'Let's make lots of money': the determinants of performance in the recorded music sector

This research analyzes the performance of 467 record labels in eight European countries over a period of 13 years (2003-2015). The main goal is to explain a relative measure of profitability in terms of observed variables, although the nature of the dataset also allows us to include non-observed firm and country effects. To this end alternative models are estimated and three main research questions are tested, namely: (1) the effect of the dual structure of the recorded music market, in which a competitive segment and an oligopoly coexist; (2) the extent and source of the volatility of profits in record labels; and (3) the nonlinear impact of size on performance

Immune Response to SARS-CoV-2 Third Vaccine in Patients With Rheumatoid Arthritis Who Had No Seroconversion After Primary 2-Dose Regimen With Inactivated or Vector-Based Vaccines

Objective. The aim of this study was to assess the immune response after a third dose of SARS-CoV-2 vaccine in patients with rheumatoid arthritis (RA) with undetectable antibody titers after the primary regimen of 2 doses. Methods. Patients with RA with no seroconversion after 2 doses of SARS-CoV-2 vaccine and who received a third dose of either an mRNA or vector-based vaccine were included. Anti-SARS-CoV-2 IgG antibodies, neutralizing activity, and T cell responses were assessed after the third dose. Results. A total of 21 nonresponder patients were included. At the time of vaccination, 29% were receiving glucocorticoids and 85% biologic disease-modifying antirheumatic drugs (including 6 taking abatacept [ABA] and 4 taking rituximab [RTX]). The majority (95%) received the BNT162b2 vaccine and only one of them received the ChAdOx1 nCoV-19 vaccine. After the third dose, 91% of the patients presented detectable anti-SARS-CoV-2 IgG and 76% showed neutralizing activity. Compared to other treatments, ABA and RTX were associated with the absence of neutralizing activity in 4 out of 5 (80%) patients and lower titers of neutralizing antibodies (median 3, IQR 0-20 vs 8, IQR 4-128; P = 0.20). Specific T cell response was detected in 41% of all patients after the second dose, increasing to 71% after the third dose. The use of ABA was associated with a lower frequency of T cell response (33% vs 87%, P = 0.03). Conclusion. In this RA cohort, 91% of patients who failed to seroconvert after 2 doses of SARS-CoV-2 vaccine presented detectable anti-SARS-CoV-2 IgG after a third dose. The use of ABA was associated with a lower frequency of specific T cell response.Fil: Isnardi, Carolina A.. No especifíca;Fil: Cerda, Osvaldo L.. No especifíca;Fil: Landi, Margarita. Austral University Hospital; LiberiaFil: Cruces, Leonel Hernán. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas en Retrovirus y Sida. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas en Retrovirus y Sida; ArgentinaFil: Schneeberger, Emilce E.. No especifíca;Fil: Montoro, Claudia Calle. Austral University Hospital; LiberiaFil: Alfaro, María Agustina. No especifíca;Fil: Roldán, Brian M.. No especifíca;Fil: Gómez Vara, Andrea B.. No especifíca;Fil: Giorgis, Pamela. No especifíca;Fil: Ezquer, Roberto Alejandro. No especifíca;Fil: Crespo Rocha, María G. No especifíca;Fil: Reyes Gómez, Camila R.. No especifíca;Fil: de Los Ángeles Correa, Mária. No especifíca;Fil: Rosemffet, Marcos G.. No especifíca;Fil: Abarza, Virginia Carrizo. No especifíca;Fil: Pellet, Santiago Catalan. Austral University Hospital; LiberiaFil: Perandones, Miguel. No especifíca;Fil: Reimundes, Cecilia. Austral University Hospital; LiberiaFil: Longueira, Yesica Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas en Retrovirus y Sida. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas en Retrovirus y Sida; ArgentinaFil: Turk, Gabriela Julia Ana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas en Retrovirus y Sida. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas en Retrovirus y Sida; ArgentinaFil: Quiroga, María Florencia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas en Retrovirus y Sida. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas en Retrovirus y Sida; ArgentinaFil: Laufer, Natalia Lorna. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas en Retrovirus y Sida. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas en Retrovirus y Sida; ArgentinaFil: Quintana, Rosana Maris. No especifíca;Fil: de la Vega, María Celina. No especifíca;Fil: Kreplak, Nicolás. No especifíca;Fil: Pifano, Marina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Maid, Pablo. Austral University Hospital; LiberiaFil: Pons Estel, Guillermo J.. No especifíca;Fil: Citera, Gustavo. No especifíca

Determinants of Unlawful File Sharing: A Scoping Review

We employ a scoping review methodology to consider and assess the existing evidence on the determinants of unlawful file sharing (UFS) transparently and systematically. Based on the evidence, we build a simple conceptual framework to model the psychological decision to engage in UFS, purchase legally or do nothing. We identify social, moral, experiential, technical, legal and financial utility sources of the decision to purchase or to file share. They interact in complex ways. We consider the strength of evidence within these areas and note patterns of results. There is good evidence for influences on UFS within each of the identified determinants, particularly for self-reported measures, with more behavioral research needed. There are also indications that the reasons for UFS differ across media; more studies exploring media other than music are required

Pictures, teaching, marketing and languages: results of an innovative learning project based on pinhole photography

A pinhole photography exhibition, entitled Tinned Cities, was organised thanks to the collaboration between the University of Valencia and the London School of Economics. Students from both universities took part in an interdisciplinary project based on a real decision making process in the context of cultural management. The implementation of a market research by UV students determined the 23 pictures to be exhibited. Students at LSE were responsible for writing descriptions of each picture. Most of the pictures selected represent icon cities. In order to test students´ participation, motivation and satisfaction with this innovative project, we undertook a quantitative research. Results showed high levels of participation, motivation and satisfaction. Artistic black and white pinhole pictures have been successfully used as a pedagogical resource

Reproductive performance and progesterone secretion in estrus-induced Manchega ewes treated with hCG at the time of AI

Two experiments were conducted to determine the effects of supplementing hCG at insemination on the luteal function and reproductive performance in estrus-induced mature Manchega ewes. The first experiment was carried out under field conditions with 1560 ewes on 27 farms. After estrous synchronisation with progestagen sponges and eCG, cervical inseminations were performed between October and February (breeding season) on 665 ewes on 12 farms and between March and June (non-breeding season) on 895 ewes on 15 farms. In each period and within each farm, approximately half of the ewes received an i.m. injection of 500 IU hCG at the time of insemination. The other half remained untreated and served as controls. Neither fertility (hCG 44.2%; control 42.0%) nor prolificacy (hCG 1.57; control 1.54) were affected by hCG treatment. However, on farms where fertility in the control group was persistently low, fertility of the hCG treated ewes was increased by 7.6% relative to those not treated (P < 0.1). The second experiment was carried out on 64 ewes from an experimental flock. Estrus and ovulation were induced in all ewes as in experiment 1. Thirty-two ewes received a single i.m. injection of 500 IU hCG at the time of intrauterine insemination, while the other half were not treated. Plasma progesterone (P 4) concentrations was measured every 2 days over a 28 day period following insemination. Progesterone secretion in the inseminated pregnant ewes was not modified by the hCG administration. However, a tendency (P < 0.1) for higher P 4 concentrations from days 8 to 14 was observed in those ewes that had been treated with hCG, but that did not conceive at AI. Pregnancy (62.5% and 59.4%), fertility or number of ewes lambing/ewes inseminated (56.3% and 50.0%) and prolificacy (1.56 and 1.50) of the inseminated pregnant ewes did not differ between the hCG-treated and control ewes. In ewes that failed to conceive at AI and were mated at the next oestrus (return cycle), fertility was increased by 12.1% (P < 0.1) in those ewes that had previously been treated with hCG (58.3%), compared with those not treated (46.2%). Results indicate that hCG treatment did not improve reproductive performance in estrus-induced and AI'd Manchega ewes, but treatment may be beneficial in increasing fertility in ewes from farms with low fertility rates. © 2006 Elsevier B.V. All rights reserved

Live and prerecorded popular music consumption

Live and prerecorded popular music, Participation, Audiences, Cultural demand, Cultural capital, Bivariate probit model, D12, C25, Z10, Z11,