2,479 research outputs found

    Using Community Based Participatory Action Research as Service-learning for Tribal College Students

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    This work reports the methodological approach used in a Community Based Participatory Research (CBPR) project that incorporated Northern Plains tribal college students from four different communities as data gatherers and co-researchers in their communities. We report preliminary findings of perceptions of service learning among the participating tribal college students based on reflective interviews

    Clinical supervision in South Africa: Perceptions of supervision training, practices, and professional competencies

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    We investigated South African clinical and counselling psychology supervisors’ (n=44) perceptions of supervision training, their supervision experiences, and their perceived competence, confidence and effectiveness in providing supervision. Results indicated that many supervisors prematurely engage in supervision responsibilities and initiate supervision prior to receiving formal training in supervision. With limited regulatory guidelines available on supervision training and practices in South Africa, the findings indicate a need for the South African psychology profession to establish a formal regulatory framework on supervision training and practices. This includes identifying supervision training needs, developing training programmes, and instituting formal training requirements for practitioners who participate in clinical supervision.Significance: The sample of South African clinical and counselling psychologists involved in the supervision of trainee psychologists tended to engage in clinical supervision in advance of obtaining three years of independent clinical practice and prior to receiving appropriate training in providing supervision. There is a need for the Professional Board for Psychology of the Health Professions Council of South Africa (PBP-HPCSA) to appropriately monitor and enforce ethical obligations of psychologists who engage in supervision of trainee psychologists. Psychologists who provide clinical supervision to trainee psychologists ought to take personal responsibility for ensuring that they are appropriately trained and have acquired the necessary competencies to provide supervision before deciding to engage in supervision activities. Formal guidelines and policies regulating clinical supervision are necessary for ensuring psychology supervisors obtain appropriate training in supervision and fulfil mandatory HPCSA accredited supervision training requirements

    Unicorns and agency theory: Agreeable moral hazard?

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    The number of unicorns, startups valued over $1 billion, has steadily risen over the past decade. The abnormally high valuation of a unicorn from investors is based on their potential to disrupt a market and create a new paradigm. With this as the backdrop, this piece asks the question, what theoretical tools do we have to understand unicorns? Specifically, we explore agency theory. We argue that if principals and agents agree on the goal of disruption, then perhaps the agency problem that does occur in unicorns is beneficial, not a cost. Further, we argue that the principals of unicorns do want agents to take higher than normal risks with their investment to disrupt a given market. From this phenomenon, we introduce the concept of agreeable moral hazard and its use in the unicorn setting. Not only does the concept of agreeable moral hazard provide theoretical implications for future research, but it also highlights the need for more research to test existing theory on the unicorn population

    Why small firms are different: Addressing varying needs from boards of directors

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    Board of director member diversity has an impact on the functions each director successfully provides. Appropriate and necessary board member capabilities differ between small and large firms. Although these differences seem apparent, current research has favored studies related to large firms and neglected those related to board member needs of small firms. Grounded in Agency Theory and Resource Dependence Theory, the following manuscript theoretically suggests that firm size moderates the relationship between board member diversity and the two primary functions (monitoring and the provision of resources) of board members. Furthermore, small firms can enhance performance through appropriate member composition in differing ways than large firms

    The Histamine H4 Receptor Mediates Inflammation and Pruritus in Th2-Dependent Dermal Inflammation

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    The role of histamine H4 receptor (H4R) was investigated in a T-helper type 2 (Th2)-cell-mediated mouse skin inflammation model that mimics several of the features of atopic dermatitis. Treatment with two specific H4R antagonists before challenge with FITC led to a significant reduction in ear edema, inflammation, mast cell, and eosinophil infiltration. This was accompanied by a reduction in the levels of several cytokines and chemokines in the ear tissue. Upon ex vivo antigen stimulation of lymph nodes, H4R antagonism reduced lymphocyte proliferation and IL-4, IL-5, and IL-17 levels. One explanation for this finding is that lymph nodes from animals dosed with the H4R antagonist, JNJ 7777120, contained a lower number of FITC-positive dendritic cells. The effect of H4R antagonism on dendritic cell migration in vivo may be an indirect result of the reduction in tissue cytokines and chemokines or a direct effect on chemotaxis. In addition to anti-inflammatory effects, JNJ 7777120 also significantly inhibited the pruritus shown in the model. Therefore, the dual effects of H4R antagonists on pruritus and Th2-cell-mediated inflammation point to their therapeutic potential for the treatment of Th2-mediated skin disorders, including atopic dermatitis

    Development of Low-Cost Micromanipulation Systems for Small Extraterrestrial Samples

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    The analysis of microscale to mm-scale astromaterials often involves the transfer of samples from storage or collection substrates to analytical substrates. These transfers are accomplished by hand (via tweezers or fine-tipped needles) or by utilizing micromanipulation instruments. Freehand manipulation of small particles is extremely challenging due to involuntary hand tremors on the order of 100m and due to the triboelectric charging induced by frequent contact between the manipulation tool and the support substrate. Months or years of practice may be required before an investigator develops the necessary experience to confidently transfer a 10-20m particle in this manner. Handling even mm-sized particles with fine-tipped tweezers can be challenging, due to the inability to precisely control the force with which grains are being held. Mechanical, hydraulic, and motorized/electrical micromanipulators enable the precise handling of microscale samples and are often utilized in laboratories where frequent small sample preparation is required. However, the price of such instruments (~ 10,000to10,000 to 100,000) makes them cost-prohibitive for some institutions. Graduate students or early-career scientists interested in conducting research on interplanetary dust particles, Itokawa particles returned by Hayabusa, or future samples returned by OSIRIS-REx or Hayabusa2 may experience difficulty in justifying the expense of a micromanipulator to their advisors or principle investigators. Johnson Space Centers Astromaterials Acquisition and Curation Office and the Lunar and Planetary Institute conduct annual training for early career scientists and for investigators that require experience with handling of small extraterrestrial samples. In support of this training, we have been developing low-cost mechanical alternatives to expensive micromanipulators that training participants can implement in their respective facilities

    Do Cues Matter? Highly Inductive Settlement Cues Don't Ensure High Post-Settlement Survival in Sea Urchin Aquaculture

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    Increasing settlement and post-settlement survival during the critical transition from planktonic larvae to benthic juveniles will increase efficiency for sea urchin aquaculture. This study investigated the effects of temperature and settlement cues on the settlement and post-settlement survival of the sea urchin Tripneustes gratilla during this phase. The current commercial methodology, which utilises natural biofilm settlement plates, was tested and resulted in low settlement (<2%) and poor post-settlement survival (<1% of settled urchins). In laboratory trials, settlement was high and unaffected by temperatures between 24 and 30°C, but significantly decreased at 33°C. Development of spines, however, was significantly affected by temperatures over 29°C. Mirroring this result, post-settlement survival was optimal between 24–28°C. In laboratory assays, the macroalgae Sargassum linearifolium and Corallina officinalis, and seawater conditioned with these algae, induced significantly higher settlement (>90%) than a natural biofilm (∼25%). The addition of macroalgae-conditioned seawater to natural biofilm significantly increased settlement rates (>85%). Mixed consortia and single strains of bacteria isolated from macroalgae, biofilms and adult conspecifics all induced significant settlement, but at significantly lower rates than macroalgae. No evidence was found that higher rates of settlement to bacteria on macroalgae were generated by a cofactor from the macroalgae. Age of bacterial cultures, culturing bacteria on solid and liquid media and concentration of nutrients in cultures had little effect on settlement rates. Finally, macroalgae-conditioned seawater combined with natural biofilm settlement plates induced significantly higher settlement than to the biofilm plates alone in a commercial scale trial. However, high post-settlement mortality resulted in equivalent survival between treatments after 25 days. This study highlights that settlement studies should extend to post-settlement survival, which remains poor for T. gratilla and is a significant obstacle to increasing efficiency for aquaculture

    Investigating Astromaterials Curation Applications for Dexterous Robotic Arms

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    The Astromaterials Acquisition and Curation office at NASA Johnson Space Center is currently investigating tools and methods that will enable the curation of future astromaterials collections. Size and temperature constraints for astromaterials to be collected by current and future proposed missions will require the development of new robotic sample and tool handling capabilities. NASA Curation has investigated the application of robot arms in the past, and robotic 3-axis micromanipulators are currently in use for small particle curation in the Stardust and Cosmic Dust laboratories. While 3-axis micromanipulators have been extremely successful for activities involving the transfer of isolated particles in the 5-20 micron range (e.g. from microscope slide to epoxy bullet tip, beryllium SEM disk), their limited ranges of motion and lack of yaw, pitch, and roll degrees of freedom restrict their utility in other applications. For instance, curators removing particles from cosmic dust collectors by hand often employ scooping and rotating motions to successfully free trapped particles from the silicone oil coatings. Similar scooping and rotating motions are also employed when isolating a specific particle of interest from an aliquot of crushed meteorite. While cosmic dust curators have been remarkably successful with these kinds of particle manipulations using handheld tools, operator fatigue limits the number of particles that can be removed during a given extraction session. The challenges for curation of small particles will be exacerbated by mission requirements that samples be processed in N2 sample cabinets (i.e. gloveboxes). We have been investigating the use of compact robot arms to facilitate sample handling within gloveboxes. Six-axis robot arms potentially have applications beyond small particle manipulation. For instance, future sample return missions may involve biologically sensitive astromaterials that can be easily compromised by physical interaction with a curator; other potential future returned samples may require cryogenic curation. Robot arms may be combined with high resolution cameras within a sample cabinet and controlled remotely by curator. Sophisticated robot arm and hand combination systems can be programmed to mimic the movements of a curator wearing a data glove; successful implementation of such a system may ultimately allow a curator to virtually operate in a nitrogen, cryogenic, or biologically sensitive environment with dexterity comparable to that of a curator physically handling samples in a glove box

    Meca500 Robotic Arm Developments Towards Astromaterials Curation Applications

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    As a part of the ongoing efforts to develop new curation tools and techniques for astromaterials within the Astromaterials Acquisition and Curation office at NASAs Johnson Space Center, we are developing a variety of manually and electrically controlled micromanipulation systems. Most current techniques require manual manipulation, and in some cases the manipulation task is being done entirely freehand. The motorized systems avail-able are restricted to three degrees of freedom and use proprietary control systems. For example, the MicroSupport AxisPro manipulation system currently used in microscale particle experiments is limited in its range of motion, as it can only move the manipulators in a three axis Cartesian range over a predetermined area above microscope slides. While having an efficient user interface, the control system is proprietary and prevents custom development and optimization to extend the viable applications of the system. In order to address some of these limitations, we have been testing robotic designs with multiple degrees of freedom and of a variety of designs. We are currently investigating the Meca500 robotic arm by Mecademic as a potential manipulation system to overcome some of these obstacles
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