User Guide: A Guide to Disability Statistics from the National Assessment of Educational Programs (NAEP)

Policymakers, service providers, disability advocacy groups and researchers use disability statistics for a wide variety of purposes. A common problem that these groups encounter is finding a data source, a disability definition and/or a statistical method that provides them with a disability statistic that is both relevant to their needs and useful. The mission of the Cornell StatsRRTC is to bridge the divide between the sources of disability data and the users of disability statistics. One product of this effort is a series of User Guides to national survey data sets that collect information on the disability population. The purpose of each of the User Guides is to provide disability data users with: 1. An easily accessible guide to the disability information available in the nationally representative survey; 2. Estimates of the population with a disability, the disability prevalence rate, and estimates of participation-related statistics; 3. A description of the unique features of the dataset that will help disability statistics users determine whether the dataset can provide them with the statistic that they need; and 4. A description of how the dataset compares to other national data that are used to describe the population with disabilities. This User Guide contains information on the National Assessment of Educational Programs (NAEP), also known as “the Nation\u27s Report Card.” Unlike the other data sources addressed by the User Guide Series, the NAEP focuses solely on children. As a result, the focus of this Guide will shift to the inclusion and accommodation of educational activities of children with disabilities, as opposed to adult employment and economic well-being, which are the focus of many of the other User Guide

Jet fuel property changes and their effect on producibility and cost in the U.S., Canada, and Europe

The effects of changes in properties and blending stocks on the refinery output and cost of jet fuel in the U.S., Canada, and Europe were determined. Computerized refinery models that minimize production costs and incorporated a 1981 cost structure and supply/demand projections to the year 2010 were used. Except in the West U.S., no changes in jet fuel properties were required to meet all projected demands, even allowing for deteriorating crude qualities and changes in competing product demand. In the West U.S., property changes or the use of cracked blendstocks were projected to be required after 1990 to meet expected demand. Generally, relaxation of aromatics and freezing point, or the use of cracked stocks produced similar results, i.e., jet fuel output could be increased by up to a factor of three or its production cost lowered by up to $10/cu m. High quality hydrocracked stocks are now used on a limited basis to produce jet fuel. The conversion of U.S. and NATO military forces from wide-cut to kerosene-based jet fuel is addressed. This conversion resulted in increased costs of several hundred million dollars annually. These costs can be reduced by relaxing kerosene jet fuel properties, using cracked stocks and/or considering the greater volumetric energy content of kerosene jet fuel

Translation of Diverse Aramid- And 1,3-Dicarbonyl-peptides by Wild Type Ribosomes in Vitro

Here, we report that wild type Escherichia coli ribosomes accept and elongate precharged initiator tRNAs acylated with multiple benzoic acids, including aramid precursors, as well as malonyl (1,3-dicarbonyl) substrates to generate a diverse set of aramid-peptide and polyketide-peptide hybrid molecules. This work expands the scope of ribozyme- and ribosome-catalyzed chemical transformations, provides a starting point for in vivo translation engineering efforts, and offers an alternative strategy for the biosynthesis of polyketide-peptide natural products

An integrated numerical model for investigating guided waves in impact-damaged composite laminates

This paper presents a novel numerical technique that combines predictions of impact-induced damage and subsequent ultrasonic guided-wave propagation in composite laminates, with emphasis on the development and verification of the modelling framework. Delamination and matrix cracking are considered in the modelling technique, which is validated by experimental measurements on a carbon-fibre/epoxy plate using a drop-weight impact tower and a scanning laser vibrometer. Good agreement has been found between simulations and experiments regarding the impact response and global-local wavefields. Effects of these two damage modes, damage extent and multiple impacts on guided waves are studied using the modelling tool. Matrix cracking leads to lower wavefield scattering compared with delamination, particularly in un-damaged regions. The modelling strategy can provide valuable guidelines for optimising health-monitoring arrangements on composite structures that are susceptible to impacts, and the guided-wave model can also be integrated with other numerical models for predicting internal flaws in composite laminates

A validation of Amazon Mechanical Turk for the collection of acceptability judgments in linguistic theory

Amazon’s Mechanical Turk (AMT) is a Web application that provides instant access to thousands of potential participants for survey-based psychology experiments, such as the acceptability judgment task used extensively in syntactic theory. Because AMT is a Web-based system, syntacticians may worry that the move out of the experimenter-controlled environment of the laboratory and onto the user-controlled environment of AMT could adversely affect the quality of the judgment data collected. This article reports a quantitative comparison of two identical acceptability judgment experiments, each with 176 participants (352 total): one conducted in the laboratory, and one conducted on AMT. Crucial indicators of data quality—such as participant rejection rates, statistical power, and the shape of the distributions of the judgments for each sentence type—are compared between the two samples. The results suggest that aside from slightly higher participant rejection rates, AMT data are almost indistinguishable from laboratory data

Draft genomes of two Artocarpus plants, jackfruit (A. heterophyllus) and breadfruit (A. altilis)

Two of the most economically important plants in the Artocarpus genus are jackfruit (A. heterophyllus Lam.) and breadfruit (A. altilis (Parkinson) Fosberg). Both species are long-lived trees that have been cultivated for thousands of years in their native regions. Today they are grown throughout tropical to subtropical areas as an important source of starch and other valuable nutrients. There are hundreds of breadfruit varieties that are native to Oceania, of which the most commonly distributed types are seedless triploids. Jackfruit is likely native to the Western Ghats of India and produces one of the largest tree-borne fruit structures (reaching up to 45 kg). To-date, there is limited genomic information for these two economically important species. Here, we generated 273 Gb and 227 Gb of raw data from jackfruit and breadfruit, respectively. The high-quality reads from jackfruit were assembled into 162,440 scaffolds totaling 982 Mb with 35,858 genes. Similarly, the breadfruit reads were assembled into 180,971 scaffolds totaling 833 Mb with 34,010 genes. A total of 2822 and 2034 expanded gene families were found in jackfruit and breadfruit, respectively, enriched in pathways including starch and sucrose metabolism, photosynthesis, and others. The copy number of several starch synthesis-related genes were found to be increased in jackfruit and breadfruit compared to closely-related species, and the tissue-specific expression might imply their sugar-rich and starch-rich characteristics. Overall, the publication of high-quality genomes for jackfruit and breadfruit provides information about their specific composition and the underlying genes involved in sugar and starch metabolism

Mechanical Forces Due to Lightning Strikes to Aircraft A Pseudo-Stereo DIC Technique for Measuring Full-Field Displacement

Abstract. One of the major considerations currently affecting the design of composite aircraft structures is the damage resulting from lightning attachment. Full-field measurements of the displacement of materials under lightning attachment would provide a greater understanding of the forces induced by the high current waveform. Furthermore the understanding of the forces involved would allow for the validation of finite element models to simulate the effects of lightning attachment, therefore aiding in the design of solutions to reduce damage to aircraft structures. The study aimed to develop a pseudo-stereo high speed digital image correlation technique in order to obtain full-field information during lightning attachment based on a 100kA initial strike over a 500μs duration, the most severe waveform experienced. The technique that was developed gave full-field measurements for a 550x550x2mm 6082-T6 aluminium panel under a 100kA lightning attachment. Two correlation measurements were recorded at 3000 and 5000 frames per second. The displacement results are comparative with the theory of a cylindrical pressure expansion arising from the acoustic shockwave on attachment to the material. Further developments to this system could allow for more reliable results and higher frame rates which can be used to develop finite element simulations based on measured physical data

Gene duplication and protein evolution in tick-host interactions

Ticks modulate their hosts' defense responses by secreting a biopharmacopiea of hundreds to thousands of proteins and bioactive chemicals into the feeding site (tick-host interface). These molecules and their functions evolved over millions of years as ticks adapted to blood-feeding, tick lineages diverged, and host-shifts occurred. The evolution of new proteins with new functions is mainly dependent on gene duplication events. Central questions around this are the rates of gene duplication, when they occurred and how new functions evolve after gene duplication. The current review investigates these questions in the light of tick biology and considers the possibilities of ancient genome duplication, lineage specific expansion events, and the role that positive selection played in the evolution of tick protein function. It contrasts current views in tick biology regarding adaptive evolution with the more general view that neutral evolution may account for the majority of biological innovations observed in ticks.The Economic Competitive Support Programme (30/01/V010) and the National Research Foundation (NRF) Incentive Funding (IFR2011032400016) for Rated Researchers (NRF-Mans). MdC was supported by an NRF/Department of Science and Technology—Professional Development Program (NRF/DST-PDP) studentship.http://www.frontiersin.org/Cellular_and_Infection_Microbiologyam2017Veterinary Tropical Disease

Chromosome evolution and the genetic basis of agronomically important traits in greater yam

The nutrient-rich tubers of the greater yam, Dioscorea alata L., provide food and income security for millions of people around the world. Despite its global importance, however, greater yam remains an orphan crop. Here, we address this resource gap by presenting a highly contiguous chromosome-scale genome assembly of D. alata combined with a dense genetic map derived from African breeding populations. The genome sequence reveals an ancient allotetraploidization in the Dioscorea lineage, followed by extensive genome-wide reorganization. Using the genomic tools, we find quantitative trait loci for resistance to anthracnose, a damaging fungal pathogen of yam, and several tuber quality traits. Genomic analysis of breeding lines reveals both extensive inbreeding as well as regions of extensive heterozygosity that may represent interspecific introgression during domestication. These tools and insights will enable yam breeders to unlock the potential of this staple crop and take full advantage of its adaptability to varied environments