Current outlook: sustained growth, sustained inflation

A report on the May 4, 1990 meeting of the Fourth District Economists' Roundtable, at which participants predicted a stronger long-term growth rate for the national economy through 1991 and an inflation rate of about 4 percent.Economic conditions - United States

The economic outlook: growth weakens, inflation unchanged

A summation of the forecasts of 27 economists made at the January 26, 1990 meeting of the Fourth District Economists' Roundtable, with major emphasis on the inflation outlook, GNP growth, and capital spending.Economic conditions - United States ; Inflation (Finance)

Archaeological Testing to Determine the National Register Eligibility Status of 18 Prehistoric Sites on Camp Bowie, Brown County, Texas Volume 2

Between the fall of 1999 and the summer of 2001, archaeologists from the Center for Archaeological Research (CAR) at The University of Texas at San Antonio conducted National Register Eligibility testing on 18 prehistoric sites within Camp Bowie in Brown County, Texas. The work was conducted for the Texas Army National Guard. The sites were recommended for testing during an inventory survey of Camp Bowie conducted between 1993 and 1998 (Wormser and Sullo-Prewitt 2001). Sixteen of the 18 sites tested contained burned rock middens. It was on the basis of that feature type that these sites were recommended for testing. Two sites (41BR261 and 41BR276) lacked burned rock middens, but Wormser and Sullo-Prewitt (2001) recommended these sites for testing based on the presence of diagnostic projectile points and the potential for buried features. As burned rock middens were a major element of the recommendations, much of this report focused on understanding those feature types. In all, 19 middens were tested. On the basis of these testing efforts, CAR recommends that 12 sites (41BR65, 41BR87, 41BR228, 41BR246, 41BR250, 41BR253, 41BR420, 41BR433, 41BR473, 41BR478, 41BR492, and 41BR493) should be considered eligible for inclusion to the National Register of Historic Places and warrant designations as State Archeological Landmarks. Either avoidance of these locations, or some form of mitigation on portions of these sites, will be necessary. Our testing suggests that the remaining sites either lack clear evidence of significant data (41BR261 and 41BR276) or have data of questionable integrity (41BR415, 41BR441, 41BR474, and 41BR480). In these cases, CAR recommends that these sites are not eligible for inclusion to the National Register of Historic Places and they do not warrant designation as State Archeological Landmarks

124-Color Super-resolution Imaging by Engineering DNA-PAINT Blinking Kinetics

Optical super-resolution techniques reach unprecedented spatial resolution down to a few nanometers. However, efficient multiplexing strategies for the simultaneous detection of hundreds of molecular species are still elusive. Here, we introduce an entirely new approach to multiplexed super-resolution microscopy by designing the blinking behavior of targets with engineered binding frequency and duration in DNA-PAINT. We assay this kinetic barcoding approach in silico and in vitro using DNA origami structures, show the applicability for multiplexed RNA and protein detection in cells, and finally experimentally demonstrate 124-plex super-resolution imaging within minutes.We thank Martin Spitaler and the imaging facility of the MPI of Biochemistry for confocal imaging support

Exercise is delayed in critically ill patients: a five year observational study in an Australian tertiary intensive care unit

Duration of bed rest among critically ill patients in ICU has been associated with development of persistent weakness that can last for more than five years. Commencing early exercise interventions in ICU is likely to reduce critically ill patients’ physical dysfunction. However, critically ill patients often experience prolonged periods of bed rest and inactivity. This study examined the timing of commencement of exercise interventions, including sitting out of bed and upright mobilisation, following physiological stability in critically ill patients and describes key clinical outcomes. Participants included consecutive patients admitted for >48 hours to a 25-bed Australian mixed medical and surgical adult ICU between July 2009 and June 2014. Time taken for patients to achieve neurological, cardiorespiratory and cardiovascular (physiological) stability was calculated and timing of initial sitting out of bed and upright mobilisation was recorded. A small number of patients (n=206, 6.0%) did not achieve physiological stability. A substantial proportion of patients (n=1377, 40.1%) did not complete any mobilisation or sitting activities. For patients (n=1851, 53.9%) who did undertake mobilisation or sitting activities, activity commenced a median (IQR) of 3.6 (2.0, 7.7) days after ICU admission. This represented a median (IQR) delay after physiological stability of 2.3 (1.3, 4.4) days for mobilisation and 2.7 (1.5, 5.7) days for sitting. In-hospital mortality was 14.3% (n=491) for patients who did not participate in exercise interventions, compared to 2.6% (n=89) for patients who exercised whilst in ICU

An Archaeological Survey of 35 Acres Near Eagle Pass, Maverick County, Texas

On April 22 through 24, 1998, staff archaeologists from the Center for Archaeological Research (CAR) conducted a 100 percent pedestrian survey with limited shovel and backhoe testing on two parcels near Eagle Pass, Texas (Figure 1). The archaeological investigation was conducted at the request of the Eagle Pass Independent School District as part of a plan to construct two new elementary schools on the parcels (Figures 2 and 3). The purpose of the survey was to identify archaeological sites visible on the surface as well as areas where sites are potentially buried. CAR archaeologists recorded 27 isolated finds on the 20-acre parcel south of the city. On the 15-acre parcel north of the city they discovered and recorded one archaeological site, with an additional nine isolated finds (Figures 2 and 3). The site has been heavily disturbed due to natural and artificial causes; therefore CAR recommended that the planned construction should be allowed to proceed with no further consultation with the State Historical Preservation Office (SHPO) or the Texas Historical Commission (THC)

Archaeological Testing to Determine the National Register Eligibility Status of 18 Prehistoric Sites on Camp Bowie, Brown County, Texas Volume 1

Between the fall of 1999 and the summer of 2001, archaeologists from the Center for Archaeological Research (CAR) at The University of Texas at San Antonio conducted National Register Eligibility testing on 18 prehistoric sites within Camp Bowie in Brown County, Texas. The work was conducted for the Texas Army National Guard. The sites were recommended for testing during an inventory survey of Camp Bowie conducted between 1993 and 1998 (Wormser and Sullo-Prewitt 2001). Sixteen of the 18 sites tested contained burned rock middens. It was on the basis of that feature type that these sites were recommended for testing. Two sites (41BR261 and 41BR276) lacked burned rock middens, but Wormser and Sullo-Prewitt (2001) recommended these sites for testing based on the presence of diagnostic projectile points and the potential for buried features. As burned rock middens were a major element of the recommendations, much of this report focused on understanding those feature types. In all, 19 middens were tested. On the basis of these testing efforts, CAR recommends that 12 sites (41BR65, 41BR87, 41BR228, 41BR246, 41BR250, 41BR253, 41BR420, 41BR433, 41BR473, 41BR478, 41BR492, and 41BR493) should be considered eligible for inclusion to the National Register of Historic Places and warrant designations as State Archeological Landmarks. Either avoidance of these locations, or some form of mitigation on portions of these sites, will be necessary. Our testing suggests that the remaining sites either lack clear evidence of significant data (41BR261 and 41BR276) or have data of questionable integrity (41BR415, 41BR441, 41BR474, and 41BR480). In these cases, CAR recommends that these sites are not eligible for inclusion to the National Register of Historic Places and they do not warrant designation as State Archeological Landmarks

Critical Care Cycling Study (CYCLIST) trial protocol: a randomised controlled trial of usual care plus additional in-bed cycling sessions versus usual care in the critically ill

Introduction In-bed cycling with patients with critical illness has been shown to be safe and feasible, and improves physical function outcomes at hospital discharge. The effects of early in-bed cycling on reducing the rate of skeletal muscle atrophy, and associations with physical and cognitive function are unknown. Methods and analysis A single-centre randomised controlled trial in a mixed medical-surgical intensive care unit (ICU) will be conducted. Adult patients (n=68) who are expected to be mechanically ventilated for more than 48 hours and remain in ICU for a further 48 hours from recruitment will be randomly allocated into either (1) a usual care group or (2) a group that receives usual care and additional in-bed cycling sessions. The primary outcome is change in rectus femoris cross-sectional area at day 10 in comparison to baseline measured by blinded assessors. Secondary outcome measures include muscle strength, incidence of ICU-acquired weakness, handgrip strength, time to achieve functional milestones (sitting out of bed, walking), Functional Status Score in ICU, ICU Mobility Scale, 6 min walk test 1week postICU discharge, incidence of delirium and quality of life (EuroQol Five Dimensions questionnaire Five Levels scale). Quality of life assessments will be conducted post-ICU admission at day 10, 3 and 6 months after acute hospital discharge. Participants in the intervention group will complete an acceptability of intervention questionnaire. Ethics and dissemination Appropriate ethical approval from Metro South Health Human Research Ethics Committee has been attained. Results will be published in peer-reviewed publications and presented at scientific conferences to assist planning of future multicentre randomised controlled trials (if indicated) that will test in-bed cycling as an intervention to improve the physical, cognitive and health-related quality of life outcomes of patients with critical illness

The Single-Case Reporting Guideline In BEhavioural Interventions (SCRIBE) 2016 statement

We developed a reporting guideline to provide authors with guidance about what should be reported when writing a paper for publication in a scientific journal using a particular type of research design: the single-case experimental design. This report describes the methods used to develop the Single-Case Reporting guideline In BEhavioural interventions (SCRIBE) 2016. As a result of 2 online surveys and a 2-day meeting of experts, the SCRIBE 2016 checklist was developed, which is a set of 26 items that authors need to address when writing about single-case research. This article complements the more detailed SCRIBE 2016 Explanation and Elaboration article (Tate et al., 2016) that provides a rationale for each of the items and examples of adequate reporting from the literature. Both these resources will assist authors to prepare reports of single-case research with clarity, completeness, accuracy, and transparency. They will also provide journal reviewers and editors with a practical checklist against which such reports may be critically evaluated. We recommend that the SCRIBE 2016 is used by authors preparing manuscripts describing single-case research for publication, as well as journal reviewers and editors who are evaluating such manuscripts.Funding for the SCRIBE project was provided by the Lifetime Care and Support Authority of New South Wales, Australia. The funding body was not involved in the conduct, interpretation or writing of this work. We acknowledge the contribution of the responders to the Delphi surveys, as well as administrative assistance provided by Kali Godbee and Donna Wakim at the SCRIBE consensus meeting. Lyndsey Nickels was funded by an Australian Research Council Future Fellowship (FT120100102) and Australian Research Council Centre of Excellence in Cognition and Its Disorders (CE110001021). For further discussion on this topic, please visit the Archives of Scientific Psychology online public forum at http://arcblog.apa.org. (Lifetime Care and Support Authority of New South Wales, Australia; FT120100102 - Australian Research Council Future Fellowship; CE110001021 - Australian Research Council Centre of Excellence in Cognition and Its Disorders)Published versio