Combined collision-induced dissociation and photo-selected reaction monitoring mass spectrometry modes for simultaneous analysis of coagulation factors and estrogens

AbstractOral estrogens are directly associated with changes in plasma levels of coagulation proteins. Thus, the detection of any variation in protein concentrations due to estrogen contraceptives, by a simultaneous analysis of both coagulation proteins and estrogens, would be a very informative tool. In the present study, the merit of photo-selected reaction monitoring (SRM), a new analytical tool, was evaluated towards estrogens detection in plasma. Then, SRM and photo-SRM detection modes were combined for the simultaneous analysis of estrogen molecules together with heparin co-factor and factor XIIa, two proteins involved in the coagulation cascade. This study shows that photo-SRM could open new multiplexed analytical routes

Innovation across cultures: Connecting leadership, identification, and creative behavior in organizations

Innovation is considered essential for today's organizations to survive and thrive. Researchers have also stressed the importance of leadership as a driver of followers' innovative work behavior (FIB). Yet, despite a large amount of research, three areas remain understudied: (a) The relative importance of different forms of leadership for FIB; (b) the mechanisms through which leadership impacts FIB; and (c) the degree to which relationships between leadership and FIB are generalizable across cultures. To address these lacunae, we propose an integrated model connecting four types of positive leadership behaviors, two types of identification (as mediating variables), and FIB. We tested our model in a global data set comprising responses of N = 7,225 participants from 23 countries, grouped into nine cultural clusters. Our results indicate that perceived LMX quality was the strongest relative predictor of FIB. Furthermore, the relationships between both perceived LMX quality and identity leadership with FIB were mediated by social identification. The indirect effect of LMX on FIB via social identification was stable across clusters, whereas the indirect effects of the other forms of leadership on FIB via social identification were stronger in countries high versus low on collectivism. Power distance did not influence the relations

Political leaders' identity leadership and civic citizenship behavior:The mediating role of trust in fellow citizens and the moderating role of economic inequality

Identity leadership captures leaders efforts to create and promote a sense of shared group membership (i.e., a sense of “we” and of “us”) among followers. The present research report tests this claim by drawing on data from 26 countries that are part of the Global Identity Leadership Development (GILD) project to examine the relationship between political leaders' identity leadership and civic citizenship behavior (N = 6787). It also examines the contributions of trust and economic inequality to this relationship. Political leaders' identity leadership (PLIL) was positively associated with respondents' people-oriented civic citizenship behaviors (CCB-P) in 20 of 26 countries and civic citizenship behaviors aimed at one's country (CCB-C) in 23 of 26 countries. Mediational analyses also confirmed the indirect effects of PLIL via trust in fellow citizens on both CCB-P (in 25 out of 26 countries) and CCB-C (in all 26 countries). Economic inequality moderated these effects such that the main and indirect effects of trust in one's fellow citizens on CCB-C were stronger in countries with higher economic inequality. This interaction effect was not observed for CCB-P. The study highlights the importance of identity leadership and trust in fellow citizens in promoting civic citizenship behavior, especially in the context of economic inequality.</p

How is the economic crisis socially assessed?

Based on the Social Representation Theory, the purpose of this article is to explore how lay-people consider both the economic crisis and risk, and to link these social representations to behavior. The article offers an original approach with the articulation of two studies about the social construction of risk and crises. It also contributes to the development of research methods for studying the connections between representations and practical implications. Based on this, the impact of the social representation of the crisis on the perceived ability to act is approached. The first study focuses on free-association tasks, with two distinct target terms: ‘risk’ and ‘crisis’. The structural approach, with a prototypical analysis, allowed the identification of two different representations: (1) for risk, ‘danger’ is the central element; (2) for crisis, ‘economy’ and ‘money’ constitute the main components of the representation. The second study investigates the links between the two previously detected structures and their relations with the perceived ability to act in a financial crisis context. Some aspects of social knowledge were found to have an impact on perceived ability to act

Gambling games : risk-taking, social representation and disorder

Les prises de décision ainsi que l'addiction sont influencées par une combinaison de trois types de facteurs: la situation, l'objet et les différences individuelles (Appelt, Milch, Handgraaf, & Weber, 2011; Bonnaire, 2009; Einhorn, 1970; Griffiths, 2003). Chacun de ces facteurs correspond à un chapitre de cette thèse. Dans le Chapitre 1, l'influence de la situation est examinée à travers l'influence du Contexte Social. L'influence du Contexte Social est étudiée à travers la Simple Présence d'une Audience ainsi qu'avec la présence d'un Climat de Compétition. Dans le Chapitre 2, l'influence de l'objet est examinée à travers l'effet de la connaissance de l'objet : les comportements de prise de risque sont étudiés quand les participants sont confrontés à un jeu qu'ils connaissent et quand ils sont confrontés à un jeu qu'ils ne connaissent pas. Dans le Chapitre 3, l'influence de différences individuelles est examinée à travers l'effet de l'estime de soi sur la prise de risque. Deux mesures d'estime de soi sont utilisées : la première est une mesure générale d'Estime de Soi alors que la seconde est une mesure composée de deux dimensions : la dimension Valeur et la dimension Compétence. La théorie des Représentations sociales sous-tend qu'il y a une relation entre les Représentations Sociales et les comportements. Le Chapitre 4 examine la Représentation Sociale du risque dans un contexte de jeu à l'aide de deux études. La première étude est réalisée via la procédure de l'association libre et la seconde étude est composée d'entretiens auprès de joueurs sains et de joueurs pathologiques.Decision-making, as well as addiction, are influence by a combination of three sets of factors: the situation, the object and individual differences (Appelt, Milch, Handgraaf, & Weber, 2011; Bonnaire, 2009; Einhorn, 1970; Griffiths, 2003). Each of these factors corresponds to a chapter of this thesis. In Chapter 1, the influence of the situation is investigated through the effect of Social Context. The influence of the Social Context is studied through, the Mere Presence of an Audience and through the presence of a Competitive Climate. In Chapter 2, the influence of the object is investigated through the effect of the knowledge of the object: risk-taking behavior is studied when participants are confronted to a known game and when they are confronted to an unknown game. In Chapter 3, the influence of individual differences is investigated through the effect of Self-Esteem on risk-taking behaviors. Two measures of Self-Esteem are used: the first one is a general measure of Self-Esteem while the second one is composed of two dimensions distinguishing Self-Liking and Self-Competence. The Social Representation Theory describes a relation between Social Representation and behavior. In this line, Chapter 4 investigates the Social Representation of risk in a gambling context with two studies. The first study is done via free association tasks and the second study is based on interviews with both gamblers who have gambling disorders and gamblers who do not have gambling disorder

Unity, Diversity and Culture

A peer-reviewed book based on presentations at the XXII Congress of the International Association for Cross-Cultural Psychology, 2014, Reims, France. (c) 2016, International Association for Cross-Cultural Psychology (ebook)https://scholarworks.gvsu.edu/iaccp_proceedings/1006/thumbnail.jp

Identity Leadership Going Global: Validation of the Identity Leadership Inventory (ILI) across 20 Countries.

English-speakers sometimes say that they feel “moved to tears,” “emotionally touched,” “stirred,” or that something “warmed their heart;” other languages use similar passive contact metaphors to refer to an affective state. The authors propose and measure the concept of kama muta to understand experiences often given these and other labels. Do the same experiences evoke the same kama muta emotion across nations and languages? They conducted studies in 19 different countries, 5 continents, 15 languages, with a total of 3,542 participants. They tested the construct while validating a comprehensive scale to measure the appraisals, valence, bodily sensations, motivation, and lexical labels posited to characterize kama muta. The results are congruent with theory and previous findings showing that kama muta is a distinct positive social relational emotion that is evoked by experiencing or observing a sudden intensification of communal sharing. It is commonly accompanied by a warm feeling in the chest, moist eyes or tears, chills or piloerection, feeling choked up or having a lump in the throat, buoyancy, and exhilaration. It motivates affective devotion and moral commitment to communal sharing. Although the authors observed some variations across cultures, these 5 facets of kama muta are highly correlated in every sample, supporting the validity of the construct and the measure.College of Graduate Studie

Self-Objectification and its Biological, Psychological and Social Predictors: A Cross-Cultural Study in Four European Countries and Iran

Although scholars started investigating self-objectification more than twenty years ago, only a few studies focused on men and even fewer have taken into account the cross-cultural dimension. Our study focused on the antecedents of self-objectification paying attention to the role of biological and sociodemographic variables (gender, BMI), psychological characteristics (self-esteem, perfectionism) together with social and cultural factors (internalization of media standards, influence of family and friends). Self-objectification was operationalized as Body Shame and Body Surveillance. A self-reported questionnaire was administered to 2165 adults living in four European countries (UK, Italy, Poland and Romania) and Iran. Ten regression models were performed (2 per country) to analyse the correlates of self-objectification. Overall, self-objectification emerged as a process affected by factors entrenched in psychological, biological, social and cultural domains, partially different for Body Shame and Body Surveillance. Findings showed the key role of self-esteem as a protective factor against Body Shame across countries. On the other hand, the internalization of media standards emerged as risk factor for both Body Shame and Body Surveillance in the five countries. Taken together, these results underline the complexity of self-objectification and the need to deepen research on this topic among non-Western countries