673 research outputs found

    Board composition, process, and activism: evidence within American firms

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    This study provided an empirical test of the effects of compositional and process variables on board activism. The attributes examined were functional area knowledge, independence, duality, and effort norms. The findings from this study provided support for the positive relationships between both functional area knowledge and effort norms and board activism. The strong relationship between effort norms and activism indicates the importance of process variables in board research and the need for additional research using process variables in a board context giving further insight into board activism and governance. Additionally, the relationship between functional area knowledge and board activism highlights how boards ability to meet cognitive demands is critical in board performance. These results as well as future research directions are examined in the discussion.board activism, board governance, board attributes, strategic management.

    A National Veterans Strategy: The Economic, Social and Security Imperative

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    This publication details the foundational logic supporting a call to action, related to a broad-based effort to articulate and institutionalize a National Veterans Strategy. We argue that coordinated, "whole-of-government" action toward this end is essential to meet the nation's most important economic, social, and security obligations. Furthermore, we contend that the second Obama administration, working in close collaboration with executive agencies, Congress, and the private sector, is well-positioned to act on what we perceive to be a historic opportunity -- capitalizing on both the foundations of veteran-focused policy and progress enacted over the past decade and the overwhelming public support for returning veterans and military families -- to craft and institutionalize a National Veterans Strategy.Our purpose is to provide a researched and logically-developed case for action that is grounded in this nation's social and cultural traditions and attuned to the practical realities of our contemporary economic and political climate

    Securing A Competitive Advantage: Leveraging the Rare, Valuable and Differentiating Attributes of Veteran Talent

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    This data brief summarizes the findings from the report Revisiting the Business Case for Hiring a Veteran

    Paper 2: Revisiting the Business Case for Hiring a Veteran: A Strategy for Cultivating Competitive Advantage

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    This paper responds to recent dialogue on measuring companies’ return on investment (ROI) for their veteran hiring programs. It also cautions industry leaders against fixating on any single or generalized benchmark for their veteran hiring programs

    Development of a computer program data base of a navigation aid environment for simulated IFR flight and landing studies

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    A general aviation single pilot instrument flight rule simulation capability was developed. Problems experienced by single pilots flying in IFR conditions were investigated. The simulation required a three dimensional spatial navaid environment of a flight navigational area. A computer simulation of all the navigational aids plus 12 selected airports located in the Washington/Norfolk area was developed. All programmed locations in the list were referenced to a Cartesian coordinate system with the origin located at a specified airport's reference point. All navigational aids with their associated frequencies, call letters, locations, and orientations plus runways and true headings are included in the data base. The simulation included a TV displayed out-the-window visual scene of country and suburban terrain and a scaled model runway complex. Any of the programmed runways, with all its associated navaids, can be referenced to a runway on the airport in this visual scene. This allows a simulation of a full mission scenario including breakout and landing

    Reflections on the journey: six short stories

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    One of the goals of the 2011 International Year of Chemistry is to celebrate the contributions of women to science. A question that has been frequently asked in this regard is... Why is it necessary to highlight women in the "age of equality"? The reasons are varied but the facts are that many women scientists worked in obscurity throughout the 19th and even well into the 20th century, sometimes publishing anonymously to be heard. This celebration of Women in Science is one way to recognize both the resiliency and passion of these women. As part of this celebration, Chemistry Central Journal's Thematic Series of "Women in Chemistry" includes this article describing the path several women took as they pursued chemistry careers spanning the latter part of the 20th century and into the early 21st century. Sharon Haynie, Nancy Jones, Cheryl Martin, Paula Olsiewski, Mary Roberts and Amber Hinkle each have unique story of their personal journey from childhood to adulthood. As you read these stories, listen generously, and feel free to share your own stories, comments and thoughts

    Circulating Exosomal microRNAs as Predictive Biomarkers of Neoadjuvant Chemotherapy Response in Breast Cancer

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    Background: Neoadjuvant chemotherapy (NACT) is an increasingly used approach for treatment of breast cancer. The pathological complete response (pCR) is considered a good predictor of disease-specific survival. This study investigated whether circulating exosomal microRNAs could predict pCR in breast cancer patients treated with NACT. Method: Plasma samples of 20 breast cancer patients treated with NACT were collected prior to and after the first cycle. RNA sequencing was used to determine microRNA profiling. The Cancer Genome Atlas (TCGA) was used to explore the expression patterns and survivability of the candidate miRNAs, and their potential targets based on the expression levels and copy number variation (CNV) data. Results: Three miRNAs before that NACT (miR-30b, miR-328 and miR-423) predicted pCR in all of the analyzed samples. Upregulation of miR-127 correlated with pCR in triple-negative breast cancer (TNBC). After the first NACT dose, pCR was predicted by exo-miR-141, while miR-34a, exo-miR182, and exo-miR-183 predicted non-pCR. A significant correlation between the candidate miRNAs and the overall survival, subtype, and metastasis in breast cancer, suggesting their potential role as predictive biomarkers of pCR. Conclusions: If the miRNAs identified in this study are validated in a large cohort of patients, they might serve as predictive non-invasive liquid biopsy biomarkers for monitoring pCR to NACT in breast cancer

    Python game design for children: Games and programming resources

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    This project is focused on helping middle and high school students learn how to program and think computationally. We are creating a set of resources that will be used by the students to understand programming, Python, and PyGames concepts. These resources will be used for teaching the two one-week summer camps through Clemson University\u27s Pre-Collegiate programs in June and July 2014. This camp has been offered at Georgia Tech and Clemson University for two summers using a drag and drop visual programming language to help students create games. The instructors have found that the camp attendees do not find the visual programming language to be challenging enough. Thus, we are designing curricula to teach introductory computing concepts with the Python and PyGames programming languages in a fun and creative way and to give students the opportunity to learn to design and program their own games. We are also designing and creating our own games as a way to learn the language and have examples for the kids in the camp to build upon. This project was initiated this semester and we will pilot resources this summer during the two weeks of camp. We will showcase the initial games and resources created for this project
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