The Anthropocene: an Australasian perspective and survey.

In 2000, Crutzen and Stoermer suggested that the Holocene (the geological period of time since 11,700 years ago: Walker et al., 2009) had finished and that humanity had now entered the “Anthropocene”. As summarised by Steffen et al. (2011) and Wolfe et al. (2013), these scientists were referring to the Anthropocene as the interval of demonstrable human alteration of global biogeochemical cycles, beginning subtly in the late 18th Century following James Watt’s invention of the coal-fired steam engine, and accelerating markedly in the mid-20th Century (called “The Great Acceleration”)

A review of late Quaternary silicic and some other tephra formations from New Zealand: their stratigraphy, nomenclature, distribution, volume, and age.

The stratigraphic relationships and distribution of 36 named late Quaternary (≤c. 50 000 yr B P.) silicic tephra formations, erupted from 4 volcanic centres—Okataina, Taupo, Maroa, and Tuhua (Mayor Island)—are presented. The stratigraphy and status of several other named late Quaternary tephras are also discussed. This compilation brings together all the data, currently scattered through many publications, to make tephrostratigraphy more accessible and more easily used. The nomenclature of tephra formations is discussed and some rationalisations are suggested. The term “tephrology” is suggested as an appropriate title for the field of tephra studies. The deletion of grain-size (ash, lapi1li), shape (breccia), and lithologic (pumice) terms from all formation names is recommended, as is standardisation on a “Tephra Formation” formal Several tephra layers not previously formally named, or without designated type sections, are defined. The dominant ferromagnesian mineral assemblage of each tephra formation has been compiled as an aid to tephra identification. All available radiocarbon ages (384) on each tephra formation are presented, and each age is assessed for reliability in dating the eruption of that tephra. The standard-deviation weighted mean age of the reliable ages has been determined as the best current estimate of the age of each tephra. At least 10 tephra formations have no reliable ages, and efforts should be made to date thes

Re-identification of c. 15 700 cal yr BP tephra bed at Kaipo Bog, eastern North Island: implications for dispersal of Rotorua and Puketarata tephra beds.

A 10 mm thick, c. 15 700 calendar yr BP (c. 13 100 14C yr BP) rhyolitic tephra bed in the well-studied montane Kaipo Bog sequence of eastern North Island was previously correlated with Maroa-derived Puketarata Tephra. We revise this correlation to Okataina-derived Rotorua Tephra based on new compositional data from biotite phenocrysts and glass. The new correlation limits the known dispersal of Puketarata Tephra (sensu stricto, c. 16 800 cal yr BP) and eliminates requirements to either reassess its age or to invoke dual Puketarata eruptive events. Our data show that Rotorua Tephra comprises two glass-shard types: an early-erupted low-K2O type that was dispersed mostly to the northwest, and a high-K2O type dispersed mostly to the south and southeast, contemporary with late-stage lava extrusion. Late-stage Rotorua eruptives contain biotite that is enriched in FeO compared with biotite from Puketarata pyroclastics. The occurrence of Rotorua Tephra in Kaipo Bog (100 km from the source) substantially extends its known distribution to the southeast. Our analyses demonstrate that unrecognised syn-eruption compositional and dispersal changes can cause errors in fingerprinting tephra deposits. However, the compositional complexity, once recognised, provides additional fingerprinting criteria, and also documents magmatic and dispersal processes

Proof Theory, Transformations, and Logic Programming for Debugging Security Protocols

We define a sequent calculus to formally specify, simulate, debug and verify security protocols. In our sequents we distinguish between the current knowledge of principals and the current global state of the session. Hereby, we can describe the operational semantics of principals and of an intruder in a simple and modular way. Furthermore, using proof theoretic tools like the analysis of permutability of rules, we are able to find efficient proof strategies that we prove complete for special classes of security protocols including Needham-Schroeder. Based on the results of this preliminary analysis, we have implemented a Prolog meta-interpreter which allows for rapid prototyping and for checking safety properties of security protocols, and we have applied it for finding error traces and proving correctness of practical examples

Hydrodynamic induced deformation and orientation of a microscopic elastic filament

We describe simulations of a microscopic elastic filament immersed in a fluid and subject to a uniform external force. Our method accounts for the hydrodynamic coupling between the flow generated by the filament and the friction force it experiences. While models that neglect this coupling predict a drift in a straight configuration, our findings are very different. Notably, a force with a component perpendicular to the filament axis induces bending and perpendicular alignment. Moreover, with increasing force we observe four shape regimes, ranging from slight distortion to a state of tumbling motion that lacks a steady state. We also identify the appearance of marginally stable structures. Both the instability of these shapes and the observed alignment can be explained by the combined action of induced bending and non-local hydrodynamic interactions. Most of these effects should be experimentally relevant for stiff micro-filaments, such as microtubules.Comment: three figures. To appear in Phys Rev Let

Blood rheology, cardiovascular risk factors, and cardiovascular disease: The West of Scotland Coronary Prevention Study

The West of Scotland Coronary Prevention Study (WOSCOPS) showed that pravastatin reduced the risk of coronary heart disease (CHD) events in 6,595 middle-aged hypercholesterolaemic men aged 45-64 years without prior myocardial infarction followed for an average of 4.9 years. We hypothesised prospectively (a) that baseline levels of haemorheological variables were related to baseline and incident CHD and to mortality; and (b) that reduction in lipoproteins by pravastatin would lower plasma and blood viscosity, a potential contributory mechanism to CHD events. We therefore studied plasma and blood viscosity, fibrinogen, haematocrit, and blood cell counts at baseline and 1 year. At baseline, plasma and blood viscosity were related to risk factors, CHD measures, and claudication. On univariate analysis, baseline levels of all rheological variables (except platelet count) were related to incident CHD; CHD mortality; and total mortality. On multivariate analysis including baseline CHD and risk factors, plasma and blood viscosity, haematocrit and white cell count each remained significantly associated with incident CHD; while fibrinogen remained an independent predictor of mortality (all p<0.03). After one year, lipoprotein reduction by pravastatin was associated with significant reductions (about one quarter of a standard deviation) in plasma viscosity (mean difference 0.02 mPa.s, p<0.001) and in blood viscosity (mean difference 0.06 mPa.s, p<0.001), but was not associated with significant changes in other rheological variables. We therefore suggest that pravastatin therapy, which reduces elevated lipoproteins in hypercholesterolaemic men, may lower risks of CHD and mortality partly by lowering plasma and blood viscosity. Further studies are required to test this hypothesis

Stratigraphy and chronology of the Stent tephra, a c. 4000 year old distal silicic tephra from Taupo Volcanic Centre, New Zealand.

Tephrostratigraphic and chronologic studies in two areas of the North Island have identified a previously unrecorded, thin, distal silicic tephra derived from the Taupo Volcanic Centre. In Taranaki, three radiocarbon ages of the uncorrelated tephra are consistent with the independent radiocarbon chronology obtained from enveloping Egmontsourced tephras. In western Bay of Plenty, where the uncorrelated tephra is also directly dated, it is overlain by Whakaipo Tephra (c. 2.7 ka) and underlain by Hinemaiaia Tephra (c. 4.5 ka). From these sites in Taranaki and western Bay of Plenty, seven radiocarbon dates obtained on the uncorrelated silicic tephra yield an error-weighted mean age of 3970 ±31 conventional radiocarbon years B.P. The ages on the uncorrelated tephra (informally referred to as Stent tephra) from both areas are statistically identical but significantly different from those on both Waimihia and Hinemaiaia Tephras. occurrence of Stent tephra in Taranaki, c. 160 km upwind from the postulated source area, and in western Bay of Plenty, suggests that it represents the product of a moderately large plinian eruption. Until recently, its validity as a discrete eruptive event had been problematical, because a near-source equivalent deposit between Waimihia and Hinemaiaia Tephras was not recognised in the Taupo area. However, a revised stratigraphy proposed by C. J. N. Wilson in 1993 for eastern sectors of the Taupo area shows that multiple tephra layers were erupted from Taupo volcano between c. 3.9 and 5.2 ka. Of these newly recognised layers, unit-g--the product of a moderately large eruption (>0.15 km3) at c. 4.0 ka--is tentatively correlated with Stent tephra. Other eruptive units recognised by Wilson are either too old or too small in volume to be considered as likely correlatives

Metabolic Cost of Supported Treadmill Running

Please view abstract in the attached PDF fil

Uncertainty in the sensitivity of Arctic sea ice to global warming in a perturbed parameter climate model ensemble

The retreat of Arctic sea ice is a very likely consequence of climate change and part of a key feedback process, which can accelerate global warming. The uncertainty in predictions in the rate of sea ice retreat requires quantification and ultimately reduction via observational constraints. Here we analyse a climate model ensemble with perturbations to parameters in the atmosphere model. We find a large range of the sensitivity of Arctic sea-ice retreat to global temperature change, from 11 to 18% per degrees C. This is placed in the context of the uncertainty obtained by alternative model ensembles. Reasons for the different sensitivities are explored and we find that differences in the amount of ocean and atmospheric heat transported from low to high latitudes dominates over local radiative contributions to the heat budget. Furthermore, we find no significant relationship between the uncertainty in sea ice response to climate change and climate sensitivity

Genome-wide association study of behavioural and psychiatric features in human prion disease.

Prion diseases are rare neurodegenerative conditions causing highly variable clinical syndromes, which often include prominent neuropsychiatric symptoms. We have recently carried out a clinical study of behavioural and psychiatric symptoms in a large prospective cohort of patients with prion disease in the United Kingdom, allowing us to operationalise specific behavioural/psychiatric phenotypes as traits in human prion disease. Here, we report exploratory genome-wide association analysis on 170 of these patients and 5200 UK controls, looking for single-nucleotide polymorphisms (SNPs) associated with three behavioural/psychiatric phenotypes in the context of prion disease. We also specifically examined a selection of candidate SNPs that have shown genome-wide association with psychiatric conditions in previously published studies, and the codon 129 polymorphism of the prion protein gene, which is known to modify various aspects of the phenotype of prion disease. No SNPs reached genome-wide significance, and there was no evidence of altered burden of known psychiatric risk alleles in relevant prion cases. SNPs showing suggestive evidence of association (P<10(-5)) included several lying near genes previously implicated in association studies of other psychiatric and neurodegenerative diseases. These include ANK3, SORL1 and a region of chromosome 6p containing several genes implicated in schizophrenia and bipolar disorder. We would encourage others to acquire phenotype data in independent cohorts of patients with prion disease as well as other neurodegenerative and neuropsychiatric conditions, to allow meta-analysis that may shed clearer light on the biological basis of these complex disease manifestations, and the diseases themselves