10 research outputs found
Treatment characteristics and outcomes of pure Acinar cell carcinoma of the pancreas - A multicentric European study on radically resected patients
- Author
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Background: Acinar cell carcinomas (ACC) belong to the exocrine pancreatic malignancies. Due to their rarity, there is no consensus regarding treatment strategies for resectable ACC. Methods: This is a retrospective multicentric study of radically resected pure pancreatic ACC. Primary endpoints were overall survival (OS) and disease-free survival (DFS). Further endpoints were oncologic outcomes related to tumor stage and therapeutic protocols. Results: 59 patients (44 men) with a median age of 64 years were included. The median tumor size was 45.0 mm. 61.0% were pT3 (n = 36), nodal positivity rate was 37.3% (n = 22), and synchronous distant metastases were present in 10.1% of the patients (n = 6). 5-Years OS was 60.9% and median DFS 30 months. 24 out of 31 recurred systemically (n = 18 only systemic, n = 6 local and systemic). Regarding TNM-staging, only the N2-stage negatively influenced OS and DFS (p = 0.004, p = 0.001). Adjuvant treatment protocols (performed in 62.7%) did neither improve OS (p = 0.542) nor DFS (p = 0.159). In 9 cases, radical resection was achieved following neoadjuvant therapy. Discussion: Radical surgery is currently the mainstay for resectable ACC, even for limited metastatic disease. Novel (neo)adjuvant treatment strategies are needed, since current systemic therapies do not result in a clear survival benefit in the perioperative setting
Health timeline: an insight-based study of a timeline visualization of clinical data
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
BMI, physical inactivity, cigarette and alcohol consumption in female nursing students: a 5-year comparison
- Author
- AN Schmelz
- AS Holloway
- B Kolleck
- Bundeszentrale für gesundheitliche Aufklärung
- C Purcell
- CW Warren
- E Frank
- E Frank
- Franziska Lehmann
- H Seitz
- J Klewer
- Joachim Kugler
- Jörg Klewer
- K Abu-Omar
- K Voigt
- K von Lindeman
- K von Lindeman
- Katharina von Lindeman
- L Strobel
- M Adams
- Max Rubner-Institut
- P Neumann
- PGU Panel
- PH Lee
- R Rosenbrock
- S Connor Gorber
- S Kohler
- S Krug
- S Neubauer
- S Winkler
- SL Wong
- SS Lim
- T Lampert
- U Hapke
- WHO
- WHO
- WHO
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Alanine-glyoxylate aminotransferase 2 (AGXT2) Polymorphisms Have Considerable Impact on Methylarginine and β-aminoisobutyrate Metabolism in Healthy Volunteers
- Author
- A Kittel
- A Meinitzer
- AJ Cardounel
- Ana Kralj
- Anja Kittel
- B Caplin
- B Siegerink
- BS Blumberg
- C Schmidt
- D Atzler
- E Schepers
- E Schwedhelm
- E Schwedhelm
- EP Rhee
- F Schulze
- Fabian Müller
- G Nicholson
- Heinrich Sticht
- HR Crumpler
- J De Grouchy
- J Jacobi
- J Leiper
- J Strobel
- JT Kielstein
- Jörg König
- K Suhre
- M Kleber
- Maren Mieth
- Markus R. Heinrich
- Martin F. Fromm
- N Guex
- N Lüneburg
- Oliver Zolk
- P Vallance
- R Maas
- R Sanchez
- R Schnabel
- RA Sayle
- Renke Maas
- RH Böger
- RN Rodionov
- RW Hooft
- S Wang
- T Ogawa
- Takeo Yoshikawa
- VN Malashkevich
- Y Kontani
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
Encoded self-assembling chemical libraries
- Author
- A Carotti
- A Fersht
- A Scozzafava
- AD Griffiths
- B Cuenoud
- Christoph E Dumelin
- D Neri
- DA Erlanson
- Dario Neri
- DE Epps
- DJ Maly
- G Kohler
- G Winter
- GT Hermanson
- GT Morgan
- HS Rye
- J McCafferty
- J Scheuermann
- JB Doyon
- Jörg Scheuermann
- L Gold
- M Pellecchia
- O Ramstrom
- PJ Hajduk
- R Fattorusso
- RE Hawkins
- S Brenner
- S Josephson
- S Otto
- SA Strobel
- Samu Melkko
- SB Shuker
- SL Schreiber
- T Clackson
- TR Gadek
- VE Velculescu
- WP Jencks
- Y Pocker
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
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- 'Vandenhoeck & Ruprecht GmbH & Co, KG'
- Publication date
- Field of study
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- Publication venue
- 'Vandenhoeck & Ruprecht GmbH & Co, KG'
- Publication date
- Field of study
Anhang
- Author
- Ackeren
- Aichele Alexander
- Albert Karl
- Alt Karin
- Aristophanes Ecclesiazusae
- Aristophanes Sämtliche Komödien
- Aristoteles
- Aristoteles Metaphysik
- Aristoteles Nikomachische Ethik
- Aristoteles Poetik
- Aristotelis Ethica Nicomachea
- Aristotelis Metaphysica
- Aristotle
- Baltes Matthias
- Benz Hubert
- Bernadete Seth
- Blößner Norbert
- Blößner Norbert
- Bordt Michael
- Bourriot FØlix
- Brickhouse Thomas C
- Brisson Luc
- Brisson Luc
- Bruit Zaidman
- Burkert Walter
- Burnyeat Myles F
- Burnyeat Myles F
- Calvo
- Carone Gabriela Roxana
- Cherubin Rose
- Christiansen Michel
- Chvatík Ivan
- Clay Diskin
- Contrasting Arguments
- Cürsgen Dirk
- Cürsgen Dirk
- Dalfen Joachim
- de Sophisticis Elenchis
- Dilthey Wilhelm
- Diogenes Laertius
- Dissoi Logoi Zweierlei Ansichten
- Dixsaut Monique
- Dixsaut Monique
- Dixsaut Monique
- Döring
- Dörrie
- Enders Markus
- Epicrates
- Erler
- Erler Michael
- Ferber Rafael
- Figal Günter
- Figal Günter
- Flashar Hellmut
- Fowler Harold N
- Fragmente der Griechischen Historiker I.
- Fragmente der Vorsokratiker
- Frede Dorothea
- Frede Michael
- Frede Michael
- Frede Michael
- Gadamer Hans-Georg
- Gadamer Hans-Georg
- Geiger Rolf
- Gerson Lloyd P
- Gigon Olof
- Gorgias von Leontinoi Reden
- Gotshalk Richard
- Graeser Andreas
- Graeser Andreas
- Guthrie William K.C
- Hadot Ilsetraut
- Hadot Pierre
- Hadot Pierre
- Hadot Pierre
- Hardy Jörg
- Hardy Jörg
- Havlíček
- Havlíček
- Havlíček Aleš
- Hawtrey R. S. W.
- Heitsch Ernst
- Heitsch Ernst
- Heitsch Ernst
- Heitsch Ernst
- Heitsch Ernst
- Heitsch Ernst
- Heitsch Ernst
- Herodoros
- Herodot
- Hinske Norbert
- Hippocrate
- Hippocrates et Corp
- Homer Illias
- Homer Odyssee
- Homeri Ilias
- Homeri Odyssea P.
- Horn
- Horn Christoph
- Horn Christoph
- Huss Bernhard
- Hölscher
- Isocrate Discours
- Isocrates
- Isokrates Sämtliche Werke
- Jacoby F.
- Jaeger Werner
- Janka
- Johansen Thomas
- Kahn Charles H
- Kamlah Wilhelm
- Kerferd George B
- Kobusch Theo
- Kobusch Theo
- Kobusch Theo
- Kobusch Theo
- Kobusch Theo
- Kobusch Theo
- Kobusch Theo
- Kobusch Theo
- Kobusch Theo Mojsisch
- Kranz Margarita
- Kranz Margarita
- Krämer Hans
- Lampert
- Lesher J. H.
- Lysias
- Lysias Reden
- Manuwald Bernd
- Manuwald Bernd
- Manuwald Bernd
- Mariß Ruth
- Matthews Gareth B
- Mesch Walter
- Meyer-Abich Klaus Michael
- Mojsisch Burkhard
- Moravcsik J. M. E.
- Morrison Donald
- Männlein-Robert Irmgard
- Männlein-Robert Irmgard
- Müller Carl Werner
- Müller Gerhard
- Müller Gerhard
- Müller Gerhard
- Nails Debra
- Natali Carlo
- Neschke-Hentschke Ada
- Nestle Wilhelm
- Niehues-Pröbsting Heinrich
- Nilsson Martin P
- Notomi
- Oeing-Hanhoff Ludger
- Oeing-Hanhoff Ludger
- Osborne Catherine
- Parmenides
- Patzer Harald
- Penner
- Pieper Joseph
- Piras Claudia
- Plato
- Plato Gorgias
- Plato Gorgias
- Plato Phaedo
- Plato Symposion
- Plato Symposium
- Plato Theaetetus
- Plato's Phaedo
- Plato's Sophist
- Platon
- Platon Der Staat
- Platon Gorgias
- Platon Gorgias
- Platon Kritias
- Platon Le Banquet
- Platon Lysis
- Platon Phaidon
- Platon Phaidon
- Platon Philebos
- Platon Politikos
- Platon Protagoras
- Platon Socrate
- Platon Sokrates
- Platon Sophistes
- Platon Symposion
- Platonis Opera
- Platonis Rempublicam
- Platons Menexenos Einleitung
- Reeve C.D.C.
- Rehn Rudolf
- Rosen Stanley
- Rowe Christopher
- Rowe Christopher
- Rowe Christopher
- Rowe Christopher
- Schaeffler Richard
- Schefer Christina
- Schmidt Jochen
- Schulz Peter
- Schwartz Maria
- Schäfer Christian
- Schäfer Christian
- Schäfer Christian
- Scolnicov Samuel
- Sedley David
- Sier Kurt
- Slaveva-Griffin Svetla
- Snell Bruno
- Strobel Benedikt
- Strycker E.
- Stückelberger Alfred
- Summerell Orrin F
- Szaif Jan
- Szlezµk Thomas Alexander
- Szlezµk Thomas Alexander
- Szlezµk Thomas Alexander
- Szlezµk Thomas Alexander
- Szlezµk Thomas Alexander
- Szlezµk Thomas Alexander
- Sˇpinka Sˇtpµn
- Tejera Victorino
- Tejera Victorino
- Thesleff Holger
- Thesleff Holger
- Thurner Martin
- Usener Sylvia
- Valk Manuscripts
- Vgl
- Vlastos Gregory
- Vlastos Gregory
- Vol I. Haiim B.
- Volkmann-Schluck Karl-Heinz
- Vries G. J.
- Vries G. J.
- Weiss Roslyn
- Welwei Karl-Wilhelm
- Wieland Wolfgang
- Witte Bernd
- Wittern Renate
- Wohlgenannt Rudolf
- Wurm Achim
- Xenophon
- Xenophon Anabasis
- Xenophon Das Gastmahl
- Xenophon Oeconomicus
- Zehnpfennig Barbara
- Zuckert Catherine H
- Zuckert Catherine H
- Publication venue
- 'Vandenhoeck & Ruprecht GmbH & Co, KG'
- Publication date
- Field of study
7. Literatur
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- Fritz Volkmar
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- Garci´a-Treto Francisco Oscar
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- Honigmann Ernst
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- Katzenstein H.
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- King Geoffrey R.D. u. a.
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- Klein Samuel
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- Kloner Stern
- Klostermann Erich
- Knauf
- Knauf Ernst
- Knauf Ernst
- Knauf Ernst Axel
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- Riemschneider Margarete
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- Schart Krispenz
- Schatz Werner
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- Schipper Friedrich
- Schmid Riedweg
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- Stefanovic Zdravko
- Stern Menahem
- Sternberg Georg
- Steuernagel Carl
- Stoebe Hans-Joachim
- Stoebe Hans-Joachim
- Stolz Fritz
- Stordalen Terje
- Stordalen Terje
- Streck Michael P
- Strobel August
- Strobel August
- Stronach David
- Stronach David
- Stucky Rolf
- Svensson Jan
- Sweeney Marvin A
- Sæbø Magne
- Talmon Shemaryahu
- Tanner Hans Andreas
- Taylor Joan E
- Thareani Yifat
- Thiel Winfried
- Thompson Henry O
- Thompson Henry O
- Thompson Henry O
- Thompson Henry O
- Thompson John Alexander
- Thompson Thomas L
- Thomsen Peter
- Timm Stefan
- Timm Stefan
- Timm Stefan
- Timm Stefan
- Toews Wesley I
- Toombs Lawrence E
- Toombs Lawrence E
- Trumbull H. Clay
- Török Lµszló
- Uehlinger Christoph
- Uehlinger Christoph
- Ulrich Eugene
- Unger Eckard
- Ussishkin Cooley
- Ussishkin David
- Ussishkin David
- Vallat FranÅois
- Vallat FranÅois
- Vallat FranÅois
- Van der Mieroop Marc
- Van Seters John
- Vaux
- Vaux
- Vaux
- Vaux
- Vaux
- Vaux
- Vieweger Dieter
- Vincent Abel
- Vincent Louis-Hugues
- Vincent Mackay
- Vogt Ernst
- Vos Jacobus
- Vrolijk Paul D
- Wacker Marie-Theres
- Wagner Jörg
- Wagner Rademacher
- Waldmann Helmut
- Waldmann Helmut
- Waldmann Rademacher
- Wallace Howard N
- Wallis Gerhard
- Wallis Gerhard
- Wallis Gerhard
- Ward William A
- Watzinger Wulzinger
- Wayne Ferris Paul
- Weber
- Weigl Michael
- Weippert Helga
- Weippert Manfred
- Weippert Manfred
- Weippert Manfred
- Weippert Manfred
- Weippert Manfred
- Weippert Manfred
- Weippert Manfred
- Weitzman Steven
- Weißbach Franz Heinrich
- Welten Peter
- Welten Peter
- Wenham Gordon J
- Wenning Zenger
- Wente Edward F
- Westenholz Joan Goodnick
- Westenholz Joan Goodnick
- Westenholz Joan Goodnick
- Whitehouse Helen
- Wilhelm Gernot
- Willeitner Joachim
- Williams David Salter
- Wilson Kevin A
- Wimmer Stefan Jakob
- Wiseman Donald John
- Witte Markus
- Witte Markus
- Wolff Hans Walter
- Wolters Albert M
- Wood Bryant G
- Wood Bryant G
- Wood Bryant G
- Woolley
- Woolley Charles
- Woolley Charles Leonard
- Woolley Charles Leonard
- Worschech Udo
- Wright G. Ernest
- Wright George R.H.
- Wright George R.H.
- Wächter Ludwig
- Würthwein Ernst
- Wüst Manfried
- Wüst Manfried
- Yeivin Zeev
- Yisraeli Yael
- Younker Randall W
- Yule Paul
- Zadok Ran
- Zadok Ran
- Zakovitch Yair
- Zertal Adam
- Zertal Adam
- Zettler Richard L
- Ziemer Benjamin
- Ziemer Benjamin
- Zilberbod Irina
- Zimmerli Walther
- Zucconi Laura Marie
- Zwickel Wolfgang
- Zwickel Wolfgang
- Zwickel Wolfgang
- Zwickel Wolfgang
- Zwickel Wolfgang
- Zwickel Wolfgang
- Zwickel Wolfgang
- Publication venue
- 'Vandenhoeck & Ruprecht GmbH & Co, KG'
- Publication date
- Field of study