5,061 research outputs found
Computer program developed for flowsheet calculations and process data reduction
Computer program PACER-65, is used for flowsheet calculations and easily adapted to process data reduction. Each unit, vessel, meter, and processing operation in the overall flowsheet is represented by a separate subroutine, which the program calls in the order required to complete an overall flowsheet calculation
Energy efficient engine: Low-pressure turbine subsonic cascade component development and integration program
A subsonic cascade test program was conducted to provide technical data for optimizing the blade and vane airfoil designs for the Energy Efficient Engine Low-Pressure Turbine component. The program consisted of three parts. The first involved an evaluation of the low-chamber inlet guide vane. The second, was an evaluation of two candidate aerodynamic loading philosophies for the fourth blade root section. The third part consisted of an evaluation of three candidate airfoil geometries for the fourth blade mean section. The performance of each candidate airfoil was evaluated in a linear cascade configuration. The overall results of this study indicate that the aft-loaded airfoil designs resulted in lower losses which substantiated Pratt & Whitney Aircraft's design philosophy for the Energy Efficient Engine low-pressure turbine component
Surveying the solar system by measuring angles and times: from the solar density to the gravitational constant
A surprisingly large amount of information on our solar system can be gained
from simple measurements of the apparent angular diameters of the sun and the
moon. This information includes the average density of the sun, the distance
between earth and moon, the radius of the moon, and the gravitational constant.
In this note it is described how these and other quantities can be obtained by
simple earthbound measurements of angles and times only, without using any
explicit information on distances between celestial bodies. The pedagogical and
historical aspects of these results are also discussed briefly.Comment: 12 pges, one figur
Preferential attachment of communities: the same principle, but a higher level
The graph of communities is a network emerging above the level of individual
nodes in the hierarchical organisation of a complex system. In this graph the
nodes correspond to communities (highly interconnected subgraphs, also called
modules or clusters), and the links refer to members shared by two communities.
Our analysis indicates that the development of this modular structure is driven
by preferential attachment, in complete analogy with the growth of the
underlying network of nodes. We study how the links between communities are
born in a growing co-authorship network, and introduce a simple model for the
dynamics of overlapping communities.Comment: 7 pages, 3 figure
Provably Secure Double-Block-Length Hash Functions in a Black-Box Model
In CRYPTO’89, Merkle presented three double-block-length
hash functions based on DES. They are optimally collision resistant in
a black-box model, that is, the time complexity of any collision-finding
algorithm for them is Ω(2^<l/2>) if DES is a random block cipher, where
l is the output length. Their drawback is that their rates are low. In
this article, new double-block-length hash functions with higher rates
are presented which are also optimally collision resistant in the blackbox
model. They are composed of block ciphers whose key length is twice
larger than their block length
Outgassing of icy bodies in the solar system - I. The sublimation of hexagonal water ice through dust layers
Our knowledge about the physical processes determining the activity of comets
were mainly influenced by several extremely successful space missions, the
predictions of theoretical models and the results of laboratory experiments.
However, novel computer models should not be treated in isolation but should be
based on experimental results. Therefore, a new experimental setup was
constructed to investigate the temperature dependent sublimation properties of
hexagonal water ice and the gas diffusion through a dry dust layer covering the
ice surface. We show that this experimental setup is capable to reproduce known
gas production rates of pure hexagonal water ice. The reduction of the gas
production rate due to an additional dust layer on top of the ice surface was
measured and compared to the results of another experimental setup in which the
gas diffusion through dust layers at room temperature was investigated. We
found that the relative permeability of the dust layer is inversely
proportional to its thickness, which is also predicted by theoretical models.
However, the measured absolute weakening of the gas flow was smaller than
predicted by models. This lack of correspondence between model and experiment
may be caused by an ill-determination of the boundary condition in the
theoretical models, which further demonstrates the necessity of laboratory
investigations. Furthermore, the impedance of the dust layer to the ice
evaporation was found to be similar to the impedance at room temperature, which
means that the temperature profile of the dust layer is not influencing the
reduction of the gas production. Finally, we present the results of an extended
investigation of the sublimation coefficient, which is an important factor for
the description of the sublimation rate of water ice and, thus, an important
value for thermophysical modeling of icy bodies in the solar system.Comment: Submitted to Icaru
A fully non-linear optimization approach to acousto-electric tomography
This paper considers the non-linear inverse problem of reconstructing an
electric conductivity distribution from the interior power density in a bounded
domain. Applications include the novel tomographic method known as
acousto-electric tomography, in which the measurement setup in Electrical
Impedance Tomography is modulated by ultrasonic waves thus giving rise to a
method potentially having both high contrast and high resolution. We formulate
the inverse problem as a regularized non-linear optimization problem, show the
existence of a minimizer, and derive optimality conditions. We propose a
non-linear conjugate gradient scheme for finding a minimizer based on the
optimality conditions. All our numerical experiments are done in
two-dimensions. The experiments reveal new insight into the non-linear effects
in the reconstruction. One of the interesting features we observe is that,
depending on the choice of regularization, there is a trade-off between high
resolution and high contrast in the reconstructed images. Our proposed
non-linear optimization framework can be generalized to other hybrid imaging
modalities
Acyl-CoA-binding protein (ACBP) localizes to the endoplasmic reticulum and Golgi in a ligand-dependent manner in mammalian cells
International audienceIn the present study, we microinjected fluorescently labelled liver bovine ACBP (FACI-50), into HeLa and bovine mammary gland epithelial (BMGE) cell lines to characterize the localization and dynamics of ACBP in living cells. Results showed that ACBP targeted to the endoplasmic reticulum (ER) and Golgi in a ligand-binding dependent manner. A variant Y28F/K32A-FACI-50, which is unable to bind acyl-CoA, did no longer show association with ER and became segregated from Golgi, as analysed by intensity correlation calculations. Depletion of fatty acids from cells by addition of fatty acid free BSA (FAFBSA) significantly decreased FACI-50 association with Golgi, while fatty acid overloading increased Golgi-association, strongly supporting that ACBP associates with Golgi in a ligand-dependent manner. Fluorescence recovery after photobleaching (FRAP) showed that the fatty acid induced targeting of FACI-50 to Golgi resulted in a 5-fold reduction in FACI-50 mobility. We suggest that ACBP is targeted to ER and Golgi in a ligand-binding dependent manner in living cells, and propose that ACBP may be involved in vesicular trafficking
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