Data on the number and frequency of scientific literature citations for established medulloblastoma cell lines

This article collates information about the number of scientific articles mentioning each of the established medulloblastoma cell lines, derived through a systematic search of Web of Science, Scopus and Google Scholar in 2016. The data for each cell line have been presented as raw number of citations, percentage share of the total citations for each search engine and as an average percentage between the three search engines. In order to correct for the time since each cell line has been in use, the raw citation data have also been divided by the number of years since the derivation of each cell line. This is a supporting article for a review of in vitro models of medulloblastoma published in “in vitro models of medulloblastoma: choosing the right tool for the job” (D.P. Ivanov, D.A. Walker, B. Coyle, A.M. Grabowska, 2016) [1]

SMILE Maker:a web-based tool for problem solving

This paper focuses on the purposes, theoretical model, and functionality of the SMILE (Solution Mapping Intelligent Learning Environment) Maker--a World Wide Web-based problem-solving tool. From an instructional design point of view, an attempt to establish a balance between constructivism/instructivism, content-treatment interaction/aptitude-treatment interaction, and user locus of control/system locus of control is made. The model behind the SMILE Maker consists of four sub-models (user, content, instructional events, and facilitator), each built from four components. A new concept mapping method that has been developed and experimentally validated is described. Four instructional scenarios--ready-made, tailor-made, self-made, and atelier--are discussed

An Alanic marginal note and the exact date of John II's battle with the Pechenegs

Descriptive and Comparative Linguistic

Radiation of photons in process of charge particle volume reflection in bent single crystal

New type of radiation in crystals is predicted and investigated in computer simulation. It is shown that process of volume reflection of electrons and positrons in bent crystals is accomplished with high-power radiation of photons. Volume reflection radiation has intensity comparable with known channeling radiation, but it is less sensitive to entrance angle and sign of charge of a particle. Simulated spectra of radiation power are presented for 10 GeV and 200GeV particles.Comment: Latex, 8 pages, 4 fig

AdS/CFT Equivalence Transformation

We show that any conformal field theory in d-dimensional Minkowski space, in a phase with spontaneously broken conformal symmetry and with the dilaton among its fields, can be rewritten in terms of the static gauge (d-1)-brane on AdS_(d+1) by means of an invertible change of variables. This nonlinear holographic transformation maps the Minkowski space coordinates onto the brane worldvolume ones and the dilaton onto the transverse AdS brane coordinate. One of the consequences of the existence of this map is that any (d-1)-brane worldvolume action on AdS_(d+1)\times X^m (with X^m standing for the sphere S^m or more complicated curved manifold) admits an equivalent description in Minkowski space as a nonlinear and higher-derivative extension of some conventional conformal field theory action, with the conformal group being realized in a standard way. The holographic transformation explicitly relates the standard realization of the conformal group to its field-dependent nonlinear realization as the isometry group of the brane AdS_(d+1) background. Some possible implications of this transformation, in particular, for the study of the quantum effective action of N=4 super Yang-Mills theory in the context of AdS/CFT correspondence, are briefly discussed.Comment: LaTeX, 19 pages, minor correction in Abstrac

ГИПОФИЗАРНО-НАДПОЧЕЧНИКОВАЯ И ТИРЕОИДНАЯ СЕКРЕЦИЯ У СОТРУДНИКОВ МВД ПРИ РАЗЛИЧНЫХ УРОВНЯХ ПРОФЕССИОНАЛЬНОЙ НАПРЯЖЕННОСТИ

Background: A current etiological and pathogenic opinion about human health disturbance thereupon extreme factor effects is shown that this cause is principal mechanism of regulatory system (neuroimmunoendocrine complex) distress. In endocrine link occurs hormonal disbalance in hypothalamus-hypophysis axis, physiological interrelation disturbances in central – peripheral gland system (hypophysis-adrenal, hypophysis-thyroid) and metabolism abnormalities subsequently. Objective: Our aim was to determine the particular content of adrenocorticotropic and thyrothrophin hormone, cortisol, thyroxin and triiodthyronine features at law order staff in dependence from professional loading. Methods: It’s provided two investigation series among law order staff groups — combatants, ordinary policemen and military school students. The investigation period for all people corresponds to combat mission beginning and its finish. In blood serum an adrenocorticotropic (ACTH) and thyrothrophin (TSH) hormone, cortisol, thyroxin (Т4) and triiodthyronine (Т3) levels were determined. Results: A higher ACTH and TSH levels detected at combatants in both investigation series. A cortisol, Т4 and Т3 at combatants before military mission were least in comparative with other groups, but after mission it indexes were largest. Conclusion: Prolonged changes of endocrine secretory function that lead to hormonal disbalance can result to adaptation derangement. In connection with it in medical providing system for person that undergo extreme negative professional factors it’s necessary create a special endocrine link  with the view of organism resistance and life viability to extreme emergency factors and for prevention of pathological conditions. Сформированные на сегодняшний день взгляды на этиологию и патогенез нарушений состояния здоровья человека вследствие воздействия экстремальных факторов показывают, что ведущий механизм в их возникновении — напряжение регуляторных систем (нейроиммунноэндокринного комплекса). В эндокринном звене происходит разбалансировка тропных функций гипоталамо-гипофизарной оси, нарушение физиологических связей в системе центральные – периферические железы внутренней секреции (гипофиз – надпочечники, гипофиз – щитовидная железа) и, как следствие, изменение метаболизма. Цель исследования: определить особенности содержания адренокортикотропного гормона, кортизола, тиреотропного гормона, тироксина и трийодтиронина у личного состава Управления Министерства внутренних дел (МВД) России  в зависимости от уровня выполняемой ими профессиональной нагрузки. Методы: проведено 2 серии исследований среди сотрудников Управления Министерства внутренних дел России — комбатантов, рядовых полицейских и курсантов. Время обследования для всех соответствовало началу миссии на территорию с вооруженным конфликтом комбатантов и ее завершению. В сыворотке крови определены конценрации адренокортикотропного гормона (АКТГ), кортизола, тиреотропного гормона (ТТГ), тироксина (Т4) и трийдтиронина (Т3). Результаты: наиболее высокий уровень АКТГ и ТТГ отмечен в группе комбатантов в обоих исследованиях. Содержание кортизола, Т4 и Т3 у комбатантов до командировки оказалось наименьшим, в сравнении с другими группами, а после командировки — самым высоким. Заключение: длительные изменения секреторной функции эндокринной системы, приводящие к гормональному дисбалансу, могут привести к срыву адаптационного процесса. В этой связи в системе медицинского обеспечения лиц, подвергающихся воздействию экстремальных негативных профессиональных факторов, необходимо создание и полноценное функционирование эндокринологического звена с целью увеличения сопротивляемости и жизнестойкости организма к условиям экстремальных воздействий чрезвычайных ситуаций, а также предупреждения возникновения патологических состояний.

Effects of MP2RAGE B\u3csub\u3e1\u3c/sub\u3e\u3csup\u3e+\u3c/sup\u3e sensitivity on inter-site T\u3csub\u3e1\u3c/sub\u3e reproducibility and hippocampal morphometry at 7T

Most neuroanatomical studies are based on T -weighted MR images, whose intensity profiles are not solely determined by the tissue\u27s longitudinal relaxation times (T ), but also affected by varying non-T contributions, hampering data reproducibility. In contrast, quantitative imaging using the MP2RAGE sequence, for example, allows direct characterization of the brain based on the tissue property of interest. Combined with 7 Tesla (7T) MRI, this offers unique opportunities to obtain robust high-resolution brain data characterized by a high reproducibility, sensitivity and specificity. However, specific MP2RAGE parameter choices – e.g., to emphasize intracortical myelin-dependent contrast variations – can substantially impact image quality and cortical analyses through remnants of B -related intensity variations, as illustrated in our previous work. To follow up on this: we (1) validate this protocol effect using a dataset acquired with a particularly B insensitive set of MP2RAGE parameters combined with parallel transmission excitation; and (2) extend our analyses to evaluate the effects on hippocampal morphometry. The latter remained unexplored initially, but can provide important insights related to generalizability and reproducibility of neurodegenerative research using 7T MRI. We confirm that B inhomogeneities have a considerably variable effect on cortical T estimates, as well as on hippocampal morphometry depending on the MP2RAGE setup. While T differed substantially across datasets initially, we show the inter-site T comparability improves after correcting for the spatially varying B field using a separately acquired Sa2RAGE B map. Finally, removal of B residuals affects hippocampal volumetry and boundary definitions, particularly near structures characterized by strong intensity changes (e.g. cerebral spinal fluid). Taken together, we show that the choice of MP2RAGE parameters can impact T comparability across sites and present evidence that hippocampal segmentation results are modulated by B inhomogeneities. This calls for careful (1) consideration of sequence parameters when setting acquisition protocols, as well as (2) acquisition of a B map to correct MP2RAGE data for potential B variations to allow comparison across datasets. 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 + + + + + + + +

Neutron diffraction, magnetic, and magnetoelectric studies of phase transitions in multiferroic Mn0.90Co0.10WO4

We have studied various spontaneous and magnetic-field-induced phase transitions in single crystals of multiferroic Mn0.9Co0.1WO4 using magnetic and magnetoelectric measurements and neutron diffraction. Compared to pure MnWO4, our data consistently confirm that the anisotropic Co2+ ions induce reorientation of the spin cycloid structure to the ac plane and reveal Pa and Pc components of spontaneous electric polarization.Field-induced phase transitions accompanied by anomalies of magnetic susceptibility and suppression of both Pa and Pc polarizations have been observed for H∥c (∼3 T) and H∥a (∼8.5 T). Neutron diffraction has revealed that in both cases the spin cycloid plane flops in direction almost perpendicular to H, i.e., close to the ab and bc planes, respectively. Parameters describing the magnetic structures including wave vectors, orientations of the main elliptical axes, etc., have been determined in all spontaneous and field-induced states