A Data Driven Frequency Based Method For Electrical-Mechanical Actuator Condition Monitoring

This research investigates a novel data driven approach to condition monitoring of Electro-Mechanical Actuators (EMAs) consisting of feature extraction and fault classification. Since many common faults in rotating machinery produce unique frequency components, the approach is based on signal analysis in the frequency domain of both inherent EMA signals and accelerometers. The feature extraction process exposes fault frequencies in signal data that are synchronous with motor position through a series of signal processing techniques consisting of digital re-sampling, Power Spectral Density (PSD) computation, and feature reduction. The resulting reduced dimension feature is then used to determine the condition of the EMA with a trained Bayesian Classifier. Signal data collected from EMAs in known health configurations is used to train the algorithms so that the condition of EMA’s with unknown health may be predicted. Laboratory results show that EMA condition can be determined over multiple non-steady operating conditions and is capable of isolating multiple faults that produce unique fault signatures

A Rare Case of Right Lower Lobe Intralobar Pulmonary Sequestration in an Adult

Pulmonary sequestration is a rare congenital abnormality which is often diagnosed in childhood. There are two types of sequestration which are differentiated by the presence, or lack of pleural lining dividing the aberrant lung tissue from functional lung. Data for the management of this pathology in adults remains scarce. Here we present a case of intralobar pulmonary sequestration in an adult. The management of this patient comprised of surgical treatment involving lobectomy and ligation of the feeding vessel. The patient had an uneventful recovery and final pathology revealed a chronic infection in the sequestration

Subcellular Targeting Domains of Sphingomyelin Synthase 1 and 2

Sphingomyelin synthase (SMS) sits at the crossroads of sphingomyelin (SM), ceramide, diacylglycerol (DAG) metabolism. It utilizes ceramide and phosphatidylcholine as substrates to produce SM and DAG, thereby regulating lipid messengers which play a role in cell survival and apoptosis. Furthermore, its product SM has been implicated in atherogenic processes such as retention of lipoproteins in the blood vessel intima. There are two mammalian sphingomyelin synthases: SMS1 and SMS2. SMS1 is found exclusively in the Golgi at steady state, whereas SMS2 exists in the Golgi and plasma membrane. Conventional motifs responsible for protein targeting to the plasma membrane or Golgi are either not present in, or unique to, SMS1 and SMS2. In this study, we examined how SMS1 and SMS2 achieve their respective subcellular localization patterns. Brefeldin A treatment prevented SMS1 and SMS2 from exiting the ER, demonstrating that they transit through the classical secretory pathway. We created truncations and chimeras of SMS1 and SMS2 to define their targeting signals. We found that SMS1 contains a C-terminal Golgi targeting signal and that SMS2 contains a C-terminal plasma membrane targeting signal

Control methods for Dermanyssus gallinae in systems for laying hens: results of an international seminar

This paper reports the results of a seminar on poultry red mite (PRM), Dermanyssus gallinae. Eighteen researchers from eight European countries discussed life cycle issues of the mite, effects of mites on hens and egg production, and monitoring and control methods for PRM in poultry facilities. It was determined that PRM probably causes more damage than envisaged, with the cost in The Netherlands alone reaching 11 million euro per annum. However a great deal is still unknown about PRM (e.g. reproduction, survival methods, etc.) and that PRM monitoring is an important instrument in recognising and admitting the problem and in taking timely measures. Currently, the most promising control method combines heating the hen house in combination with chemical treatments. Future areas of development which show promise include the use of entomopathogenic fungi, vaccination and predatory mites. The final aim is to solve the problem of D. gallinae in housing systems for laying hens

Family firm internationalization: Past research and an agenda for the future

Although the study of family firm internationalization has generated considerable scholarly attention, existing research has offered varied and at times incompatible findings on how family ownership and management shape internationalization. To improve our understanding of family firm internationalization, we systematically review 220 conceptual and empirical studies published over the past three decades, structuring our comprehensive overview of this field according to seven core international business (IB) themes. We assess the literature and propose directions for future research by developing an integrative framework of family firm internationalization that links IB theory with conceptual perspectives used in the reviewed body of work. We propose a research agenda that advocates a cross-disciplinary, multi-theoretic, and cross-level approach to studying family firm internationalization. We conclude that family firm internationalization research has the potential to contribute valuable insights to IB scholarship by increasing attention to conceptual and methodological issues, including micro-level affective motivations, background social institutions, temporal perspectives, and multi-level analyses

COVID-19 Outbreak and Physical Activity in the Italian Population : A Cross-Sectional Analysis of the Underlying Psychosocial Mechanisms

Italy is one of the first European epicenters of the COVID-19 pandemic. In attempts to hinder the spread of the novel coronavirus disease, Italian government hardened protective measures, from quarantine to lockdown, impacting millions of lives dramatically. Amongst the enacted restrictions, all non-essential activities were prohibited as well as all outdoor activities banned. However, at the first spur of the outbreak, for about a dozen of days, physical and sports activities were permitted, while maintaining social distancing. In this timeframe, by administering measures coming from self-determination theory and theory of planned behavior and anxiety state, in an integrated approach, we investigated the prevalence of these activities by testing, via a Structural Equation Model, the influence of such psychosocial variables on the intention to preserve physical fitness during the healthcare emergency. Through an adequate fit of the hypothesized model and a multi-group analysis, we compared the most COVID-19 hit Italian region \u2013 Lombardy \u2013 to the rest of Italy, finding that anxiety was significantly higher in the Lombardy region than the rest of the country. In addition, anxiety negatively influenced the intention to do physical activity. Giving the potential deleterious effects of physical inactivity due to personal restrictions, these data may increase preparedness of public health measures and attractiveness of recommendations, including on the beneficial effects of exercise, under circumstances of social distancing to control an outbreak of a novel infectious disease

Effort-reward imbalance and burnout among humanitarian aid workers

Objectives: This study examined stress-related working conditions – defined in terms of effort-reward imbalance (ERI) – and its association with burnout among a large, international sample of humanitarian aid workers. Methods: Descriptive statistics were applied on crosssectional survey data (N=1,980) to profile ERI and burnout and Pearson’s χ 2 tests used to characterize associated socio- and occupational-demographic factors. Associations between ERI and burnout were established using binary logistic regression to generate odds ratios and 95% confidence intervals adjusted for potential confounding variables. Results: For high emotional exhaustion, the prevalence rate was 36% for women and 27% for men; high depersonalisation, 9% and 10%; and low personal achievement, 47% and 31%. Intermediate and high ERI was associated with significantly increased odds of high emotional exhaustion, with mixed findings for depersonalisation and personal achievement. Conclusions: The ERI model was supported as a useful framework for investigating occupational correlates of burnout

Control methods for Dermanyssus gallinae in systems for laying hens: results of an international seminar

This paper reports the results of a seminar on poultry red mite (PRM), Dermanyssus gallinae. Eighteen researchers from eight European countries discussed life cycle issues of the mite, effects of mites on hens and egg production, and monitoring and control methods for PRM in poultry facilities. It was determined that PRM probably causes more damage than envisaged, with the cost in The Netherlands alone reaching 11 million euro per annum. However a great deal is still unknown about PRM (e.g. reproduction, survival methods, etc.) and that PRM monitoring is an important instrument in recognising and admitting the problem and in taking timely measures. Currently, the most promising control method combines heating the hen house in combination with chemical treatments. Future areas of development which show promise include the use of entomopathogenic fungi, vaccination and predatory mites. The final aim is to solve the problem of D. gallinae in housing systems for laying hen

Probing structural relaxation in complex fluids by critical fluctuations

Complex fluids, such as polymer solutions and blends, colloids and gels, are of growing interest in fundamental and applied soft-condensed-matter science. A common feature of all such systems is the presence of a mesoscopic structural length scale intermediate between atomic and macroscopic scales. This mesoscopic structure of complex fluids is often fragile and sensitive to external perturbations. Complex fluids are frequently viscoelastic (showing a combination of viscous and elastic behaviour) with their dynamic response depending on the time and length scales. Recently, non-invasive methods to infer the rheological response of complex fluids have gained popularity through the technique of microrheology, where the diffusion of probe spheres in a viscoelastic fluid is monitored with the aid of light scattering or microscopy. Here we propose an alternative to traditional microrheology that does not require doping of probe particles in the fluid (which can sometimes drastically alter the molecular environment). Instead, our proposed method makes use of the phenomenon of "avoided crossing" between modes associated with the structural relaxation and critical fluctuations that are spontaneously generated in the system.Comment: 4 pages, 4 figure

Dermanyssus gallinae in layer farms in Kosovo: a high risk for salmonella prevalence

Background The poultry red mite (PRM), Dermanyssus gallinae (D.g.) is a serious ectoparasitic pest of poultry and potential pathogen vector. The prevalence of D. g. and the prevalence of Salmonella spp. within mites on infested laying poultry farms were investigated in Kosovo. Findings In total, 14 populated layer farms located in the Southern Kosovo were assessed for D. g. presence. Another two farms in this region were investigated 6 months after depopulation. Investigated flocks were all maintained in cages, a common housing system in Kosovo. A total of eight farms were found to be infested with D. g. (50%) at varying levels, including the two depopulated farms. The detection of Salmonella spp. from D. g. was carried out using PCR. Out of the eight layer farms infested with D. g., Salmonella spp. was present in mites on three farms (37.5%). Conclusions This study confirms the high prevalence of D. g. in layer flocks in Kosovo and demonstrates the link between this mite and the presence of Salmonella spp. on infested farms