Quality of Work Life: A Study on Civil Construction Workers

The civil construction sector has experienced ongoing changes due to the economic globalization, new technologies, and competition. It demands a large number of workers that are often recruited outside their original city, far from their families, with low work conditions, and without guarantee of continuity in employment, which may affect their health and performance. This study presents an exploratory and descriptive study with a quantitative approach, conducted by the Job Diagnostic Survey (JDS), with 159 workers in the civil construction sector in Brazil. The objective is to assess the level of satisfaction with work, compare the results of different workers at the workplace, and contribute to the discussion about QWL. It was found that the variable General Satisfaction with Work obtained the most negative general average score among the personal and the professional results, pointing out little satisfaction with their work as a whole, which can be improved through training and increase workers empowerment. This study carried out a survey with the construction worker, subjects who are hardly evaluated in research on working conditions. The JDS questionnaire was an important tool in this evaluation, contributing to understanding the variables that impact on the performance of these workers. In this context, improving the quality of work life (QWL) make it possible to assist managers to help workers’ satisfaction at work

Augmented β-cell function and mass in glucocorticoid-treated rodents are associated with increased islet ir-β /AKT/mTOR and decreased AMPK/ACC and AS160 signaling

FAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOGlucocorticoid (GC) therapies may adversely cause insulin resistance (IR) that lead to a compensatory hyperinsulinemia due to insulin hypersecretion. The increased β-cell function is associated with increased insulin signaling that has the protein kinase B (AKT) substrate with 160 kDa (AS160) as an important downstream AKT effector. In muscle, both insulin and AMP-activated protein kinase (AMPK) signaling phosphorylate and inactivate AS160, which favors the glucose transporter (GLUT)-4 translocation to plasma membrane. Whether AS160 phosphorylation is modulated in islets from GC-treated subjects is unknown. For this, two animal models, Swiss mice and Wistar rats, were treated with dexamethasone (DEX) (1 mg/kg body weight) for 5 consecutive days. DEX treatment induced IR, hyperinsulinemia, and dyslipidemia in both species, but glucose intolerance and hyperglycemia only in rats. DEX treatment caused increased insulin secretion in response to glucose and augmented β-cell mass in both species that were associated with increased islet content and increased phosphorylation of the AS160 protein. Protein AKT phosphorylation, but not AMPK phosphorylation, was found significantly enhanced in islets from DEX-treated animals. We conclude that the augmented β-cell function developed in response to the GC-induced IR involves inhibition of the islet AS160 protein activity.Glucocorticoid (GC) therapies may adversely cause insulin resistance (IR) that lead to a compensatory hyperinsulinemia due to insulin hypersecretion. The increased β-cell function is associated with increased insulin signaling that has the protein kinase2014114FAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOsem informaçãosem informaçã

Spatial distribution of wood volume in brazilian savannas

Here we model and describe the wood volume of Cerrado Sensu Stricto, a highly heterogeneous vegetation type in the Savanna biome, in the state of Minas Gerais, Brazil, integrating forest inventory data with spatial-environmental variables, multivariate regression, and regression kriging. Our study contributes to a better understanding of the factors that affect the spatial distribution of the wood volume of this vegetation type as well as allowing better representation of the spatial heterogeneity of this biome. Wood volume estimates were obtained through regression models using different environmental variables as independent variables. Using the best fitted model, spatial analysis of the residuals was carried out by selecting a semivariogram model for generating an ordinary kriging map, which in turn was used with the fitted regression model in the regression kriging technique. Seasonality of both temperature and precipitation, along with the density of deforestation, explained the variations of wood volume throughout Minas Gerais. The spatial distribution of predicted wood volume of Cerrado Sensu Stricto in Minas Gerais revealed the high variability of this variable (15.32 to 98.38 m3 ha-1) and the decreasing gradient in the southeast-northwest direction914COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPESSem informaçã

Production of bacterial cellulose nanocrystals via enzymatic hydrolysis and evaluation of their coating on alginate particles formed by ionotropic gelation

This study aimed to obtain the bacterial cellulose nanocrystals (CNC) by enzymatic hydrolysis and verify the CNC application as coating material in alginate particles. Therefore, the production of CNC was carried out through two enzymatic hydrolysis methods involving a time period of 48 and 72 h. 0.35 mg of dry mass of cellulose was produced approximately 1.6 × 1011 CNC/mL. The CNC obtained by enzymatic hydrolysis at 72 h (Method II) was applied to cover the alginate particles, obtained by ionotropic gelation. The CNC Zeta potential value was about +15 mV and for alginate particles -26.46 ± 1.48 mV. These results confirmed the application of CNC as coating material for alginate particles. It brings an incremental contribution to the knowledge advancement in the pharmaceutical and food area, allowing the engineering of systems to use a mixed composition of nanobiomaterials to modify the release pattern of drugs, macromolecule, nutrients, stabilizers and target specific drug release.The authors acknowledge financial support from Coordination for Higher Level Graduate Improvements (CAPES/Brazil, Grant Numbers 001), National Council for Scientific and Technological Development (CNPq/Brazil), and the State of São Paulo Research Foundation (FAPESP/Brazil, grant numbers 2019/22,626–5 and 2018/10,508–5).info:eu-repo/semantics/publishedVersio

Tolerância de cultivares de soja aos herbicidas imazaquin, diclosulam e sulfentrazone, aplicados em solo de textura arenosa

With the objective to evaluate the genotypes of soybeans when using the herbicides Imazaquim, diclosulam and sulfentrazone, this research was conducted at “ Fazenda Tres Irmãos “ pertaining to Jatai county, Goias, during the growing season 2000/2001. After planting the genotypes of soybeans in arenaceous soil, containing 17,19% clay, 44 g/kg of organic material and CTC of 12,49 cmol/dm³, the herbicides, imazaquin, diclosulan, and sulfentrazone, were sprayed pre-emergence in the following doses – 140 and 280g. /ha, 35 and 70g/ha, 600 and 1200g/ha, respectively. After 15 and 30 days, after the spraying (DAT) of the herbicides, the plant intoxication of the herbicides was evaluated in the genotypes of soybeans. By random of harvest, the height of the plants and insertion of the first string bean, number of plants and yield were evaluated. The conclusions were: a) The herbicides imazaquin, diclosulam and sulfentrazone caused plant intoxication in the genotypes of soybeans planted in arenaceous texture. Especially when the double, of the recommended dose was used. b) In the doses tested, the herbicides didn’t significantly affect the plant density, nor the height of the insertion of the first string bean in the genotypes of soybeans. c) Sulfentrazone in dose equivalent to 1200g/ha, reduced significantly the height in the genotypes-GOBR 93-1283, EMGOPA-316 and CRIXÁS, compared with the untreated area. Diclosulan, in dose equivalent to 35g/ha caused reduction in height in the genotypes – GOIÂNIA, GOBR 93-122243 RNC and LUZIÂNIA. GOBR 93-122243 RCN, GOIÂNIA, LUZIÂNIA, EMGOPA 316, SANTA CRUZ and CRIXÁS already had their heights affected compared with the untreated area, in a dose equivalent to 70g/ha of diclosulan. Imazaquin, in a dose equivalent to 280g/ha, affected significantly the height in the plants of the sort, CRIXAS. d) Diclosulan in dose equivalent to 70g/ha caused significantly reductions in yield in the genotypes – GOBR93-1283, GOBR93-12243 RCN, EMGOPA-302, SANTA CRUZ and EMGOPA-313. Sulfentrazone, used in a dose equivalent to 1200g/ha, caused a reduction in the productivity in the genotypes – GOBR 93-1283, GOBR 93-122243 RNC, GOIATUBA, LUZIÂNIA, EMGOPA-316, EMGOPA-314, SAMBAÍBA, EMGOPA-302, EMGOPA-313 and CRIXÁS. The genotypes – GOIATUBA, EMGOPA-316 and SANTA CRUZ had already showed reductions in productivity, when using imazaquin in a dose equivalent to 280g/ha; e) The genotypes of soybeans showed different tolerance with the herbicides sulfentrazone, diclosulan and imazaquin, specially when there was used a doublet dose. Com o objetivo de avaliar o comportamento de genótipos de soja aos herbicidas imazaquin, diclosulan e sulfentrazone, foi conduzido um ensaio na Fazenda Três Irmãos, pertencente ao município de Jataí-GO, durante a safra 2000/2001. Após semeados os genótipos de soja em solo de textura arenosa contendo 17,19% de argila; 3,44g/Kg de matéria orgânica e CTC de 12,49cmolc/dm3, foram aplicados em pré-emergência os herbicidas imazaquin, diclosulan e sulfentrazone nas doses equivalentes a 140 e 280g/ha, 35 e 70g/ha, 600 e 1200g/ha, respectivamente. Aos 15 e 30 dias após a aplicação dos tratamentos (DAT), foi avaliada a fitotoxicidade dos herbicidas nos genótipos de soja. Por ocasião da colheita, foram avaliadas a altura de plantas e de inserção da primeira vagem, o estande final e o rendimento. Concluiu-se que: a) Os genótipos EMGOPA 302, GO BR 93-12 2243 RNC, GOIÂNIA, EMGOPA 3l6, LUZIÂNIA, foram os mais sensíveis ao herbicida sulfentrazone; b) Diclosulan 70 g/ha causou sintomas visíveis de fitotoxidez as cultivares SANTA CRUZ, EMGOPA 313 e EMGOPA 316; c) Os genótipos EMGOPA 302, SANTA CRUZ e GOIÂNIA, foram os que apresentaram maiores sensibilidade ao herbicida imazaquim 280 g/ha d) Nas doses testadas, os herbicidas não afetaram significativamente a densidade populacional, nem a altura de inserção da primeira vagem dos genótipos de soja; e) Sulfentrazone na dose equivalente a 1200 g/ha provocou reduções significativas na altura de plantas dos genótipos GOBR 93-1283, EMGOPA 316 e CRIXÁS, em relação à testemunha. GOIÂNIA, GOBR93, 122243 RNC e LUZIÂNIA. Diclosulan, em dose equivalente a 35 g/ha, provocou redução na altura de plantas dos genótipos GOIÂNIA, GOBR 93-122243 RNC e LUZIÂNIA; já GOBR 93- 122243 RCN, GOIÂNIA, LUZIANIA, EMGOPA 316, SANTA CRUZ e CRIXÁS tiveram suas alturas afetadas em relação à testemunha, em dose equivalente a 70 g/ha de diclosulan. Imazaquin, em dose equivalente a 280 g/ha, afetou significativamente a altura de plantas da variedade CRIXÁS; d) Diclosulan em dose equivalente a 70 g/há proporcionou reduções significativas nos rendimentos dos genótipos GOBR93-122243 RCN, EMGOPA 302, SANTA CRUZ e EMGOPA 313. Sulfentrazone, utilizado em dose equivalente a 1200 g/ha causou redução na produtividade dos genótipos GOBR 93-122243 RNC, GOIATUBA, LUZIÂNIA, EMGOPA 316, EMGOPA 314, SAMBAÍBA, EMGOPA 302, EMGOPA 313 e CRIXAS. Já os genótipos GOIATUBA, EMGOPA 316 e SANTA CRUZ apresentaram reduções na produtividade com o uso de imazaquin em dose equivalente a 280 g/ha; e) Os genótipos de soja apresentaram tolerância diferenciada aos herbicidas sulfentrazone, diclosulan e imazaquin, em especial quando foi empregado o dobro da dose

Analytical method validation for in vitro permeation of Calendula officinalis L. gel

The objective of this study was to evaluate preliminary stability, as well as to validate an analytical method for in vitro skin permeation study of a gel containing tincture of Calendula officinalis L., aiming at the implementation and consolidation of methodologies to be used as prototype for future development of herbal medicine in the Brazilian Amazon region. The gel showed a satisfactory result during the assessment of its preliminary stability considering that the formulation remained stable throughout cycles at temperatures of 45 °C and 25 °C. Parameters obtained in the validation of the analytical method presented satisfactory results for specificity, linearity (r > 0.99), precision (intra-day and inter-day) with relative standard deviation values (R.S.D. %) below the required maximum of 5 %. Accuracy and robustness were consistent with both the objectives of the work and recommendations of the existing laws, providing the reliability of the data obtained during the skin permeation study, evidenced by the gel tendency to promote the permeation of flavonoids, expressed in rutin, through models of synthetic and biological membrane. However, it was observed that the gel had a higher permeability ratio through synthetic membrane, due to greater cumulative mass of rutin quantified after permeation.Colegio de Farmacéuticos de la Provincia de Buenos Aire

Energy levels and lysine, calcium and phosphorus adjustments on broiler nutrient digestibility and performance

Abstract Chicken broilers digestibility and performance fed with different ME levels, with and without adjustments of digestible lysine, calcium, and available phosphorus, were evaluated. For digestibility, 210 male Cobb 500 chicken broilers were used and distributed into a 3x2+1 factorial arrangement, with three ME levels (3050; 3125 and 3200 kcal/kg) with and without nutrient adjustment, plus one control treatment (2975 kcal ME/kg), totaling seven treatments including six repetitions with five birds into each repetition. For initial performance, 1120 birds were distributed randomly with eight replications within treatments and 20 birds for each replication. For final performance, 1008 chickens were distributed with eight replications and 18 birds for each replication. The DCDM and DCCP were improved (P0.05) between energy and nutrient adjustment, but the increase in energy levels improved the feed conversion ratio (FCR=1.370). Increasing energy density with nutrient adjustment improves both nutrient utilization and bird performance

Effect of postemergence herbicides on agronomics characteristics of soybean cv. Emgopa 316

Conduziu-se um ensaio na fazenda Bela Vista, município de Serranópolis-GO, objetivando avaliar os efeitos de latifolicidas aplicados em pós-emergência, sobre algumas características agronômicas da soja cv. Emgopa 316, com ciclo de maturação precoce. Os tratamentos testados foram: lactofen (168 g/ha), chlorimuron-ethyl (15 g/ha) + óleo mineral (0,2 v/v), fomesafen (250 g/ha) + óleo mineral (0,2 v/v), imazethapyr (100 g/ha) + óleo mineral (0,2% v/v), chlorimuronethyl+ lactofen (12,5+96 g/ha), chlorimuron-ethyl+fomesafen (12,5+ 150 g/ha), chlorirnuron-ethyl+imazethapyr (12,5+50 g/ha), imazethapyr+lactofen (50+96 g/ha), imazethapyr+fomesafen (50+ 150 g/ha), além da testemunha. Os herbicidas, nas doses estudadas, provocaram injúrias às plantas de soja cv. Emgopa 316, com maior intensidade nos tratamentos contendo lactofen, porém não intluenciaram na altura das plantas aos 15,30 e 45 DAT e na colheita da soja. Também não afetaram a altura de inserção da primeira vagem, densidade de plantas, número de vagens/planta, peso de 1000 sementes e nem o rendimento de grãos. A mistura imazethapyr+fomesafen (50+ 150 g/ha) proporcionou o maior número de entrenós, porém, não diferiu estatisticamente dos demais tratamentos, exceto para lactofen (168 g/ha), que proporcionou o menor número de entrenós. O herbicida lactofen isolado ou em combinação com chlorimuron-ethyl ou com imazethapyr, pode se utilizado em soja cv. Emgopa 316, com ciclo de maturação precoce, apresentando resultados semelhantes ao fomesafen isolado ou em mistura com chlorimuron-ethyl ou imazethapyr.  A experiment was carried out at the Bela Vista Farm, in Serranópolis, State ofGoiás, with the objective to evaluate the effects of postemergence herbicides on agronomic characteristcs of soybean cv. Emgopa 316, with premature maturation cycle. Treatments consisted oflactofen (168 glha), chlorimuron-ethyl (15 glha) + mineral oil (0.2 v/v), fomesafen (250 g/ha) + mineral oil (0.2 v/v), imazethapyr (100 g/ha), chlorimuron-ethyl+lactofen (12.5+96 g/ha), chlorimuronethyl+ fomesafen (12.5+ 150 g/ha), chlorirnuron-ethyl+imazethapyr (12.5+50 g/ha), imazethapyr+lactofen (50+96 g/ha), imazethapyr+fomesafen (50+ 150 g/ha), and a handweeded control. The studied herbicide doses caused some injury to soybean, with more intensity in the treatments with lactofen. However, they did not significantly intluence the height of plants at 15, 30 and 45 days after treatments and at soybean harvest. The herbicides also did not significantly affect insertion height of the first pod, final stand, number of podslplant, weight of 1000 seeds and grain production. Imazethapyr+fomesafen (50+ 150 g/ha) gave the best result in number of internodes, but it did not differ statistically from the other treatments, except for lactofen (168 g/ha), that proportioned the lowest number of internodes. Lactofen isolated or combined with chlorimuron-ethyl or with imazethapyr can be used in soybean cv. Emgopa 316, showing results similar to fomesafen isolated or in mixture with chlorimuron-ethyl or imazethapyr