working in Primary Care.

Objectives To determine painscores for injection therapy and to review the overall change in outcomes post injection for a variety of musculoskeletal injections compared with the previous audits of a NHS Primary care Physiotherapy injection clinic. Methods Subjects were assessed using a numerical rating scale between 0 to 10 before and 4 weeks post injection. Results All average painscale scores were reduced 4 weeks after injection for all conditions. There is an overall average reduction in pain on provoking activity of 45.7%. Trigger finger/thumb (65.0%) demonstrated the most significant reduction in pain. Contrary to a common patient perception, injection therapy is not an exceptionally painful experience, with an average score of 3.2. Discussion Results are comparable with previous scores for injections carried out within the same NHS Primary care Physiotherapy clinic

Study into Average Civil Compensation in Mesothelioma Cases

The research provides estimates of average civil compensation and legal costs for occupational mesothelioma cases. It was designed to inform the development of proposals by both the Department for Work and Pensions and the Ministry of Justice in relation to helping mesothelioma victims who cannot trace a liable employer to access compensation and to speed up the settlement process for all victims. Using a variety of measures, average compensation awarded ranged from £137,000 to £153,531 and average legal costs ranged from £22,000 to £28,407. The estimates were based on a survey of 2,334 mesothelioma claims settled between 2007 and 2012. Regression analysis was used to investigate how civil compensation awarded and legal costs varied with the characteristics of the claimant and features of the claim. It was found that civil compensation decreased with the claimant’s age (by around £3,500 per year) and grew over time between 2007 and 2012. Average civil compensation was higher in Scotland than in England and Wales, and also higher where court proceedings were issued and where the claimant was alive at settlement. The length of the case was not associated with the size of civil compensation. The regression analysis found that legal costs increased by £4, on average, for every additional £100 of compensation. Legal costs were higher if the claimant was younger, the claim was made in England and Wales rather than Scotland, the claim was made after 2008, court proceedings were issued, the duration of the case was longer and the claimant was deceased on award

VPLanet: The Virtual Planet Simulator

We describe a software package called VPLanet that simulates fundamental aspects of planetary system evolution over Gyr timescales, with a focus on investigating habitable worlds. In this initial release, eleven physics modules are included that model internal, atmospheric, rotational, orbital, stellar, and galactic processes. Many of these modules can be coupled simultaneously to simulate the evolution of terrestrial planets, gaseous planets, and stars. The code is validated by reproducing a selection of observations and past results. VPLanet is written in C and designed so that the user can choose the physics modules to apply to an individual object at runtime without recompiling, i.e., a single executable can simulate the diverse phenomena that are relevant to a wide range of planetary and stellar systems. This feature is enabled by matrices and vectors of function pointers that are dynamically allocated and populated based on user input. The speed and modularity of VPLanet enables large parameter sweeps and the versatility to add/remove physical phenomena to assess their importance. VPLanet is publicly available from a repository that contains extensive documentation, numerous examples, Python scripts for plotting and data management, and infrastructure for community input and future development.Comment: 75 pages, 34 figures, 10 tables, accepted to the Proceedings of the Astronomical Society of the Pacific. Source code, documentation, and examples available at https://github.com/VirtualPlanetaryLaboratory/vplane

The Need for Speed in Rodent Locomotion Analyses.

Locomotion analysis is now widely used across many animal species to understand the motor defects in disease, functional recovery following neural injury, and the effectiveness of various treatments. More recently, rodent locomotion analysis has become an increasingly popular method in a diverse range of research. Speed is an inseparable aspect of locomotion that is still not fully understood, and its effects are often not properly incorporated while analyzing data. In this hybrid manuscript, we accomplish three things: (1) review the interaction between speed and locomotion variables in rodent studies, (2) comprehensively analyze the relationship between speed and 162 locomotion variables in a group of 16 wild-type mice using the CatWalk gait analysis system, and (3) develop and test a statistical method in which locomotion variables are analyzed and reported in the context of speed. Notable results include the following: (1) over 90% of variables, reported by CatWalk, were dependent on speed with an average R2 value of 0.624, (2) most variables were related to speed in a nonlinear manner, (3) current methods of controlling for speed are insufficient, and (4) the linear mixed model is an appropriate and effective statistical method for locomotion analyses that is inclusive of speed-dependent relationships. Given the pervasive dependency of locomotion variables on speed, we maintain that valid conclusions from locomotion analyses cannot be made unless they are analyzed and reported within the context of speed