A prototype and demonstrator of Akogrimo’s architecture: An approach of merging grids, SOA, and the mobile Internet

The trend of merging telecommunication infrastructures with traditional Information Technology (IT) infrastructures is ongoing and important for commercial service providers. The driver behind this development is, on one hand, the strong need for enhanced services and on the other hand, the need of telecommunication operators aiming at value-added service provisioning to a wide variety of customers. In the telecommunications sector, the IP Multimedia Subsystem (IMS) is a promising service platform, which may become a ''standard'' for supporting added-value services on top of the next generation network infrastructure. However, since its range of applicability is bound to SIP- enabled services, IMS extensions are being proposed by ''SIPifying'' applications. In parallel to these developments within the traditional IT sector, the notion of Virtual Organizations (VO) enabling collaborative businesses across organizational boundaries is addressed in the framework of Web Services (WS) standards implementing a Service-oriented Architecture (SOA). Here, concepts for controlled resource and service sharing based on WS and Semantic Technologies have been consolidated. Since the telecommunications sector has become, in the meantime ''mobile'', all concepts brought into this infrastructure must cope with the dynamics mobility brings in. Therefore, within the Akogrimo project the VO concept has been extended towards a Mobile Dynamic Virtual Organization (MDVO) concept, additionally considering key requirements of mobile users and resources. Especial attention is given to ensure the duality of the merge of both, SOA and IMS approaches to holistically support SOA-enabled mobile added-value services and their users. This work describes major results of the Akogrimo project, paying special attention to the overall Akogrimo architecture, the prototype implemented, and the key scenario in which the instantiated Akogrimo architecture shows a very clear picture of applicability, use, and an additional functional evaluation

Intravascular Large B-Cell Lymphoma Presenting as Dementia and Hemolytic Anemia

Background: Intravascular lymphoma (IVL) is an uncommon disease characterized by atypical lymphoid cells growing inside the lumina of small vessels. The diversity of clinical presentation due to possible involvement of multiple organs often complicates its diagnosis. Case Report: Here, we report on a case of IVL with rapidly progressive dementia and Coombs-negative hemolytic anemia. Interestingly, the erythrocytes exhibited a decreased osmotic resistance. Bone marrow histopathology revealed increased erythropoiesis and, finally, a small monoclonal B lymphocyte population. Cerebral magnetic resonance imaging (MRI) demonstrated few micro-bleedings. Computed tomography (CT) showed bilateral ground-glass opacity of the lungs. Within a few days, the patient developed respiratory failure and died. On post-mortem examination, intravascular large B-cell lymphoma with almost complete infiltration of the brain and lungs was diagnosed. Conclusion: IVL should be considered early in situations of unexplained neuropsychiatric disease along with markedly elevated levels of lactic dehydrogenase, anemia, and hemolysis

New anode- and cathode-active materials for organic batteries

The development and synthesis of new polymers for organic batteries is a long and difficult process rife with challenges. However, the reward for this are suitable materials for the next generation of secondary batteries. The investigations within the scope of this thesis are focused on the discovery of new redox-active polymers suitable as active materials in batteries. These organic battery materials can compete with inorganic materials in terms of theoretical capacity, power and energy density. The most beneficial features of these compounds like light weight, flexibility, printability and environmental friendliness make them promising candidates for secondary organic batteries. With the vast repertoire of known redox-active species the transfer of those into a polymeric structure and their subsequent electrochemical testing can provide access to a wide variety of different electrode materials. In this thesis new polymers were developed as active battery-materials and tested for their capabilities in batteries. This includes the functionalization and optimization of well-known polymers like galvinoxyles and the incorporation of less-known redox-materials in polymeric compounds. Several new polymers, containing anode- or cathode-active compounds were synthesized. Galvinoxyl- and phenoxyl-compounds are addressed as well as quinones, anthraquinones and nitroxides. These polymeric compounds were subsequently intensively tested for their application as electrode material and incorporated into batteries, including the fabrication of a battery using inkjet-printing. By changing the functional groups of the polymers, their redox-potentials, stability or solubility are changed and new batteries were created. Those different batteries show the versatility of polymers as electrode-materials and the possibility to adjust a batteries capability to the desired specifications

Solutions for IPv6-based mobility in the EU project MobyDick

Proceedings of the WTC 2002, 18th World Telecommunications Congress, Paris, France, 22 -27 September, 2002.Mobile Internet technology is moving towards a packet-based or, more precisely, IPv6-based network. Current solutions on Mobile IPv6 and other related QoS and AAA matters do not offer the security and quality users have come to take for granted. The EU IST project Moby Dick has taken on the challenge of providing a solution that integrates QoS, mobility and AAA in a heterogeneous access environment. This paper focuses on the mobility part of the project, describes and justifies the handover approach taken, shows how QoS-aware and secure handover is achieved, and introduces the project's paging concept. It shows that a transition to a fully integrated IP-RAN and IP-Backbone has become a distinct option for the future.Publicad

Einjahresergebnisse des multimodalen Programms zur Behandlung der morbiden Adipositas des Klinikums St. Georg Leipzig

Übergewicht und Adipositas nehmen in unsere Gesellschaft einen zunehmend höheren Stellenwert ein. Diese Arbeit beschäftigt sich mit den 1-Jahresergebnissen des multimodalen Adipositasprogramms des Klinikums St. Georg. Mit der vorübergehenden Implantation eines Magenballons, einer „Very low caloried Diet“ und einer intensiven Langzeitbetreuung sollen für Patienten mit morbider Adipositas Grad III (BMI ≥ 40 kg/m²) vor einer eventuellen chirurgischen Intervention die konservativen Möglichkeiten ausgeschöpft werden. Dazu wurden folgende Fragestellungen bearbeitet: 1. Welche BMI-Reduktion und welcher EWL sind in einem Jahr möglich? 2. Gibt es abhängige Faktoren auf den Gewichtsverlust? 3. Zu welchen Veränderungen der Körperzusammensetzung kommt es im Rahmen des Gewichtsverlustes? 95 Insgesamt wurden die Ergebnisse von 65 Patienten ausgewertet, die das Programm zwischen März 2009 und Juni 2011 absolviert hatten. Mit dem Fragebogen zum Essverhalten von Pudel und Westenhöfer wurden die Störbarkeiten beim Essverhalten, sowie bereits stattgefundene Diätversuche erfasst. Außerdem konnten so Daten über den Schulabschluss und die Lebenssituation gewonnen werden. Mit der Bioelektrischen Impedanzanalyse, die in dreimonatigen Abstand durchgeführt wurde, konnte die Veränderung der Körperzusammensetzung der Patienten während der Gewichtsreduktion verfolgt werden. Nach einem Jahr zeigte sich eine hochsignifikante BMI-Reduktion von 11,2 kg/m² und ein EWL von im Mittel 35 %. Desweiteren konnte eine hochsignifikante Reduktion des Körperfetts von 26,1 kg verzeichnet werden. Patientenbezogende Faktoren, wie Geschlecht, Alter oder Bildung hatten zu keiner Zeit einen signifikanten Einfluss auf den Abnehmerfolg. So ist es Jedem möglich, in diesem konservativen Programm mit Motivation und Selbstdisziplin einen adäquaten Gewichtsverlust zu erreichen. Unsere Ergebnisse zeigen, dass im Rahmen eines multimodalen Adipositasprogramms eine signifikante Gewichtsreduktion erreicht werden kann, die mit den Ergebnissen der bariatrischen Operationen vergleichbar ist. So können in multimodalen Programmen konservative Optionen maximal ausgeschöpft und die Operationsindikation selektiver gestellt werden

Real virtuality and actual transitions: Historical reflections on virtual entities before Quantum Field Theory

This paper studies the notion of virtuality in the Bohr-Kramers-Slater theory of 1924. We situate the virtual entities of BKS within the tradition of the correspondence principle and the radiation theory of the Bohr model. We show how, in this context, virtual oscillators emerged as classical substitute radiators and were used to describe the otherwise elusive quantum transitions. They played an effective role in the quantum theory of radiation while remaining categorically distinct and ontologically separated from the quantum world of the Bohr model. The notion of virtuality thus differs markedly from its counterpart in quantum mechanics or QFT

Using Foreign Virtual Patients With Medical Students in Germany: Are Cultural Differences Evident and Do They Impede Learning?

Learning with virtual patients (VPs) is considered useful in medical education for fostering clinical reasoning. As the authoring of VPs is highly demanding, an international exchange of cases might be desirable. However, cultural differences in foreign VPs might hamper learning success

The MobyDick Project: A Mobile Heterogeneous All-IP Architecture

Proceedings of Advanced Technologies, Applications and Market Strategies for 3G (ATAMS 2001). Cracow, Poland: 17-20 June, 2001.This paper presents the current stage of an IP-based architecture for heterogeneous environments, covering UMTS-like W-CDMA wireless access technology, wireless and wired LANs, that is being developed under the aegis of the IST Moby Dick project. This architecture treats all transmission capabilities as basic physical and data-link layers, and attempts to replace all higher-level tasks by IP-based strategies. The proposed architecture incorporates aspects of mobile-IPv6, fast handover, AAA-control, and Quality of Service. The architecture allows for an optimised control on the radio link layer resources. The Moby dick architecture is currently under refinement for implementation on field trials. The services planned for trials are data transfer and voice-over-IP.Publicad

Using Foreign Virtual Patients With Medical Students in Germany: Are Cultural Differences Evident and Do They Impede Learning?

Background: Learning with virtual patients (VPs) is considered useful in medical education for fostering clinical reasoning. As the authoring of VPs is highly demanding, an international exchange of cases might be desirable. However, cultural differences in foreign VPs might hamper learning success. Objective: We investigated the need for support for using VPs from the United States at a German university, with respect to language and cultural differences. Our goal was to better understand potential implementation barriers of a intercultural VP exchange. Methods: Two VPs were presented to 30 German medical students featuring a cultural background different from German standards with respect to diagnostic and therapeutic procedures, ethical aspects, role models, and language (as identified by a cultural adaptation framework). Participants were assigned to two groups: 14 students were advised to complete the cases without further instructions (basic group), and 16 students received written explanatory supplemental information specifically with regard to cultural differences (supplement group). Using a 6-point scale (6=strongly agree), we analyzed the results of an integrated assessment of learning success as well as an evaluation of cases by the students on usefulness for learning and potential issues regarding the language and cultural background. Results: The German students found it motivating to work with cases written in English (6-point scale, 4.5 points). The clinical relevance of the VPs was clearly recognized (6 points), and the foreign language was considered a minor problem in this context (3 points). The results of the integrated learning assessment were similar in both groups (basic 53% [SD 4] vs supplement 52% [ SD 4] correct answers, P=.32). However, students using the supplemental material more readily realized culturally different diagnostic and therapeutic strategies (basic 4 vs supplement 5 points, P=.39) and were less affirmative when asked about the transferability of cases to a German context (basic 5 vs supplement 3 points, P=.048). Conclusions: German students found English VPs to be highly clinically relevant, and they rated language problems much lower than they rated motivation to work on cases in English. This should encourage the intercultural exchange of VPs. The provision of supplemental explanatory material facilitates the recognition of cultural differences and might help prevent unexpected learning effects

Einschätzung zu Fachkräften und Angebote für Familien in der Kindertagesbetreuung: Die Perspektive der Eltern. DJI-Kinderbetreuungsreport 2021. Studie 6 von 7

In Kapitel 1 werden die den Eltern bekannten Angebote der Zusammenarbeit mit den pädagogischen Fachkräften untersucht und zwischen verschiedenen Formen unterschieden: zum einen Angebote der Zusammenarbeit, die eine aktive Teilnahme der Eltern voraussetzen, und zum anderen Informationsangebote vonseiten der Kindertageseinrichtungen. Es wird aus der Perspektive der Eltern berichtet, ob es in ihrer Kindertageseinrichtung die entsprechenden Angebote gibt und ob die Eltern darüber informiert sind. Anschließend wird der Frage nachgegangen, welche Eltern seltener angeben die Angebote ihrer Kindertageseinrichtung zu kennen. Die Informationsangebote werden zudem danach untersucht, ob die Angebote für die Eltern in einem für sie ausreichendem Maß angeboten werden. Kapitel 2 widmet sich der Eltern-Fachkraft-Beziehung und zwar aus der Perspektive der Eltern. Zunächst wird anhand von drei unterschiedlichen inhaltlichen Dimensionen, dem Eltern-Fachkraft-Klima, der Kompetenzzuschreibung und dem Kritikmanagement, untersucht, wie Eltern die Beziehung zu den pädagogischen Fachkräften einschätzen. Anschließend wird anhand von verschiedenen Kind- und Familienmerkmalen analysiert, welche Eltern die Beziehung zu den pädagogischen Fachkräften in der vom Kind besuchten Einrichtung positiv bewerten und welche Familien kritischer in ihrer Einschätzung sind. Dies geschieht getrennt für die drei untersuchten Dimensionen. (DIPF/Orig.