319 research outputs found

    Las anáforas de Cotidiano del Missale hispano-mozarabicum

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    Las plegarias eucarísticas o anáforas del tiempo De Gotidiano del actual Missale Hispano-Mozarabicum constituyen una fuente de especial significación para el conocimiento de la teología eucarística del rito hispanomozárabe. Lo que aquí se pretende es una breve introducción y presentación de las características fundamentales de las anáforas cotidianas del misal hispano. Con esto, el lector puede adentrarse en los textos anafóricos del tiempo De Gotidiano o de otros tiempos del misal de 1991

    What Matters Most to Patients and Rheumatologists? A Discrete Choice Experiment in Rheumatoid Arthritis

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    Introduction: To determine patient and rheumatologist preferences for rheumatoid arthritis (RA) treatment attributes in Spain and to evaluate their attitude towards shared decision-making (SDM). Methods: Observational, descriptive, exploratory and cross-sectional study based on a discrete choice experiment (DCE). To identify the attributes and their levels, a literature review and two focus groups (patients [P] = 5; rheumatologists [R] = 4) were undertaken. Seven attributes with 2–4 levels were presented in eight scenarios. Attribute utility and relative importance (RI) were assessed using a conditional logit model. Patient preferences for SDM were assessed using an ad hoc questionnaire. Results: Ninety rheumatologists [52.2% women; mean years of experience 18.1 (SD: 9.0); seeing an average of 24.4 RA patients/week (SD: 15.3)] and 137 RA patients [mean age: 47.5 years (SD: 10.7); 84.0% women; mean time since diagnosis of RA: 14.2 years (SD: 11.8) and time in treatment: 13.2 years (SD: 11.2), mean HAQ score 1.2 (SD: 0.7)] participated in the study. In terms of RI, rheumatologists and RA patients viewed: time with optimal QoL: R: 23.41%/P: 35.05%; substantial symptom improvement: R: 13.15%/P: 3.62%; time to onset of treatment action: R: 16.24%/P: 13.56%; severe adverse events: R: 10.89%/P: 11.20%; mild adverse events: R: 4.16%/P: 0.91%; mode of administration: R: 25.23%/P: 25.00%; and added cost: R: 6.93%/P: 10.66%. Nearly 73% of RA patients were involved in treatment decision-making to a greater or lesser extent; however, 27.4% did not participate at all. Conclusion: Both for rheumatologists and patients, the top three decision-making drivers are time with optimal quality, treatment mode of administration and time to onset of action, although in different ranking order. Patients were willing to be more involved in the treatment decision-making process

    Temperature and pollution control in flames

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    We apply control theory for PDEs to flame control. The targeted flame is calculated with complex chemistry. For pollutant control in flames we study both the control of temperature distribution in the flame and flame length at given fuel rate in the flow. Approximate state and sensitivity evaluations as well as mesh adaptation are used to keep the complexity as low as possible and get mesh independent results. In addition, a new recursive semi-deterministic global optimization approach is tested

    The Potential of an Itaconic Acid Diester as EnvironmentallyFriendly Plasticizer for Injection-Molded Polylactide Parts

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    [EN] This work reports on the use of dibutyl itaconate (DBI) as an environmentallyfriendly plasticizer for polylactide (PLA) with different proportions of DBI inthe 2.5¿20 wt% (weight content) range. A co-rotating twin-screw extrusionprocess followed by injection molding is employed for the manufacturing ofthe samples. The results show that the plasticized PLA formulation with10 wt% DBI offers the most balanced overall properties, with a noticeableincrease in the elongation at break from 4.6% (neat PLA) up to 322%, with atensile modulus of 1572 MPa, and a tensile strength of 23.8 MPa. In the caseof 15 and 20 wt% DBI formulations, PLA reaches the saturation point with nomore increase in the elongation at break and a clear decrease in the tensilemodulus. DBI also decreases the glass transition temperature (Tg)from61.3°C (neat PLA) down to 23.4°C for plasticized PLA formulation containing20 wt% DBI, thus showing the high plasticization efficiency of DBI.J.I.-M. wants to thank FPU19/01759 grant funded by MCIN/AEI/10.13039/501100011033 and by ESF Investing in your future. J.G.-C. wants to thank Generalitat Valenciana-GVA, for his FPI grant (ACIF/2021/185) and grant FPU20/01732 funded by MCIN/AEI/10.13039/501100011033 and by ESF Investing in your future. Also, Microscopy Services at UPV are also acknowledged by their help in collecting and analyzing images. This research is a part of the grant PID2020-116496RB-C22 funded by MCIN/AEI/10.13039/501100011033, and the grant AICO/2021/025 funded by Generalitat Valenciana-GVAIvorra-Martínez, J.; Peydro, MA.; Gómez-Caturla, J.; Boronat, T.; Balart, R. (2022). The Potential of an Itaconic Acid Diester as EnvironmentallyFriendly Plasticizer for Injection-Molded Polylactide Parts. Macromolecular Materials and Engineering. 307(12):1-15. https://doi.org/10.1002/mame.2022003601153071

    Predicting the spread of epidemiological diseases by using a multi-objective algorithm

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    The epidemiological models are able to predict the spread of diseases, but a previous work on calibrating some involved parameters must be done. In this work, we propose a methodology to adjust those parameters based on solving a multi-objective optimization problem whose objective functions measure the accuracy of the model. More precisely, we have considered the Between-Countries Disease Spread model because it involves a set of countries taking into account the migratory movements among them. As a result, using some real data about the number of detected cases and the number of deaths for the Ebola virus disease, we have shown that the methodology is able to find a set of values for the parameters so that the model fits the outbreak spread for a set of countries

    Assessment of the mechanical and thermal properties of injection-molded poly(3-hydroxybutyrate-co-3-hydroxyhexanoate)/hydroxyapatite nanoparticles parts for use in bone tissue engineering

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    In the present study, poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) [P(3HB-co-3HHx)] was reinforced with hydroxyapatite nanoparticles (nHA) to produce novel nanocomposites for potential uses in bone reconstruction. Contents of nHA in the 2.5–20 wt % range were incorporated into P(3HB-co-3HHx) by melt compounding and the resulting pellets were shaped into parts by injection molding. The addition of nHA improved the mechanical strength and the thermomechanical resistance of the microbial copolyester parts. In particular, the addition of 20 wt % of nHA increased the tensile (Et) and flexural (Ef) moduli by approximately 64% and 61%, respectively. At the highest contents, however, the nanoparticles tended to agglomerate, and the ductility, toughness, and thermal stability of the parts also declined. The P(3HB-co-3HHx) parts filled with nHA contents of up to 10 wt % matched more closely the mechanical properties of the native bone in terms of strength and ductility when compared with metal alloys and other biopolymers used in bone tissue engineering. This fact, in combination with their biocompatibility, enables the development of nanocomposite parts to be applied as low-stress implantable devices that can promote bone reconstruction and be reabsorbed into the human body.L.Q.-C. wants to thank GVA for his FPI grant (ACIF/2016/182) and the Spanish Ministry of Education, Culture, and Sports (MECD) for his FPU grant (FPU15/03812). S.T.-G. acknowledges MICI for his Juan de la Cierva–Incorporación contract (IJCI-2016-29675). J.I.-M. wants to thank Universitat Politècnica de València for his FPI grant (PAID-2019- SP20190011). Microscopy services of the Universitat Politècnica de València (UPV) are acknowledged for their help in collecting and analyzing the FESEM images. Authors also thank Ercros S.A. for kindly supplying ErcrosBio® PH110.This research work was funded by the Spanish Ministry of Science and Innovation (MICI) project numbers RTI2018-097249-B-C21 and MAT2017-84909-C2-2-R and the POLISABIO program with grant number 2019-A02

    The effects of processing parameters on mechanical properties of 3D-printed polyhydroxyalkanoates parts

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    [EN] The crystallisation process of polyhydroxyalkanoates (PHA) polymers plays a key role on final properties of manufactured parts due to most PHA are highly sensitive to physical aging which leads to embrittlement. The secondary crystallisation associated with the aging process can be partially controlled by the cooling process during manufacturing or, even, by heat treatments such as annealing. A critical parameter in additive manufacturing is the difficulty to achieve good adhesion of the material to the printing bed. The bed temperature plays a key role on PHBH crystallisation, which leads to shrinkage having a negative effect on polymer-to-bed adhesion. In this work, a study of the effect of different processing parameters such as the printing temperature, the bed temperature, the cooling conditions, as well as raster direction on the final properties of PHBH 3D-printed parts is carried out.This research is a part of the grant PID2020-116496RB-C22 funded by MCIN/AEI/10.13039/501100011033. Authors also thank Generalitat Valenciana-GVA for funding this research through the grant numbers AICO/2021/025 and CIGE/2021/ 094. Wants to thank the Ministerio de Ciencia e Innovación and Universities for his FPU grant (FPU19/01759). Wants to thank Generalitat Valenciana-GVA, for his FPI grant (ACIF/2021/ 185) and grant FPU20/01732 funded by MCIN/AEI/10.13039/ 501100011033 and by ESF Investing in your future. Funding for open access charge: Universitat Politècnica de València.Ivorra-Martinez, J.; Peydro, MA.; Gómez-Caturla, J.; Sanchez-Nacher, L.; Boronat, T.; Balart, R. (2023). The effects of processing parameters on mechanical properties of 3D-printed polyhydroxyalkanoates parts. Virtual and Physical Prototyping (Online). 18(1). https://doi.org/10.1080/17452759.2022.216473418

    Construcción de esculturas de hormigón con elementos procedentes del reciclado

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    This paper shows the conceptual development, project, constructive and execution processes of a group of seven sculptures designed to act as containers of other art works carried out by the Spanish artist Jesús Soler. This sculptural group bases its message on the sustainability and the recycling of materials. Its fundamental boundary conditions are the capacity to be mounted and dismounted without any anchorage to the soil, durability and protection of the art work in front of meteorological agents. The sculptural group transmits by itself an environmental message. This paper describes the geometry and proportions, based on the “Le Corbusier Modulor” and the golden section, as well as all the constructive techniques applied for the correct design of each sculpture: formwork systems, concrete with recycled arid, corten steel frames, anchorages, etc. Finally the first assembly process of this itinerant sculptural work is described; it is mounted in the Parque del Retiro in the city of Madrid (Spain).Este trabajo recoge el desarrollo conceptual, de proyecto, construcción y de ejecución de un conjunto de siete esculturas disenadas para actuar como contenedores de otras obras de arte (17 cuadros) realizadas por el artista Jesús Soler. Este conjunto escultórico basa su mensaje en la sostenibidad y el reciclaje. Presenta, como condiciones de contorno fundamentales, la capacidad de ser montado y desmontado sin necesidad de anclar al terreno, durabilidad y protección de las obras frente a agentes meteorológicos y todo ello transmitiendo por sí mismas un mensaje medioambiental. Se describe en el documento la geometría y proporciones basadas en el “Modulor” de Le Corbusier y, por consiguiente, en la sección áurea, así como todas las técnicas constructivas aplicadas para el correcto diseno de cada obra: sistemas de encofrado, hormigones con áridos reciclados, marcos de acero corten, anclajes, etc. Finalmente se describe el primer proceso de montaje de esta obra itinerante, en el Parque del Retiro de Madrid
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